Squarepoint affiliates report ~8.3% stakes in Cartesian Therapeutics

Cartesian Therapeutics, Inc. disclosure: multiple Squarepoint entities report beneficial ownership stakes in Common Stock totaling between 30,949 and 2,209,601 shares per entity as filed on 03/09/2026.

Rhea-AI Filing Summary

Cartesian Therapeutics, Inc. disclosure: multiple Squarepoint entities report beneficial ownership stakes in Common Stock totaling between 30,949 and 2,209,601 shares per entity as filed on 03/09/2026.

The filing lists Squarepoint Ops LLC, Squarepoint Capital LLP, Squarepoint Operations Private Limited, and Squarepoint (DIFC) Ltd each holding 2,209,601 shares (reported 8.34% of the class), Squarepoint Master Fund Limited holding 2,178,652 shares (8.22%), and Squarepoint Core Master Fund Limited holding 30,949 shares (0.12%).

Insights

Governance Analyst

Squarepoint's institutional positions cross multiple affiliates with shared voting and dispositive power.

The filing attributes shared voting and shared dispositive power to each Squarepoint affiliate: 2,209,601 shares for four affiliates, 2,178,652 for one, and 30,949 for the smaller affiliate, with percentages shown per entity.

These entries indicate coordinated holdings reported by separate legal entities; subsequent filings would clarify any consolidation of beneficial ownership or changes in voting alignment.

Quantitative Ownership Analyst

Positions represent single‑entity percentages near 8.3%, implying sizable passive stakes by funds.

The reported percentages are 8.34% per four affiliates and 8.22% for the master fund, with one small affiliate at 0.12%. Each entry ties a share count to a clear percentage in the filing.

These holdings may affect float calculations; further filings could reveal aggregated exposure or any Section 13(d) triggers if ownership is consolidated.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 03/13/2026 - 03:55 PM EDT Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

Cartesian Therapeutics, Inc.

(Name of Issuer)

Common Stock

(Title of Class of Securities)

03/09/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP Number(s):

1

Names of Reporting Persons

Squarepoint Ops LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 2,209,601.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 2,209,601.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,209,601.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.3 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

CUSIP Number(s):

1

Names of Reporting Persons

Squarepoint Capital LLP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED KINGDOM

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 2,209,601.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 2,209,601.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,209,601.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.3 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

CUSIP Number(s):

1

Names of Reporting Persons

Squarepoint Operations Private Limited

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

SINGAPORE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 2,209,601.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 2,209,601.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,209,601.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.3 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

CUSIP Number(s):

1

Names of Reporting Persons

Squarepoint (DIFC) Ltd

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED ARAB EMIRATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 2,209,601.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 2,209,601.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,209,601.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.3 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

CUSIP Number(s):

1

Names of Reporting Persons

Squarepoint Master Fund Limited

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

CAYMAN ISLANDS

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 2,178,652.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 2,178,652.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,178,652.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

8.2 %

12

Type of Reporting Person (See Instructions)

OO

SCHEDULE 13G

CUSIP Number(s):

1

Names of Reporting Persons

Squarepoint Core Master Fund Limited

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

CAYMAN ISLANDS

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 30,949.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 30,949.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

30,949.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

0.1 %

12

Type of Reporting Person (See Instructions)

OO

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Cartesian Therapeutics, Inc.
(b)	Address of issuer's principal executive offices: 7495 NEW HORIZON WAY, FREDERICK, MARYLAND, 21703.
Item 2.
(a)	Name of person filing: Squarepoint Ops LLC Squarepoint Capital LLP Squarepoint Operations Private Limited Squarepoint (DIFC) Limited Squarepoint Master Fund Limited Squarepoint Core Master Fund Limited
(b)	Address or principal business office or, if none, residence: Squarepoint Ops LLC Squarepoint Master Fund Limited Squarepoint Core Master Fund Limited 250 W 55th Street 32nd Floor, New York, NY 10019 USA Squarepoint Capital LLP Citypoint, One Ropemaker Street, London, EC2Y 9AW UK Squarepoint Operations Private Limited 88 Market Street, CapitaSpring, Level 49, 048948 Singapore Squarepoint (DIFC) Limited Unit L29-07, Level 29, ICD Brookfield Place, Dubai International Financial Centre, Dubai, United Arab Emirates
(c)	Citizenship: Squarepoint Ops LLC- USA Squarepoint Capital LLP- United Kingdom Squarepoint Operations Private Limited- Singapore Squarepoint (DIFC) Limited- United Arab Emirates Squarepoint Master Fund Limited- Cayman Islands Squarepoint Core Master Fund Limited- Cayman Islands
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 816212302
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: Squarepoint Ops LLC- 2,209,601 Squarepoint Capital LLP- 2,209,601 Squarepoint Operations Private Limited- 2,209,601 Squarepoint (DIFC) Limited- 2,209,601 Squarepoint Master Fund Limited- 2,178,652.00 Squarepoint Core Master Fund Limited- 30,949.00
(b)	Percent of class: Squarepoint Ops LLC- 8.34% Squarepoint Capital LLP- 8.34% Squarepoint Operations Private Limited- 8.34% Squarepoint (DIFC) Limited- 8.34% Squarepoint Master Fund Limited- 8.22% Squarepoint Core Master Fund Limited- 0.12%
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 0
	(ii) Shared power to vote or to direct the vote: Squarepoint Ops LLC- 2,209,601 Squarepoint Capital LLP- 2,209,601 Squarepoint Operations Private Limited- 2,209,601 Squarepoint (DIFC) Limited- 2,209,601 Squarepoint Master Fund Limited- 2,178,652.00 Squarepoint Core Master Fund Limited- 30,949.00
	(iii) Sole power to dispose or to direct the disposition of: 0
	(iv) Shared power to dispose or to direct the disposition of: Squarepoint Ops LLC- 2,209,601 Squarepoint Capital LLP- 2,209,601 Squarepoint Operations Private Limited- 2,209,601 Squarepoint (DIFC) Limited- 2,209,601 Squarepoint Master Fund Limited- 2,178,652.00 Squarepoint Core Master Fund Limited- 30,949.00
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Squarepoint Ops LLC

Signature:	/s/ John Weitzer
Name/Title:	Chief Compliance Officer
Date:	03/13/2026

Squarepoint Capital LLP

Signature:	/s/ John Weitzer
Name/Title:	Chief Compliance Officer
Date:	03/13/2026

Squarepoint Operations Private Limited

Signature:	/s/ John Weitzer
Name/Title:	Chief Compliance Officer
Date:	03/13/2026

Squarepoint (DIFC) Ltd

Signature:	/s/ John Weitzer
Name/Title:	Chief Compliance Officer
Date:	03/13/2026

Squarepoint Master Fund Limited

Signature:	/s/ John Weitzer
Name/Title:	Chief Compliance Officer
Date:	03/13/2026

Squarepoint Core Master Fund Limited

Signature:	/s/ John Weitzer
Name/Title:	Chief Compliance Officer
Date:	03/13/2026