Rein Therapeutics, Inc. SEC Filings

Rein Therapeutics, Inc. receives a Schedule 13G/A disclosing that several Voss-related entities and Travis W. Cocke hold meaningful stakes in the company. The filing reports specific beneficial ownership amounts: Voss Value Master Fund holds 699,440 shares (3.0%), Voss Value-Oriented Special Situations Fund holds 316,768 shares (1.3%), Voss Advisors GP is attributable to 1,016,208 shares (4.3%), and Voss Capital and Travis W. Cocke are each reported as beneficial owners of 2,666,532 shares (11.3%). Those percentages are calculated against 23,547,429 shares outstanding as disclosed in the issuer’s registration statement. The cover pages show sole voting and dispositive power for the reported amounts and the filing includes a certification that the shares were not acquired to change or influence control of the issuer.

Rein Therapeutics (RNTX) reports that the RENEW Phase 2 clinical trial is subject to a clinical hold, creating uncertainty about timing and the studies or actions needed to resolve the hold. The company warns that delays could strain its cash resources and affect its ability to fund the trial and operations through completion. It also notes the risk that early-stage results may not be replicated later, potential difficulties enrolling patients, and challenges integrating Qureight's deep-learning platform into the trial. The filing points readers to the company’s 2024 Form 10-K for additional risk factors and reiterates standard forward-looking statement disclaimers.

Rein Therapeutics, Inc. (RNTX) entered a Pre-Paid Advance Agreement with YA II PN, Ltd. (Yorkville) allowing up to $6.0 million of prepaid advances over 12 months, each purchased at 95% of face value and due 12 months after issuance. Interest on outstanding advances accrues at 8% annually, rising to 18% upon certain defaults. An initial $1.0 million advance was purchased on the effective date for net proceeds of $0.95 million. The company issued 479,036 shares of common stock (average price ~$1.06 per share) to Yorkville, which were applied against $500,000 of the initial advance. The placement was done in a private transaction relying on Section 4(a)(2) of the Securities Act with no underwriter.

Rein Therapeutics, Inc. (RNTX) is registering shares in connection with a standby equity purchase agreement and related prepaid advance facility with Yorkville/YA II PN, Ltd. The company is developing peptide and proenzyme candidates LTI-03 and LTI-01 for fibrosis-related lung diseases; LTI-03 is the lead program with Phase 1b data and a planned 24-week RENEW trial, with initial data expected in 2026. LTI-01 completed Phase 2a and Phase 1b work but its development has been temporarily delayed and may remain paused pending funding. Under the Pre-Paid Advance Agreement, Rein may request up to $6.0 million in prepaid advances (purchased at a 5% discount) and has received an initial $1.0 million advance (net $950,000). Under the Standby Equity Purchase Agreement, the company could receive up to $15.0 million in aggregate gross proceeds if it sells Advance Shares to the selling stockholder; outstanding and potential share counts are disclosed.

On 29 Jul 2025 Rein Therapeutics (RNTX) entered two financing arrangements with YA II PN, Ltd. 1) Pre-Paid Advance Agreement (PPA): the company can draw up to $6.0 m over 12 months; Yorkville purchases each advance at 95% of face value (initial draw $1.0 m yielded $0.95 m). Interest accrues at 8% (18% upon default). Yorkville may force repayment in shares at the lower of 115% of prior-day VWAP or 95% of the lowest VWAP in the prior 7 trading days, but not below a $0.28 floor. Floor-price, registration-effectiveness or exchange-cap breaches trigger monthly cash amortization of up to 25% of the original advance.

2) Standby Equity Purchase Agreement (SEPA): provides an equity line of up to $15.0 m over 36 months. Each advance is priced at 96% of the lowest VWAP during the three days after an advance notice, subject to volume and minimum-price limits. Rein paid a $300 k commitment fee via 213,099 shares and $25 k expenses.

The aggregate shares issuable under both facilities are capped at 19.9% of current outstanding stock, and Yorkville’s ownership is limited to 4.99%. PPA shares will be issued off the company’s shelf registration; SEPA shares require an effective resale registration statement. The facilities give Rein up to ~$21 m in gross liquidity with flexible timing, but at the cost of discounted pricing, possible dilution and potential downward pressure on the share price.

Rein Therapeutics (Nasdaq: RNTX) filed a Rule 424(b)(5) prospectus supplement that amends its May 22 2025 at-the-market (ATM) shelf with H.C. Wainwright.

The filing reduces the remaining issuance capacity under the Form S-3 from $15.77 million to $8.07 million. The cut aligns with General Instruction I.B.6, which limits sales to one-third of the company’s $42.3 million public float (calculated on July 24 2025) during any 12-month period while the float remains below $75 million.

To date the company has raised only $35,460 (16,127 shares) through the ATM. Following the adjustment, up to approximately $8.03 million of common stock can still be issued from time to time. Additional supplements will be required if a larger float later permits greater issuance capacity.

RNTX shares last closed at $1.41 on July 28 2025. Investors should evaluate the dilution risk associated with future ATM sales versus the financing flexibility this mechanism provides.

Form 4 filing: Rein Therapeutics (RNTX) disclosed that director Manuel Aivado was granted a stock option for 17,500 common shares on 23-Jul-2025 at an exercise price of $1.55 per share, expiring 22-Jul-2035.

The option vests 100 % on the earlier of 23-Jul-2026 or the 2026 annual meeting, subject to continued board service. No open-market purchases or sales of common stock were reported, and Aivado’s post-transaction derivative holdings total 17,500 options, all held directly.

This is a routine equity-based compensation grant that does not immediately alter the public float or cash position. If exercised, the award would introduce only modest dilution, typical for small-cap governance practices, while further aligning the director’s interests with shareholders.