Rhythm officer proposes sale of 57,187 shares

RHYTHM PHARMACEUTICALS, INC.

Rhea-AI Filing Summary

RHYTHM PHARMACEUTICALS, INC. (RYTM) has a notice of proposed sales under Rule 144 filed for officer Hunter Smith. The notice covers potential sales of common stock related to an exercise of stock options for 57,187 shares dated August 31, 2026, and restricted stock units for 5,587 shares dated February 1, 2026. Morgan Stanley Smith Barney LLC Executive Financial Services is listed as the broker. The filing gives advance notice of possible sales but does not itself complete any transaction.

Key Figures

Common shares from stock option exercise to be sold: 57,187 shares Common shares from restricted stock units to be sold: 5,587 shares Issuer phone number: 8572644280

3 metrics

Common shares from stock option exercise to be sold 57,187 shares Exercise of Stock Options, dated 08/31/2026, listed under Securities To Be Sold

Common shares from restricted stock units to be sold 5,587 shares Restricted Stock Units, dated 02/01/2026, listed under Securities To Be Sold

Issuer phone number 8572644280 Contact phone for RHYTHM PHARMACEUTICALS, INC.

Key Terms

Rule 144, Exercise of Stock Options, Restricted Stock Units, Executive Financial Services

4 terms

Rule 144 regulatory

"See the definition of "person" in paragraph (a) of Rule 144."

Rule 144 is a U.S. securities regulation that sets conditions under which restricted or insider-held shares can be legally resold to the public, such as required holding periods, availability of public information, limits on how much can be sold at once, and certain filing requirements. For investors it matters because it determines when previously locked-up shares can enter the market — like a release valve that can increase supply, affect share price, and signal insider intent.

Exercise of Stock Options financial

"Common | 08/31/2026 | Exercise of Stock Options | Issuer"

Restricted Stock Units financial

"Common | 02/01/2026 | Restricted Stock Units | Issuer"

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

Executive Financial Services financial

"Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza"

FAQ

What does the Form 144 filing by RYTM officer Hunter Smith disclose?

It discloses a notice of potential sales of RHYTHM PHARMACEUTICALS (RYTM) common stock under Rule 144 by officer Hunter Smith, tied to an option exercise for 57,187 shares and RSUs for 5,587 shares, with Morgan Stanley Smith Barney LLC as broker.

How many RYTM shares from stock option exercises are covered in this Form 144?

The notice lists 57,187 shares of RHYTHM PHARMACEUTICALS, INC. common stock related to an Exercise of Stock Options dated August 31, 2026, as securities to be sold under Rule 144.

How many RYTM shares from restricted stock units are included in the Form 144?

The filing lists 5,587 shares of RHYTHM PHARMACEUTICALS, INC. common stock related to Restricted Stock Units dated February 1, 2026, as securities to be sold under Rule 144.

Who is the broker for the potential RYTM share sales in this Form 144?

The broker named is Morgan Stanley Smith Barney LLC Executive Financial Services, located at 1 New York Plaza, 8th Floor, New York, NY 10004, for the proposed sales of RHYTHM PHARMACEUTICALS, INC. common stock under Rule 144.

Does this Form 144 mean RYTM shares have already been sold by Hunter Smith?

No. A Form 144 is a notice of proposed sale under Rule 144. This filing indicates an intention and eligibility to sell the listed shares but does not itself confirm that any RHYTHM PHARMACEUTICALS, INC. shares have been sold.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 08/31/2026 - 04:32 PM Accepted by SEC EDGAR 08/31/2026 - 04:32 PM Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001636385
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	RHYTHM PHARMACEUTICALS, INC.
SEC File Number	001-38223
Address of Issuer	222 Berkeley Street, 12th Floor BOSTON MASSACHUSETTS 02116
Phone	8572644280
Name of Person for Whose Account the Securities are To Be Sold	HUNTER SMITH
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza 8th Floor New York NY 10004	62774	6727489.58	68852082	08/31/2026	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	08/31/2026	Exercise of Stock Options	Issuer			57187	08/31/2026	Cash
Common	02/01/2026	Restricted Stock Units	Issuer			5587	02/01/2026	N/A

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Nothing to Report

144: Remarks and Signature

Remarks
Date of Notice	08/31/2026
Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1	05/13/2026
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ Hunter Smith
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)