STOCK TITAN

Rhythm Pharmaceu Financials

RYTM
FY2025 annual
Revenue $189.8M +45.8% YoY
Net Income -$197K +24.6% YoY
EPS (Diluted) -$3.11 +28.3% YoY
Free Cash Flow -$116.6M -2.4% YoY
Source SEC Filings (10-K/10-Q) Data as of Jun 30, 2026 Currency USD FYE December

Rhythm Pharmaceu (RYTM) reported $189.8M in revenue for fiscal year 2025, up 45.8% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 11 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI RYTM FY2025

High gross margins are scaling revenue faster, but external funding still carries a business burning -$116.6M of free cash annually.

From FY2024 to FY2025, revenue scaled materially while gross margin held at 89.7%, so the added sales did not come with weaker unit economics. Yet operating cash burn barely moved, from -$113.9M to -$115.7M, meaning the extra gross profit is still being absorbed by the cost base rather than becoming self-funding cash.

Asset-light reinvestment is unusually clear because free cash flow closely matched operating cash flow in each of the last three years, and capex was only $953K in FY2025. Cash burn is operational, not construction-heavy, so expense mix rather than physical expansion is the main driver of annual cash use.

Balance-sheet repair was meaningful: debt-to-equity fell from 5.0x in FY2024 to 0.7x in FY2025, and equity recovered to $139.1M. But financing-dependent liquidity remains the operating reality, because cash ended FY2025 at $54.3M against -$115.7M of operating cash flow, so internal cash generation is not yet carrying the model.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 54 / 100
Financial Health Score 54/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Rhythm Pharmaceu's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
27
Dilution
54
R&D Intensity
75
Revenue Progress
87
Burn Trend
51
Balance Sheet
31
Altman Z-Score Safe
10.02

Rhythm Pharmaceu scores 10.02, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($8.0B) relative to total liabilities ($341.1M). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Neutral
4/9

Rhythm Pharmaceu passes 4 of 9 financial strength tests. 1 of 4 profitability signals pass, 2 of 3 leverage/liquidity signals pass, 1 of 2 efficiency signals pass.

Earnings Quality No Cash Backing
N/A

Rhythm Pharmaceu reported a net loss of $197K while operations used $115.7M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Rhythm Pharmaceu reported an operating loss of $192.0M against $20.6M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

Export CSV

Earnings & Revenue

Revenue
$189.8M
YoY+45.8%

Rhythm Pharmaceu generated $189.8M in revenue in fiscal year 2025. This represents an increase of 45.8% from the prior year.

EBITDA
-$191.5M
YoY+27.7%

Rhythm Pharmaceu's EBITDA was -$191.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 27.7% from the prior year.

Net Income
-$197K
YoY+24.6%

Rhythm Pharmaceu reported -$197K in net income in fiscal year 2025. This represents an increase of 24.6% from the prior year.

EPS (Diluted)
-$3.11
YoY+28.3%

Rhythm Pharmaceu earned -$3.11 per diluted share (EPS) in fiscal year 2025. This represents an increase of 28.3% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$116.6M
YoY-2.4%

Rhythm Pharmaceu recorded an outflow of $116.6M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents a decrease of 2.4% from the prior year.

Cash & Debt
$54.3M
YoY-39.1%
5Y CAGR-11.6%
10Y CAGR+4.5%

Rhythm Pharmaceu held $54.3M in cash against $100.9M in long-term debt as of fiscal year 2025.

Shares Outstanding
67M
YoY+7.7%

Rhythm Pharmaceu had 67M shares outstanding in fiscal year 2025. This represents an increase of 7.7% from the prior year.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Gross Margin
89.7%
YoY0.0pp

Rhythm Pharmaceu's gross margin was 89.7% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. That is unchanged from the prior year.

Net Margin
-0.1%
YoY+0.1pp

Rhythm Pharmaceu's net profit margin was -0.1% in fiscal year 2025, showing the share of revenue converted to profit. This is up 0.1 percentage points from the prior year.

Return on Equity
-0.1%
YoY+1.1pp
5Y CAGR+80.3pp

Rhythm Pharmaceu's ROE was -0.1% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 1.1 percentage points from the prior year.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$167.3M
YoY-29.7%
5Y CAGR+13.1%
10Y CAGR+37.1%

Rhythm Pharmaceu invested $167.3M in research and development in fiscal year 2025. This represents a decrease of 29.7% from the prior year.

Capital Expenditures
$953K
5Y CAGR+34.8%
10Y CAGR+49.6%

Rhythm Pharmaceu invested $953K in capex in fiscal year 2025, funding long-term assets and infrastructure.

Share Buybacks

Not reported for fiscal year 2025.

RYTM Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

RYTM annual income statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15
Revenue$239.9M$189.8M+45.8%$130.1M+68.1%$77.4M+227.6%$23.6M+649.5%$3.2M$0$0$0$0$0N/A
Cost of Revenue$26.4M$19.5M+45.8%$13.4M+43.7%$9.3M+336.1%$2.1M+256.1%$599KN/AN/AN/AN/AN/AN/A
Gross Profit$213.5M$170.3M+45.8%$116.8M+71.4%$68.1M+216.8%$21.5M+741.7%$2.6MN/AN/AN/AN/AN/AN/A
R&D Expenses$173.2M$167.3M-29.7%$238.0M+76.3%$135.0M+24.2%$108.6M+4.3%$104.1M+15.1%$90.5M-17.4%$109.5M+117.4%$50.3M+119.9%$22.9M+16.8%$19.6M+174.1%$7.1M
SG&A Expenses$240.9M$194.9M+35.1%$144.3M+22.8%$117.5M+27.7%$92.0M+34.4%$68.5M+48.5%$46.1M+26.2%$36.5M+30.2%$28.1M+195.0%$9.5M+50.8%$6.3M+84.3%$3.4M
Operating Income-$200.6M-$192.0M+27.7%-$265.5M-44.0%-$184.4M-2.9%-$179.2M-5.3%-$170.1M-24.5%-$136.6M+6.5%-$146.0M-86.2%-$78.4M-141.9%-$32.4M-25.1%-$25.9M-145.0%-$10.6M
Interest Expense$18.5M$20.6M-0.1%$20.6M+48.3%$13.9M+167.1%$5.2MN/AN/AN/AN/AN/AN/AN/A
Income Tax$1.1M$497K+43.6%$346K-38.7%$564KN/AN/AN/AN/AN/AN/AN/AN/A
Net Income-$9.0M-$197K+24.6%-$261K-41.1%-$185K-2.0%-$181K-160.2%-$70K+99.9%-$134.0M+4.8%-$140.7M-90.0%-$74.1M-119.7%-$33.7M-30.3%-$25.9M-133.6%-$11.1M
EPS (Diluted)-$3.11+28.3%-$4.34-35.6%-$3.20+7.8%-$3.47-147.9%-$1.40-$3.04+21.2%-$3.86N/AN/AN/AN/A

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

RYTM Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

RYTM annual balance sheet
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15
Total Assets$480.2M+22.4%$392.3M+17.9%$332.7M-13.0%$382.5M+16.1%$329.5M+76.1%$187.1M-39.4%$308.5M+18.6%$260.2M+71.5%$151.7M+1129.7%$12.3MN/A
Current Assets$466.9M+24.8%$374.2M+21.4%$308.3M-13.0%$354.2M+14.9%$308.4M+69.8%$181.7M-39.9%$302.4M+16.9%$258.7M+71.7%$150.7M+1248.3%$11.2MN/A
Cash & Equivalents$54.3M-39.1%$89.1M+48.4%$60.1M-52.9%$127.7M+115.5%$59.2M-41.3%$100.9M+61.9%$62.3M+25.7%$49.5M+44.7%$34.2M+423.5%$6.5M-81.2%$34.9M
Inventory$25.8M+37.4%$18.7M+117.3%$8.6M+195.6%$2.9M+2527.9%$111KN/AN/AN/AN/AN/AN/A
Accounts Receivable$26.1M+40.9%$18.5M+24.5%$14.9M+138.9%$6.2M+507.2%$1.0MN/AN/AN/AN/AN/AN/A
Total Liabilities$341.1M-7.9%$370.5M+127.3%$163.0M+37.9%$118.2M+160.6%$45.4M+120.8%$20.5M-25.3%$27.5M+97.1%$14.0M+100.8%$6.9M-84.6%$45.0MN/A
Current Liabilities$105.9M-8.3%$115.5M+109.3%$55.2M+38.7%$39.8M-8.3%$43.4M+141.3%$18.0M-26.3%$24.4M+79.8%$13.6M+102.1%$6.7M+42.0%$4.7MN/A
Long-Term Debt$100.9M-6.8%$108.3M+2.0%$106.1MN/AN/AN/AN/AN/AN/AN/AN/A
Total Equity$139.1M+540.0%$21.7M-87.2%$169.8M-35.8%$264.3M-7.0%$284.2M+70.6%$166.5M-40.7%$281.0M+14.1%$246.3M+70.1%$144.8M+542.7%-$32.7M-308.8%-$8.0M
Retained Earnings-$1.4B-17.0%-$1.2B-29.1%-$894.7M-26.0%-$710.1M-34.2%-$528.9M-15.2%-$459.3M-41.2%-$325.3M-76.2%-$184.6M-67.4%-$110.3M-44.0%-$76.5MN/A

Not reported in any period shown, so not listed: Goodwill.

RYTM Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

RYTM annual cash flow statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15
Operating Cash Flow-$105.3M-$115.7M-1.6%-$113.9M+16.4%-$136.2M+21.5%-$173.4M-18.8%-$146.0M-19.7%-$122.0M+0.6%-$122.8M-97.8%-$62.1M-110.6%-$29.5M-26.9%-$23.2M-243.9%-$6.8M
Capital ExpendituresN/A$953K$0-100.0%$47K-83.3%$281K-35.3%$434K+102.8%$214K-93.7%$3.4M+368.8%$722K+442.9%$133K-87.4%$1.1M+6117.6%$17K
Free Cash FlowN/A-$116.6M-2.4%-$113.9M+16.4%-$136.2M+21.6%-$173.7M-18.6%-$146.4M-19.8%-$122.2M+3.1%-$126.1M-100.9%-$62.8M-112.1%-$29.6M-21.9%-$24.3M-258.6%-$6.8M
Investing Cash Flow-$144.9M-$137.2M-184.7%-$48.2M-750.4%-$5.7M-120.2%$28.0M+145.1%-$62.2M-139.2%$158.5M+666.8%-$28.0M+67.9%-$87.1M+20.8%-$110.0M-2053.5%-$5.1M-29958.8%-$17K
Financing Cash Flow$179.8M$218.0M+14.0%$191.2M+157.2%$74.4M-65.2%$213.8M+28.4%$166.5M+8186.8%$2.0M-98.8%$163.5M-0.7%$164.7M-1.5%$167.2MN/A$41.7M

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

RYTM Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

RYTM annual financial ratios
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15
Gross Margin89.7%0.0pp89.7%+1.7pp88.0%-3.0pp91.0%+10.0pp81.0%N/AN/AN/AN/AN/AN/A
Operating Margin-101.2%-204.0%-238.1%-757.9%-5391.9%N/AN/AN/AN/AN/AN/A
Net Margin-0.1%+0.1pp-0.2%0.0pp-0.2%+0.5pp-0.8%+1.4pp-2.2%N/AN/AN/AN/AN/AN/A
Return on Equity-0.1%+1.1pp-1.2%-1.1pp-0.1%0.0pp-0.1%-0.1pp0.0%+80.4pp-80.5%-30.4pp-50.1%-20.0pp-30.1%-6.8pp-23.3%N/AN/A
Return on Assets0.0%0.0pp-0.1%0.0pp-0.1%0.0pp-0.1%0.0pp0.0%+71.6pp-71.6%-26.0pp-45.6%-17.1pp-28.5%-6.2pp-22.2%+187.5pp-209.7%N/A
Current Ratio4.41+1.2x3.24-2.3x5.58-3.3x8.90+1.8x7.10-3.0x10.10-2.3x12.38-6.7x19.05-3.4x22.42+20.1x2.36N/A
Debt-to-Equity0.73-4.3x4.98+4.4x0.63+0.2x0.45+0.3x0.160.0x0.120.0x0.100.0x0.060.0x0.05N/AN/A
FCF Margin-61.5%+26.0pp-87.5%-175.9%-734.9%-4642.9%N/AN/AN/AN/AN/AN/A

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, FCF Margin.

Similar Companies

Frequently Asked Questions

What is Rhythm Pharmaceu's annual revenue?

Rhythm Pharmaceu (RYTM) reported $189.8M in total revenue for fiscal year 2025. This represents a 45.8% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Rhythm Pharmaceu's revenue growing?

Rhythm Pharmaceu (RYTM) revenue grew by 45.8% year-over-year, from $130.1M to $189.8M in fiscal year 2025.

Is Rhythm Pharmaceu profitable?

No, Rhythm Pharmaceu (RYTM) reported a net income of -$197K in fiscal year 2025, with a net profit margin of -0.1%.

Rhythm Pharmaceu (RYTM) reported diluted earnings per share of -$3.11 for fiscal year 2025. This represents a 28.3% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Rhythm Pharmaceu (RYTM) had EBITDA of -$191.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Rhythm Pharmaceu (RYTM) had $54.3M in cash and equivalents against $100.9M in long-term debt.

Rhythm Pharmaceu (RYTM) had a gross margin of 89.7% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.

Rhythm Pharmaceu (RYTM) had a net profit margin of -0.1% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Rhythm Pharmaceu (RYTM) has a return on equity of -0.1% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Rhythm Pharmaceu (RYTM) recorded an outflow of $116.6M in free cash flow during fiscal year 2025. This represents a -2.4% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Rhythm Pharmaceu (RYTM) recorded an outflow of $115.7M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Rhythm Pharmaceu (RYTM) had $480.2M in total assets as of fiscal year 2025, including both current and long-term assets.

Rhythm Pharmaceu (RYTM) invested $953K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Rhythm Pharmaceu (RYTM) invested $167.3M in research and development during fiscal year 2025.

Rhythm Pharmaceu (RYTM) had 67M shares outstanding as of fiscal year 2025.

Rhythm Pharmaceu (RYTM) had a current ratio of 4.41 as of fiscal year 2025, which is generally considered healthy.

Rhythm Pharmaceu (RYTM) had a debt-to-equity ratio of 0.73 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Rhythm Pharmaceu (RYTM) had a return on assets of 0.0% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Rhythm Pharmaceu (RYTM) had $54.3M in cash against an annual operating cash burn of $115.7M. This gives an estimated cash runway of approximately 6 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Rhythm Pharmaceu (RYTM) has an Altman Z-Score of 10.02, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Rhythm Pharmaceu (RYTM) has a Piotroski F-Score of 4 out of 9, indicating neutral financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Rhythm Pharmaceu (RYTM) reported a net loss of $197K while operations used $115.7M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Rhythm Pharmaceu (RYTM) reported an operating loss of $192.0M against $20.6M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Rhythm Pharmaceu (RYTM) scores 54 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

Back to top