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Cytokinetics Inc Financials

CYTK
FY2025 annual
Revenue $88.0M +376.6% YoY
Net Income -$785.0M -33.2% YoY
EPS (Diluted) -$6.54 -24.3% YoY
Free Cash Flow -$534.8M -33.8% YoY
Source SEC Filings (10-K/10-Q) Data as of Jun 30, 2026 Currency USD FYE December

Cytokinetics Inc (CYTK) reported $88.0M in revenue for fiscal year 2025, up 376.6% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 15 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI CYTK FY2025

External financing, not product revenue, is still carrying the business as R&D-heavy spending outruns cash generated by operations.

In FY2025, -$510M of operating cash outflow was almost entirely offset by $524M of financing inflow. With revenue at only $88M, that cash replacement cycle explains how a 4.5x current ratio can coexist with negative equity.

The cost structure is centered on development investment, not current commercial scale: FY2025 R&D reached $416M against revenue of $88M. Because overhead also expanded, the revenue rebound did not make the operating model meaningfully lighter.

The balance sheet combines strong near-term liquidity with weak accumulated capital: current assets of $917M covered current liabilities of $202M. But total liabilities of $2.08B exceeded total assets of $1.42B, so the business is being financed by continued capital access rather than by retained earnings or internally generated cash.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 48 / 100
Financial Health Score 48/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Cytokinetics Inc's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
15
Dilution
46
R&D Intensity
83
Revenue Progress
98
Burn Trend
33
Balance Sheet
15
Altman Z-Score Distress
-1.07

Cytokinetics Inc scores -1.07, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($10.8B) relative to total liabilities ($2.1B). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
2/8

Cytokinetics Inc passes 2 of 8 computable financial strength tests (1 of the nine could not be computed from available data). 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), both operating efficiency signals pass.

Earnings Quality No Cash Backing
N/A

Cytokinetics Inc reported a net loss of $785.0M while operations used $510.0M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Cytokinetics Inc reported an operating loss of $612.3M against $45.6M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

Revenue
$88.0M
YoY+376.6%
5Y CAGR+9.5%
10Y CAGR+11.9%

Cytokinetics Inc generated $88.0M in revenue in fiscal year 2025. This represents an increase of 376.6% from the prior year.

EBITDA
-$602.1M
YoY-14.3%

Cytokinetics Inc's EBITDA was -$602.1M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 14.3% from the prior year.

Net Income
-$785.0M
YoY-33.2%

Cytokinetics Inc reported -$785.0M in net income in fiscal year 2025. This represents a decrease of 33.2% from the prior year.

EPS (Diluted)
-$6.54
YoY-24.3%

Cytokinetics Inc earned -$6.54 per diluted share (EPS) in fiscal year 2025. This represents a decrease of 24.3% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$534.8M
YoY-33.8%

Cytokinetics Inc recorded an outflow of $534.8M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents a decrease of 33.8% from the prior year.

Cash & Debt
$122.5M
YoY+29.2%
5Y CAGR+8.1%
10Y CAGR+6.5%

Cytokinetics Inc held $122.5M in cash against $246.4M in long-term debt as of fiscal year 2025.

Shares Outstanding
123M
YoY+4.0%
5Y CAGR+11.6%
10Y CAGR+12.0%

Cytokinetics Inc had 123M shares outstanding in fiscal year 2025. This represents an increase of 4.0% from the prior year.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Gross Margin

Not reported for fiscal year 2025.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Return on Equity

Not reported for fiscal year 2025.

Capital Allocation

R&D Spending
$416.0M
YoY+22.6%
5Y CAGR+33.8%
10Y CAGR+24.5%

Cytokinetics Inc invested $416.0M in research and development in fiscal year 2025. This represents an increase of 22.6% from the prior year.

Capital Expenditures
$24.8M
YoY+535.1%
5Y CAGR+17.6%
10Y CAGR+46.0%

Cytokinetics Inc invested $24.8M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 535.1% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

CYTK Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

CYTK annual income statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Revenue$67.7M$88.0M+376.6%$18.5M+145.3%$7.5M-92.0%$94.6M+34.3%$70.4M+26.2%$55.8M+107.8%$26.9M-14.7%$31.5M+135.6%$13.4M-87.4%$106.4M+271.3%$28.7M-38.9%$46.9M+53.2%$30.6M+305.5%$7.6M+89.0%$4.0M
R&D Expenses$401.0M$416.0M+22.6%$339.4M+2.8%$330.1M+37.1%$240.8M+50.6%$159.9M+65.0%$97.0M+12.6%$86.1M-3.4%$89.1M-1.3%$90.3M+50.8%$59.9M+29.1%$46.4M+4.4%$44.4M-10.2%$49.5M+38.7%$35.6M-4.1%$37.2M
SG&A Expenses$370.5M$284.3M+32.0%$215.3M+24.0%$173.6M-2.5%$178.0M+83.9%$96.8M+83.3%$52.8M+33.4%$39.6M+26.6%$31.3M-14.2%$36.5M+31.1%$27.8M+41.5%$19.7M+13.9%$17.3M+14.4%$15.1M+21.4%$12.4M-8.5%$13.6M
Operating Income-$707.9M-$612.3M-14.2%-$536.2M-8.1%-$496.2M-53.1%-$324.2M-74.0%-$186.3M-98.3%-$93.9M+5.0%-$98.9M-11.2%-$88.9M+21.6%-$113.4M-706.8%$18.7M+150.0%-$37.4M-153.5%-$14.8M+56.5%-$33.9M+16.2%-$40.5M+15.7%-$48.0M
Interest ExpenseN/A$45.6M+20.9%$37.7M+33.2%$28.3M+45.8%$19.4M+18.1%$16.4M+3.0%$16.0M+141.0%$6.6M+74.4%$3.8M+25.9%$3.0M+11.8%$2.7M+906.7%$268K$0$0-100.0%$3K-91.4%$35K
Income TaxN/A$0$0$0$0$0$0$0$0$0$0$0$0$0$0$0
Net Income-$894.0M-$785.0M-33.2%-$589.5M-12.0%-$526.2M-35.3%-$389.0M-80.6%-$215.3M-69.2%-$127.3M-4.6%-$121.7M-14.5%-$106.3M+16.8%-$127.8M-876.7%$16.5M+143.9%-$37.5M-156.0%-$14.6M+56.6%-$33.7M+16.5%-$40.4M+15.6%-$47.9M
EPS (Diluted)-$6.54-24.3%-$5.26+3.5%-$5.45-25.9%-$4.33-54.6%-$2.80-42.1%-$1.97N/AN/A-$2.59-764.1%$0.39+140.2%-$0.97-136.6%-$0.41N/AN/A-$0.72

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

CYTK Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

CYTK annual balance sheet
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Total Assets$1.4B+1.6%$1.4B+70.0%$824.3M-18.8%$1.0B+20.6%$841.3M+57.6%$533.8M+84.2%$289.8M+37.2%$211.2M-28.4%$294.8M+73.3%$170.1M+47.6%$115.2M-13.3%$133.0M+59.8%$83.2M+7.3%$77.6M+47.0%$52.8M
Current Assets$917.0M-17.2%$1.1B+76.4%$628.1M-21.0%$795.2M+48.4%$535.7M+13.0%$474.2M+102.9%$233.8M+12.6%$207.7M-24.3%$274.3M+72.9%$158.6M+40.3%$113.1M-13.7%$131.1M+65.3%$79.3M+3.8%$76.4M+49.4%$51.1M
Cash & Equivalents$122.5M+29.2%$94.9M-16.1%$113.0M+72.3%$65.6M-41.8%$112.7M+35.8%$83.0M+127.8%$36.4M-13.8%$42.3M-66.3%$125.2M+87.2%$66.9M+2.8%$65.1M+221.9%$20.2M+0.3%$20.2M+35.2%$14.9M-20.8%$18.8M
Inventory$0N/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Accounts Receivable$17.8M+6.7%$16.6M+1197.7%$1.3M+772.8%$147K-99.7%$51.8M+1072.4%$4.4M-14.4%$5.2M+131.4%$2.2M+100.6%$1.1M+4533.3%$24KN/AN/AN/AN/AN/A
Total Liabilities$2.1B+35.6%$1.5B+27.0%$1.2B+7.8%$1.1B+87.9%$597.5M+42.1%$420.4M+39.8%$300.8M+62.4%$185.2M+0.1%$185.0M+144.1%$75.8M+62.5%$46.6M+14.0%$40.9M+42.3%$28.7M+285.0%$7.5M+62.5%$4.6M
Current Liabilities$202.5M+12.7%$179.7M+75.0%$102.7M+21.3%$84.6M+17.8%$71.9M+130.3%$31.2M+19.9%$26.0M+17.3%$22.2M-31.6%$32.4M-2.4%$33.3M+5.1%$31.6M+32.7%$23.9M-10.7%$26.7M+275.8%$7.1M+54.7%$4.6M
Long-Term Debt$246.4M+164.3%$93.2M+59.7%$58.4M-8.5%$63.8M+34.7%$47.4M+2.5%$46.2M+2.6%$45.1M+13.2%$39.8M+25.3%$31.8M+16.1%$27.4M+87.0%$14.6M$0N/AN/AN/A
Total Equity-$659.6M-387.3%-$135.4M+65.0%-$386.3M-258.0%-$107.9M-144.2%$243.9M+115.1%$113.4M+1136.7%-$10.9M-142.2%$25.9M-76.4%$109.8M+16.4%$94.4M+37.6%$68.6M-25.5%$92.1M+69.1%$54.4M-22.3%$70.1M+45.5%$48.2M
Retained Earnings-$3.5B-29.1%-$2.7B-27.9%-$2.1B-33.2%-$1.6B-31.3%-$1.2B-21.7%-$992.3M-14.7%-$865.0M-16.4%-$743.3M-15.1%-$646.1M-24.7%-$518.3M+3.1%-$534.7M-7.5%-$497.2M-3.0%-$482.6M-7.5%-$448.9M-9.9%-$408.5M

Not reported in any period shown, so not listed: Goodwill.

CYTK Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

CYTK annual cash flow statement
MetricTTMFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Operating Cash Flow-$555.5M-$510.0M-28.8%-$395.9M+4.5%-$414.3M-38.3%-$299.5M-110.2%-$142.5M-1693.7%$8.9M+109.8%-$90.9M+10.2%-$101.2M+0.5%-$101.8M-375.2%$37.0M+657.4%$4.9M+110.9%-$44.8M-481.0%-$7.7M+76.9%-$33.4M+26.7%-$45.6M
Capital Expenditures$25.3M$24.8M+535.1%$3.9M+175.8%$1.4M-87.5%$11.3M-76.8%$48.9M+342.2%$11.1M+322.0%$2.6M+194.6%$889K-69.1%$2.9M+80.3%$1.6M+184.0%$562K-49.1%$1.1M+103.7%$542K+333.6%$125K-71.8%$443K
Free Cash Flow-$580.7M-$534.8M-33.8%-$399.8M+3.8%-$415.7M-33.7%-$310.9M-62.4%-$191.4M-8975.1%-$2.1M+97.7%-$93.5M+8.4%-$102.1M+2.4%-$104.6M-395.7%$35.4M+718.9%$4.3M+109.4%-$45.9M-456.3%-$8.3M+75.4%-$33.6M+27.1%-$46.0M
Investing Cash Flow-$503.7M$16.7M+103.0%-$553.1M-331.2%$239.3M+191.3%-$262.1M-77.4%-$147.8M+24.8%-$196.5M-163.0%-$74.7M-1555.4%$5.1M+107.8%-$65.8MN/AN/AN/A-$1.5M+94.7%-$28.8M-213.9%$25.3M
Financing Cash Flow$1.2B$524.5M-43.6%$930.6M+320.5%$221.3M-57.1%$516.2M+61.3%$320.0M+36.7%$234.1M+46.5%$159.8M+1116.8%$13.1M-94.2%$225.9MN/AN/AN/A$14.5M-75.2%$58.3M+169.9%$21.6M

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

TTM is the trailing twelve months, Q3 FY2025 through Q2 FY2026, summed from the four most recent quarterly filings. A row marked — cannot be summed at all, because a quarter in the window reports no per-share figure; a row marked N/A could be summed, but a quarter in the window does not report that metric.

CYTK Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

CYTK annual financial ratios
MetricFY25FY24FY23FY22FY21FY20FY19FY18FY17FY16FY15FY14FY13FY12FY11
Operating Margin-695.4%-2902.7%-6589.7%-342.8%-264.5%-168.3%-368.0%-282.3%-848.3%17.6%-130.5%-31.4%-110.6%-535.2%-1199.1%
Net Margin-891.6%-3191.1%-6988.6%-411.2%-305.7%-228.0%-452.9%-337.4%-955.9%15.5%-130.9%-31.2%-110.0%-534.1%-1196.5%
Return on EquityN/AN/AN/AN/A-88.3%+24.0pp-112.3%N/A-409.8%-293.5pp-116.3%-133.8pp17.4%+72.1pp-54.7%-38.8pp-15.9%+46.0pp-61.9%-4.3pp-57.6%+41.7pp-99.3%
Return on Assets-55.1%-13.0pp-42.1%+21.8pp-63.8%-25.5pp-38.3%-12.7pp-25.6%-1.7pp-23.8%+18.1pp-42.0%+8.3pp-50.3%-7.0pp-43.4%-53.0pp9.7%+42.2pp-32.5%-21.5pp-11.0%+29.5pp-40.5%+11.5pp-52.1%+38.6pp-90.7%
Current Ratio4.53-1.6x6.170.0x6.12-3.3x9.40+1.9x7.45-7.7x15.20+6.2x8.98-0.4x9.36+0.9x8.45+3.7x4.77+1.2x3.57-1.9x5.50+2.5x2.97-7.8x10.76-0.4x11.14
Debt-to-EquityN/AN/AN/AN/A0.19-0.2x0.41N/A1.53+1.2x0.290.0x0.29+0.1x0.21+0.2x0.00-0.5x0.53+0.4x0.110.0x0.10
FCF Margin-607.5%-2164.1%-5521.2%-328.6%-271.8%-3.8%-348.1%-324.1%-782.7%33.3%+18.2pp15.1%+113.0pp-97.9%-70.9pp-27.0%-444.0%-1150.9%

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

Note: Shareholder equity is negative (-$659.6M), which causes debt-to-equity and return on equity ratios to appear negative or not meaningful. This can occur from accumulated losses or large share buyback programs.

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Frequently Asked Questions

What is Cytokinetics Inc's annual revenue?

Cytokinetics Inc (CYTK) reported $88.0M in total revenue for fiscal year 2025. This represents a 376.6% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Cytokinetics Inc's revenue growing?

Cytokinetics Inc (CYTK) revenue grew by 376.6% year-over-year, from $18.5M to $88.0M in fiscal year 2025.

Is Cytokinetics Inc profitable?

No, Cytokinetics Inc (CYTK) reported a net income of -$785.0M in fiscal year 2025.

Cytokinetics Inc (CYTK) reported diluted earnings per share of -$6.54 for fiscal year 2025. This represents a -24.3% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Cytokinetics Inc (CYTK) had EBITDA of -$602.1M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Cytokinetics Inc (CYTK) had $122.5M in cash and equivalents against $246.4M in long-term debt.

Cytokinetics Inc (CYTK) recorded an outflow of $534.8M in free cash flow during fiscal year 2025. This represents a -33.8% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Cytokinetics Inc (CYTK) recorded an outflow of $510.0M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Cytokinetics Inc (CYTK) had $1.4B in total assets as of fiscal year 2025, including both current and long-term assets.

Cytokinetics Inc (CYTK) invested $24.8M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Cytokinetics Inc (CYTK) invested $416.0M in research and development during fiscal year 2025.

Cytokinetics Inc (CYTK) had 123M shares outstanding as of fiscal year 2025.

Cytokinetics Inc (CYTK) had a current ratio of 4.53 as of fiscal year 2025, which is generally considered healthy.

Cytokinetics Inc (CYTK) had a return on assets of -55.1% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Cytokinetics Inc (CYTK) had $122.5M in cash against an annual operating cash burn of $510.0M. This gives an estimated cash runway of approximately 3 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Cytokinetics Inc (CYTK) has negative shareholder equity of -$659.6M as of fiscal year 2025, so no debt-to-equity ratio is reported: dividing debt by equity that is not positive produces a number that cannot be read as leverage. This can occur when accumulated losses exceed invested capital, or after large share buyback programs. Other solvency metrics like the current ratio or interest coverage may be more informative.

Cytokinetics Inc (CYTK) has an Altman Z-Score of -1.07, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Cytokinetics Inc (CYTK) has a Piotroski F-Score of 2 out of 8 computable signals; 1 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Cytokinetics Inc (CYTK) reported a net loss of $785.0M while operations used $510.0M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Cytokinetics Inc (CYTK) reported an operating loss of $612.3M against $45.6M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Cytokinetics Inc (CYTK) scores 48 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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