SAB Biotherapeutics, Inc. received an amended Schedule 13G indicating that Vivo Opportunity Fund Holdings, L.P. and its general partner Vivo Opportunity, LLC may be deemed to beneficially own 22,637,108 shares of common stock and equivalents, while Vivo Opportunity Cayman Fund, L.P. and its general partner Vivo Opportunity Cayman, LLC may be deemed to beneficially own 2,286,301 shares.
These positions include existing common shares plus shares issuable upon conversion of Series B Preferred Stock and upon exercise of related Enrollment Warrants and Data Release Warrants that are exercisable or convertible within 60 days. Each reporting person reports beneficial ownership of 9.99% of the common stock class, with blocking provisions in the preferred stock and warrants that prevent conversions or exercises which would increase ownership above 9.99% of the issuer’s voting securities.
Positive
None.
Negative
None.
Key Figures
Beneficial ownership – Vivo Opportunity, LLC:22,637,108 sharesBeneficial ownership – Vivo Opportunity Cayman, LLC:2,286,301 sharesCommon stock held – Vivo Opportunity, LLC:6,632,508 shares+4 more
7 metrics
Beneficial ownership – Vivo Opportunity, LLC22,637,108 sharesAggregate SAB Biotherapeutics securities beneficially owned, including common, Series B Preferred, and warrants
Beneficial ownership – Vivo Opportunity Cayman, LLC2,286,301 sharesAggregate SAB Biotherapeutics securities beneficially owned via Cayman fund structure
Common stock held – Vivo Opportunity, LLC6,632,508 sharesPortion of the 22,637,108-share beneficial ownership that is existing common stock
Common stock held – Vivo Opportunity Cayman, LLC667,401 sharesPortion of the 2,286,301-share beneficial ownership that is existing common stock
Ownership cap9.99%Maximum voting securities ownership allowed under Series B Preferred and warrant blocking provisions
Shares from Enrollment Warrants – Vivo Opportunity, LLC10,372,400 sharesCommon stock issuable upon conversion of Series B Preferred underlying 103,724 Enrollment Warrants
Shares from Enrollment Warrants – Vivo Opportunity Cayman, LLC1,047,600 sharesCommon stock issuable upon conversion of Series B Preferred underlying 10,476 Enrollment Warrants
Key Terms
beneficially own, Series B Preferred Stock, Enrollment Warrants, Data Release Warrants, +1 more
5 terms
beneficially ownfinancial
"Vivo Opportunity, LLC may be deemed to beneficially own an aggregate of 22,637,108 shares"
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
Series B Preferred Stockfinancial
"shares of Common Stock issuable upon conversion of shares of the Issuer's Series B Preferred Stock"
Series B preferred stock is a type of ownership share issued by a company that offers certain advantages over common stock, such as priority in receiving dividends or assets if the company is sold or liquidated. It is typically issued after an initial round of funding, making it a way for investors to support a company's growth while gaining some protections and benefits. This stock matters to investors because it often provides a more secure investment position with potential for future growth.
Enrollment Warrantsfinancial
"Series B Preferred Stock underlying 103,724 Enrollment Warrants that are exercisable within 60 days"
Data Release Warrantsfinancial
"Series B Preferred Stock underlying 51,862 Data Release Warrants that are exercisable within 60 days"
blocking provisionsfinancial
"contain provisions preventing these securities from being converted or exercised into shares of Common Stock"
FAQ
What ownership stake in SABS does Vivo Opportunity Fund Holdings report?
Vivo Opportunity Fund Holdings, L.P. and its general partner report beneficial ownership of 22,637,108 shares of SAB Biotherapeutics securities, including common stock and shares issuable from Series B Preferred Stock, Enrollment Warrants, and Data Release Warrants exercisable or convertible within 60 days.
What percentage of SAB Biotherapeutics (SABS) is held by each Vivo reporting entity?
Each of the four Vivo reporting entities reports beneficial ownership of 9.99% of SAB Biotherapeutics’ common stock class. This percentage reflects shares outstanding plus shares issuable from preferred stock and warrants, calculated without applying the 9.99% ownership blocking provisions.
How many SABS common shares does Vivo Opportunity Cayman Fund beneficially own?
Vivo Opportunity Cayman Fund, L.P. and its general partner may be deemed to beneficially own 2,286,301 shares of SAB Biotherapeutics securities, including 667,401 common shares and additional shares issuable from Series B Preferred Stock and related warrants within 60 days.
What are the blocking provisions affecting Vivo’s SABS preferred stock and warrants?
The Series B Preferred Stock, Enrollment Warrants, and Data Release Warrants contain provisions preventing conversion or exercise into common stock if doing so would cause the holder or its affiliates to exceed 9.99% of SAB’s voting securities, effectively capping voting ownership.
How are Vivo’s SABS securities structured between common stock and derivatives?
For Vivo Opportunity, LLC, the 22,637,108 shares include 6,632,508 common shares plus shares issuable from 4,460 Series B Preferred shares and from Enrollment and Data Release Warrants. A similar mix applies to the 2,286,301 shares held via the Cayman entities.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 1)
SAB Biotherapeutics, Inc.
(Name of Issuer)
Common Stock, par value $0.0001 per share
(Title of Class of Securities)
78397T202
(CUSIP Number)
06/30/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
78397T202
1
Names of Reporting Persons
Vivo Opportunity Fund Holdings, L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
22,637,108.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
22,637,108.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
22,637,108.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.99 %
12
Type of Reporting Person (See Instructions)
PN
Comment for Type of Reporting Person: The reported share amount represents an aggregate of (i) 6,632,508 shares of common stock, par value $0.0001 per share (the "Common Stock") of SAB Biotherapeutics, Inc. (the "Issuer"), (ii) 446,000 shares of Common Stock issuable upon conversion of 4,460 shares of the Issuer's Series B Preferred Stock, par value $0.0001 per share (the "Series B Preferred Stock") convertible within 60 days of this Statement, (iii) 10,372,400 shares of Common Stock issuable upon conversion of 103,724 shares of Series B Preferred Stock underlying 103,724 Enrollment Warrants that are exercisable within 60 days of this Statement, and (iv) 5,186,200 shares of Common Stock issuable upon conversion of 51,862 shares of Series B Preferred Stock underlying 51,862 Data Release Warrants that are exercisable within 60 days of this Statement. All securities are held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P.
The Series B Preferred Stock, the Enrollment Warrants and the Data Release Warrant all contain provisions preventing these securities from being converted or exercised into shares of Common Stock, if such conversion or exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities. However, the amounts reported in rows 5, 7 and 9 herein represent the number of shares of Common Stock that would be issuable upon full exercise of the Enrollment Warrants and the Data Release Warrants into Series B Preferred Stock and the full conversion of Series B Preferred Stock to shares of Common Stock, without giving effect to the blocking provisions.
SCHEDULE 13G
CUSIP Number(s):
78397T202
1
Names of Reporting Persons
Vivo Opportunity, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
22,637,108.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
22,637,108.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
22,637,108.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.99 %
12
Type of Reporting Person (See Instructions)
OO
Comment for Type of Reporting Person: The reported share amount represents an aggregate of (i) 6,632,508 shares of Common Stock of the Issuer, (ii) 446,000 shares of Common Stock issuable upon conversion of 4,460 shares of the Issuer's Series B Preferred Stock, convertible within 60 days of this Statement, (iii) 10,372,400 shares of Common Stock issuable upon conversion of 103,724 shares of Series B Preferred Stock underlying 103,724 Enrollment Warrants that are exercisable within 60 days of this Statement, and (iv) 5,186,200 shares of Common Stock issuable upon conversion of 51,862 shares of Series B Preferred Stock underlying 51,862 Data Release Warrants that are exercisable within 60 days of this Statement. All securities are held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P.
The Series B Preferred Stock, the Enrollment Warrants and the Data Release Warrant all contain provisions preventing these securities from being converted or exercised into shares of Common Stock, if such conversion or exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities. However, the amounts reported in rows 5, 7 and 9 herein represent the number of shares of Common Stock that would be issuable upon full exercise of the Enrollment Warrants and the Data Release Warrants into Series B Preferred Stock and the full conversion of Series B Preferred Stock to shares of Common Stock, without giving effect to the blocking provisions.
SCHEDULE 13G
CUSIP Number(s):
78397T202
1
Names of Reporting Persons
Vivo Opportunity Cayman Fund, L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
CAYMAN ISLANDS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
2,286,301.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
2,286,301.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,286,301.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.99 %
12
Type of Reporting Person (See Instructions)
PN
Comment for Type of Reporting Person: The reported share amount represents an aggregate of (i) 667,401 shares of Common Stock of the Issuer, (ii) 47,500 shares of Common Stock issuable upon conversion of 475 shares of the Issuer's Series B Preferred Stock, convertible within 60 days of this Statement, (iii) 1,047,600 shares of Common Stock issuable upon conversion of 10,476 shares of Series B Preferred Stock underlying 10,476 Enrollment Warrants that are exercisable within 60 days of this Statement, and (iv) 523,800 shares of Common Stock issuable upon conversion of 5,238 shares of Series B Preferred Stock underlying 5,238 Data Release Warrants that are exercisable within 60 days of this Statement. All securities are held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P.
The Series B Preferred Stock, the Enrollment Warrants and the Data Release Warrant all contain provisions preventing these securities from being converted or exercised into shares of Common Stock, if such conversion or exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities. However, the amounts reported in rows 5, 7 and 9 herein represent the number of shares of Common Stock that would be issuable upon full exercise of the Enrollment Warrants and the Data Release Warrants into Series B Preferred Stock and the full conversion of Series B Preferred Stock to shares of Common Stock, without giving effect to the blocking provisions.
SCHEDULE 13G
CUSIP Number(s):
78397T202
1
Names of Reporting Persons
Vivo Opportunity Cayman, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
CAYMAN ISLANDS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
2,286,301.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
2,286,301.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,286,301.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.99 %
12
Type of Reporting Person (See Instructions)
OO
Comment for Type of Reporting Person: The reported share amount represents an aggregate of (i) 667,401 shares of Common Stock of the Issuer, (ii) 47,500 shares of Common Stock issuable upon conversion of 475 shares of the Issuer's Series B Preferred Stock, convertible within 60 days of this Statement, (iii) 1,047,600 shares of Common Stock issuable upon conversion of 10,476 shares of Series B Preferred Stock underlying 10,476 Enrollment Warrants that are exercisable within 60 days of this Statement, and (iv) 523,800 shares of Common Stock issuable upon conversion of 5,238 shares of Series B Preferred Stock underlying 5,238 Data Release Warrants that are exercisable within 60 days of this Statement. All securities are held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P.
The Series B Preferred Stock, the Enrollment Warrants and the Data Release Warrant all contain provisions preventing these securities from being converted or exercised into shares of Common Stock, if such conversion or exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities. However, the amounts reported in rows 5, 7 and 9 herein represent the number of shares of Common Stock that would be issuable upon full exercise of the Enrollment Warrants and the Data Release Warrants into Series B Preferred Stock and the full conversion of Series B Preferred Stock to shares of Common Stock, without giving effect to the blocking provisions.
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
SAB Biotherapeutics, Inc.
(b)
Address of issuer's principal executive offices:
777 W 41st St, Suite 401, Miami Beach, FL 33140
Item 2.
(a)
Name of person filing:
Vivo Opportunity Fund Holdings, L.P. and its General Partner Vivo Opportunity, LLC
Vivo Opportunity Cayman Fund, L.P. and its General Partner Vivo Opportunity Cayman, LLC
(b)
Address or principal business office or, if none, residence:
192 Lytton Avenue, Palo Alto, CA 94301
(c)
Citizenship:
Vivo Opportunity Fund Holdings, L.P. is a Delaware limited partnership.
Vivo Opportunity, LLC is a Delaware limited liability company.
Vivo Opportunity Cayman Fund, L.P. is a Cayman Islands limited partnership.
Vivo Opportunity Cayman, LLC is a Cayman Islands limited liability company.
(d)
Title of class of securities:
Common Stock, par value $0.0001 per share
(e)
CUSIP No.:
78397T202
Item 4.
Ownership
(a)
Amount beneficially owned:
Vivo Opportunity, LLC may be deemed to beneficially own an aggregate of 22,637,108 shares of the Issuer's securities, consisting of (i) 6,632,508 shares of Common Stock of the Issuer, (ii) 446,000 shares of Common Stock issuable upon conversion of 4,460 shares of the Issuer's Series B Preferred Stock, convertible within 60 days of this Statement, (iii) 10,372,400 shares of Common Stock issuable upon conversion of 103,724 shares of Series B Preferred Stock underlying 103,724 Enrollment Warrants that are exercisable within 60 days of this Statement, and (iv) 5,186,200 shares of Common Stock issuable upon conversion of 51,862 shares of Series B Preferred Stock underlying 51,862 Data Release Warrants that are exercisable within 60 days of this Statement. The securities are held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P.
Vivo Opportunity Cayman, LLC may be deemed to beneficially own an aggregate of 2,286,301 shares of the Issuer's securities, consisting of (i) 667,401 shares of Common Stock of the Issuer, (ii) 47,500 shares of Common Stock issuable upon conversion of 475 shares of the Issuer's Series B Preferred Stock, convertible within 60 days of this Statement, (iii) 1,047,600 shares of Common Stock issuable upon conversion of 10,476 shares of Series B Preferred Stock underlying 10,476 Enrollment Warrants that are exercisable within 60 days of this Statement, and (iv) 523,800 shares of Common Stock issuable upon conversion of 5,238 shares of Series B Preferred Stock underlying 5,238 Data Release Warrants that are exercisable within 60 days of this Statement. These securities are held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P.
The Series B Preferred Stock, the Enrollment Warrants and the Data Release Warrant all contain provisions preventing these securities from being converted or exercised into shares of Common Stock, if such conversion or exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities. However, the amounts reported in this Item 4 herein represent the number of shares of Common Stock that would be issuable upon full exercise of the Enrollment Warrants and the Data Release Warrants into Series B Preferred Stock and the full conversion of Series B Preferred Stock to shares of Common Stock, without giving effect to the blocking provisions.
(b)
Percent of class:
Vivo Opportunity Fund Holdings, L.P.: 9.99%
Vivo Opportunity, LLC: 9.99%
Vivo Opportunity Cayman Fund, L.P.: 9.99%
Vivo Opportunity Cayman, LLC: 9.99%
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
Vivo Opportunity Fund Holdings, L.P.: 22,637,108 shares
Vivo Opportunity, LLC: 22,637,108 shares
Vivo Opportunity Cayman Fund, L.P.: 2,286,301 shares
Vivo Opportunity Cayman, LLC: 2,286,301 shares
(ii) Shared power to vote or to direct the vote:
0
(iii) Sole power to dispose or to direct the disposition of:
Vivo Opportunity Fund Holdings, L.P.: 22,637,108 shares
Vivo Opportunity, LLC: 22,637,108 shares
Vivo Opportunity Cayman Fund, L.P.: 2,286,301 shares
Vivo Opportunity Cayman, LLC: 2,286,301 shares
(iv) Shared power to dispose or to direct the disposition of:
0
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Vivo Opportunity Fund Holdings, L.P.
Signature:
/s/ Kevin Dai
Name/Title:
Kevin Dai/Managing Member of Vivo Opportunity, LLC, General Partner
Date:
08/14/2026
Vivo Opportunity, LLC
Signature:
/s/ Kevin Dai
Name/Title:
Kevin Dai/Managing Member
Date:
08/14/2026
Vivo Opportunity Cayman Fund, L.P.
Signature:
/s/ Kevin Dai
Name/Title:
Kevin Dai/Managing Member of Vivo Opportunity Cayman, LLC, General Partner