[Form 3] Shuttle Pharmaceuticals Holdings, Inc. Initial Statement of Beneficial Ownership

Rhea-AI Filing Summary

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) filed an initial Form 3 reporting that Adam V. Chambers is a director as of 09/08/2025. The filing lists Mr. Chambers' business address in Gaithersburg, MD and indicates he directly beneficially owns 0 shares of the issuer's common stock and holds no derivative securities. The form is an initial disclosure of a director's ownership and contains no reported holdings or exercisable awards.

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person^*

Chambers Adam V

(Last) (First) (Middle)

C/O SHUTTLE PHARMACEUTICALS HOLDINGS

401 PROFESSIONAL DRIVE, SUITE 260

(Street)

GAITHERSBURG MD 20879

(City) (State) (Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
09/08/2025

3. Issuer Name and Ticker or Trading Symbol
Shuttle Pharmaceuticals Holdings, Inc. [ SHPH ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
COMMON STOCK	0	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

	/s/ Adam Chambers	09/08/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What does the SHPH Form 3 filed for Adam V. Chambers disclose?

The filing discloses that Adam V. Chambers is a director and directly owns 0 shares of Shuttle Pharmaceuticals Holdings common stock as of 09/08/2025.

Does the Form 3 for SHPH show any derivative securities for Adam Chambers?

No. The Form 3 reports no derivative securities beneficially owned by Mr. Chambers.

Is this Form 3 an initial filing or an amendment for SHPH?

This is an initial Form 3 filing reporting the director's beneficial ownership; no amendment date is provided.

What address is listed for the reporting person on the SHPH Form 3?

The form lists the reporting person at 401 Professional Drive, Suite 260, Gaithersburg, MD 20879 (c/o Shuttle Pharmaceuticals Holdings).

Does the Form 3 indicate joint filing or multiple reporting persons?

No. The form indicates it was filed by one reporting person.