HRT FINANCIAL LP increases Shuttle (SHPH) stake with open-market share purchase

Rhea-AI Filing Summary

HRT FINANCIAL LP, a ten percent owner of Shuttle Pharmaceuticals Holdings, Inc., reported an open-market purchase of common stock. On July 1, 2026, it bought 3,959 shares of Shuttle common stock at $3.30 per share. After this transaction, HRT FINANCIAL LP directly owns 82,556 shares of Shuttle common stock.

Insider Trade Summary

Net Buyer: 3,959 shares ($13,065)

Net Buy 1 txn

Insider HRT FINANCIAL LP

Role null

Bought 3,959 shs ($13K)

Type	Security	Shares	Price	Value
Purchase	Common Stock	3,959	$3.30	$13K

Holdings After Transaction: Common Stock — 82,556 shares (Direct, null)

Footnotes (1)

Key Figures

Shares purchased: 3,959 shares Purchase price: $3.30 per share Shares owned after: 82,556 shares +2 more

5 metrics

Shares purchased 3,959 shares Open-market purchase of Shuttle common stock on July 1, 2026

Purchase price $3.30 per share Price paid by HRT FINANCIAL LP for SHPH common stock

Shares owned after 82,556 shares Direct SHPH common stock holdings following the transaction

Buy transactions 1 transaction Form 4 transaction summary net-buy activity

Net buy shares 3,959 shares Net change from buy/sell activity reported in this Form 4

Key Terms

ten percent owner, open-market purchase, Form 4, Common Stock

4 terms

ten percent owner regulatory

"HRT FINANCIAL LP is marked as a ten percent owner of the issuer."

open-market purchase financial

"The transaction_action field describes an open-market purchase of common stock."

An open-market purchase is when an investor or a company buys shares on a public stock exchange at the going market price, rather than through a private deal. It matters to investors because these purchases change how many shares are available, can push the stock price up or signal confidence from large buyers, and often affect per-share metrics like earnings—think of it like someone buying lots of apples off a grocery shelf, reducing supply and potentially raising the price.

Form 4 regulatory

"Insider transaction data is reported on a Form 4 for this issuer."

Form 4 is a official document that company insiders, such as executives or major shareholders, file with regulators whenever they buy or sell company shares. It provides transparency about how those with inside knowledge are trading, helping investors see if insiders are confident in the company's prospects or may be selling for personal reasons. This information can influence investor decisions by revealing insiders' perspectives on the company's value.

Common Stock financial

"The security_title for the transaction is listed as Common Stock."

Common stock represents ownership shares in a company, giving investors a stake in its success and a say in important decisions through voting rights. It is the most common type of stock traded on markets and can provide income through dividends, as well as potential for value growth. For investors, holding common stock means sharing in the company’s profits and risks.

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Form 4 Insider Transactions: What Each Field Means →

Available on EDGAR 07/02/2026 - 01:38 PM Accepted by SEC EDGAR 07/02/2026 - 01:37 PM Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

HRT FINANCIAL LP

(Last) (First) (Middle)

3 WORLD TRADE CENTER, 175 GREENWICH STRE

76TH FLOOR

(Street)

NEW YORK NEW YORK 10007

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Shuttle Pharmaceuticals Holdings, Inc. [ SHPH ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
06/29/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	07/01/2026		P		3,959	A	$3.3	82,556	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

	Adam Nunes	07/02/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transaction did HRT FINANCIAL LP report for SHPH?

HRT FINANCIAL LP reported an open-market purchase of 3,959 shares of Shuttle Pharmaceuticals common stock at $3.30 per share. This transaction was disclosed on a Form 4 as a direct ownership change for this ten percent owner.

How many SHPH shares does HRT FINANCIAL LP own after this Form 4?

After the reported purchase, HRT FINANCIAL LP directly owns 82,556 shares of Shuttle Pharmaceuticals common stock. This total reflects the addition of 3,959 shares bought on July 1, 2026, at a price of $3.30 per share.

Was the SHPH transaction by HRT FINANCIAL LP a buy or a sell?

The transaction was a buy. HRT FINANCIAL LP executed an open-market purchase of 3,959 shares of Shuttle Pharmaceuticals common stock at $3.30 per share, increasing its directly held position to 82,556 shares according to the Form 4.

What is the significance of HRT FINANCIAL LP as a ten percent owner of SHPH?

HRT FINANCIAL LP is classified as a ten percent owner of Shuttle Pharmaceuticals, making it a large shareholder subject to Form 4 reporting. Its July 1, 2026 open-market purchase of 3,959 shares at $3.30 per share reflects changes in a sizable position.

What type of security did HRT FINANCIAL LP purchase in Shuttle Pharmaceuticals?

HRT FINANCIAL LP purchased common stock of Shuttle Pharmaceuticals. The Form 4 shows an open-market purchase of 3,959 common shares at $3.30 per share on July 1, 2026, bringing its directly held common stock position to 82,556 shares.