Welcome to our dedicated page for Syndax Pharmaceuticals SEC filings (Ticker: SNDX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Tracking the science is hard enough—decoding the disclosures behind it can feel impossible. Syndax Pharmaceuticals’ 10-K often buries trial outcomes for revumenib and axatilimab deep inside 200-plus pages, while surprise 8-K updates surface new royalty deals overnight. If you have ever asked, “Where can I find the Syndax Pharmaceuticals quarterly earnings report 10-Q filing?” or searched for “Syndax Pharmaceuticals insider trading Form 4 transactions,” you already know the challenge.
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Michael A. Metzger, the Chief Executive Officer and a director of Syndax Pharmaceuticals, Inc. (SNDX), reported option exercise and an immediate sale on 09/08/2025. He exercised 157,307 options at an exercise price of $10.90 to acquire 157,307 shares and then sold the same 157,307 shares under a Rule 10b5-1 plan at prices ranging from $16.21 to $17.06. The filings show beneficial ownership figures of 455,968 shares after the exercise and 298,661 shares after the sale. The report states Metzger has 1,319,634 vested options immediately exercisable and 651,241 unvested options remaining. The option exercised was fully vested.
Syndax Pharmaceuticals (SNDX) reported a Notice of Proposed Sale on Form 144 indicating an intended sale of 157,307 common shares through Morgan Stanley Smith Barney (NASDAQ) with an aggregate market value of $2,680,511.28, and an approximate sale date of 09/08/2025. The shares were acquired on 09/08/2025 by exercise of stock options from the issuer, with payment in cash. The filing also discloses a prior sale by Michael Metzger of 7,534 shares on 07/16/2025 for $69,953.19. The filer certifies no undisclosed material adverse information.
Dennis Podlesak, a director of Syndax Pharmaceuticals, reported option exercises and planned sales under a Rule 10b5-1 plan in mid-August 2025. On 08/14/2025, 08/15/2025 and 08/18/2025 he exercised options with a $7.20 strike to acquire blocks of 19,200, 19,200 and 19,200 shares respectively, and contemporaneously reported sales of those shares under the 10b5-1 plan at prices that ranged across the transactions: $13.30–$16.00 (detailed ranges per date provided). Following the reported transactions the Form 4 shows 210,963 shares beneficially owned after acquisitions and 191,763 after sales, and the filer notes he holds 135,000 vested, exercisable options remaining.
Point72 entities and Steven A. Cohen report a 5.0% stake in Syndax Pharmaceuticals (SNDX). As of the close of business on August 15, 2025, Point72 Asset Management, L.P., Point72 Capital Advisors, Inc. and Steven A. Cohen each report beneficial ownership of 4,327,952 shares of Syndax common stock, representing 5.0% of the class. The filing shows no sole voting or dispositive power and reports shared voting and shared dispositive power of 4,327,952 shares. The statement is filed jointly pursuant to a Joint Filing Agreement (Exhibit 99.1). The issuer's principal executive office is listed at 730 Third Avenue, 9th Floor, New York, NY 10017.
Syndax Pharmaceuticals (SNDX) Form 144 notice reports a proposed sale of 14,400 common shares through Morgan Stanley Smith Barney on NASDAQ, with an aggregate market value of $226,656. The securities were acquired by exercise of stock options on 08/18/2025 and payment was in cash the same day. The filing also discloses two recent Rule 10b5-1 sales by Dennis G. Podlesak in mid-August totaling 38,400 shares for gross proceeds of $570,928.80 ($298,408.32 and $272,520.48). The signee certifies no undisclosed material adverse information and notes any applicable 10b5-1 plan adoption where relevant.
Syndax Pharmaceuticals Schedule 13G/A shows that Point72-related entities and Steven A. Cohen report shared beneficial ownership of 2,307,824 shares of Syndax common stock, representing 2.7% of the class as of the close of business on June 30, 2025. The filing states Point72 Asset Management exercises shared voting and dispositive power over these shares on behalf of an investment fund it manages; Point72 Capital Advisors is the general partner and Mr. Cohen controls both entities. The filing clarifies the position is not intended to indicate an attempt to influence control of the issuer.
Form 144 notice for SNDX reports a proposed sale of 43,200 shares of common stock through Morgan Stanley Smith Barney LLC on 08/14/2025, with an aggregate market value of $581,040.00. The shares were acquired the same day by exercise of stock options and paid for in cash. The filing lists 86,141,862 shares outstanding, and there are no reported sales by the same person in the prior three months.
The notice confirms the seller represents they have no undisclosed material adverse information and follows Rule 144 procedures for the proposed sale.
Schedule 13G/A filed for Syndax Pharmaceuticals, Inc. reports that The Goldman Sachs Group, Inc. and Goldman Sachs & Co. LLC jointly hold 5,581,828.06 shares of Syndax common stock, representing 6.5% of the class as reported for the event date 06/30/2025. The filing shows no sole voting or dispositive power and substantial shared voting power (5,581,718.06) and shared dispositive power (5,581,828.06). The cover exhibits include a joint filing agreement and identification of Goldman Sachs & Co. LLC as a subsidiary of GS Group. The registrants certify the securities are held in the ordinary course of business and not for the purpose of changing control.
Syndax Pharmaceuticals (SNDX) – Form 4 insider activity: Chief Financial Officer Keith A. Goldan purchased 1,226 common shares on 07/31/2025 under the company’s Employee Stock Purchase Plan (ESPP) at an average price of $8.43 per share. The transaction is coded “J,” confirming it is part of a tax-qualified plan rather than an open-market buy.
Following the purchase, Goldan’s direct ownership rises to 93,676 shares. No derivative securities were reported. The filing was submitted on 08/07/2025 and signed by attorney-in-fact Michael A. Metzger.
The acquisition is modest in dollar terms (≈$10 k) but represents incremental insider buying, which can be interpreted as a signal of management confidence. However, the size relative to Goldan’s total stake and SNDX’s share count suggests limited market impact.
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