Senti Biosciences withholds 19,953 shares for taxes

The reported withholding satisfied tax obligations tied to net settlement of certain time-based restricted stock unit awards, not an open-market sale.

Rhea-AI Filing Summary

Senti Biosciences Holdings, Inc. (SNTI) reported that 19,953 common shares were withheld by the issuer from Kanya Rajangam, the issuer’s Pres. & Chief Med. & Dev. Off., on October 21, 2026, to satisfy income tax withholding and remittance obligations tied to net settlement of certain time-based restricted stock unit awards. The withholding was not an open-market sale. Rajangam directly held 54,890 common shares following the transaction.

Insider Trade Summary

Tax Withholding: 19,953 shares

Tax Withholding 1 txn

Insider Rajangam Kanya

Role Pres. & Chief Med. & Dev. Off.

Type	Security	Shares	Price	Value
Tax Withholding	Common Stock F1	19,953	$0.00	$0.00

Holdings After Transaction: Common Stock — 54,890 shares (Direct)

Footnotes (1)

1. F1. Represents the number of shares of common stock that have been withheld by the Issuer to satisfy its income tax withholding and remittance obligations in connection with the net settlement of certain time-based restricted stock unit awards and does not represent an open market sale.

Key Figures

Common shares withheld: 19,953 shares Direct common shares following transaction: 54,890 shares

2 metrics

Common shares withheld 19,953 shares October 21, 2026; withheld for income tax obligations tied to RSU net settlement

Direct common shares following transaction 54,890 shares Following the October 21, 2026 transaction

Key Terms

net settlement, time-based restricted stock unit awards, income tax withholding and remittance obligations

3 terms

net settlement financial

"in connection with the net settlement of certain time-based restricted stock unit awards"

time-based restricted stock unit awards financial

"net settlement of certain time-based restricted stock unit awards"

income tax withholding and remittance obligations financial

"to satisfy its income tax withholding and remittance obligations"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many SNTI shares were withheld for Kanya Rajangam’s taxes?

19,953 common shares were withheld by the issuer on October 21, 2026, to satisfy income tax withholding and remittance obligations tied to net settlement of certain time-based restricted stock unit awards.

How many SNTI shares did Kanya Rajangam hold after the withholding?

Rajangam directly held 54,890 common shares following the October 21, 2026 transaction.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 10/23/2026 - 04:38 PM EDT Accepted by SEC EDGAR 10/23/2026 - 04:38 PM EDT Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

X

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Rajangam Kanya

(Last) (First) (Middle)

C/O SENTI BIOSCIENCES, INC.

2 CORPORATE DRIVE FIRST FLOOR

(Street)

SOUTH SAN FRANCISCO CALIFORNIA 94080

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Senti Biosciences Holdings, Inc. [ SNTI ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Pres. & Chief Med. & Dev. Off.

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
10/21/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	10/21/2026		F		19,953(1)	D	$0	54,890	D(1)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Represents the number of shares of common stock that have been withheld by the Issuer to satisfy its income tax withholding and remittance obligations in connection with the net settlement of certain time-based restricted stock unit awards and does not represent an open market sale.

Remarks:

	/s/ Robert Cutler, attorney-in-fact	10/22/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)