Senti Biosciences Holdings, Inc. (SNTI) reported $22K in revenue for fiscal year 2025. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 5 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).
Senti remains a cash-burning development-stage platform, where research spending and financing matter far more than reported revenue.
From FY2023 to FY2025, operating cash burn improved only modestly, from-$52.4M to-$43.4M , so the cost base remained largely intact despite almost no commercial revenue. Because cash is now$16.4M and equity only$5.6M , new financing appears to be extending runway rather than building a self-funding business.
FY2025 reads like a pre-commercial cost structure: revenue was only
The liquidity cushion has narrowed as cash fell from
Financial Health Signals
Senti Biosciences Holdings, Inc. does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.
Senti Biosciences Holdings, Inc. scores -13.86, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($11.8M) relative to total liabilities ($45.6M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.
Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.
Senti Biosciences Holdings, Inc. passes 2 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), both operating efficiency signals pass.
Senti Biosciences Holdings, Inc. reported a net loss of $61.4M while operations used $43.4M of cash. With neither figure positive, the ratio between the two carries no quality signal.
Key Financial Metrics
Earnings & Revenue
Senti Biosciences Holdings, Inc. generated $22K in revenue in fiscal year 2025.
Senti Biosciences Holdings, Inc.'s EBITDA was -$65.1M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 13.9% from the prior year.
Senti Biosciences Holdings, Inc. reported -$61.4M in net income in fiscal year 2025. This represents a decrease of 16.4% from the prior year.
Senti Biosciences Holdings, Inc. earned -$2.73 per diluted share (EPS) in fiscal year 2025.
Cash & Balance Sheet
Senti Biosciences Holdings, Inc. recorded an outflow of $43.6M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents a decrease of 5.4% from the prior year.
Senti Biosciences Holdings, Inc. held $16.4M in cash as of fiscal year 2025; long-term debt is not reported for that period.
Not reported for fiscal year 2025.
Margins & Returns
Senti Biosciences Holdings, Inc.'s ROE was -1099.3% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is down 893.5 percentage points from the prior year.
Not reported for fiscal year 2025.
Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.
Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.
Capital Allocation
Senti Biosciences Holdings, Inc. invested $37.6M in research and development in fiscal year 2025. This represents an increase of 9.4% from the prior year.
Senti Biosciences Holdings, Inc. invested $196K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 653.8% from the prior year.
Not reported for fiscal year 2025.
SNTI Income Statement
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.
| Metric | Q2'26 | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $17K+6.3% | $16K | N/A | N/A | $0 | $0 | N/A | $0 |
| R&D Expenses | $7.8M+47.1% | $5.3M | N/A | $10.5M+4.9% | $10.0M+8.1% | $9.3M | N/A | $8.7M |
| SG&A Expenses | $6.7M+8.1% | $6.2M | N/A | $6.4M-5.0% | $6.8M-4.9% | $7.1M | N/A | $6.6M |
| Operating Income | -$14.5M-213.9% | -$4.6M | N/A | -$16.9M-0.9% | -$16.8M-2.4% | -$16.4M | N/A | -$15.2M |
| Income Tax | $0 | $0 | N/A | $0 | $0 | $0 | N/A | $0 |
| Net Income | -$12.8M-202.1% | -$4.2M | N/A | -$18.1M-23.0% | -$14.7M-4.4% | -$14.1M | N/A | -$28.9M |
| EPS (Diluted) | -$0.41-192.9% | -$0.14+70.8% | -$0.48+30.4% | -$0.69-23.2% | -$0.56 | -$1.41-127.4% | -$0.62 | -$6.31 |
Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, Interest Expense.
SNTI Balance Sheet
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.
| Metric | Q2'26 | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 |
|---|---|---|---|---|---|---|---|---|
| Total Assets | $33.1M-13.4% | $38.2M-25.3% | $51.2M-2.8% | $52.7M-23.1% | $68.5M-17.2% | $82.8M-15.4% | $97.8M+69.5% | $57.7M |
| Current Assets | $13.0M-12.1% | $14.8M-36.5% | $23.3M+28.2% | $18.2M-44.2% | $32.5M-28.1% | $45.2M-23.3% | $59.0M+239.2% | $17.4M |
| Cash & Equivalents | $6.5M-27.7% | $8.9M-45.6% | $16.4M+34.1% | $12.2M-43.3% | $21.6M-36.2% | $33.8M-30.0% | $48.3M+360.7% | $10.5M |
| Total Liabilities | $36.5M+2.3% | $35.7M-21.8% | $45.6M+2.4% | $44.6M+1.5% | $43.9M-2.3% | $44.9M-37.8% | $72.2M+73.0% | $41.7M |
| Current Liabilities | $15.8M+10.5% | $14.3M+2.1% | $14.0M+16.2% | $12.0M+20.4% | $10.0M-6.9% | $10.7M-18.4% | $13.1M+45.0% | $9.1M |
| Total Equity | -$3.4M-232.6% | $2.6M-54.1% | $5.6M-31.2% | $8.1M-67.1% | $24.7M-34.9% | $37.9M+47.6% | $25.6M+60.4% | $16.0M |
| Retained Earnings | -$375.5M-3.5% | -$362.8M-1.2% | -$358.6M-4.2% | -$344.1M-5.6% | -$326.0M-4.7% | -$311.2M-4.7% | -$297.1M-0.2% | -$296.5M |
Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.
SNTI Cash Flow Statement
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.
| Metric | Q2'26 | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 |
|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | -$14.2M-90.5% | -$7.5M-8.8% | -$6.9M+27.2% | -$9.4M+27.7% | -$13.1M+7.0% | -$14.1M-4.0% | -$13.5M-71.7% | -$7.9M |
| Capital Expenditures | N/A | N/A | $0 | $0-100.0% | $196K | $0-100.0% | $11K | $0 |
| Free Cash Flow | N/A | N/A | -$6.9M+27.2% | -$9.4M+28.8% | -$13.3M+5.6% | -$14.1M-4.0% | -$13.5M-71.8% | -$7.9M |
| Investing Cash Flow | $0-100.0% | $114K | $0 | $0+100.0% | -$184K | $0+100.0% | -$11K-118.3% | $60K |
| Financing Cash Flow | $9.7M+8299.2% | -$118K-101.1% | $11.0M+8803.2% | $124K-87.7% | $1.0M+344.2% | -$414K-100.8% | $51.3M+2002.0% | $2.4M |
Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.
SNTI Financial Ratios
Margins and returns are percentages; the remaining ratios are unitless multiples.
| Metric | Q2'26 | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 |
|---|---|---|---|---|---|---|---|---|
| Operating Margin | -85229.4% | -28850.0% | N/A | N/A | N/A | N/A | N/A | N/A |
| Net Margin | -75000.0% | -26381.3% | N/A | N/A | N/A | N/A | N/A | N/A |
| Return on Equity | N/A | -164.6% | N/A | -223.2%-163.4pp | -59.8%-22.5pp | -37.3% | N/A | -180.5% |
| Return on Assets | -38.5%-27.5pp | -11.0% | N/A | -34.4%-12.9pp | -21.5%-4.4pp | -17.1% | N/A | -50.0% |
| Current Ratio | 0.83-0.2x | 1.04-0.6x | 1.67+0.2x | 1.51-1.7x | 3.26-1.0x | 4.22-0.3x | 4.49+2.6x | 1.92 |
| Debt-to-Equity | N/A | 13.91+5.7x | 8.16+2.7x | 5.49+3.7x | 1.78+0.6x | 1.19-1.6x | 2.81+0.2x | 2.61 |
Not reported in any period shown, so not listed: Gross Margin, FCF Margin.
Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin.
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Where Senti Biosciences Holdings, Inc. Ranks
Frequently Asked Questions
What is Senti Biosciences Holdings, Inc.'s annual revenue?
Senti Biosciences Holdings, Inc. (SNTI) reported $22K in total revenue for fiscal year 2025. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.
Is Senti Biosciences Holdings, Inc. profitable?
No, Senti Biosciences Holdings, Inc. (SNTI) reported a net income of -$61.4M in fiscal year 2025.
What is Senti Biosciences Holdings, Inc.'s EBITDA?
Senti Biosciences Holdings, Inc. (SNTI) had EBITDA of -$65.1M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.
What is Senti Biosciences Holdings, Inc.'s return on equity (ROE)?
Senti Biosciences Holdings, Inc. (SNTI) has a return on equity of -1099.3% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.
What is Senti Biosciences Holdings, Inc.'s free cash flow?
Senti Biosciences Holdings, Inc. (SNTI) recorded an outflow of $43.6M in free cash flow during fiscal year 2025. This represents a -5.4% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.
What is Senti Biosciences Holdings, Inc.'s operating cash flow?
Senti Biosciences Holdings, Inc. (SNTI) recorded an outflow of $43.4M in operating cash flow during fiscal year 2025, representing cash used by core business activities.
What are Senti Biosciences Holdings, Inc.'s total assets?
Senti Biosciences Holdings, Inc. (SNTI) had $51.2M in total assets as of fiscal year 2025, including both current and long-term assets.
What are Senti Biosciences Holdings, Inc.'s capital expenditures?
Senti Biosciences Holdings, Inc. (SNTI) invested $196K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.
How much does Senti Biosciences Holdings, Inc. spend on research and development?
Senti Biosciences Holdings, Inc. (SNTI) invested $37.6M in research and development during fiscal year 2025.
What is Senti Biosciences Holdings, Inc.'s current ratio?
Senti Biosciences Holdings, Inc. (SNTI) had a current ratio of 1.67 as of fiscal year 2025, which is generally considered healthy.
What is Senti Biosciences Holdings, Inc.'s debt-to-equity ratio?
Senti Biosciences Holdings, Inc. (SNTI) had a debt-to-equity ratio of 8.16 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.
What is Senti Biosciences Holdings, Inc.'s return on assets (ROA)?
Senti Biosciences Holdings, Inc. (SNTI) had a return on assets of -119.9% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.
How does Senti Biosciences Holdings, Inc.'s liquidity compare with its operating cash outflow?
At the end of fiscal year 2025, Senti Biosciences Holdings, Inc. (SNTI) held $16.4M in cash, cash equivalents and investments, and reported an operating cash outflow of $43.4M over that year. Dividing the one by the other, the reported balance equals about 5 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.
What is Senti Biosciences Holdings, Inc.'s Altman Z-Score?
Senti Biosciences Holdings, Inc. (SNTI) has an Altman Z-Score of -13.86, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.
What is Senti Biosciences Holdings, Inc.'s Piotroski F-Score?
Senti Biosciences Holdings, Inc. (SNTI) has a Piotroski F-Score of 2 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.
Are Senti Biosciences Holdings, Inc.'s earnings high quality?
Senti Biosciences Holdings, Inc. (SNTI) reported a net loss of $61.4M while operations used $43.4M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.