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ARCH Venture entities detail Seaport Therapeutics (SPTX) convertible preferred holdings

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
3

Rhea-AI Filing Summary

Seaport Therapeutics, Inc. reports ARCH-affiliated initial holdings in preferred stock that is convertible into common shares. ARCH Venture Fund XII, L.P. holds Series B Preferred Stock representing 2,681,265 underlying shares of Common Stock and Series A-2 Preferred Stock representing 2,513,686 underlying shares, all as indirect ownership.

Each share of Series A-2 Preferred Stock and Series B Preferred Stock is convertible into Common Stock on a one-for-3.1407 basis at the option of the holder and will automatically convert into the stated numbers of common shares upon the closing of the company’s initial public offering, with no additional consideration and no expiration date. The structure runs through ARCH Venture Partners XII, L.P. and ARCH Venture Partners XII, LLC, and investment committee members Keith Crandell, Kristina Burow, Steven Gillis and Robert Nelsen disclaim beneficial ownership beyond any pecuniary interest.

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Insider ARCH Venture Partners XII, LLC, ARCH Venture Partners XII, L.P., ARCH Venture Fund XII, L.P., CRANDELL KEITH, NELSEN ROBERT, Burow Kristina, GILLIS STEVEN
Role null | null | null | null | null | null | null
Type Security Shares Price Value
holding Series A-2 Preferred Stock -- -- --
holding Series B Preferred Stock -- -- --
Holdings After Transaction: Series A-2 Preferred Stock — 2,513,686 shares (Indirect, By ARCH Venture Fund XII, L.P.); Series B Preferred Stock — 2,681,265 shares (Indirect, By ARCH Venture Fund XII, L.P.)
Footnotes (1)
  1. Each share of Series A-2 Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") is convertible into Common Stock of the Issuer on a one-for-3.1407 basis at the option of the holder, and will automatically convert upon the closing of the Issuer's initial public offering into the number of shares shown in Column 3 without payment of further consideration. The Preferred Stock has no expiration date. Shares held directly by ARCH Venture Fund XII, L.P. ("ARCH XII"). ARCH Venture Partners XII, L.P. ("AVP XII LP") is the sole general partner of ARCH XII. ARCH Venture Partners XII, LLC ("AVP XII LLC") is the sole general partner of AVP XII LP. Keith Crandell, Kristina Burow, Steven Gillis and Robert Nelsen are members of the investment committee of AVP XII LLC (the "AVP XII LLC Committee Members"). Each of AVP XII LP and AVP XII LLC may be deemed to beneficially own the shares held by ARCH XII, and each of the AVP XII LLC Committee Members may be deemed to share the power to direct the disposition and vote of the shares held by ARCH XII. Each of AVP XII LP, AVP XII LLC and the AVP XII LLC Committee Members disclaims beneficial ownership except to the extent of their pecuniary interest therein, if any.
Underlying common from Series B 2,681,265 shares Underlying Common Stock for Series B Preferred Stock, indirect holding
Underlying common from Series A-2 2,513,686 shares Underlying Common Stock for Series A-2 Preferred Stock, indirect holding
Conversion ratio one-for-3.1407 Each Preferred Stock share convertible into Common Stock
Exercise price $0.0000 per share Conversion or exercise price for Preferred Stock
Unknown transaction entries 2 entries Holding entries with unknown transaction code on Form 3
Series B Preferred Stock financial
"Each share of Series A-2 Preferred Stock and Series B Preferred Stock"
Series B preferred stock is a type of ownership share issued by a company that offers certain advantages over common stock, such as priority in receiving dividends or assets if the company is sold or liquidated. It is typically issued after an initial round of funding, making it a way for investors to support a company's growth while gaining some protections and benefits. This stock matters to investors because it often provides a more secure investment position with potential for future growth.
Series A-2 Preferred Stock financial
"Each share of Series A-2 Preferred Stock and Series B Preferred Stock"
Series A-2 preferred stock is a specific class of shares created during a funding round that gives its holders stronger financial protections and priority over common shareholders, such as getting paid first if the company is sold or winding down. Investors care because these shares behave like a hybrid between a loan and regular stock: they often offer fixed payouts or conversion rights and a better claim on assets, making them lower risk and shaping potential returns.
convertible into Common Stock financial
"is convertible into Common Stock of the Issuer on a one-for-3.1407 basis"
initial public offering financial
"will automatically convert upon the closing of the Issuer's initial public offering"
An initial public offering (IPO) is when a private company first sells its shares to the public and becomes a stock-listed company. It matters because it allows the company to raise money from a wide range of investors, helping it grow, while giving early shareholders a way to sell some of their ownership.
beneficially own financial
"may be deemed to beneficially own the shares held by ARCH XII"
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
pecuniary interest financial
"disclaims beneficial ownership except to the extent of their pecuniary interest therein"
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SEC Form 3
FORM 3UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0104
Estimated average burden
hours per response:0.5
1. Name and Address of Reporting Person*
ARCH Venture Partners XII, LLC

(Last)(First)(Middle)
8755 W. HIGGINS ROAD, SUITE 1025

(Street)
CHICAGO ILLINOIS 60631

(City)(State)(Zip)

UNITED STATES

(Country)
2. Date of Event Requiring Statement (Month/Day/Year)
04/30/2026
3. Issuer Name and Ticker or Trading Symbol
Seaport Therapeutics, Inc. [ SPTX ]
3a. Foreign Trading Symbol
5. If Amendment, Date of Original Filed (Month/Day/Year)
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
DirectorX10% Owner
Officer (give title below)Other (specify below)
6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
XForm filed by More than One Reporting Person
Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5)
Table II - Derivative Securities Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4) 2. Date Exercisable and Expiration Date (Month/Day/Year)3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 6. Nature of Indirect Beneficial Ownership (Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Series A-2 Preferred Stock (1) (1)Common Stock2,513,686(1)IBy ARCH Venture Fund XII, L.P.(2)
Series B Preferred Stock (1) (1)Common Stock2,681,265(1)IBy ARCH Venture Fund XII, L.P.(2)
1. Name and Address of Reporting Person*
ARCH Venture Partners XII, LLC

(Last)(First)(Middle)
8755 W. HIGGINS ROAD, SUITE 1025

(Street)
CHICAGO ILLINOIS 60631

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
DirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
ARCH Venture Partners XII, L.P.

(Last)(First)(Middle)
8755 W. HIGGINS ROAD, SUITE 1025

(Street)
CHICAGO ILLINOIS 60631

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
DirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
ARCH Venture Fund XII, L.P.

(Last)(First)(Middle)
8755 W. HIGGINS ROAD, SUITE 1025

(Street)
CHICAGO ILLINOIS 60631

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
DirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
CRANDELL KEITH

(Last)(First)(Middle)
8755 W. HIGGINS ROAD, SUITE 1025

(Street)
CHICAGO ILLINOIS 60631

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
DirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
NELSEN ROBERT

(Last)(First)(Middle)
8755 W. HIGGINS ROAD, SUITE 1025

(Street)
CHICAGO ILLINOIS 60631

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
DirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
Burow Kristina

(Last)(First)(Middle)
8755 W. HIGGINS ROAD, SUITE 1025

(Street)
CHICAGO ILLINOIS 60631

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
DirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
GILLIS STEVEN

(Last)(First)(Middle)
8755 W. HIGGINS ROAD, SUITE 1025

(Street)
CHICAGO ILLINOIS 60631

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
DirectorX10% Owner
Officer (give title below)Other (specify below)
Explanation of Responses:
1. Each share of Series A-2 Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") is convertible into Common Stock of the Issuer on a one-for-3.1407 basis at the option of the holder, and will automatically convert upon the closing of the Issuer's initial public offering into the number of shares shown in Column 3 without payment of further consideration. The Preferred Stock has no expiration date.
2. Shares held directly by ARCH Venture Fund XII, L.P. ("ARCH XII"). ARCH Venture Partners XII, L.P. ("AVP XII LP") is the sole general partner of ARCH XII. ARCH Venture Partners XII, LLC ("AVP XII LLC") is the sole general partner of AVP XII LP. Keith Crandell, Kristina Burow, Steven Gillis and Robert Nelsen are members of the investment committee of AVP XII LLC (the "AVP XII LLC Committee Members"). Each of AVP XII LP and AVP XII LLC may be deemed to beneficially own the shares held by ARCH XII, and each of the AVP XII LLC Committee Members may be deemed to share the power to direct the disposition and vote of the shares held by ARCH XII. Each of AVP XII LP, AVP XII LLC and the AVP XII LLC Committee Members disclaims beneficial ownership except to the extent of their pecuniary interest therein, if any.
ARCH Venture Fund XII, L.P. By: ARCH Venture Partners XII, L.P., its General Partner By: ARCH Venture Partners XII, LLC, its General Partner By: /s/ Mark McDonnell, as Attorney-in-Fact04/30/2026
ARCH Venture Partners XII, L.P. By: ARCH Venture Partners XII, LLC, its General Partner By: /s/ Mark McDonnell, as Attorney-in-Fact04/30/2026
ARCH Venture Partners XII, LLC By: /s/ Mark McDonnell, as Attorney-in-Fact04/30/2026
/s/ Keith Crandell, By: Mark McDonnell, attorney-in-fact04/30/2026
/s/ Kristina Burow, By: Mark McDonnell, attorney-in-fact04/30/2026
/s/ Steven Gillis, By: Mark McDonnell, attorney-in-fact04/30/2026
/s/ Robert Nelsen, By: Mark McDonnell, attorney-in-fact04/30/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 3: SEC 1473 (03-26)

FAQ

What does the Seaport Therapeutics (SPTX) Form 3 filing by ARCH entities disclose?

The Form 3 shows initial indirect holdings of Seaport Therapeutics preferred stock by ARCH Venture Fund XII, L.P. These preferred shares are convertible into common stock and will automatically convert upon the company’s initial public offering, establishing ARCH’s baseline ownership position.

How many Seaport Therapeutics (SPTX) shares are linked to ARCH’s Series B Preferred Stock?

ARCH Venture Fund XII, L.P. holds Series B Preferred Stock convertible into 2,681,265 shares of Common Stock. These shares convert at a one-for-3.1407 ratio and will automatically convert into the reported number upon the closing of Seaport Therapeutics’ initial public offering.

How many Seaport Therapeutics (SPTX) shares are linked to ARCH’s Series A-2 Preferred Stock?

ARCH Venture Fund XII, L.P. holds Series A-2 Preferred Stock convertible into 2,513,686 shares of Common Stock. This preferred stock converts at the same one-for-3.1407 basis and will automatically convert into the stated common shares when Seaport Therapeutics completes its initial public offering.

What is the conversion feature of Seaport Therapeutics (SPTX) preferred stock held by ARCH?

Each share of Series A-2 and Series B Preferred Stock is convertible into common stock on a one-for-3.1407 basis. Conversion can occur at the holder’s option and will also automatically occur at IPO closing into the reported numbers of common shares without extra payment.

How is beneficial ownership of Seaport Therapeutics (SPTX) shares structured among ARCH entities?

Shares are held by ARCH Venture Fund XII, L.P., whose general partner is ARCH Venture Partners XII, L.P., with ARCH Venture Partners XII, LLC as general partner of that entity. Committee members Crandell, Burow, Gillis and Nelsen may be deemed to share power but disclaim beneficial ownership beyond pecuniary interest.

Do the Seaport Therapeutics (SPTX) preferred shares held by ARCH have an expiration date?

The filing states that the Seaport Therapeutics Preferred Stock has no expiration date. These preferred shares are convertible into common stock at a fixed one-for-3.1407 ratio, and they will automatically convert into common shares upon the closing of the company’s initial public offering.