Surrozen (SRZN) major holder The Column Group discloses stakes up to 29.3%

Rhea-AI Filing Summary

Surrozen, Inc. received an updated Schedule 13D/A from venture firm The Column Group and affiliated funds and managers detailing their stakes in the company’s common stock. The filing reports that various Column Group entities and principals Tim Kutzkey and Peter Svennilson collectively report significant beneficial ownership positions, calculated to include shares and warrants exercisable within 60 days.

The Column Group III GP LP reports beneficial ownership of 2,962,544 shares, or 23.6% of the class, while Kutzkey and Svennilson each report 3,824,612 shares, or 29.3%. These amounts reflect current holdings, rights to acquire shares in the second tranche of a private placement, and certain warrants that are exercisable within 60 days, and exclude additional warrants that cannot be exercised within that period due to beneficial ownership limitations.

Key Figures

TCG III GP LP ownership: 2,962,544 shares (23.6%) TCG III LP ownership: 1,391,340 shares (11.6%) TCG III-A LP ownership: 1,571,204 shares (13.0%) +4 more

7 metrics

TCG III GP LP ownership 2,962,544 shares (23.6%) Beneficially owned Surrozen common stock reported in Amendment No. 6

TCG III LP ownership 1,391,340 shares (11.6%) Includes shares and warrants exercisable within 60 days

TCG III-A LP ownership 1,571,204 shares (13.0%) Beneficially owned Surrozen common stock including near-term rights

TCG Opportunity III LP ownership 862,068 shares (7.2%) Based on shares held and rights to acquire within 60 days

Kutzkey and Svennilson ownership 3,824,612 shares (29.3%) Each reports this beneficial stake across Column Group vehicles

Shares outstanding base 11,486,707 shares Surrozen common stock outstanding as of March 19, 2026 per Form 10-K

Ownership denominator (Kutzkey/Svennilson) 13,049,542 shares Outstanding shares plus Column Group rights exercisable within 60 days

Key Terms

beneficial ownership, shared Voting Power, shared Dispositive Power, private placement transaction, +2 more

6 terms

beneficial ownership financial

"Each Reporting Person disclaims beneficial ownership of all securities reported in this Statement except to the extent of such Reporting Person's pecuniary interest"

Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

shared Voting Power financial

"Shared Voting Power 3,824,612.00"

Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.

shared Dispositive Power financial

"Shared Dispositive Power 2,962,544.00"

private placement transaction financial

"second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K"

warrants financial

"warrants to purchase 5,218 shares of Common Stock held by TCG III LP which are exercisable within 60 days of this Statement"

Warrants are special documents that give you the right to buy a company's stock at a set price before a certain date. They are often used as a way for companies to attract investors or raise money, and their value can increase if the company's stock price goes up.

beneficial ownership limitations financial

"warrants ... which are not exercisable within 60 days of this Statement due to beneficial ownership limitations"

Beneficial ownership limitations are rules or contractual caps that restrict how much of a company’s stock an individual or entity can be treated as owning or controlling for legal, regulatory or corporate-governance purposes. They matter to investors because such limits affect voting power, reporting obligations, takeover risk and the ability to increase a stake — like an elevator weight limit or a lane divider that prevents any one car from taking over the whole road.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934

(Amendment No. 6)

Surrozen, Inc.

(Name of Issuer)

Common Stock, $0.0001 par value per share

(Title of Class of Securities)

86889P208

(CUSIP Number)

James Evangelista, CFO
The Column Group III, LP, 1 Letterman Drive, Building D, Suite M-9
San Francisco, CA, 94129
(415) 865-2050

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

03/31/2026

(Date of Event Which Requires Filing of This Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

schemaVersion:

SCHEDULE 13D

CUSIP Number(s): 86889P208

1

Name of reporting person

The Column Group III GP, LP

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 2,962,544.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 2,962,544.00

11

Aggregate amount beneficially owned by each reporting person

2,962,544.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

23.6 %

14

Type of Reporting Person (See Instructions)

PN

Comment for Type of Reporting Person:

Consists of (i) 900,292 shares of Common Stock held of record by TCG III LP (as defined in Item 2(a) below), (ii) 485,830 shares of Common Stock which TCG III LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in its Current Report on Form 8-K filed with the Commission on March 28, 2025 (the Form 8-K), (iii) warrants to purchase 5,218 shares of Common Stock held by TCG III LP which are exercisable within 60 days of this Statement, (iv) 1,016,658 shares of Common Stock held of record by TCG III-A LP (as defined in Item 2(a) below), (v) 548,653 shares of Common Stock which TCG III-A LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K and (vi) warrants to purchase 5,893 shares of Common Stock held by TCG III-A LP which are exercisable within 60 days of this Statement. TCG III GP LP is the general partner of each of TCG III LP and TCG III-A LP and may be deemed to have voting, investment and dispositive power with respect to these securities. Peter Svennilson and Tim Kutzkey, a member of the Issuer's board of directors, are the managing partners of TCG III GP LP and may each be deemed to share voting, investment and dispositive power with respect to these securities. Excludes (a) warrants to purchase 594,625 shares of Common Stock held by TCG III LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations and (b) warrants to purchase 671,518 shares of Common Stock held by TCG III-A LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations. Based on 12,532,301 shares outstanding, comprised of (i) 11,486,707 shares of Common Stock outstanding as of March 19, 2026, as reported by the Issuer (as defined in Item 1(b) below) in its annual report on Form 10-K filed with the Securities and Exchange Commission (the Commission) on March 23, 2026 (the Form 10-K), plus (ii) 485,830 shares of Common Stock which TCG III LP has the right to acquire within 60 days of this Statement, plus (iii) 5,218 shares underlying warrants to purchase shares of Common Stock held by TCG III LP which are exercisable within 60 days of this Statement, plus (iv) 548,653 shares of Common Stock which TCG III-A LP has the right to acquire within 60 days of this Statement, plus (v) 5,893 shares underlying warrants to purchase shares of Common Stock held by TCG III-A LP which are exercisable within 60 days of this Statement.

SCHEDULE 13D

CUSIP Number(s): 86889P208

1

Name of reporting person

The Column Group III, LP

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

WC

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 1,391,340.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 1,391,340.00

11

Aggregate amount beneficially owned by each reporting person

1,391,340.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

11.6 %

14

Type of Reporting Person (See Instructions)

PN

Comment for Type of Reporting Person:

Consists of (i) 900,292 shares of Common Stock held of record by TCG III LP, (ii) 485,830 shares of Common Stock which TCG III LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K and (iii) warrants to purchase 5,218 shares of Common Stock held by TCG III LP which are exercisable within 60 days of this Statement. TCG III GP LP is the general partner of TCG III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. Peter Svennilson and Tim Kutzkey, a member of the Issuer's board of directors, are the managing partners of TCG III GP LP and may each be deemed to share voting, investment and dispositive power with respect to these securities. Excludes warrants to purchase 594,625 shares of Common Stock held by TCG III LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations. Based on 11,977,755 shares outstanding, comprised of (i) 11,486,707 shares of Common Stock outstanding as of March 19, 2026, as reported by the Issuer in the Form 10-K, plus (ii) 485,830 shares of Common Stock which TCG III LP has the right to acquire within 60 days of this Statement, plus (iii) 5,218 shares underlying warrants to purchase shares of Common Stock held by TCG III LP which are exercisable within 60 days of this Statement.

SCHEDULE 13D

CUSIP Number(s): 86889P208

1

Name of reporting person

The Column Group III-A, LP

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

WC

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 1,571,204.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 1,571,204.00

11

Aggregate amount beneficially owned by each reporting person

1,571,204.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

13.0 %

14

Type of Reporting Person (See Instructions)

PN

Comment for Type of Reporting Person:

Consists of (i) 1,016,658 shares of Common Stock held of record by TCG III-A LP, (ii) 548,653 shares of Common Stock which TCG III-A LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K and (iii) warrants to purchase 5,893 shares of Common Stock held by TCG III-A LP which are exercisable within 60 days of this Statement. TCG III GP LP is the general partner of TCG III-A LP and may be deemed to have voting, investment and dispositive power with respect to these securities. Peter Svennilson and Tim Kutzkey, a member of the Issuer's board of directors, are the managing partners of TCG III GP LP and may each be deemed to share voting, investment and dispositive power with respect to these securities. Excludes warrants to purchase 671,518 shares of Common Stock held by TCG III-A LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations. Based on 12,041,253 shares outstanding, comprised of (i) 11,486,707 shares of Common Stock outstanding as of March 19, 2026, as reported by the Issuer in the Form 10-K, plus (ii) 548,653 shares of Common Stock which TCG III-A LP has the right to acquire within 60 days of this Statement, plus (iii) 5,893 shares underlying warrants to purchase shares of Common Stock held by TCG III-A LP which are exercisable within 60 days of this Statement.

SCHEDULE 13D

CUSIP Number(s): 86889P208

1

Name of reporting person

The Column Group Opportunity III, LP

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

WC

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 862,068.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 862,068.00

11

Aggregate amount beneficially owned by each reporting person

862,068.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

7.2 %

14

Type of Reporting Person (See Instructions)

PN

Comment for Type of Reporting Person:

Consists of (i) 344,827 shares of Common Stock held of record by TCG Opportunity III LP (as defined in Item 2(a)) and (ii) 517,241 shares of Common Stock which TCG Opportunity III LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K. TCG Opportunity III GP LP (as defined in Item 2(a)) is the general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. TCG Opportunity III GP LLC (as defined in Item 2(a)) is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. Peter Svennilson and Tim Kutzkey, a member of the Issuer's board of directors, are the managing members of TCG Opportunity III GP LLC and may each be deemed to share voting, investment and dispositive power with respect to these securities. Excludes warrants to purchase 431,034 shares of Common Stock held by TCG Opportunity III LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations. Based on 12,003,948 shares outstanding, comprised of (i) 11,486,707 shares of Common Stock outstanding as of March 19, 2026, as reported by the Issuer in the Form 10-K, plus (ii) 517,241 shares of Common Stock which TCG Opportunity III LP has the right to acquire within 60 days of this Statement.

SCHEDULE 13D

CUSIP Number(s): 86889P208

1

Name of reporting person

The Column Group Opportunity III GP, LP

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 862,068.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 862,068.00

11

Aggregate amount beneficially owned by each reporting person

862,068.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

7.2 %

14

Type of Reporting Person (See Instructions)

PN

Comment for Type of Reporting Person:

Consists of (i) 344,827 shares of Common Stock held of record by TCG Opportunity III LP and (ii) 517,241 shares of Common Stock which TCG Opportunity III LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K. TCG Opportunity III GP LP is the general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. TCG Opportunity III GP LLC is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. Peter Svennilson and Tim Kutzkey, a member of the Issuer's board of directors, are the managing members of TCG Opportunity III GP LLC and may each be deemed to share voting, investment and dispositive power with respect to these securities. Excludes warrants to purchase 431,034 shares of Common Stock held by TCG Opportunity III LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations. Based on 12,003,948 shares outstanding, comprised of (i) 11,486,707 shares of Common Stock outstanding as of March 19, 2026, as reported by the Issuer in the Form 10-K, plus (ii) 517,241 shares of Common Stock which TCG Opportunity III LP has the right to acquire within 60 days of this Statement.

SCHEDULE 13D

CUSIP Number(s): 86889P208

1

Name of reporting person

TCG Opportunity III GP, LLC

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 862,068.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 862,068.00

11

Aggregate amount beneficially owned by each reporting person

862,068.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

7.2 %

14

Type of Reporting Person (See Instructions)

OO

Comment for Type of Reporting Person:

Consists of (i) 344,827 shares of Common Stock held of record by TCG Opportunity III LP and (ii) 517,241 shares of Common Stock which TCG Opportunity III LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K. TCG Opportunity III GP LP is the general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. TCG Opportunity III GP LLC is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. Peter Svennilson and Tim Kutzkey, a member of the Issuer's board of directors, are the managing members of TCG Opportunity III GP LLC and may each be deemed to share voting, investment and dispositive power with respect to these securities. Excludes warrants to purchase 431,034 shares of Common Stock held by TCG Opportunity III LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations. Based on 12,003,948 shares outstanding, comprised of (i) 11,486,707 shares of Common Stock outstanding as of March 19, 2026, as reported by the Issuer in the Form 10-K, plus (ii) 517,241 shares of Common Stock which TCG Opportunity III LP has the right to acquire within 60 days of this Statement.

SCHEDULE 13D

CUSIP Number(s): 86889P208

1

Name of reporting person

Tim Kutzkey

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 3,824,612.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 3,824,612.00

11

Aggregate amount beneficially owned by each reporting person

3,824,612.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

29.3 %

14

Type of Reporting Person (See Instructions)

IN

Comment for Type of Reporting Person:

Consists of (i) 900,292 shares of Common Stock held of record by TCG III LP, (ii) 485,830 shares of Common Stock which TCG III LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K, (iii) warrants to purchase 5,218 shares of Common Stock held by TCG III LP which are exercisable within 60 days of this Statement, (iv) 1,016,658 shares of Common Stock held of record by TCG III-A LP, (v) 548,653 shares of Common Stock which TCG III-A LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K, (vi) warrants to purchase 5,893 shares of Common Stock held by TCG III-A LP which are exercisable within 60 days of this Statement, (vii) 344,827 shares of Common Stock held of record by TCG Opportunity III LP and (viii) 517,241 shares of Common Stock which TCG Opportunity III LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K. TCG III GP LP is the general partner of each of TCG III LP and TCG III-A LP and may be deemed to have voting, investment and dispositive power with respect to these securities. TCG Opportunity III GP LP is the general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to the securities held by TCG Opportunity III LP. TCG Opportunity III GP LLC is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to the securities held by TCG Opportunity III LP. Peter Svennilson and Tim Kutzkey, a member of the Issuer's board of directors, are the managing partners of TCG III GP LP and the managing members of TCG Opportunity III GP LLC and may each be deemed to share voting, investment and dispositive power with respect to these securities. Excludes (a) warrants to purchase 594,625 shares of Common Stock held by TCG III, LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations, (b) warrants to purchase 671,518 shares of Common Stock held by TCG III-A LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations and (c) 431,034 shares of Common Stock held by TCG Opportunity III LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations. Based on 13,049,542 shares outstanding, comprised of (i) 11,486,707 shares of Common Stock outstanding as of March 19, 2026, as reported by the Issuer in the Form 10-K, plus (ii) 485,830 shares of Common Stock which TCG III LP has the right to acquire within 60 days of this Statement, plus (iii) 5,218 shares underlying warrants to purchase shares of Common Stock held by TCG III LP which are exercisable within 60 days of this Statement, plus (iv) 548,653 shares of Common Stock which TCG III-A LP has the right to acquire within 60 days of this Statement, plus (v) 5,893 shares underlying warrants to purchase shares of Common Stock held by TCG III-A LP which are exercisable within 60 days of this Statement, plus (vi) 517,241 shares of Common Stock which TCG Opportunity III LP has the right to acquire within 60 days of this Statement.

SCHEDULE 13D

CUSIP Number(s): 86889P208

1

Name of reporting person

Peter Svennilson

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

SWEDEN

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 3,824,612.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 3,824,612.00

11

Aggregate amount beneficially owned by each reporting person

3,824,612.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

29.3 %

14

Type of Reporting Person (See Instructions)

IN

Comment for Type of Reporting Person:

Consists of (i) 900,292 shares of Common Stock held of record by TCG III LP, (ii) 485,830 shares of Common Stock which TCG III LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K, (iii) warrants to purchase 5,218 shares of Common Stock held by TCG III LP which are exercisable within 60 days of this Statement, (iv) 1,016,658 shares of Common Stock held of record by TCG III-A LP, (v) 548,653 shares of Common Stock which TCG III-A LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K, (vi) warrants to purchase 5,893 shares of Common Stock held by TCG III-A LP which are exercisable within 60 days of this Statement, (vii) 344,827 shares of Common Stock held of record by TCG Opportunity III LP and (viii) 517,241 shares of Common Stock which TCG Opportunity III LP has the right to acquire within 60 days of this Statement in the second tranche of the Issuer's private placement transaction as disclosed by the Issuer in the Form 8-K. TCG III GP LP is the general partner of each of TCG III LP and TCG III-A LP and may be deemed to have voting, investment and dispositive power with respect to these securities. TCG Opportunity III GP LP is the general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to the securities held by TCG Opportunity III LP. TCG Opportunity III GP LLC is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to the securities held by TCG Opportunity III LP. Peter Svennilson and Tim Kutzkey, a member of the Issuer's board of directors, are the managing partners of TCG III GP LP and the managing members of TCG Opportunity III GP LLC and may each be deemed to share voting, investment and dispositive power with respect to these securities. Excludes (a) warrants to purchase 594,625 shares of Common Stock held by TCG III, LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations, (b) warrants to purchase 671,518 shares of Common Stock held by TCG III-A LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations and (c) 431,034 shares of Common Stock held by TCG Opportunity III LP which are not exercisable within 60 days of this Statement due to beneficial ownership limitations. Based on 13,049,542 shares outstanding, comprised of (i) 11,486,707 shares of Common Stock outstanding as of March 19, 2026, as reported by the Issuer in the Form 10-K, plus (ii) 485,830 shares of Common Stock which TCG III LP has the right to acquire within 60 days of this Statement, plus (iii) 5,218 shares underlying warrants to purchase shares of Common Stock held by TCG III LP which are exercisable within 60 days of this Statement, plus (iv) 548,653 shares of Common Stock which TCG III-A LP has the right to acquire within 60 days of this Statement, plus (v) 5,893 shares underlying warrants to purchase shares of Common Stock held by TCG III-A LP which are exercisable within 60 days of this Statement, plus (vi) 517,241 shares of Common Stock which TCG Opportunity III LP has the right to acquire within 60 days of this Statement.

SCHEDULE 13D

Item 1.	Security and Issuer
(a)	Title of Class of Securities: Common Stock, $0.0001 par value per share
(b)	Name of Issuer: Surrozen, Inc.
(c)	Address of Issuer's Principal Executive Offices: 171 Oyster Point Blvd, Suite 400, South San Francisco, CALIFORNIA , 94080.
Item 1 Comment: Explanatory Note: This Amendment No. 6 (this Amendment No. 6) supplements and amends the Schedule 13D relating to the Common Stock of the Issuer that was filed with the Commission on August 23, 2021, as amended by Amendment No. 1 that was filed with the Commission on February 13, 2023, by Amendment No. 2 that was filed with the Commission on April 8, 2024, by Amendment No. 3 that was filed with the Commission on April 17, 2024, Amendment No. 4 that was filed with the Commission on March 28, 2025 and by Amendment No. 5 that was filed with the Commission on January 22, 2026 (collectively, the Original Schedule 13D). This Amendment No. 6 is being filed to update the aggregate percentage of the Common Stock owned by the Reporting Persons due to dilution caused by the Issuer's sales of additional shares of Common Stock from time to time since the date of the Original 13D. Only those items that are reported are hereby amended; all other items reported in the Original Schedule 13D remain unchanged. Capitalized terms contained herein but not otherwise defined shall have the meanings ascribed to such terms in the Original Schedule 13D.
Item 2.	Identity and Background
(a)	This Statement is being filed by The Column Group III, LP (TCG III LP), The Column Group III-A, LP (TCG III-A LP), The Column Group III GP, LP (TCG III GP LP), The Column Group Opportunity III, LP (TCG Opportunity III LP), The Column Group Opportunity III GP, LP (TCG Opportunity III GP LP), TCG Opportunity III GP, LLC (TCG Opportunity III GP LLC, together with TCG III LP, TCG III-A LP, TCG III GP LP, TCG Opportunity III LP, and TCG Opportunity III GP LP, the Reporting Entities), Tim Kutzkey, a member of the Issuer's board of directors and Peter Svennilson. The Reporting Entities, Mr. Svennilson and Dr. Kutzkey are collectively referred to as the Reporting Persons. The agreement among the Reporting Persons to file jointly in accordance with the provisions of Rule 13d-1(k)(1) under the Act is attached as Exhibit 1 to Amendment No. 5. Each Reporting Person disclaims beneficial ownership of all securities reported in this Statement except to the extent of such Reporting Person's pecuniary interest therein, other than those securities reported herein as being held directly by such Reporting Person.
(b)	The address of the principal offices of each Reporting Entity 1 Letterman Drive, Building D, Suite M-900, San Francisco, CA 94129.
(c)	Each of TCG III LP, TCG III-A LP and TCG Opportunity III LP is a venture capital investment entity. TCG III GP LP is the general partner of each of TCG III LP and TCG III-A LP. TCG Opportunity III GP LP is the general partner of TCG Opportunity III LP. TCG Opportunity III GP LLC is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP. Dr. Kutzkey and Peter Svennilson are the managing partners of TCG III GP LP and the managing members of TCG Opportunity III GP LLC, and are each engaged through venture capital investment entities in acquiring, holding and disposing of interests in various companies for investment purposes.
(d)	During the past five years, none of the Reporting Persons have been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors).
(e)	None of the Reporting Persons are, nor during the last five years have been, a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws.
(f)	Each of TCG III GP LP, TCG III LP, TCG III-A LP, TCG Opportunity III LP and TCG Opportunity III GP LP is a limited partnership organized under the laws of the State of Delaware. TCG Opportunity III GP LLC is a limited company organized under the laws of the State of Delaware. Dr. Kutzkey is a citizen of the United States of America. Mr. Svennilson is a citizen of Sweden.
Item 3.	Source and Amount of Funds or Other Consideration
	The information set forth in Item 3 of the Original Schedule 13D is incorporated herein by reference.
Item 4.	Purpose of Transaction
	The information set forth in Item 4 of the Original Schedule 13D is incorporated herein by reference.
Item 5.	Interest in Securities of the Issuer
(a)	See Items 7-11 of the cover pages of this Amendment No. 6.
(b)	See Items 7-11 of the cover pages of this Amendment No. 6.
(c)	Except as reported in this Statement, none of the Reporting Persons has effected any transactions in the Issuer's securities within the past 60 days.
(d)	Under certain circumstances set forth in the limited partnership agreements of TCG III LP, TCG III-A LP and TCG Opportunity III LP, the general partner and limited partners of each of TCG III LP, TCG III-A LP and TCG Opportunity III LP may be deemed to have the right to receive dividends from, or the proceeds from, the sale of shares of the Issuer owned by such entity of which they are a partner.
(e)	Not applicable.
Item 6.	Contracts, Arrangements, Understandings or Relationships With Respect to Securities of the Issuer
	The information set forth in Item 6 of the Original Schedule 13D is incorporated herein by reference.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

The Column Group III GP, LP

Signature:	/s/ James Evangelista
Name/Title:	James Evangelista, Attorney-in-Fact
Date:	05/15/2026

The Column Group III, LP

Signature:	/s/ James Evangelista
Name/Title:	James Evangelista, Attorney-in-Fact
Date:	05/15/2026

The Column Group III-A, LP

Signature:	/s/ James Evangelista
Name/Title:	James Evangelista, Attorney-in-Fact
Date:	05/15/2026

The Column Group Opportunity III, LP

Signature:	/s/ James Evangelista
Name/Title:	James Evangelista, Attorney-in-Fact
Date:	05/15/2026

The Column Group Opportunity III GP, LP

Signature:	/s/ James Evangelista
Name/Title:	James Evangelista, Attorney-in-Fact
Date:	05/15/2026

TCG Opportunity III GP, LLC

Signature:	/s/ James Evangelista
Name/Title:	James Evangelista, Attorney-in-Fact
Date:	05/15/2026

Tim Kutzkey

Signature:	/s/ James Evangelista
Name/Title:	James Evangelista, Attorney-in-Fact
Date:	05/15/2026

Peter Svennilson

Signature:	/s/ James Evangelista
Name/Title:	James Evangelista, Attorney-in-Fact
Date:	05/15/2026

FAQ

What ownership stake does The Column Group report in Surrozen (SRZN)?

The Column Group III GP LP reports beneficial ownership of 2,962,544 Surrozen shares, representing 23.6% of the common stock. This figure includes shares and warrants exercisable within 60 days and rights to acquire shares from a private placement tranche.

How much of Surrozen’s stock do Tim Kutzkey and Peter Svennilson report owning?

Tim Kutzkey and Peter Svennilson each report beneficial ownership of 3,824,612 Surrozen shares, or 29.3% of the class. Their reported stakes aggregate holdings and near-term exercisable rights across several Column Group funds.

How are Surrozen’s outstanding shares calculated in this Schedule 13D/A?

The filing cites 11,486,707 Surrozen shares outstanding as of March 19, 2026, from the company’s Form 10-K. It then adds specific shares and warrant shares the Column Group entities can acquire within 60 days to derive ownership percentage denominators.

What role do warrants play in The Column Group’s Surrozen stake?

The Column Group funds hold warrants to acquire Surrozen shares, some exercisable within 60 days and included in beneficial ownership. Additional warrants, such as those for 594,625 and 671,518 shares in certain funds, are excluded because beneficial ownership limits prevent exercise within 60 days.

What is the connection between the private placement and these Surrozen ownership figures?

The filing includes shares that Column Group funds have the right to acquire in the second tranche of Surrozen’s private placement disclosed in a Form 8-K. These near-term acquisition rights are counted in beneficial ownership and affect the reported percentages.

Are The Column Group entities classified as investment firms in this Surrozen filing?

Yes. The filing states that TCG III LP, TCG III-A LP and TCG Opportunity III LP are venture capital investment entities. They acquire, hold and dispose of interests in various companies, including Surrozen, for investment purposes.