STOK insider Form 4 shows director sale, 323,774 shares remain

Rhea-AI Filing Summary

Stoke Therapeutics, Inc. (STOK) director reported an open-market sale of company stock. On 11/24/2025, the reporting person sold 40,472 shares of common stock at a weighted average price of $29.7173 per share, through multiple transactions within a price range of $29.50 to $30.12. After this sale, the director beneficially owned 323,774 shares of Stoke Therapeutics common stock in direct ownership form. The filing notes that the sale was made under a Rule 10b5-1 trading plan that was adopted on August 15, 2025.

Insider Trade Summary

Net Seller: 40,472 shares ($1,202,719)

Net Sell 1 txn

Insider Krainer Adrian R.

Role Director

Sold 40,472 shs ($1.20M)

Type	Security	Shares	Price	Value
Sale	Common Stock	40,472	$29.7173	$1.20M

Holdings After Transaction: Common Stock — 323,774 shares (Direct)

Footnotes (1)

1. The transaction reported on this Form 4 was executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 15, 2025. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $29.50 to $30.12 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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Form 4 Insider Transactions: What Each Field Means →

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Krainer Adrian R.

(Last) (First) (Middle)

C/O STOKE THERAPEUTICS, INC.

45 WIGGINS AVENUE

(Street)

BEDFORD MA 01730

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Stoke Therapeutics, Inc. [ STOK ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
11/24/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	11/24/2025		S(1)		40,472	D	$29.7173(2)	323,774	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The transaction reported on this Form 4 was executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 15, 2025.

2. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $29.50 to $30.12 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

	/s/ Jonathan Allan, Attorney-in-Fact	11/26/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transaction did Stoke Therapeutics (STOK) report on this Form 4?

The Form 4 reports that a director of Stoke Therapeutics sold 40,472 shares of common stock on 11/24/2025 in an open-market transaction.

At what price were the 40,472 STOK shares sold by the director?

The 40,472 shares of Stoke Therapeutics common stock were sold at a weighted average price of $29.7173 per share, with individual trades executed between $29.50 and $30.12 per share.

How many Stoke Therapeutics (STOK) shares does the insider own after the reported sale?

Following the reported sale, the director beneficially owned 323,774 shares of Stoke Therapeutics common stock in direct ownership.

Was the Stoke Therapeutics insider sale made under a Rule 10b5-1 trading plan?

Yes. The filing states that the transaction was executed pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 15, 2025.

What does the weighted average price disclosure mean for the STOK insider sale?

The filing explains that the reported price is a weighted average, and that the shares were sold in multiple trades between $29.50 and $30.12. The insider undertakes to provide full trade-by-trade detail upon request.

What is the reporting person’s relationship to Stoke Therapeutics (STOK)?

The reporting person is identified as a director of Stoke Therapeutics, Inc., with the Form 4 box for director checked.