Form 3: OrbiMed Entities Report Director Status; No STTK Securities

Rhea-AI Filing Summary

OrbiMed entities and OrbiMed Advisors LLC reported their relationship to Shattuck Labs (STTK) as directors but stated they do not beneficially own any securities of the issuer. The Form 3 lists three reporting entities at the same New York address and indicates the filing covers more than one reporting person. No non‑derivative or derivative holdings are reported.

Insights

Securities Analyst

TL;DR: Reporting parties are directors of STTK and report zero beneficial ownership, a routine initial Form 3 disclosure.

This initial Form 3 notifies the market that OrbiMed Advisors LLC, OrbiMed Capital GP IX LLC and OrbiMed Genesis GP LLC are related to Shattuck Labs as directors but currently hold no reported non‑derivative or derivative securities. The disclosure is administrative and does not reflect transactions, ownership stakes, or material changes to capital structure. Investor impact is minimal absent subsequent purchases or grants.

Corporate Governance Expert

TL;DR: Governance disclosure confirms director relationships without revealing ownership; no material governance or control concerns shown.

The filing documents director status for multiple affiliated reporting entities sharing the same address and signatory, and explicitly states "No securities are beneficially owned." From a governance perspective, this is a standard declaration. It raises no immediate governance flags such as undisclosed related‑party holdings or conflicting ownership claims. Materiality remains low until holdings or transactions are reported.

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SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person^*

ORBIMED ADVISORS LLC

(Last) (First) (Middle)

601 LEXINGTON AVENUE

54TH FLOOR

(Street)

NEW YORK NY 10022

(City) (State) (Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
08/25/2025

3. Issuer Name and Ticker or Trading Symbol
Shattuck Labs, Inc. [ STTK ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person^*

ORBIMED ADVISORS LLC

(Last) (First) (Middle)

601 LEXINGTON AVENUE

54TH FLOOR

(Street)

NEW YORK NY 10022

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

OrbiMed Capital GP IX LLC

(Last) (First) (Middle)

601 LEXINGTON AVENUE

54TH FLOOR

(Street)

NEW YORK NY 10022

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

OrbiMed Genesis GP LLC

(Last) (First) (Middle)

601 LEXINGTON AVENUE, 54TH FLOOR

(Street)

NEW YORK NY 10022

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

Explanation of Responses:

No securities are beneficially owned.

	/s/ Carl L. Gordon, Member of OrbiMed Advisors LLC	09/02/2025
	/s/ Carl L. Gordon, Member of OrbiMed Capital GP IX LLC	09/02/2025
	/s/ Carl L. Gordon, Member of OrbiMed Genesis GP LLC	09/02/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did the Form 3 filed for Shattuck Labs (STTK) disclose?

The Form 3 discloses that OrbiMed Advisors LLC, OrbiMed Capital GP IX LLC, and OrbiMed Genesis GP LLC are related to the issuer as directors and that no securities are beneficially owned by these reporting persons.

Which entities filed the initial statement for STTK?

The filing names OrbiMed Advisors LLC, OrbiMed Capital GP IX LLC, and OrbiMed Genesis GP LLC at the same New York address as the reporting parties.

Does the Form 3 report any stock options or derivative holdings for STTK?

No. The Form 3 shows no non‑derivative or derivative securities beneficially owned by the reporting persons.

Is this Form 3 reporting a change in ownership or a transaction for STTK?

No. The Form 3 is an initial statement indicating director relationships and explicitly states that there are no securities owned; it does not report purchases, sales, or ownership changes.