Redmile funds detail 9.9% Shattuck Labs (STTK) stake and warrant activity

Q: How many Shattuck Labs shares are tied to Redmile’s Pre-Funded Warrants?

Redmile funds hold Pre-Funded Warrants for up to 10,943,951 shares of Shattuck Labs common stock, including 5,647,258 shares attributable to RBI II, with 2,780,965 shares currently counted toward beneficial ownership due to the 9.99% Beneficial Ownership Limitation .

Q: What warrant exercises did Redmile report in June 2026 for STTK?

On June 3, 2026 , certain Redmile funds cashlessly exercised Pre-Funded Warrants and received 1,012,203 shares at an exercise price of $0.0001 per share . On June 9, 2026 , they exercised Common Warrants, paying about $4,444,022 in aggregate exercise price.

Filing Impact

(Moderate)

Filing Sentiment

(Neutral)

Form Type

SCHEDULE 13D/A

Rhea-AI Filing Summary

Redmile Group, LLC and affiliated entities filed Amendment No. 5 to their Schedule 13D on Shattuck Labs, Inc. (STTK), updating their ownership and recent warrant activity. The reporting persons may be deemed to beneficially own 9,819,084 shares of common stock, representing 9.9% of the class.

This includes 7,038,119 shares of common stock held by Redmile funds and, subject to a 9.99% Beneficial Ownership Limitation, 10,943,951 shares issuable upon exercise of Pre-Funded Warrants, of which 2,780,965 shares are counted for beneficial ownership purposes. Redmile funds exercised Common and Pre-Funded Warrants in June 2026, paying about $4.44 million in aggregate exercise price and separately buying additional Pre-Funded Warrants in an underwritten offering for about $3.99 million.

Key Figures

Beneficial ownership shares: 9,819,084 shares Percent of class owned: 9.9% Shares from cashless exercise: 1,012,203 shares +5 more

8 metrics

Beneficial ownership shares 9,819,084 shares Shares of Shattuck Labs common stock beneficially owned by reporting persons

Percent of class owned 9.9% Portion of Shattuck Labs common stock represented by 9,819,084 shares

Shares from cashless exercise 1,012,203 shares Common shares issued June 3, 2026 from cashless Pre-Funded Warrant exercise at $0.0001 per share

Common Warrant exercise cost $4,444,022 Approximate aggregate exercise price paid June 9, 2026 by participating Redmile funds

Shares underlying new Pre-Funded Warrants 1,000,000 shares Shares purchasable via Pre-Funded Warrants bought in underwritten offering at $3.9999 per warrant

Total shares issuable from Pre-Funded Warrants 10,943,951 shares Common shares issuable upon exercise of all Pre-Funded Warrants held by Redmile funds

Shares outstanding baseline 95,508,165 shares Common shares outstanding immediately after the underwritten offering including underwriters’ option

RBI II shared power shares 6,119,962 shares Shares of common stock with shared voting and dispositive power reported by RBI II

Key Terms

Pre-Funded Warrants, Beneficial Ownership Limitation, underwritten offering, shared voting power, +2 more

6 terms

Pre-Funded Warrants financial

"exercised on a cashless basis certain pre-funded warrants to purchase Common Stock (the "Pre-Funded Warrants")"

Pre-funded warrants are financial instruments that give investors the right to purchase a company's stock at a set price, but with most or all of the purchase price paid upfront. They function like a coupon or gift card for stock, allowing investors to buy shares later at a fixed price, which can be beneficial if they want to avoid future price increases. This makes them important for investors seeking flexibility and certainty in their investment plans.

Beneficial Ownership Limitation financial

"subject to the 9.99% beneficial ownership limitation (the "Beneficial Ownership Limitation")"

A beneficial ownership limitation is a rule that caps the percentage of a company’s shares an investor can be treated as owning or controlling for voting, regulatory or tax purposes. It matters to investors because it can restrict how many shares a person or group can buy or vote, affect takeover chances, and influence share liquidity and value — like a speed limit that prevents any single driver from taking over the whole road.

underwritten offering financial

"participated in an underwritten offering of the Issuer's Common Stock and Pre-Funded Warrants"

An underwritten offering is when a bank or group of banks agrees to buy all of a company's new shares or bonds and then resell them to outside investors, guaranteeing the company will raise a specific amount of money. It matters to investors because it adds certainty that the funding will close while increasing the number of shares or debt in the market, which can lower the price per share and change each existing owner's ownership percentage—think of a wholesaler buying an entire shipment from a maker before it reaches stores.

shared voting power financial

"Shared Voting Power 9,819,084.00"

Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.

shared dispositive power financial

"Shared Dispositive Power 9,819,084.00"

Schedule 13D regulatory

"This Amendment No. 5 to (this "Amendment") amends and supplements the filed with the SEC"

A Schedule 13D is a legal document that investors file with regulators when they buy a large enough stake in a company to potentially influence its management or decisions. It provides details about the investor’s intention, ownership stake, and plans, helping other investors understand who is gaining control and what their motives might be.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 06/11/2026 - 09:00 PM Accepted by SEC EDGAR 06/11/2026 - 09:00 PM

FAQ

What ownership stake does Redmile report in Shattuck Labs (STTK)?

Redmile and related reporting persons may be deemed to beneficially own 9,819,084 shares of Shattuck Labs common stock, representing 9.9% of the class, based on 95,508,165 shares outstanding after the underwritten offering plus certain warrant shares.

How many Shattuck Labs shares are tied to Redmile’s Pre-Funded Warrants?

Redmile funds hold Pre-Funded Warrants for up to 10,943,951 shares of Shattuck Labs common stock, including 5,647,258 shares attributable to RBI II, with 2,780,965 shares currently counted toward beneficial ownership due to the 9.99% Beneficial Ownership Limitation.

What warrant exercises did Redmile report in June 2026 for STTK?

On June 3, 2026, certain Redmile funds cashlessly exercised Pre-Funded Warrants and received 1,012,203 shares at an exercise price of $0.0001 per share. On June 9, 2026, they exercised Common Warrants, paying about $4,444,022 in aggregate exercise price.

What did Redmile elect to receive upon exercising Common Warrants in June 2026?

Upon June 9, 2026 Common Warrant exercises, participating Redmile funds elected to receive 340,106 shares of common stock and Pre-Funded Warrants for 3,757,624 shares. RBI II’s portion was Pre-Funded Warrants for 2,048,423 shares, for which it paid about $2,221,514.

How did Redmile participate in Shattuck Labs’ underwritten offering?

On June 9, 2026, certain Redmile funds (excluding RBI II) bought Pre-Funded Warrants in an underwritten offering, using about $3,999,900 of working capital to acquire warrants to purchase 1,000,000 shares of common stock at $3.9999 per warrant, each exercisable at $0.0001 per share.

What voting and dispositive powers does Redmile report over STTK shares?

Redmile and Jeremy C. Green each report 0 shares with sole voting or dispositive power and 9,819,084 shares with shared voting and shared dispositive power. RBI II reports 6,119,962 shares with shared voting and shared dispositive power and no sole powers.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934

(Amendment No. 5)

Shattuck Labs, Inc.

(Name of Issuer)

Common Stock, par value $0.0001 per share

(Title of Class of Securities)

82024L103

(CUSIP Number)

Redmile Group, LLC
Attn: Josh Garcia, 900 Larkspur Landing Circle, Suite 270
Larkspur, CA, 94939
(415) 489-9980

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

06/09/2026

(Date of Event Which Requires Filing of This Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

SCHEDULE 13D

Item 1.

Security and Issuer

(a)

Title of Class of Securities:

Common Stock, par value $0.0001 per share

(b)

Name of Issuer:

Shattuck Labs, Inc.

(c)

Address of Issuer's Principal Executive Offices:

500 W. 5th Street, Suite 1200, Austin, TEXAS , 78701.

Item 2.

Identity and Background

(a)

This Amendment No. 5 to Schedule 13D (this "Amendment") amends and supplements the Schedule 13D filed with the SEC on October 15, 2020, amendment No. 1 to the Schedule 13D filed with the SEC on December 21, 2023, amendment No. 2 to the Schedule 13D filed with the SEC on December 6, 2024, amendment No. 3 to the Schedule 13D filed with the SEC on August 6, 2025, and amendment No. 4 to the Schedule 13D filed with the SEC on August 26, 2025 (collectively, the "Prior Schedule 13D") by Redmile Group, LLC ("Redmile"), Jeremy C. Green, and Redmile Biopharma Investments II, L.P. ("RBI II") relating to the Common Stock of the Issuer. Capitalized terms used but not defined in this Amendment shall have the meanings set forth in the Prior Schedule 13D. Except as specifically amended by this Amendment, the Prior Schedule 13D is unchanged.

(b)

Item 2(b) of the Prior Schedule 13D is hereby amended and restated in its entirety as follows: Redmile: 900 Larkspur Landing Circle, Suite 270 Larkspur, California 94939 Jeremy C. Green: c/o Redmile Group, LLC (NY Office) 45 W. 27th Street, Floor 11 New York, NY 10001 RBI II: c/o Redmile Group, LLC 900 Larkspur Landing Circle, Suite 270 Larkspur, California 94939

Item 3.

Source and Amount of Funds or Other Consideration

Item 3 of the Prior Schedule 13D is hereby amended and supplemented in its entirety by adding the following paragraphs after the last paragraph of Item 3: On June 3, 2026, certain private investment funds managed by Redmile (the "Redmile Funds"), not including RBI II, exercised on a cashless basis certain pre-funded warrants to purchase Common Stock (the "Pre-Funded Warrants") in accordance with the terms thereof, at an exercise price of $0.0001 per share. The participating Redmile Funds were issued an aggregate of 1,012,203 shares of Common Stock by the Issuer, net of the warrant shares representing the aggregate exercise price. On June 9, 2026, certain Redmile Funds, including RBI II, exercised all of the Common Warrants held by such Redmile Funds in accordance with the terms thereof, which were exercisable, at the holder's sole discretion, for either Common Stock, at an exercise price of $1.0846 per share, or Pre-Funded Warrants, at an exercise price of $1.0845 per Pre-Funded Warrant. The participating Redmile Funds, including RBI II, elected to receive 340,106 shares of Common Stock and Pre-Funded Warrants to purchase an aggregate of 3,757,624 shares of Common Stock and utilized their working capital to pay the aggregate exercise price of approximately $4,444,022. Of the securities acquired by the participating Redmile Funds upon exercise of the Common Warrants, RBI II utilized its working capital to pay an aggregate exercise price of approximately $2,221,514 to receive Pre-Funded Warrants to purchase 2,048,423 shares of Common Stock. On June 9, 2026, certain Redmile Funds, not including RBI II, also participated in an underwritten offering of the Issuer's Common Stock and Pre-Funded Warrants (the "Underwritten Offering") and utilized their working capital in an aggregate amount of approximately $3,999,900 to acquire Pre-Funded Warrants to purchase 1,000,000 shares of Common Stock at a price of $3.9999 per Pre-Funded Warrant, each with an exercise price of $0.0001 per share.

Item 5.

Interest in Securities of the Issuer

(a)

Item 5(a) of the Prior Schedule 13D is hereby amended and restated in its entirety as follows: The aggregate amount of shares of Common Stock that may be deemed beneficially owned by the Reporting Persons is comprised of (i) 7,038,119 shares of Common Stock held by the Redmile Funds, including the 3,338,997 shares of Common Stock directly held by RBI II, and (ii) subject to the 9.99% beneficial ownership limitation (the "Beneficial Ownership Limitation"), 10,943,951 shares of Common Stock issuable upon exercise of the Pre-Funded Warrants, including the 5,647,258 shares of Common Stock issuable upon exercise of the Pre-Funded Warrants directly held by RBI II. The 2,780,965 shares of Common Stock issuable upon exercise of the Pre-Funded Warrants reported as beneficially owned by the Reporting Persons represent the maximum number of shares of Common Stock that could be issued upon exercise of those Pre-Funded Warrants subject to the Beneficial Ownership Limitation. All of the reported securities are directly owned by certain Redmile Funds. Redmile may be deemed to beneficially own these securities in its capacity as the investment manager of the Redmile Funds with discretion to vote and dispose of their portfolio securities. Mr. Green also may be deemed to beneficially own these securities as the principal of Redmile. Redmile and Mr. Green each disclaim beneficial ownership of the reported securities, except to the extent of its or his pecuniary interest in such securities, if any. Redmile and Mr. Green may be deemed to beneficially own 146,086 shares of Common Stock subject to options to purchase shares of Common Stock that are exercisable within 60 days of the date of this filing, and such amount is included in the number disclosed in (i) above. The stock options were granted to Mike Lee, a managing director of Redmile, in connection with his former service as a member of the Board of Directors, which ceased on August 25, 2025. Pursuant to the policies of Redmile, Mr. Lee holds the stock options as a nominee on behalf, and for the sole benefit, of Redmile and has assigned all economic, pecuniary and voting rights in respect of the stock options to Redmile. Percentage for each Reporting Person based on sum of: (i) 95,508,165 shares of Common Stock outstanding immediately after the Underwritten Offering (including the exercise of the underwriters' option to purchase additional shares of Common Stock), as reported by the Issuer in its Prospectus Supplement to the Prospectus dated January 21, 2026, which was filed with the Securities and Exchange Commission on June 11, 2026, plus (ii) 2,780,965 shares of Common Stock issuable upon exercise of certain Pre-Funded Warrants directly held by the Redmile Funds (including RBI II), which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of those Warrants.

(b)

Item 5(b) of the Prior Schedule 13D is hereby amended and restated in its entirety as follows: Redmile: (1) Sole Voting Power: 0 (2) Shared Voting Power: 9,819,084 (3) Sole Dispositive Power: 0 (4) Shared Dispositive Power: 9,819,084 Jeremy C. Green: (1) Sole Voting Power: 0 (2) Shared Voting Power: 9,819,084 (3) Sole Dispositive Power: 0 (4) Shared Dispositive Power: 9,819,084 RBI II: (1) Sole Voting Power: 0 (2) Shared Voting Power: 6,119,962 (3) Sole Dispositive Power: 0 (4) Shared Dispositive Power: 6,119,962

(c)

See the response to Item 3. Except as disclosed in Item 3, no reportable transactions were effected by any Reporting Persons during the past sixty days.

Item 6.

Contracts, Arrangements, Understandings or Relationships With Respect to Securities of the Issuer

Item 6 of the Prior Schedule 13D is hereby amended and supplemented in its entirety by adding the following paragraphs prior to the last paragraph of Item 6: Pre-Funded Warrants to Purchase Common Stock Pre-Funded Warrants were acquired by the Redmile Funds, not including RBI II, in the Underwritten Offering at a price of $3.9999 per Pre-Funded Warrant and entitle the holder to purchase up to an aggregate of 1,000,000 shares of Common Stock, subject to the Beneficial Ownership Blocker, at an exercise price of $0.0001 per Pre-Funded Warrant. The Pre-Funded Warrants are exercisable by the holder at any time on or after the issuance date until fully exercised. The foregoing summary of the Pre-Funded Warrants is not intended to be complete and is qualified in its entirety by reference to the full text of the Form of Pre-Funded Warrant, which is filed as Exhibit 99.12 to this Schedule 13D and is incorporated herein by reference.

Item 7.

Material to be Filed as Exhibits.

Exhibit 99.12 Form of Pre-Funded Warrant (incorporated by reference to Exhibit 4.1 to the Issuer's Current Report on Form 8-K filed on June 11, 2026).

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Redmile Group, LLC

Signature:	/s/ Jeremy C. Green
Name/Title:	Managing Member
Date:	06/11/2026

Jeremy C. Green

Signature:	/s/ Jeremy C. Green
Name/Title:	Jeremy C. Green
Date:	06/11/2026

Redmile Biopharma Investments II, L.P.

Signature:	/s/ Jeremy C. Green
Name/Title:	Managing Member of Redmile Biopharma Investments II (GP), LLC, general partner of Redmile Biopharma Investments II, L.P.
Date:	06/11/2026

Source: View Original Filing on SEC EDGAR