Takeda officer sells 34,535 ADS at $18.54

Takeda’s Chief Transformation Officer sold 34,535 ADS on September 14, 2026, and now directly holds 191,522 ADS.

Rhea-AI Filing Summary

TAKEDA PHARMACEUTICAL CO LTD (TAK) reported that Chief Transformation Officer Lauren Rusckowski Duprey sold 34,535 American Depositary Shares on September 14, 2026 in an open-market or private transaction at $18.54 per share. After this sale, she directly holds 191,522 American Depositary Shares, and no Rule 10b5-1 plan is reported.

Insider Trade Summary

Net Seller: 34,535 shares

Net Sell 1 txn

Insider Duprey Lauren Rusckowski

Role Chief Transformation Officer

Sold 34,535 shs ($640K)

Type	Security	Shares	Price	Value
Sale	American Depositary Shares	34,535	$18.54	$640K

Holdings After Transaction: American Depositary Shares — 191,522 shares (Direct)

Key Figures

Shares sold: 34,535 American Depositary Shares Sale price per share: $18.54 per American Depositary Share Shares held after transaction: 191,522 American Depositary Shares +1 more

4 metrics

Shares sold 34,535 American Depositary Shares Sale reported for September 14, 2026

Sale price per share $18.54 per American Depositary Share Price reported for the September 14, 2026 sale

Shares held after transaction 191,522 American Depositary Shares Direct ownership after the September 14, 2026 sale

Net shares sold 34,535 American Depositary Shares Net change from this Form 4, all from one sale

Key Terms

American Depositary Shares, open-market or private transaction, Rule 10b5-1

3 terms

American Depositary Shares financial

"reported that Lauren Rusckowski Duprey sold 34,535 American Depositary Shares"

American depositary shares (ADSs) are a way for investors in the United States to buy shares of foreign companies without dealing with international markets directly. They represent ownership in a foreign company's stock and are traded on U.S. stock exchanges, making it easier for American investors to buy, sell, and own parts of companies from around the world.

open-market or private transaction financial

"sale in an open-market or private transaction at $18.54 per share"

Rule 10b5-1 regulatory

"no Rule 10b5-1 plan is reported for this transaction"

Rule 10b5-1 is a regulation that allows company insiders to buy or sell their shares at predetermined times, even if they have access to non-public information. It acts like setting a schedule in advance for transactions, helping prevent accusations of unfair trading. This rule provides a way for insiders to plan trades transparently, giving investors confidence that these transactions are not based on hidden information.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What insider transaction did TAK (Takeda Pharmaceutical Co Ltd) disclose?

Takeda disclosed that Chief Transformation Officer Lauren Rusckowski Duprey sold 34,535 American Depositary Shares on September 14, 2026 in a sale reported as an open-market or private transaction.

At what price were the TAK American Depositary Shares sold in this Form 4?

The reported sale price was $18.54 per American Depositary Share. This price is stated on the Form 4 as a per-share figure for the 34,535 American Depositary Shares sold.

How many TAK shares does the insider hold after the reported sale?

Following the transaction, Lauren Rusckowski Duprey directly holds 191,522 American Depositary Shares of Takeda Pharmaceutical Co Ltd, as reported in the post-transaction holdings field.

Was the TAK insider sale made under a Rule 10b5-1 trading plan?

No. The filing’s Rule 10b5-1 checkbox is not selected, which indicates that the reported sale was not affirmed as being made under a Rule 10b5-1 trading plan.

Who is the insider involved in the TAK Form 4 transaction and what is their role?

The reporting person is Lauren Rusckowski Duprey, who is identified in the filing as Takeda Pharmaceutical Co Ltd’s Chief Transformation Officer and an officer of the company.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 09/15/2026 - 09:13 PM Accepted by SEC EDGAR 09/15/2026 - 09:12 PM Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Duprey Lauren Rusckowski

(Last) (First) (Middle)

45-55 HAYDEN AVE.

(Street)

LEXINGTON MASSACHUSETTS 02139

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
TAKEDA PHARMACEUTICAL CO LTD [ TAK ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Transformation Officer

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
09/14/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
American Depositary Shares	09/14/2026		S		34,535	D	$18.54	191,522	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

Remarks:

	/s/ Kate Huleatt, by power of attorney, for Lauren Duprey	09/15/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)