[Form 3] TALPHERA, INC. Initial Statement of Beneficial Ownership

Rhea-AI Filing Summary

Talphera, Inc. (TLPH) filed a Form 3 for director Joseph Todisco. The filing states that no securities are beneficially owned by the reporting person as of the event date 10/14/2025. The form indicates it was filed by one reporting person and reflects Todisco’s role as a director.

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0104
Estimated average burden
hours per response:			0.5

1. Name and Address of Reporting Person^*

Todisco Joseph

(Last) (First) (Middle)

C/O TALPHERA, INC.

1850 GATEWAY, SUITE 175

(Street)

SAN MATEO CA 94404

(City) (State) (Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
10/14/2025

3. Issuer Name and Ticker or Trading Symbol
TALPHERA, INC. [ TLPH ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

No securities are beneficially owned.

	/s/ Joseph Todisco	10/16/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Talphera (TLPH) report in this Form 3?

The Form 3 reports that director Joseph Todisco beneficially owns no securities.

What is the event date on the Talphera (TLPH) Form 3?

The event date is 10/14/2025.

Who is the reporting person in Talphera’s (TLPH) Form 3?

The reporting person is Joseph Todisco, identified as a Director.

Does the Form 3 indicate any ownership by the reporting person?

No. The filing states, “No securities are beneficially owned.”

Is this Talphera (TLPH) Form 3 filed by one or multiple reporting persons?

It is filed by one reporting person.

Is the reporting person a 10% owner of Talphera (TLPH)?

No. The Director box is checked; the 10% Owner box is not.