[Form 4] Thermo Fisher Scientific, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Insider transactions by Marc N. Casper, Chairman & CEO of Thermo Fisher Scientific (TMO). The Form 4 reports two open-market disposals on 08/28/2025, selling 686.571 shares and 724.767 shares at $489.74 per share. After those sales the filing shows beneficial ownership reported as approximately 114,487.052 and 113,762.285 shares (direct holdings). The filing also discloses indirect holdings of 11,300 shares through the Alison Casper 2020 Irrevocable Trust, 14,608 shares via Floral Park Associates, Inc., and 5,000 shares via the MNC 2020 Irrevocable Trust. The Form 4 is signed by an attorney-in-fact on behalf of Mr. Casper on 09/02/2025.

Insights

Securities Analyst

TL;DR: Routine insider share disposals by CEO; transaction sizes are modest relative to overall holdings.

The filing documents two small open-market sales of common stock on 08/28/2025 at $489.74 per share. The reported quantities (686.571 and 724.767 shares) represent routine dispositions rather than large block trades. Reported direct and indirect beneficial ownership lines remain significant, and there is no indication of unusual trading patterns or derivative activity. For investors this appears to be a routine liquidity event by the reporting person, not a corporate governance or operational disclosure.

Corporate Governance Expert

TL;DR: Properly reported Form 4 showing direct disposals and separate indirect holdings; signature executed by attorney-in-fact.

The Form 4 lists Mr. Casper as both Director and Chairman & CEO and discloses direct sales alongside explicit statements disclaiming beneficial ownership of certain indirectly held shares except for pecuniary interest. Indirect holdings are itemized by trust and entity. The form is executed by an attorney-in-fact, consistent with delegated filing procedures. The disclosure meets Section 16 reporting conventions and does not contain derivative transactions or amendments requiring further explanation.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

CASPER MARC N

(Last) (First) (Middle)

168 THIRD AVENUE

(Street)

WALTHAM MA 02451

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
THERMO FISHER SCIENTIFIC INC. [ TMO ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chairman & CEO

3. Date of Earliest Transaction (Month/Day/Year)
08/28/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	08/28/2025		F		686.571	D	$489.74	114,487.052	D
Common Stock	08/28/2025		F		724.767	D	$489.74	113,762.285	D
Common Stock								11,300	I	By Alison Casper 2020 Irrevocable Trust(1)
Common Stock								14,608	I	By Floral Park Associates, Inc.
Common Stock								5,000	I	By MNC 2020 Irrevocable Trust(2)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The reporting person disclaims beneficial ownership of the securities reported herein as indirectly beneficially owned, except to the extent of any pecuniary interest therein.

2. The reporting person disclaims beneficial ownership of the securities reported herein as indirectly beneficially owned, except to the extent of any pecuniary interest therein.

	/s/ Melodie T. Morin, Attorney-in-Fact for Marc N. Casper	09/02/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Marc N. Casper (TMO) report on the Form 4?

The Form 4 reports two open-market dispositions on 08/28/2025: 686.571 and 724.767 shares sold at $489.74 per share.

How many shares does Marc Casper indirectly own according to the filing?

The filing lists indirect holdings of 11,300 shares (Alison Casper 2020 Irrevocable Trust), 14,608 shares (Floral Park Associates, Inc.), and 5,000 shares (MNC 2020 Irrevocable Trust).

Were any derivative securities reported in this Form 4 for TMO?

No. Table II for derivative securities shows no reported acquisitions, dispositions, or holdings; only non-derivative common stock transactions are reported.

When were the transactions executed and when was the Form 4 signed?

The transactions occurred on 08/28/2025 and the Form 4 was signed by an attorney-in-fact on 09/02/2025.

What positions does the reporting person hold at Thermo Fisher Scientific?

Marc N. Casper is reported as a Director and as Chairman & CEO of Thermo Fisher Scientific (TMO).