Tango Therapeutics officer plans $340K share sale

An officer associated with Tango Therapeutics has filed a Rule 144 notice to sell up to 15,231 shares of TNGX common stock acquired through equity compensation.

Rhea-AI Filing Summary

Tango Therapeutics, Inc. (TNGX) has an affiliate officer, Jessica Newcomb, filing a notice to sell common stock under Rule 144. The filing covers up to 15,231 shares of Tango Therapeutics common stock to be sold through Morgan Stanley Smith Barney LLC, with an aggregate market value of $340,108.23 as of September 22, 2026.

The shares include 10,236 shares acquired upon vesting of Employee Stock Purchase Plan shares during the period from April 30, 2024 through April 30, 2025, and 4,995 shares acquired upon vesting of restricted stock units during the period from February 5, 2024 through February 3, 2025. Tango Therapeutics reports 168,610,367 shares of common stock outstanding, providing context for the size of this planned sale.

Key Figures

Shares to be sold under Rule 144: 15,231 shares Aggregate market value of planned sale: $340,108.23 Shares from Employee Stock Purchase Plan vesting: 10,236 shares +3 more

6 metrics

Shares to be sold under Rule 144 15,231 shares Common stock of Tango Therapeutics covered by the Form 144 notice

Aggregate market value of planned sale $340,108.23 Value of 15,231 Tango Therapeutics shares as of September 22, 2026

Shares from Employee Stock Purchase Plan vesting 10,236 shares Acquired upon ESPP vesting from April 30, 2024 through April 30, 2025

Shares from restricted stock unit vesting 4,995 shares Acquired upon RSU vesting from February 5, 2024 through February 3, 2025

Shares outstanding 168,610,367 shares Tango Therapeutics common stock outstanding, as referenced in the notice

Issuer phone number 857-320-4900 Contact phone number for Tango Therapeutics

Key Terms

Rule 144, Restricted Stock Units, Employee Stock Purchase Plan, aggregate market value, +1 more

5 terms

Rule 144 regulatory

"See the definition of "person" in paragraph (a) of Rule 144."

Rule 144 is a U.S. securities regulation that sets conditions under which restricted or insider-held shares can be legally resold to the public, such as required holding periods, availability of public information, limits on how much can be sold at once, and certain filing requirements. For investors it matters because it determines when previously locked-up shares can enter the market — like a release valve that can increase supply, affect share price, and signal insider intent.

Restricted Stock Units financial

"Restricted Stock Units | Issuer | | | 4995 | 02/05/2024"

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

Employee Stock Purchase Plan financial

"Employee Stock Purchase Plan | Issuer | | | 10236 | 04/30/2024"

An employee stock purchase plan is a company program that lets workers buy shares through small payroll deductions, often at a discount to the market price and after a set offering period. Think of it like a workplace savings plan that turns into ownership: it encourages employees to share in the company’s success and can create predictable buying or selling of stock that investors watch because it affects supply, demand and employee incentives.

aggregate market value financial

"15231 | 340108.23 | 168610367 | 09/22/2026"

Aggregate market value is the combined price you would pay to buy all outstanding shares of a company or all companies in a group at current market prices — essentially the sum of each stock’s market capitalization. It matters to investors because it shows the overall size and weight of an investment or sector (like the total cost to buy every piece of a puzzle), helps compare scale across companies or markets, and influences index composition and risk exposure.

securities to be sold financial

"The 10,236 securities to be sold were acquired upon the vesting"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does the Form 144 filing disclose for Tango Therapeutics (TNGX)?

The filing discloses that officer Jessica Newcomb plans to sell up to 15,231 shares of Tango Therapeutics common stock under Rule 144, with an aggregate market value of $340,108.23, through Morgan Stanley Smith Barney LLC as of September 22, 2026.

How many Tango Therapeutics (TNGX) shares is the insider planning to sell?

The notice covers up to 15,231 shares of Tango Therapeutics common stock. These consist of 10,236 shares from Employee Stock Purchase Plan vesting and 4,995 shares from restricted stock unit vesting over the stated periods.

What is the approximate market value of the TNGX shares in this Form 144?

The planned sale amount has an aggregate market value of $340,108.23 for the 15,231 shares of Tango Therapeutics common stock referenced in the notice, based on the pricing information used in the Form 144 as of September 22, 2026.

How were the Tango Therapeutics (TNGX) shares in this Form 144 acquired?

The filing states that 10,236 shares were acquired upon vesting of Employee Stock Purchase Plan shares from April 30, 2024 through April 30, 2025, and 4,995 shares were acquired upon vesting of restricted stock units from February 5, 2024 through February 3, 2025.

How large is this planned TNGX sale relative to Tango Therapeutics’ outstanding shares?

Tango Therapeutics reports 168,610,367 shares of common stock outstanding. The 15,231 shares covered by this Form 144 notice represent a small portion of that total, based solely on the figures disclosed.

Who is the broker handling the potential sale of TNGX shares in this Form 144?

The notice identifies Morgan Stanley Smith Barney LLC Executive Financial Services at 1 New York Plaza, New York, as the broker through which the 15,231 shares of Tango Therapeutics common stock may be sold on NASDAQ.

AI-generated analysis. How Rhea-AI works. Not financial advice.

See more from StockTitan in Google Search and AI answers. Adds StockTitan as a preferred source · opens Google

Add on Google Not now

Available on EDGAR 09/22/2026 - 04:15 PM Accepted by SEC EDGAR 09/22/2026 - 04:14 PM Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0002130408
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	TANGO THERAPEUTICS INC
SEC File Number	001-39485
Address of Issuer	201 BROOKLINE AVENUE, SUITE 901 BOSTON MASSACHUSETTS 02215
Phone	8573204900
Name of Person for Whose Account the Securities are To Be Sold	Jessica Newcomb
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza 8th Floor New York NY 10004	15231	340108.23	168610367	09/22/2026	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	02/05/2024	Restricted Stock Units	Issuer			4995	02/05/2024	N/A
Common	04/30/2024	Employee Stock Purchase Plan	Issuer			10236	04/30/2024	N/A

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Nothing to Report

144: Remarks and Signature

Remarks	The 10,236 securities to be sold were acquired upon the vesting of ESPP shares during the period of 4/30/2024 through 4/30/2025 The 4,995 securities to be sold were acquired upon the vesting of restricted stock units during the period of 2/5/2024 through 2/3/2025
Date of Notice	09/22/2026
Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1	06/23/2026
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ Jessica Newcomb
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)