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Twist Bioscience (TWST) CEO executes 19,952-share option exercise and sale under 10b5-1 plan

(Neutral)
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Twist Bioscience Corp Chief Executive Officer Emily M. Leproust reported an option exercise and share sale on August 12, 2026. She exercised 19,952 Employee Stock Options at an exercise price of $26.66 per share, receiving an equal number of common shares. The same day, she sold 19,952 common shares at a weighted average price of $125.0756 per share in transactions executed under a previously adopted Rule 10b5-1 trading plan.

The option exercised relates to a grant expiring on November 18, 2028. Additional stock option holdings are reported with exercise prices of $5.95, $8.82, $23.33, and $67.85, with expirations between 2025 and 2030, showing remaining equity-based incentives.

Positive

  • None.

Negative

  • None.
Insider Leproust Emily M.
Role Chief Executive Officer
Sold 19,952 shs ($2.50M)
Approx. gross sale proceeds $2.50M
Approx. exercise cost $532K
Approx. pre-tax spread $1.96M
Type Security Shares Price Value
Exercise Employee Stock Option (right to buy) F7 19,952 $0.00 $0.00
Exercise Common Stock F1 19,952 $26.66 $532K
Sale Common Stock F1, F2 19,952 $125.0756 $2.50M
holding Employee Stock Option (right to buy) F3 -- -- --
holding Employee Stock Option (right to buy) F4 -- -- --
holding Employee Stock Option (right to buy) F5 -- -- --
holding Employee Stock Option (right to buy) F6 -- -- --
Holdings After Transaction: Employee Stock Option (right to buy) — 133,269 shares (Direct); Common Stock — 818,938 shares (Direct)
Footnotes (7)
  1. F1. The transactions reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on May 27, 2025.
  2. F2. Represents the weighted average sales price per share. The shares sold at prices ranging from $125.00 to $125.25 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
  3. F3. The option is immediately exercisable. 25% of the shares subject to the option vested on September 1, 2016 and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
  4. F4. 25% of the shares subject to the option vested on October 24, 2020, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
  5. F5. Represents performance stock options granted to the reporting person on September 1, 2020, that vested and became exercisable on December 19, 2022 as a result of the reporting person having met the applicable performance criteria.
  6. F6. The option is immediately exercisable. 10% of the shares subject to the option vested on September 28, 2017, 15% of the shares subject to the option vested on September 28, 2018, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
  7. F7. 20% of the shares subject to the option vested and became exercisable on October 31, 2019 and 1/60th of the shares subject to the option vest and become exercisable on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
Options Exercised 19,952 shares Employee Stock Options exercised into common stock on August 12, 2026
Option Exercise Price $26.66 per share Exercise price for 19,952 Employee Stock Options
Shares Sold 19,952 shares Common shares sold on August 12, 2026
Weighted Average Sale Price $125.0756 per share Sale price, with trades between $125.00 and $125.25
10b5-1 Plan Adoption Date May 27, 2025 Date the Rule 10b5-1 trading plan governing these trades was adopted
Option Expiration November 18, 2028 Expiration date of the exercised Employee Stock Option grant
Rule 10b5-1 trading plan regulatory
"transactions were effected pursuant to a Rule 10b5-1 trading plan previously adopted"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
Employee Stock Option (right to buy) financial
"security_title: Employee Stock Option (right to buy)"
weighted average sales price financial
"Represents the weighted average sales price per share. The shares sold at prices"
performance stock options financial
"Represents performance stock options granted to the reporting person on September 1, 2020"

FAQ

What did TWST CEO Emily Leproust report on this Form 4?

Emily Leproust reported exercising 19,952 stock options at $26.66 per share and selling 19,952 common shares at a weighted average of $125.0756 per share on August 12, 2026, under a Rule 10b5-1 trading plan.

How many Twist Bioscience (TWST) shares did the CEO sell and at what price?

The CEO sold 19,952 common shares of Twist Bioscience at a weighted average price of $125.0756 per share. The footnote states sales occurred in a range from $125.00 to $125.25 per share.

What options did the TWST CEO exercise in this Form 4 transaction?

Emily Leproust exercised 19,952 Employee Stock Options with an exercise price of $26.66 per share, converting them into an equal number of common shares. The option has an expiration date of November 18, 2028 and vesting terms described in a footnote.

Were the TWST CEO’s trades made under a Rule 10b5-1 plan?

Yes. A footnote states the transactions were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2025. Such plans pre-schedule trades, which can reduce the informational value of transaction timing for investors.

What other stock options does the TWST CEO hold according to this filing?

Reported option holdings include Employee Stock Options with exercise prices of $5.95, $8.82, $23.33, and $67.85 per share, expiring between September 28, 2025 and August 31, 2030, each tied to Twist Bioscience common stock.

Does this TWST Form 4 show how many shares the CEO owns after the transactions?

The Form 4 reports the shares transacted but does not provide a populated figure for total shares owned following the transactions. Therefore, the exact post-transaction common stock holdings are not specified in the reported data here.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Leproust Emily M.

(Last)(First)(Middle)
C/O TWIST BIOSCIENCE CORPORATION
681 GATEWAY BLVD.

(Street)
SOUTH SAN FRANCISCO CALIFORNIA 94080

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Twist Bioscience Corp [ TWST ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Chief Executive Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
08/12/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock08/12/2026M(1)19,952A$26.66838,890D
Common Stock08/12/2026S(1)19,952D$125.0756(2)818,938D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Option (right to buy)$5.95 (3)09/28/2025Common Stock00D
Employee Stock Option (right to buy)$23.33 (4)10/23/2029Common Stock0131,290D
Employee Stock Option (right to buy)$67.8512/19/202208/31/2030Common Stock064,950(5)D
Employee Stock Option (right to buy)$8.82 (6)09/28/2027Common Stock075,439D
Employee Stock Option (right to buy)$26.6608/12/2026M19,952 (7)11/18/2028Common Stock19,952$0133,269D
Explanation of Responses:
1. The transactions reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on May 27, 2025.
2. Represents the weighted average sales price per share. The shares sold at prices ranging from $125.00 to $125.25 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
3. The option is immediately exercisable. 25% of the shares subject to the option vested on September 1, 2016 and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
4. 25% of the shares subject to the option vested on October 24, 2020, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
5. Represents performance stock options granted to the reporting person on September 1, 2020, that vested and became exercisable on December 19, 2022 as a result of the reporting person having met the applicable performance criteria.
6. The option is immediately exercisable. 10% of the shares subject to the option vested on September 28, 2017, 15% of the shares subject to the option vested on September 28, 2018, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
7. 20% of the shares subject to the option vested and became exercisable on October 31, 2019 and 1/60th of the shares subject to the option vest and become exercisable on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
Remarks:
/s/ Kendra Fox, as Attorney-in-Fact for Emily M. Leproust08/14/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)