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Twist Bioscience Corp (TWST) CEO sells shares in tax “sell to cover”

(High)
(Negative)
Form Type
4

Rhea-AI Filing Summary

Twist Bioscience Corp Chief Executive Officer Emily M. Leproust reported selling 5,101 shares of Common Stock on 2026-08-03 at an average price of $85.3212 per share. According to the disclosure, these shares were sold to cover tax withholding obligations upon vesting of Restricted Stock Units under the company’s equity incentive plans and "do not represent discretionary trades." Following this transaction, Leproust directly holds 818,938 shares of Common Stock and maintains various employee stock options with specified vesting schedules, including performance stock options exercisable at $67.85 per share on 64,950 underlying shares that vested after meeting performance criteria.

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Insider Leproust Emily M.
Role Chief Executive Officer
Sold 5,101 shs ($435K)
Type Security Shares Price Value
Sale Common Stock F1 5,101 $85.3212 $435K
holding Employee Stock Option (right to buy) F2 -- -- --
holding Employee Stock Option (right to buy) F3 -- -- --
holding Employee Stock Option (right to buy) F4 -- -- --
holding Employee Stock Option (right to buy) F5 -- -- --
holding Employee Stock Option (right to buy) F6 -- -- --
Holdings After Transaction: Common Stock — 818,938 shares (Direct); Employee Stock Option (right to buy) — 64,950 shares (Direct)
Footnotes (6)
  1. F1. Represents the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of a tax withholding obligation to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.
  2. F2. The option is immediately exercisable. 25% of the shares subject to the option vested on September 1, 2016 and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
  3. F3. The option is immediately exercisable. 10% of the shares subject to the option vested on September 28, 2017, 15% of the shares subject to the option vested on September 28, 2018, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
  4. F4. 20% of the shares subject to the option vested and became exercisable on October 31, 2019 and 1/60th of the shares subject to the option vest and become exercisable on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
  5. F5. 25% of the shares subject to the option vested on October 24, 2020, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
  6. F6. Represents performance stock options granted to the reporting person on September 1, 2020, that vested and became exercisable on December 19, 2022 as a result of the reporting person having met the applicable performance criteria.
Shares sold 5,101 shares Common Stock sold on 2026-08-03 to cover tax withholding obligations
Average sale price $85.3212 per share Price for 5,101-share Common Stock sale on 2026-08-03
Shares owned after sale 818,938 shares Direct Common Stock holdings following the 2026-08-03 transaction
Performance option exercise price $67.8500 Exercise price of performance stock options expiring 2030-08-31
Underlying shares for performance options 64,950 shares Performance stock options granted 2020-09-01, vested 2022-12-19 after meeting criteria
Restricted Stock Units financial
"in connection with the vesting of Restricted Stock Units."
Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.
"sell to cover" transaction financial
"obligation to be funded by a "sell to cover" transaction"
performance stock options financial
"Represents performance stock options granted to the reporting person"

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FAQ

What did Twist Bioscience (TWST) CEO Emily Leproust report in this Form 4?

Emily Leproust reported a sale of 5,101 Twist Bioscience (TWST) shares of Common Stock on 2026-08-03 at an average price of $85.3212 per share. The filing also details her remaining direct holdings and several outstanding employee stock option awards.

Why did the Twist Bioscience (TWST) CEO sell 5,101 shares in this filing?

The 5,101-share sale by the Twist Bioscience (TWST) CEO was to cover tax withholding obligations related to vesting Restricted Stock Units. The disclosure states these sales are mandated by the company’s equity incentive plans and “do not represent discretionary trades.”

How many Twist Bioscience (TWST) shares does the CEO hold after this Form 4 sale?

After the reported transaction, the Twist Bioscience (TWST) CEO directly holds 818,938 shares of Common Stock. This figure reflects her position following the 5,101-share sale executed on 2026-08-03 to satisfy tax withholding from Restricted Stock Unit vesting.

At what price were the Twist Bioscience (TWST) shares sold in this Form 4?

The Twist Bioscience (TWST) shares were sold at an average price of $85.3212 per share. The Form 4 describes this as a sale of 5,101 shares of Common Stock conducted on 2026-08-03, specifically to fund tax withholding obligations tied to Restricted Stock Unit vesting.

What stock options for Twist Bioscience (TWST) does the CEO report holding?

The CEO reports several employee stock options on Twist Bioscience (TWST) shares with various exercise prices and expirations, including performance stock options exercisable at $67.85 per share on 64,950 underlying shares, which vested after meeting specified performance criteria.

Is the Twist Bioscience (TWST) CEO’s reported sale under a trading plan?

The filing notes the sale was to cover tax withholding under the company’s equity incentive plans and explicitly states the transactions “do not represent discretionary trades.” The document’s Rule 10b5-1 checkbox is not marked as being under such a trading plan.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Leproust Emily M.

(Last)(First)(Middle)
C/O TWIST BIOSCIENCE CORPORATION
681 GATEWAY BLVD.

(Street)
SOUTH SAN FRANCISCO CALIFORNIA 94080

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Twist Bioscience Corp [ TWST ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Chief Executive Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
08/03/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock08/03/2026S5,101(1)D$85.3212818,938D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Option (right to buy)$5.95 (2)09/28/2025Common Stock00D
Employee Stock Option (right to buy)$8.82 (3)09/28/2027Common Stock075,439D
Employee Stock Option (right to buy)$26.66 (4)11/18/2028Common Stock0266,539D
Employee Stock Option (right to buy)$23.33 (5)10/23/2029Common Stock0131,290D
Employee Stock Option (right to buy)$67.8512/19/202208/31/2030Common Stock64,95064,950(6)D
Explanation of Responses:
1. Represents the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of a tax withholding obligation to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.
2. The option is immediately exercisable. 25% of the shares subject to the option vested on September 1, 2016 and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
3. The option is immediately exercisable. 10% of the shares subject to the option vested on September 28, 2017, 15% of the shares subject to the option vested on September 28, 2018, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
4. 20% of the shares subject to the option vested and became exercisable on October 31, 2019 and 1/60th of the shares subject to the option vest and become exercisable on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
5. 25% of the shares subject to the option vested on October 24, 2020, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
6. Represents performance stock options granted to the reporting person on September 1, 2020, that vested and became exercisable on December 19, 2022 as a result of the reporting person having met the applicable performance criteria.
Remarks:
/s/ Kendra Fox, as Attorney-in-Fact for Emily M. Leproust08/05/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)