[Form 4] Twist Bioscience Corp Insider Trading Activity

Rhea-AI Filing Summary

Paula Green, Senior Vice President of Human Resources at Twist Bioscience Corp (TWST), reported a non‑discretionary sale of 9,724 common shares on 10/06/2025 at an effective price of $32.187 per share to satisfy tax withholding tied to vested Performance Stock Units (PSUs).

After the sell‑to‑cover, the reporting person beneficially owns 114,678 shares. The filing was submitted under Form 4 and signed by an attorney‑in‑fact on 10/08/2025. The sale was mandated by the issuer's equity plan election and is described as not a discretionary trade.

Positive

• Sale was non‑discretionary and intended solely to satisfy tax withholding for vested PSUs
• Reporting continues with clear disclosure of shares sold, price, and remaining beneficial ownership

Negative

• Direct holdings decreased by 9,724 shares following the sell‑to‑cover transaction

Insights

Compensation Governance Expert

Sell‑to‑cover tax withholding reduced holdings; transaction was non‑discretionary.

The reported 9,724‑share sale on 10/06/2025 is described as a required "sell to cover" to satisfy tax withholding for vested PSUs rather than a voluntary disposition. Such transactions are common when equity awards vest and the plan elects to satisfy withholding by selling shares.

This action does not indicate active trading intent by the reporting person but does lower direct share ownership to 114,678 shares. Monitor future Forms 4 for discretionary sales or additional equity exercises within the next reporting period.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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OMB Number:			3235-0287
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Green Paula

(Last) (First) (Middle)

C/O TWIST BIOSCIENCE CORPORATION

681 GATEWAY BLVD.

(Street)

SOUTH SAN FRANCISCO CA 94080

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Twist Bioscience Corp [ TWST ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	SVP of Human Resources

3. Date of Earliest Transaction (Month/Day/Year)
10/06/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	10/06/2025		S		9,724(1)	D	$32.187	114,678	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Represents the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Performance Stock Units ("PSUs"). These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of a tax withholding obligation to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

Remarks:

	/s/ Kendra Fox, as Attorney-in-Fact for Paula Green	10/08/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Paula Green (TWST) report on Form 4?

The Form 4 reports a sale of 9,724 shares on 10/06/2025 at $32.187 per share to cover tax withholding from vested PSUs.

Why were the shares sold in this Form 4 filing?

The filing states the shares were sold under the issuer's equity plan as a sell‑to‑cover to satisfy tax withholding obligations tied to vested Performance Stock Units.

How many shares does the reporting person own after the transaction?

After the sale the reporting person beneficially owns 114,678 shares.

Was this a discretionary trade by the insider?

No. The filing describes the sale as mandated by the issuer's election and not a discretionary trade by the reporting person.

When was the Form 4 signed and filed?

The filing bears a signature by an attorney‑in‑fact dated 10/08/2025.