Artisan Reports 10.6% Stake in Twist Bioscience (6.41M Shares)

Rhea-AI Filing Summary

Artisan Partners group reported beneficial ownership of 6,410,900 shares of Twist Bioscience Corporation common stock, representing 10.6% of the outstanding class based on 07/30/2025 share count. The filing shows no sole voting or dispositive power; instead the filers report shared voting power of 5,303,412 shares and shared dispositive power of 6,410,900. The shares are held for discretionary clients of Artisan Partners Limited Partnership and, according to the certification, were acquired in the ordinary course of business and not with the purpose of changing control. The report is filed as a joint Schedule 13G amendment and includes a joint filing agreement signed on 10/07/2025.

Positive

• Disclosure of a sizeable passive stake of 6,410,900 shares (10.6%), improving transparency for investors
• Certification of ordinary-course acquisition reduces immediate regulatory concerns about control intent

Negative

• Concentrated ownership at 10.6% increases susceptibility to large rebalancing by the adviser
• No sole voting power reported, which may limit predictable engagement or support in contested matters

Insights

Institutional Ownership Analyst

Large passive stake disclosed; shared control, not an activist move.

The group reports 6,410,900 shares, equal to 10.6% of the class, held for discretionary clients under shared voting and dispositive arrangements. That size crosses common 5% disclosure and is material to shareholder base concentration.

Risks and dependencies include client redemptions or portfolio rebalancing that could change holdings; there is no stated intent to influence control and the certification affirms ordinary-course acquisition. Watch holdings in subsequent filings and any Schedule 13D that would indicate a strategic change within a typical regulatory window.

Corporate Governance Specialist

Shared voting power implies collective decision-making across Artisan entities.

The report shows 5,303,412 shares with shared voting power and full shared dispositive power over 6,410,900 shares, reflecting the intertwined structure of Artisan Partners entities disclosed in the filing. This structure centralizes stewardship while identifying multiple filing entities.

Monitor any proxy-related communications or changes in voting alignments ahead of annual meetings or material corporate actions; changes in the voting share count would be the clearest near-term signal of altered governance influence.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 3)

Twist Bioscience Corporation

(Name of Issuer)

Common Stock

(Title of Class of Securities)

90184D100

(CUSIP Number)

09/30/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. 90184D100

1

Names of Reporting Persons

Artisan Partners Asset Management Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 5,303,412.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 6,410,900.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

6,410,900.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

10.6 %

12

Type of Reporting Person (See Instructions)

HC

Comment for Type of Reporting Person: (g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.

SCHEDULE 13G

CUSIP No. 90184D100

1

Names of Reporting Persons

Artisan Partners Holdings LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 5,303,412.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 6,410,900.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

6,410,900.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

10.6 %

12

Type of Reporting Person (See Instructions)

HC

Comment for Type of Reporting Person: (g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.

SCHEDULE 13G

CUSIP No. 90184D100

1

Names of Reporting Persons

Artisan Investments GP LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 5,303,412.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 6,410,900.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

6,410,900.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

10.6 %

12

Type of Reporting Person (See Instructions)

HC

Comment for Type of Reporting Person: (g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.

SCHEDULE 13G

CUSIP No. 90184D100

1

Names of Reporting Persons

Artisan Partners Limited Partnership

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 5,303,412.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 6,410,900.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

6,410,900.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

10.6 %

12

Type of Reporting Person (See Instructions)

IA

Comment for Type of Reporting Person: (e) Artisan Partners Limited Partnership is an investment adviser registered under section 203 of the Investment Advisers Act of 1940. (g) Artisan Partners Holdings LP is the sole limited partner of Artisan Partners Limited Partnership and the sole member of Artisan Investments GP LLC; Artisan Investments GP LLC is the general partner of Artisan Partners Limited Partnership; Artisan Partners Asset Management Inc. is the general partner of Artisan Partners Holdings LP.

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Twist Bioscience Corporation
(b)	Address of issuer's principal executive offices: 681 Gateway Blvd, South San Francisco, CA 94080
Item 2.
(a)	Name of person filing: Artisan Partners Asset Management Inc. ("APAM") Artisan Partners Holdings LP ("Artisan Holdings") Artisan Investments GP LLC ("Artisan Investments") Artisan Partners Limited Partnership ("APLP")
(b)	Address or principal business office or, if none, residence: APAM, Artisan Holdings, Artisan Investments, and APLP are all located at: 875 East Wisconsin Avenue, Suite 800 Milwaukee, WI 53202
(c)	Citizenship: APAM is a Delaware corporation; Artisan Holdings is a Delaware limited partnership; Artisan Investments is a Delaware limited liability company; APLP is a Delaware limited partnership
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 90184D100
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 6,410,900
(b)	Percent of class: 10.6% (based on 60,360,925 shares outstanding as of 07/30/2025)
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: None
	(ii) Shared power to vote or to direct the vote: 5,303,412
	(iii) Sole power to dispose or to direct the disposition of: None
	(iv) Shared power to dispose or to direct the disposition of: 6,410,900
Item 5.	Ownership of 5 Percent or Less of a Class.
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. The shares reported herein have been acquired on behalf of discretionary clients of APLP. Persons other than APLP are entitled to receive all dividends from, and proceeds from the sale of, those shares. None of those persons, to the knowledge of APAM, Artisan Holdings, Artisan Investments, or APLP has an economic interest in more than 5% of the class.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Artisan Partners Asset Management Inc.

Signature:	/s/ Gregory K. Ramirez
Name/Title:	Gregory K. Ramirez, Executive Vice President of Artisan Partners Asset Management Inc.
Date:	10/07/2025

Artisan Partners Holdings LP

Signature:	/s/ Gregory K. Ramirez
Name/Title:	Gregory K. Ramirez, Executive Vice President of Artisan Partners Asset Management Inc., as the general partner of Artisan Partners Holdings LP
Date:	10/07/2025

Artisan Investments GP LLC

Signature:	/s/ Gregory K. Ramirez
Name/Title:	Gregory K. Ramirez, Vice President of Artisan Investments GP LLC
Date:	10/07/2025

Artisan Partners Limited Partnership

Signature:	/s/ Gregory K. Ramirez
Name/Title:	Gregory K. Ramirez, Vice President of Artisan Investments GP LLC, as the general partner of Artisan Partners Limited Partnership
Date:	10/07/2025

Comments accompanying signature: Exhibit Index Exhibit 1 - Joint Filing Agreement dated 10/7/2025 by and among Artisan Partners Asset Management Inc., Artisan Partners Holdings LP, Artisan Investments GP LLC, and Artisan Partners Limited Partnership.

FAQ

What stake in Twist Bioscience (TWST) did Artisan Partners disclose?

Artisan Partners reported beneficial ownership of 6,410,900 shares, representing 10.6% of TWST based on 60,360,925 shares outstanding as of 07/30/2025.

Does Artisan Partners claim control of Twist Bioscience in this filing?

No. The filing states the shares were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing control; no sole voting or dispositive power is reported.

How much voting power does the Artisan group report?

The filers report shared voting power of 5,303,412 shares and shared dispositive power of 6,410,900 shares; sole voting/dispositive power is 0.

On whose behalf are the shares held?

The shares were acquired on behalf of discretionary clients of Artisan Partners Limited Partnership; the filing notes no single client is known to hold an economic interest over 5%.

When was the joint filing agreement signed?

The exhibit lists a Joint Filing Agreement dated 10/07/2025 and the signatures are dated the same day.