Unicycive Therapeutics filings document the regulatory, financing, governance, and operating disclosures of a Nasdaq-listed clinical-stage biotechnology company focused on kidney disease therapies. Form 8-K reports furnish financial results and business updates, including disclosures related to oxylanthanum carbonate, NDA activity, manufacturing matters, and the company’s cash and capital resources.
The filing record also covers common stock registered on the Nasdaq Capital Market, emerging growth company status, at-the-market equity sales under a shelf registration statement, and board and executive-governance matters. Proxy materials document director elections, auditor ratification, stockholder voting mechanics, and annual meeting procedures, while other current reports address securities litigation risk tied to public statements about the OLC program.
Octagon Capital Advisors and related funds report a sub-5% passive stake in Unicycive Therapeutics, Inc. They disclose beneficial ownership of 1,000,000 shares of Unicycive common stock, representing 4.7% of the class as of a 21,491,396-share base reported on November 12, 2025.
The shares are held through Octagon Investments Master Fund LP and Octagon Biotech Opportunities Fund I LP, with Octagon Capital Advisors LP as investment manager and Dr. Ting Jia as control person. The filing states the position is held in the ordinary course of business and not for the purpose of changing or influencing control of Unicycive.
Integrated Core Strategies (US) LLC, together with Millennium Management LLC, Millennium Group Management LLC and Israel A. Englander, reports beneficial ownership of 1,172,667 shares of Unicycive Therapeutics, Inc. common stock, representing 5.5% of the outstanding class as of 01/16/2026. The filing shows no sole voting or dispositive power, with all voting and disposal rights reported as shared among the reporting persons.
The shares are held through entities subject to voting control and investment discretion by Millennium Management LLC and other affiliated investment managers, with Millennium Group Management LLC as managing member and Mr. Englander as sole voting trustee of its managing member. The reporting parties state that the securities were not acquired and are not held for the purpose of changing or influencing control of Unicycive and are instead reported on a passive basis under Schedule 13G.
Unicycive Therapeutics, Inc. has amended its existing at-the-market equity program with Guggenheim Securities to expand potential common stock sales. The company previously could sell shares of common stock with an aggregate offering price of up to $50,000,000 under its Form S-3 shelf registration. As of November 14, 2025, Amendment No. 1 to the Sales Agreement increases the maximum aggregate offering price that may be sold in the ATM offering to $100,000,000. The ATM offering allows the company to issue and sell shares from time to time under its effective shelf registration statement and related sales agreement prospectus, as supplemented.
Unicycive Therapeutics (UNCY) filed a Form 8-K stating it issued a press release announcing financial results for the three months ended September 30, 2025 and provided a business update. The press release is furnished as Exhibit 99.1. The company notes the information under Item 2.02, including Exhibit 99.1, is being furnished and not filed under Section 18 of the Exchange Act.
Unicycive Therapeutics filed its Q3 2025 10-Q, showing larger resources and continued R&D investment. Cash and cash equivalents were $42.7 million as of September 30, 2025, up from $26.1 million at year-end 2024, reflecting equity activity. Total assets were $50.6 million and stockholders’ equity was $37.5 million.
The company reported a Q3 2025 net loss of $6.0 million and a nine‑month net loss of $11.9 million. Operating expenses were $7.3 million in Q3 (R&D $3.0 million; G&A $4.4 million). Other income benefited from a $1.1 million non‑cash gain from the change in fair value of warrant liabilities in Q3, and $9.8 million for the nine months.
Operating cash outflows were $23.3 million for the nine months. To fund operations, Unicycive sold 8,046,736 shares via its sales agreement with Guggenheim at an average price of $4.94, paying $1.2 million in commissions and receiving approximately $38.6 million in net proceeds. A 1‑for‑10 reverse stock split became effective in June 2025. 20,850,363 shares were outstanding as of September 30, 2025, and 21,491,396 as of November 12, 2025.
Unicycive Therapeutics (UNCY) furnished an 8-K with preliminary cash data and a regulatory update. The company expects to report approximately $42 million in cash and cash equivalents as of September 30, 2025, based on preliminary, unaudited figures. The company’s independent registered public accounting firm has not reviewed these figures, and complete quarterly results will appear in the upcoming Form 10-Q for the quarter ended September 30, 2025.
Unicycive also furnished a press release announcing an update from its meeting with the U.S. Food and Drug Administration and the timing of the resubmission of its New Drug Application for Oxylanthanum Carbonate, following a Complete Response Letter dated June 30, 2025.
Unicycive Therapeutics director Gaurav Aggarwal reported a Form 4 disclosing a non-derivative purchase of 652,900 shares of common stock on 08/25/2025. Following the transaction, the report shows beneficial ownership of 1,789,915 shares attributed indirectly through Vivo Opportunity Fund Holdings L.P., of which the reporting person is a managing member. The filing also reports a disposition of 3,199.21 shares of Series A-2 Prime Preferred Stock (issued March 14, 2024) and explains each preferred share converts using an original per-share price of $1,000 divided by $4.90, subject to blocking provisions. The reporting person disclaims beneficial ownership except for pecuniary interest.
Unicycive Therapeutics, Inc. disclosed that, after June 30, 2025, it sold 3,549,846 shares of common stock under a sales agreement with Guggenheim Securities, LLC. The shares were sold at an average price of $4.56 per share, generating net proceeds of approximately $16.3 million for the company.
This at-the-market style equity financing increases Unicycive’s cash resources but also adds new shares to its common stock base. The filing does not detail specific uses for the funds, only that the proceeds were received by the company.
Great Point Partners, LLC and two associated individuals filed a Schedule 13G/A reporting joint beneficial ownership of 796,558 shares of Unicycive Therapeutics, Inc. common stock, representing 6.24% of the 12,768,239 shares outstanding cited from the issuer's June 20, 2025 filing. The filing shows shared voting and dispositive power over those shares and no sole voting or dispositive power. The record holders are Biomedical Value Fund, L.P. (510,494 shares) and Biomedical Offshore Value Fund, Ltd. (286,064 shares); Great Point is investment manager of both and disclaims beneficial ownership except to the extent of pecuniary interests. The Reporting Persons executed a Joint Filing Agreement dated August 14, 2025, and certified the holdings were not acquired to change or influence control.