Welcome to our dedicated page for Vertex Pharmaceuticals SEC filings (Ticker: VRTX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) SEC filings page on Stock Titan provides access to the company’s U.S. Securities and Exchange Commission disclosures, including current reports on Form 8-K and other key documents. Vertex is a global biotechnology company with approved medicines in cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia and acute pain, and a broad clinical pipeline in kidney disease, neuropathic pain, type 1 diabetes and myotonic dystrophy type 1. Its SEC filings give investors and analysts detailed insight into financial performance, risk factors and material events affecting the business.
Recent Form 8-K filings from Vertex have reported quarterly financial results and related guidance under Item 2.02, Results of Operations and Financial Condition. These filings typically reference accompanying press releases that summarize revenue trends, research and development spending and updates across the company’s portfolio, including CFTR modulators such as ALYFTREK and TRIKAFTA, CASGEVY gene-edited cell therapy and JOURNAVX for acute pain. Other 8-K items may address changes in key executives or other corporate developments when they occur.
On Stock Titan, Vertex filings are updated in near real time as they appear on the SEC’s EDGAR system. AI-powered summaries help explain the main points of lengthy documents, so users can quickly understand how new information may relate to VRTX stock without reading every page. For example, AI summaries can highlight key themes in earnings-related 8-Ks, note significant changes in guidance or spending, and point out disclosures related to the progress of pivotal trials or regulatory submissions.
In addition to 8-Ks, users can review Vertex’s annual and quarterly reports when available, as well as any proxy materials and registration statements that may be filed. AI analysis tools on Stock Titan can surface trends across multiple filings, making it easier to track how Vertex’s financial profile and pipeline narrative evolve over time. This page is a useful starting point for anyone researching VRTX from a regulatory and disclosure perspective, complementing price charts, news and other fundamental data.
Vertex Pharmaceuticals director Bruce I. Sachs reported an automatic grant of deferred stock units tied to his board service. On January 15, 2026, he acquired 107.088 deferred stock units at a reference price of $443.56 per unit, bringing his total to 15,564.521 deferred stock units held directly.
Each deferred stock unit represents one share of Vertex common stock and will be paid out in common stock at the earliest of Sachs leaving the board, a change of control of the company, or his disability or death. This filing reflects equity-based compensation rather than an open-market stock purchase or sale.
Vertex Pharmaceuticals executive Ourania Tatsis, EVP and Chief Regulatory & Quality Officer, reported selling 4,500 shares of Vertex common stock on 01/07/2026 at a price of $474.99 per share. After this transaction, she beneficially owned 42,293 shares, all held directly.
The filing notes that the sale was made pursuant to Dr. Tatsis’ company-approved trading plan under Rule 10b5-1, which was entered into on 08/21/2025. Such plans are pre-arranged programs that allow insiders to sell stock according to preset terms, helping them diversify holdings while addressing concerns about trading on material nonpublic information.
Vertex Pharmaceuticals executive Charles F. Jr. Wagner, EVP, CO & FO, reported an option exercise and share sale in company stock. On 01/06/2026 he exercised 9,532 stock options at an exercise price of $189.38 per share, receiving the same number of Vertex common shares. That same day, he sold 9,532 common shares at a price of $461 per share, a transaction coded as a sale. After these transactions, he directly owned 37,725 shares of Vertex common stock. The filing notes that the sale was made under Mr. Wagner’s company-approved Rule 10b5-1 trading plan, which was entered into on 05/09/2025, and that the exercised options were fully vested.
Vertex Pharmaceuticals insider Ourania Tatsis has filed a notice to sell common stock under Rule 144. The filing covers 4,500 shares of Vertex common stock to be sold through Fidelity Brokerage Services on NASDAQ, with an aggregate market value of $2,137,455.00, against 253,718,831 shares outstanding.
The shares to be sold were acquired mainly through restricted stock vesting on several dates in 2021 and 2024, plus a small purchase through the employee stock purchase plan in May 2024. The notice also reports that Tatsis sold 4,500 Vertex common shares on 12/03/2025 for gross proceeds of $2,024,955.40. By signing, the seller represents not knowing any undisclosed material adverse information about the company’s operations.
Vertex Pharmaceuticals' EVP, CO & FO reported pre-planned stock sales under a Rule 10b5-1 trading plan. On 12/03/2025, the officer sold 7,000 shares of Vertex common stock at $451 per share and another 7,000 shares at $461 per share, both reported as open-market sales. These transactions were made pursuant to a company-approved Rule 10b5-1 trading plan that Mr. Wagner entered into on 5/9/2025. After the reported sales, he beneficially owned 37,725 shares of Vertex common stock directly.
Vertex Pharmaceuticals executive Dr. Ourania Tatsis reported an open market sale of company stock. On 12/03/2025, she sold 4,500 shares of Vertex common stock at a weighted average price of $449.99 per share, with individual sale prices ranging from $449.99 to $450.00. The transaction was coded as an open market sale and was made under a company-approved Rule 10b5-1 trading plan that Dr. Tatsis entered into on 08/21/2025. After this sale, she beneficially owned 46,793 shares of Vertex common stock directly.
A director of Vertex Pharmaceuticals (VRTX) reported a change in ownership of the company’s common stock. On 11/19/2025, the director recorded a transaction in which 800 shares of Vertex common stock were disposed of, coded as transaction type “G”. The shares were reported at a price of $0, indicating no cash consideration was recorded for this movement of shares in the form.
After this transaction, the director beneficially owns 6,315 shares of Vertex common stock in direct ownership. The filing is made on Form 4, which is used to report changes in insider ownership for directors, officers, and significant shareholders.
Vertex Pharmaceuticals (VRTX) executive Mark Atkinson reported a planned stock sale. As Executive Vice President and Chief Technical Operations Officer, he filed a Form 4 showing the sale of 2,500 shares of Vertex common stock on 11/17/2025 at a price of $434.58 per share.
After this transaction, he beneficially owned 16,852 shares directly. The filing notes that the sale was made under a company-approved Rule 10b5-1 trading plan that Mr. Atkinson entered into on 08/11/2025, meaning the trades were pre-arranged under SEC rules designed to allow insiders to sell shares according to a preset plan.
Vertex Pharmaceuticals (VRTX) reported insider transactions by its Executive Chairman and Director, Dr. Jeffrey Leiden. On 11/13/2025 and 11/14/2025, he exercised stock options to acquire Vertex common stock at exercise prices of $91.05 and $86.52 per share, then sold portions of the shares in the open market.
Reported sales included 18,528 shares at a weighted average price of $440.22, 1,160 shares at $441.05, 32,234 shares at $440.30, and 21,330 shares at $441.35, plus smaller additional amounts. After these transactions, Dr. Leiden beneficially owned 24,026 Vertex shares directly and 440 shares through a 401(k), along with vested stock options. The filing notes the trades were made under a company-approved Rule 10b5-1 trading plan entered into on 8/6/2025.
Vertex Pharmaceuticals (VRTX) reported higher Q3 results. Total revenues were $3,076.4 million, up from $2,771.9 million a year ago, driven by TRIKAFTA/KAFTRIO at $2,653.6 million and ALYFTREK at $247.0 million. Net income rose to $1,082.9 million with diluted EPS of $4.20 versus $4.01. Operating income was $1,186.2 million.
Year-to-date, total revenues reached $8,811.3 million and net income was $2,762.1 million. U.S. product revenues were $1,976.3 million; Europe contributed $836.9 million. “Other revenues” of $30.7 million year-to-date included upfront payments related to povetacicept regional agreements. The balance sheet remained strong with cash and cash equivalents of $4,939.6 million and long-term marketable securities of $5,722.8 million. The company repurchased 4.5 million shares for $1.9 billion year-to-date and has $3.5 billion remaining under its 2025 authorization. CASGEVY and JOURNAVX contributed $16.9 million and $19.6 million, respectively, within other product revenues in Q3.