Welcome to our dedicated page for Vertex Pharmaceuticals SEC filings (Ticker: VRTX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) SEC filings page on Stock Titan provides access to the company’s U.S. Securities and Exchange Commission disclosures, including current reports on Form 8-K and other key documents. Vertex is a global biotechnology company with approved medicines in cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia and acute pain, and a broad clinical pipeline in kidney disease, neuropathic pain, type 1 diabetes and myotonic dystrophy type 1. Its SEC filings give investors and analysts detailed insight into financial performance, risk factors and material events affecting the business.
Recent Form 8-K filings from Vertex have reported quarterly financial results and related guidance under Item 2.02, Results of Operations and Financial Condition. These filings typically reference accompanying press releases that summarize revenue trends, research and development spending and updates across the company’s portfolio, including CFTR modulators such as ALYFTREK and TRIKAFTA, CASGEVY gene-edited cell therapy and JOURNAVX for acute pain. Other 8-K items may address changes in key executives or other corporate developments when they occur.
On Stock Titan, Vertex filings are updated in near real time as they appear on the SEC’s EDGAR system. AI-powered summaries help explain the main points of lengthy documents, so users can quickly understand how new information may relate to VRTX stock without reading every page. For example, AI summaries can highlight key themes in earnings-related 8-Ks, note significant changes in guidance or spending, and point out disclosures related to the progress of pivotal trials or regulatory submissions.
In addition to 8-Ks, users can review Vertex’s annual and quarterly reports when available, as well as any proxy materials and registration statements that may be filed. AI analysis tools on Stock Titan can surface trends across multiple filings, making it easier to track how Vertex’s financial profile and pipeline narrative evolve over time. This page is a useful starting point for anyone researching VRTX from a regulatory and disclosure perspective, complementing price charts, news and other fundamental data.
Vertex Pharmaceuticals CEO & President Reshma Kewalramani reported open-market sales of 40,000 shares of Vertex common stock on February 27, 2026 under a pre-arranged Rule 10b5-1 trading plan entered into on November 17, 2025. The shares were sold at prices ranging from $479.75 to $496.95, and she held 98,278 shares directly after the final transaction.
Vertex Pharmaceuticals EVP and CMO Carmen Bozic sold common stock in a planned transaction. On February 27, 2026, she completed an open-market sale of 2,329 shares of Vertex common stock at an average price of $480.31 per share. After the sale, she directly owned 37,734 shares. The trade was made under a pre-established Rule 10b5-1 trading plan entered on November 20, 2025.
Joy Liu reported proposed sales of company common stock under Form 144. The notice lists multiple sales and recent transactions: 552 shares on 12/29/2025, 1,385 shares on 01/05/2026, 812 shares on 02/12/2026, and 9,320 shares on 02/13/2026. The filing also shows a grant/vesting of 892 restricted shares on 02/10/2025.
Vertex Pharmaceuticals senior vice president and chief accounting officer Kristen Ambrose reported an open-market sale of 357 shares of common stock at $483.36 per share. After this transaction, she directly holds 6,624 shares. The sale was made under a pre-established, company-approved Rule 10b5-1 trading plan.
VRTX submitted a Form 144 notice reporting the proposed sale of 40,000 common shares. The filing lists an aggregate dollar amount of $19,738,905.28 and shows 254,034,190 shares on the line that includes 02/27/2026.
The entries list multiple restricted stock vesting dates (02/10/2025, 02/17/2025, 02/24/2025, 02/26/2025) with vesting quantities of 9,681, 6,998, 8,282, and 15,039 shares respectively. The form identifies Fidelity Brokerage Services LLC as the broker on a NASDAQ-listed common security.
Vertex Pharmaceuticals executive Charles F. Wagner Jr., the company’s EVP, COO and CFO, reported a Form 4 transaction involving company common stock. On February 24, 2026, he had 1,744 shares of Vertex common stock disposed of in a transaction coded “F,” which represents payment of tax liability by delivering securities, at a price of $485.11 per share. After this tax-withholding disposition, Wagner directly owned 47,042 shares of Vertex common stock.
Vertex Pharmaceuticals executive Ourania Tatsis, EVP and Chief Regulatory & Quality Officer, reported two transactions in Vertex common stock. She completed an open-market sale of 260 shares at $486.35 per share under a company-approved Rule 10b5-1 trading plan. In a separate transaction, she disposed of 1,627 shares at $485.11 per share to cover tax obligations. After these transactions, she directly holds 46,763 shares of Vertex common stock.
Vertex Pharmaceuticals executive Amit Sachdev reported share sales and related tax withholding transactions. On February 25, 2026, he completed an open-market sale of 1,846 shares of common stock at $486.35 per share, leaving him with 55,570 directly held shares.
On February 24, 2026, he disposed of 1,518 shares of common stock at $485.11 per share to cover tax obligations by delivering shares. He also reported indirect holdings of 882 shares in a 401(k) plan and 9,301 shares held in a trust. The filing notes that the sale was made under a company-approved Rule 10b5-1 trading plan entered into on November 18, 2025.
Vertex Pharmaceuticals executive Duncan McKechnie reported multiple stock transactions. On February 25, 2026, he made open-market sales of 2,500 common shares at $486.35 per share and 2,410 shares at $489.00 per share.
On February 24, 2026, 873 shares were disposed of at $485.11 per share to cover tax obligations by delivering shares. After these transactions, he directly owned 17,559 Vertex common shares. The filing notes the sales were made under a company-approved Rule 10b5-1 trading plan entered on November 25, 2025.