VYNE CSO has 2,370 shares withheld for taxes

VYNE Therapeutics’ Chief Scientific Officer Stuart Iain had 2,370 shares of Common Stock withheld by the company to cover taxes related to vesting restricted stock units.

Rhea-AI Filing Summary

VYNE Therapeutics’ Chief Scientific Officer Stuart Iain had 2,370 shares of Common Stock withheld by the company to cover taxes related to vesting restricted stock units. The shares were valued at $0.6507 each in this tax-withholding disposition.

After this routine, non-market transaction, Iain directly holds 111,349 shares of VYNE Therapeutics Common Stock. The filing reflects compensation-related share withholding rather than an open-market purchase or sale.

Insider Trade Summary

Exercise Price or Tax Liability: 2,370 shares

Exercise Price or Tax Liability 1 txn

Insider Stuart Iain

Role CHIEF SCIENTIFIC OFFICER

Type	Security	Shares	Price	Value
Exercise Price or Tax Liability	Common Stock	2,370	$0.6507	$2K

Holdings After Transaction: Common Stock — 111,349 shares (Direct)

Footnotes (1)

1. F1. Represents shares that have been withheld by the Issuer to satisfy tax withholding requirements in connection with the vesting of restricted stock units.

Key Figures

Shares withheld for taxes: 2,370 shares Withholding price per share: $0.6507 per share Shares held after transaction: 111,349 shares

3 metrics

Shares withheld for taxes 2,370 shares Tax-withholding disposition on restricted stock unit vesting

Withholding price per share $0.6507 per share Value applied to withheld VYNE Common Stock

Shares held after transaction 111,349 shares Direct holdings of VYNE Common Stock following tax withholding

Key Terms

restricted stock units, tax withholding requirements, Common Stock, tax-withholding disposition

4 terms

restricted stock units financial

"in connection with the vesting of restricted stock units"

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

tax withholding requirements financial

"withheld by the Issuer to satisfy tax withholding requirements"

Common Stock financial

"security_title: "Common Stock""

Common stock represents ownership shares in a company, giving investors a stake in its success and a say in important decisions through voting rights. It is the most common type of stock traded on markets and can provide income through dividends, as well as potential for value growth. For investors, holding common stock means sharing in the company’s profits and risks.

tax-withholding disposition financial

"transaction_action: "tax-withholding disposition""

A tax-withholding disposition is an event or transaction—such as selling or transferring securities, exercising options, or receiving compensation—that triggers a requirement to hold back part of the payment and remit it to tax authorities. It matters to investors because it reduces the cash they receive immediately and can change the timing and amount of taxable income, like a cashier taking a portion of your sale proceeds to pay taxes before you get the rest.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What did VYNE (VYNE) officer Stuart Iain report in this Form 4 filing?

Stuart Iain reported a tax-related share disposition, where 2,370 VYNE Common Stock shares were withheld by the company. This occurred in connection with the vesting of restricted stock units and reflects compensation-related tax withholding rather than an open-market trade.

Was the VYNE (VYNE) Form 4 transaction a market sale of shares?

No, the transaction was not a market sale. The 2,370 shares were withheld by VYNE to satisfy tax withholding requirements tied to vesting restricted stock units. This is a routine administrative step, not an open-market decision to sell shares.

How many VYNE (VYNE) shares does Stuart Iain hold after the reported transaction?

After the tax-withholding disposition, Stuart Iain directly holds 111,349 shares of VYNE Therapeutics Common Stock. This post-transaction holding reflects his remaining equity position following the company’s withholding of 2,370 shares for restricted stock unit tax obligations.

What price per share was used for the VYNE (VYNE) tax-withholding shares?

The 2,370 withheld shares were valued at approximately $0.6507 per share. This value is used to determine the amount of stock delivered to satisfy tax obligations arising from the vesting of restricted stock units granted as part of equity compensation.

What does the tax-withholding code F mean in the VYNE (VYNE) Form 4?

Code F indicates a tax-withholding disposition, where shares are delivered to the issuer to pay taxes or exercise costs. In this case, 2,370 VYNE shares were withheld to satisfy tax withholding requirements on vesting restricted stock units awarded to the executive.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 07/02/2026 - 08:05 PM EDT Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Stuart Iain

(Last) (First) (Middle)

C/O VYNE THERAPEUTICS INC.

P.O. BOX 125

(Street)

STEWARTSVILLE NEW JERSEY 08886

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
VYNE Therapeutics Inc. [ VYNE ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	CHIEF SCIENTIFIC OFFICER

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
06/30/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	06/30/2026		F(1)		2,370	D	$0.6507	111,349	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Represents shares that have been withheld by the Issuer to satisfy tax withholding requirements in connection with the vesting of restricted stock units.

	/s/ Mutya Harsch, Attorney-in-Fact	07/02/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)