VYNE Therapeutics (VYNE) CSO covers taxes with 2,876 shares

Rhea-AI Filing Summary

VYNE Therapeutics Inc.'s Chief Scientific Officer Stuart Iain reported a routine tax-related share disposition. On the vesting of restricted stock units, 2,876 shares of common stock were withheld by the company to satisfy tax withholding requirements at an indicated value of $0.5975 per share. After this non-market transaction, he directly holds 112,363 common shares, so the withholding reflects only a small portion of his overall position.

Insider Trade Summary

1 transaction reported

Mixed 1 txn

Insider Stuart Iain

Role CHIEF SCIENTIFIC OFFICER

Type	Security	Shares	Price	Value
Tax Withholding	Common Stock	2,876	$0.5975	$2K

Holdings After Transaction: Common Stock — 112,363 shares (Direct)

Footnotes (1)

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Key Figures

Shares withheld for taxes: 2,876 shares Per-share value for withholding: $0.5975 per share Shares held after transaction: 112,363 shares +1 more

4 metrics

Shares withheld for taxes 2,876 shares Tax withholding on RSU vesting

Per-share value for withholding $0.5975 per share Assigned value for withheld common stock

Shares held after transaction 112,363 shares Direct common stock ownership post-withholding

Tax-withholding transactions 1 transaction, 2,876 shares Summary of tax withholding dispositions

Key Terms

restricted stock units, tax withholding requirements, withheld by the Issuer, tax-withholding disposition

4 terms

restricted stock units financial

"in connection with the vesting of restricted stock units."

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

tax withholding requirements financial

"withheld by the Issuer to satisfy tax withholding requirements"

withheld by the Issuer financial

"Represents shares that have been withheld by the Issuer"

tax-withholding disposition financial

"transaction_action": "tax-withholding disposition""

A tax-withholding disposition is an event or transaction—such as selling or transferring securities, exercising options, or receiving compensation—that triggers a requirement to hold back part of the payment and remit it to tax authorities. It matters to investors because it reduces the cash they receive immediately and can change the timing and amount of taxable income, like a cashier taking a portion of your sale proceeds to pay taxes before you get the rest.

Form 4 Insider Transactions: What Each Field Means →

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Stuart Iain

(Last) (First) (Middle)

C/O VYNE THERAPEUTICS INC.

P.O. BOX 125

(Street)

STEWARTSVILLE NEW JERSEY 08886

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
VYNE Therapeutics Inc. [ VYNE ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	CHIEF SCIENTIFIC OFFICER

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
03/31/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	03/31/2026		F(1)		2,876	D	$0.5975	112,363	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Represents shares that have been withheld by the Issuer to satisfy tax withholding requirements in connection with the vesting of restricted stock units.

	/s/ Mutya Harsch, Attorney-in-Fact	04/02/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What did VYNE (VYNE) Chief Scientific Officer Stuart Iain report in this Form 4?

Stuart Iain reported that 2,876 VYNE common shares were withheld to cover taxes on vesting restricted stock units. This was a non-market, tax-withholding disposition rather than an open-market sale, and he continues to hold 112,363 common shares directly.

Was the VYNE (VYNE) insider transaction an open-market sale of shares?

No, the transaction was not an open-market sale. The company withheld 2,876 common shares to satisfy tax withholding requirements tied to restricted stock unit vesting, a common administrative step when equity awards vest, rather than a discretionary share sale in the market.

How many VYNE (VYNE) shares were withheld for taxes in this filing?

The filing shows that 2,876 VYNE common shares were withheld to cover tax obligations on vesting restricted stock units. These shares were retained by the issuer for tax withholding, so they did not involve a market trade or cash sale by the insider.

How many VYNE (VYNE) shares does Stuart Iain hold after this tax withholding?

After the tax-withholding transaction, Stuart Iain directly owns 112,363 VYNE common shares. This indicates the withheld 2,876 shares represent only a small fraction of his overall holdings, and the filing mainly updates his post-vesting share balance.

What price per share is associated with the withheld VYNE (VYNE) shares?

The filing reports a value of $0.5975 per share for the 2,876 withheld common shares. This figure is used to calculate the tax-withholding amount when restricted stock units vest, rather than representing an open-market trade price set by a public sale.

What do the restricted stock units mentioned in the VYNE (VYNE) filing represent?

The restricted stock units represent equity awards that convert into common shares when vesting conditions are met. When they vested here, the company withheld 2,876 resulting shares to satisfy tax withholding, while the remaining vested shares increased the insider’s direct common share ownership.