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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
________________________
FORM 8-K
________________________
CURRENT REPORT
Pursuant to Section 13 or 15(d) of The
Securities Exchange Act of 1934
Date of Report (Date of earliest event
reported): November 13,
2026
________________________
Xenetic Biosciences,
Inc.
(Exact name of registrant as specified in charter)
| Nevada |
|
001-37937 |
|
45-2952962 |
(State or other jurisdiction
of incorporation) |
|
(Commission
File Number) |
|
(IRS Employer
Identification No.) |
| 945
Concord Street |
|
| Framingham, Massachusetts |
01701 |
| (Address of principal executive offices) |
(Zip Code) |
(781) 778-7720
(Registrant’s telephone number, including
area code)
Not Applicable
(Former name or former address, if changed since
last report)
Check the appropriate box below if the
Form 8-K is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see
General Instruction A.2. below):
☐ Written communications
pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
☒ Soliciting material
pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
☐ Pre-commencement
communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
☐ Pre-commencement
communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Securities registered pursuant to Section 12(b)
of the Act:
| Title of each class |
|
Trading Symbol(s) |
|
Name of each exchange on which registered |
| Common Stock, $0.001 par value per share |
|
XBIO |
|
The
Nasdaq Stock Market |
Indicate by check mark whether the registrant
is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities
Exchange Act of 1934 (17 CFR §240.12b-2).
Emerging growth company ☐
If an emerging growth company, indicate by check
mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting
standards provided pursuant to Section 13(a) of the Exchange Act. ☐
| Item 2.02. |
Results of Operations and Financial Condition. |
On November 13, 2026, Xenetic Biosciences, Inc.
(the “Company”) issued a press release announcing results for the three months ended September 30, 2026 and highlighting strategic
business updates.
The full text of the press release is furnished
as Exhibit 99.1 to this Current Report on Form 8-K and hereby incorporated in this Item 2.02 by reference. The information in this Item
2.02, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange
Act of 1934, as amended, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended,
except as shall be expressly set forth by specific reference in such filing.
FORWARD-LOOKING STATEMENTS
This Form 8-K, including the press release, contains
forward-looking statements that we intend to be subject to the safe harbor provisions of the Private Securities Litigation Reform Act
of 1995.
All statements contained in this press release
other than statements of historical facts may constitute forward-looking statements within the meaning of the federal securities laws.
These statements can be identified by words such as "expects," "plans," "projects," "will," "may,"
"anticipates," "believes," "should," "intends," "estimates," "remain," "focus",
"confidence in", "potential", "continues", "warrants", "provides", "opportunity", "aim"
and other words of similar meaning, This communication contains "forward-looking statements" within the meaning of the "safe
harbor" provisions of the Private Securities Litigation Reform Act of 1995, including but not limited to, express or implied statements
regarding the structure, timing and completion of the proposed share exchange transaction with Santersus AG (the “Proposed Transaction”),
including the combined company's listing on Nasdaq after closing of the Proposed Transaction, expectations regarding the ownership structure
of the combined company, the future operations of the combined company, the nature, strategy and focus of the combined company, the development
and commercial potential and potential benefits of NucleoCapture and Xenetic's DNase technology, anticipated clinical drug development
activities and related timelines, including the expected timing for data and other clinical results, the competitive landscape of the
combined company, the expected board composition of the combined company, and expectations regarding the combined company’s development
programs and potential catalysts; all statements regarding the status, target and aim of, and anticipated results from, the investigator-initiated
clinical study evaluating systemic recombinant human DNase in combination with anti-CD19 CAR T-cell therapy in patients with large B-cell
lymphoma at the Ichilov Center in Israel, including our expectations with respect to working with PeriNess and continued advancement
of the study, and anticipated treatments under the study; our focus on advancing innovative immuno-oncology technologies addressing difficult
to treat cancers, the DNase platform improving outcomes of existing treatments, including immunotherapies, by targeting neutrophil extracellular
traps (NETs), which are involved in cancer progression; and our focus on advancing our systemic DNase program into the clinic as an adjunctive
therapy for pancreatic carcinoma and locally advanced or metastatic solid tumors; and other statements that are not historical fact.
All statements other than statements of historical fact contained in this communication are forward-looking statements. These forward-looking
statements are made as of the date they were first issued, and were based on the then-current expectations, estimates, forecasts, and
projections, as well as the beliefs and assumptions of management. Forward-looking statements are subject to a number of risks and uncertainties,
many of which involve factors or circumstances that are beyond Xenetic, Santersus or the combined company's control. Actual results could
differ materially from those stated or implied in forward-looking statements due to a number of factors, including but not limited to
(i) the risk that the conditions to the closing of the Proposed Transaction are not satisfied, including the failure to timely obtain
stockholder approval for the transaction, if at all; (ii) uncertainties as to the timing of the consummation of the Proposed Transaction
and the ability of each of Xenetic and Santersus to consummate the Proposed Transaction; (iii) risks related to each parties' ability
to manage its operating expenses and its expenses associated with the Proposed Transaction pending closing; (iv) risks related to the
failure or delay in obtaining required approvals from any governmental or quasi-governmental entity necessary to consummate the Proposed
Transaction; (v) the risk that as a result of adjustments to the exchange ratio, Xenetic stockholders and Santersus stockholders could
own more or less of the combined company than is currently anticipated; (vi) risks related to the market price of Xenetic common stock
relative to the value suggested by the exchange ratio; (vii) unexpected costs, charges or expenses resulting from the Proposed Transaction;
(viii) potential adverse reactions or changes to business relationships resulting from the announcement or completion of the Proposed
Transaction; (ix) the uncertainties associated with Xenetic platform technologies, as well as risks associated with the clinical development
and regulatory approval of product candidates, including potential delays in the commencement, enrollment and completion of clinical
trials; (x) risks related to the inability of the combined company to obtain sufficient additional capital to continue to advance these
product candidates and its clinical programs; (xi) uncertainties in obtaining successful clinical results for product candidates and
unexpected costs that may result therefrom; (xii) risks related to the failure to realize any value from product candidates being developed
and anticipated to be developed in light of inherent risks and difficulties involved in successfully bringing product candidates to market;
(xiii) risks associated with the possible failure to realize certain anticipated benefits of the Proposed Transaction, including with
respect to future financial and operating results, (xiv) risks related to the inability of the combined company to maintain compliance
with Nasdaq listing requirements following closing of the Proposed Transaction, and the potential need for the combined company to effect
a reverse stock split in order to satisfy Nasdaq listing requirements; (xv) risks related to the combined company raising additional
working capital and financing its business; and (xvi) the other factors discussed under the heading "Risk Factors" in Xenetic's
most recent Annual Report on Form 10-K and other filings with the SEC, among others. Actual results and the timing of events could differ
materially from those anticipated in such forward-looking statements as a result of these risks and uncertainties. These and other risks
and uncertainties are more fully described in filings that Xenetic makes and will make with the Securities and Exchange Commission (“SEC”)
in connection with the Proposed Transaction, including Xenetic's Proxy Statement described below under "Additional Information and
Where to Find It." You should not place undue reliance on these forward-looking statements, which are made only as of the date hereof
or as of the dates indicated in the forward-looking statements. Xenetic, Santersus and the combined company expressly disclaims any obligation
or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change
in its expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based.
No Offer or Solicitation
This communication is not intended to and shall
not constitute an offer to subscribe for, buy or sell or the solicitation of an offer to subscribe for, buy or sell any securities, or
a solicitation of any vote or approval, nor shall there be any sale of, or offer to sell or buy, securities in any jurisdiction in which
such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction.
This communication is for informational purposes only. No offering of securities shall be made, except by means of a prospectus meeting
the requirements of Section 10 of the U.S. Securities Act of 1933, as amended, and otherwise in accordance with applicable law.
Additional Information and Where to Find It
This communication relates to the proposed acquisition
transaction involving Xenetic and Santersus and may be deemed to be solicitation material in respect of the Proposed Transaction. In connection
with the Proposed Transaction, Xenetic will file with the SEC a Proxy Statement and Registration Statement on Form S-1. Each party may
also file other documents regarding the Proposed Transaction with the SEC. Investors and security holders are urged to read carefully
the proxy statement, registration statement on Form S-1, and other relevant documents filed or will be filed with the SEC, as well as
any amendments or supplements thereto and any documents incorporated by reference therein, in their entirety if and when they become available
because they contain or will contain important information about the proposed transaction, related matters and the parties to the proposed
transaction.
Investors and security holders may obtain a free
copy of the Proxy Statement, the Registration Statement on Form S-1, and other relevant documents (if and when they become available)
that are or will be filed with the SEC for free at the SEC’s website at http://www.sec.gov. Copies of the documents (when they become
available) filed with the SEC by Xenetic Biosciences will be available free of charge on Xenetic’s website at www.xeneticbio.com.
Participants in the Solicitation
Xenetic, and its directors and executive officers,
and Santersus, and its directors and officers, may be deemed to be participants in the solicitation of proxies from the stockholders of
Xenetic in connection with the Proposed Transaction under the rules of the SEC. Information about the interests of these directors and
executive officers and other persons who may be deemed to be participants in the solicitation of stockholders of Xenetic in connection
with the Proposed Transaction and a description of their direct and indirect interests, by security holdings or otherwise, will be included
in the Proxy Statement related to the Proposed Transaction, which will be filed with the SEC. Additional information about Xenetic, the
directors and executive officers of Xenetic and their ownership of Xenetic common stock can also be found in its Annual Report on Form
10-K for the year ended December 31, 2025, as filed with the SEC on March 12, 2026, and amended on April 24, 2026, and its definitive
proxy statement, as filed with the SEC on October 31, 2025, and other documents subsequently filed by Xenetic with the SEC. Free copies
of these documents may be obtained as described above. To the extent holdings of Xenetic securities by its directors or executive officers
have changed since the amounts set forth in such documents, such changes have been or are expected to be reflected on Initial Statements
of Beneficial Ownership on Form 3 or Statements of Beneficial Ownership on Form 4 filed with the SEC. Additional information regarding
the identity of potential participants, and their direct or indirect interests, by security holdings or otherwise, will be included in
the Proxy Statement relating to the Proposed Transaction when it is filed with the SEC.
Item 9.01.
Financial Statements and Exhibits.
(d) Exhibits.
| Exhibit No. |
|
Description |
| |
|
|
| 99.1 |
|
Press Release dated November 13, 2026 pertaining to the financial results
of the Company for the three months ended September 30, 2026. |
| 104 |
|
Cover Page Interactive Data File (embedded within the Inline XBRL document). |
SIGNATURES
Pursuant to the requirements
of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto
duly authorized.
| |
XENETIC BIOSCIENCES, INC. |
| |
|
|
| |
By: |
/s/ James Parslow |
| Date: November 13, 2026 |
Name: |
James Parslow |
| |
Title: |
Interim Chief Executive Officer and Chief Financial Officer |
Exhibit 99.1

Xenetic Biosciences
Reports Third Quarter 2026 Financial Results and Highlights Strategic Business Updates
Proposed share exchange transaction expected
to create a multi-indication clinical stage company focused on targeting neutrophil extracellular traps (NETs)
Joint pipeline includes four first-in-class
programs, including pivotal-stage programs in sepsis and systemic lupus erythematosus (SLE), both of which have received FDA Breakthrough
Device Designation
Ongoing generation of translational data demonstrating
that DNase I enhanced antitumor activity across four CAR targets in preclinical models of leukemia, lymphoma, multiple myeloma and glioblastoma
First clinical evaluation of Xenetic’s
systemic DNase technology combined with CAR T-cell therapy in an investigator-initiated study conducted at Tel Aviv Sourasky University
Medical Center with initial efficacy data expected in Q2 2027
FRAMINGHAM,
MA – (November 13, 2026) – Xenetic Biosciences, Inc. (NASDAQ: XBIO) (“Xenetic”
or the “Company”), a biopharmaceutical company focused on advancing innovative immuno-oncology technologies addressing difficult
to treat cancers, today reported financial results for the third quarter ended September 30, 2026, and highlighted its proposed share
exchange transaction with Santersus AG ("Santersus"), which is expected to establish a Nasdaq-listed, clinical-stage company
with a differentiated pipeline targeting neutrophil extracellular traps (NETs) across multiple high-value therapeutic indications.
"This is a defining period for Xenetic as
we work toward completing a transaction that we believe has the potential to fundamentally transform the Company's clinical development
profile and long-term value proposition," said James Parslow, Interim Chief Executive Officer and Chief Financial Officer of Xenetic
Biosciences. "Santersus is expected to bring an established clinical-stage platform, two FDA Breakthrough Device Designations and
a pipeline targeting serious diseases with substantial unmet medical needs. Importantly, the proposed combined company would have multiple
development programs and potential catalysts, including an ongoing pivotal sepsis study, planned advancement in lupus and an anticipated
oncology clinical readout in 2027."
Mr. Parslow continued, "We believe the complementary
nature of NucleoCapture® and Xenetic's DNase platform provides a differentiated opportunity to address NETs through distinct mechanisms,
potentially expanding the therapeutic reach of the combined platform. Our focus remains on advancing the proposed transaction and positioning
the combined organization to execute against its development priorities and build sustainable stockholder value."
Third Quarter 2026 and Recent Strategic Highlights
| · | Initiated Clinical Evaluation of DNase I in Combination with CAR T-Cell Therapy: Announced the
first patient dosed in an investigator-initiated, Phase I (NCT07361224) clinical study evaluating systemic recombinant human DNase I in
combination with anti-CD19 CAR T-cell therapy in patients with large B-cell lymphoma (LBCL). The study is being conducted at Tel Aviv
Sourasky University Medical Center in Israel in collaboration with PeriNess Ltd., with initial efficacy data expected in the second quarter
of 2027. |
| · | Advanced Pre-Clinical Development Strategy in CAR T cell therapy: Research examines a self-reinforcing
niche of therapy resistance created by extracellular chromatin and NETs released during CAR T-cell killing and its reversal by DNase I. |
| · | Announced Definitive Exchange Agreement with Santersus AG: Entered into a definitive share exchange
agreement to, subject to Xenetic’s stockholder approval, acquire all of the outstanding share capital of Santersus AG in exchange
for newly issued shares of Xenetic in an all-stock transaction (the “Proposed Transaction”). The Proposed Transaction is expected
to create a Nasdaq-listed clinical-stage company focused on targeting neutrophil extracellular traps (NETs) across multiple therapeutic
indications. After closing, the combined company is expected to continue to trade on the Nasdaq Capital Market as Santersus Bio, Inc.,
under new ticker symbol “SNTS”. The Proposed Transaction has been unanimously approved
by the Board of Directors of Santersus. Xenetic’s Board of Directors – acting on the unanimous recommendation of its independent
Special Committee – has also approved the Proposed Transaction and recommends that Xenetic stockholders vote in favor of the Proposed
Transaction. The Proposed Transaction is expected to close in the first quarter of 2027, subject to approval by Xenetic stockholders,
the shares of Xenetic common stock issuable in the Proposed Transaction having been approved for listing on Nasdaq, the effectiveness
of a resale registration statement on Form S-1 to be filed with the U.S. Securities and Exchange Commission (“SEC”), and the
satisfaction or waiver of other customary closing conditions. |
Summary of Financial Results for Third Quarter
2026
Royalty revenue for the three months ended
September 30, 2026 decreased approximately 29% to approximately $0.7 million, compared to approximately $1.0 million for the comparable
prior-year period. The decrease was primarily attributable to positive royalty adjustments recognized from certain countries during the
third quarter of 2025 under the Company's sublicense agreement with Takeda Pharmaceutical Co. Ltd.
Research and development expenses for the
three months ended September 30, 2026 decreased approximately 31% to approximately $0.5 million, compared to approximately $0.8 million
for the comparable prior-year period, primarily due to lower manufacturing development costs.
General and administrative expenses for
the three months ended September 30, 2026 increased approximately 138% to approximately $1.9 million, compared to approximately $0.8 million
for the comparable quarter of 2025. The increase was primarily attributable to higher legal and financial advisory expenses associated
with the Proposed Transaction.
Net loss for the quarter ended September
30, 2026 was approximately $1.7 million, or $0.72 per basic and diluted share, compared to approximately $0.5 million, or $0.33 per basic
and diluted share, for the same period in 2025.
Cash and cash equivalents totaled approximately
$5.8 million as of September 30, 2026, compared to approximately $7.9 million as of December 31, 2025.
About Xenetic Biosciences
Xenetic Biosciences, Inc. is a biopharmaceutical
company focused on advancing innovative immuno-oncology technologies addressing difficult to treat cancers. The Company's proprietary
DNase technology is designed to improve outcomes of existing treatments, including immunotherapies, by targeting neutrophil extracellular
traps (NETs), which are involved in cancer progression. Xenetic is currently focused on advancing its systemic DNase program into the
clinic as an adjunctive therapy for pancreatic carcinoma and locally advanced or metastatic solid tumors.
For more information, please visit the Company's website at www.xeneticbio.com and
connect on X, LinkedIn,
and Facebook.
Forward-Looking Statements
This press release contains forward-looking statements
that we intend to be subject to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. All statements contained
in this press release other than statements of historical facts may constitute forward-looking statements within the meaning of the federal
securities laws. These statements can be identified by words such as "expects," "plans," "projects," "will,"
"may," "anticipates," "believes," "should," "intends," "estimates," "remain,"
"focus", "confidence in", "potential", "continues", "warrants", "provides",
"opportunity", "aim" and other words of similar meaning, including but not limited to, express or implied statements
regarding the structure, timing and completion of the Proposed Transaction, including the combined company's listing on Nasdaq after closing
of the Proposed Transaction, expectations regarding the ownership structure of the combined company, the future operations of the combined
company, the nature, strategy and focus of the combined company, the development and commercial potential and potential benefits of NucleoCapture
and Xenetic's DNase technology, anticipated clinical drug development activities and related timelines, including the expected timing
for data and other clinical results, the competitive landscape of the combined company, the expected board composition of the combined
company, and expectations regarding the combined company’s development programs and potential catalysts; all statements regarding
the status, target and aim of, and anticipated results from, the investigator-initiated clinical study evaluating systemic recombinant
human DNase in combination with anti-CD19 CAR T-cell therapy in patients with LBCL at the Tel Aviv Sourasky University Medical Center
in Israel, including our expectations with respect to working with PeriNess and continued advancement of the study and anticipated treatments
under the study; our focus on advancing innovative immuno-oncology technologies addressing difficult to treat cancers, the DNase platform
improving outcomes of existing treatments, including immunotherapies, by targeting neutrophil extracellular traps (NETs), which are involved
in cancer progression; and our focus on advancing our systemic DNase program into the clinic as an adjunctive therapy for pancreatic carcinoma
and locally advanced or metastatic solid tumors; and other statements that are not historical fact. All statements other than statements
of historical fact contained in this communication are forward-looking statements. These forward-looking statements are made as of the
date they were first issued, and were based on the then-current expectations, estimates, forecasts, and projections, as well as the beliefs
and assumptions of management. Forward-looking statements are subject to a number of risks and uncertainties, many of which involve factors
or circumstances that are beyond Xenetic, Santersus or the combined company's control. Actual results could differ materially from those
stated or implied in forward-looking statements due to a number of factors, including but not limited to (i) the risk that the conditions
to the closing of the Proposed Transaction are not satisfied, including the failure to timely obtain stockholder approval for the transaction,
if at all; (ii) uncertainties as to the timing of the consummation of the Proposed Transaction and the ability of each of Xenetic and
Santersus to consummate the Proposed Transaction; (iii) risks related to each parties' ability to manage its operating expenses and its
expenses associated with the Proposed Transaction pending closing; (iv) risks related to the failure or delay in obtaining required approvals
from any governmental or quasi-governmental entity necessary to consummate the Proposed Transaction; (v) the risk that as a result of
adjustments to the exchange ratio, Xenetic stockholders and Santersus stockholders could own more or less of the combined company than
is currently anticipated; (vi) risks related to the market price of Xenetic common stock relative to the value suggested by the exchange
ratio; (vii) unexpected costs, charges or expenses resulting from the Proposed Transaction; (viii) potential adverse reactions or changes
to business relationships resulting from the announcement or completion of the Proposed Transaction; (ix) the uncertainties associated
with Xenetic platform technologies, as well as risks associated with the clinical development and regulatory approval of product candidates,
including potential delays in the commencement, enrollment and completion of clinical trials; (x) risks related to the inability of the
combined company to obtain sufficient additional capital to continue to advance these product candidates and its clinical programs; (xi)
uncertainties in obtaining successful clinical results for product candidates and unexpected costs that may result therefrom; (xii) risks
related to the failure to realize any value from product candidates being developed and anticipated to be developed in light of inherent
risks and difficulties involved in successfully bringing product candidates to market; (xiii) risks associated with the possible failure
to realize certain anticipated benefits of the Proposed Transaction, including with respect to future financial and operating results;
(xiv) risks related to the inability of the combined company to maintain compliance with Nasdaq listing requirements following closing
of the Proposed Transaction, and the potential need for the combined company to effect a reverse stock split in order to satisfy Nasdaq
listing requirements; (xv) risks related to the combined company raising additional working capital and financing its business; and (xvi)
the other factors discussed under the heading "Risk Factors" in Xenetic's most recent Annual Report on Form 10-K and other filings
with the SEC, among others. Actual results and the timing of events could differ materially from those anticipated in such forward-looking
statements as a result of these risks and uncertainties. These and other risks and uncertainties are more fully described in filings that
Xenetic makes and will make with the SEC in connection with the Proposed Transaction, including Xenetic's Proxy Statement described below
under "Additional Information and Where to Find It." You should not place undue reliance on these forward-looking statements,
which are made only as of the date hereof or as of the dates indicated in the forward-looking statements. Xenetic, Santersus and the combined
company expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements
contained herein to reflect any change in its expectations with regard thereto or any change in events, conditions or circumstances on
which any such statements are based.
No Offer or Solicitation
This communication is not intended to and shall not constitute an offer
to subscribe for, buy or sell or the solicitation of an offer to subscribe for, buy or sell any securities, or a solicitation of any vote
or approval, nor shall there be any sale of, or offer to sell or buy, securities in any jurisdiction in which such offer, solicitation
or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction. This communication
is for informational purposes only. No offering of securities shall be made, except by means of a prospectus meeting the requirements
of Section 10 of the U.S. Securities Act of 1933, as amended, and otherwise in accordance with applicable law.
Additional Information and Where to Find It
This communication relates to the proposed acquisition transaction
involving Xenetic and Santersus and may be deemed to be solicitation material in respect of the Proposed Transaction. In connection with
the Proposed Transaction, Xenetic will file with the SEC a Proxy Statement and Registration Statement on Form S-1. Each party may also
file other documents regarding the Proposed Transaction with the SEC. Investors and security holders are urged to read carefully the proxy
statement, registration statement on Form S-1, and other relevant documents filed or will be filed with the SEC, as well as any amendments
or supplements thereto and any documents incorporated by reference therein, in their entirety if and when they become available because
they contain or will contain important information about the proposed transaction, related matters and the parties to the proposed transaction.
Investors and security holders may obtain a free copy of the Proxy
Statement, the Registration Statement on Form S-1, and other relevant documents (if and when they become available) that are or will be
filed with the SEC for free at the SEC’s website at http://www.sec.gov. Copies of the documents (when they become available) filed
with the SEC by Xenetic Biosciences will be available free of charge on Xenetic’s website at www.xeneticbio.com.
Participants in the Solicitation
Xenetic, and its directors and executive officers, and Santersus, and
its directors and officers, may be deemed to be participants in the solicitation of proxies from the stockholders of Xenetic in connection
with the Proposed Transaction under the rules of the SEC. Information about the interests of these directors and executive officers and
other persons who may be deemed to be participants in the solicitation of stockholders of Xenetic in connection with the Proposed Transaction
and a description of their direct and indirect interests, by security holdings or otherwise, will be included in the Proxy Statement related
to the Proposed Transaction, which will be filed with the SEC. Additional information about Xenetic, the directors and executive officers
of Xenetic and their ownership of Xenetic common stock can also be found in its Annual Report on Form 10-K for the year ended December
31, 2025, as filed with the SEC on March 12, 2026, and amended on April 24, 2026, and its definitive proxy statement, as filed with the
SEC on October 31, 2025, and other documents subsequently filed by Xenetic with the SEC. Free copies of these documents may be obtained
as described above. To the extent holdings of Xenetic securities by its directors or executive officers have changed since the amounts
set forth in such documents, such changes have been or are expected to be reflected on Initial Statements of Beneficial Ownership on Form
3 or Statements of Beneficial Ownership on Form 4 filed with the SEC. Additional information regarding the identity of potential participants,
and their direct or indirect interests, by security holdings or otherwise, will be included in the Proxy Statement relating to the Proposed
Transaction when it is filed with the SEC.
Contact:
JTC Team, LLC
Jenene Thomas
(908) 824-0775
xbio@jtcir.com