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Zymeworks Inc. reports a Schedule 13G filing showing Perceptive-linked holders beneficially own 3,974,579 shares of Common Stock. The filing states this equals 5.4% of the class based on 73,749,607 shares outstanding as of February 26, 2026. Perceptive Life Sciences Master Fund directly holds the shares; Perceptive Advisors and Joseph Edelman are reported as investment manager and managing member, respectively.
Zymeworks Inc. reported that officer Adam Schayowitz received new equity awards as part of his compensation. On April 9, 2026, he was granted stock options for 70,000 shares of common stock at an exercise price of $27.35 per share, expiring on April 8, 2036. These options vest 25% on the first anniversary of the grant and the rest in 36 monthly installments.
He also received 47,000 restricted stock units that vest in four equal annual installments, plus up to 76,000 performance stock units. The performance units can be earned between 50% and 200% of a 38,000-unit target based on cumulative total shareholder return over a three-year period ending on January 12, 2029, subject to continued service and specific TSR goals.
Zymeworks Inc. granted equity-based compensation to EVP and Chief Business Officer Scott Platshon. He received stock options for 70,000 shares of common stock at an exercise price of $27.35 per share, expiring on April 8, 2036, which vest 25% after one year and monthly thereafter.
Platshon was also granted 47,000 restricted stock units that vest in four equal annual installments, each RSU delivering one share of common stock upon vesting. In addition, he received 76,000 performance stock units, representing the maximum number that may be earned based on cumulative total shareholder return goals over a three-year performance period ending on January 12, 2029, with 50%–200% of a 38,000-unit target earnable depending on performance.
Zymeworks Inc. disclosed initial equity holdings for executive Adam Schayowitz. He holds stock options covering 167,000 shares of common stock with an exercise price of $16.92 per share, expiring on October 8, 2035. These options were granted on October 9, 2025 and vest 25% on the first anniversary of the grant date, with the remaining 75% vesting in 36 equal monthly installments thereafter.
Schayowitz also holds 111,111 restricted stock units (RSUs) granted on October 9, 2025. These RSUs vest in three equal annual installments beginning October 9, 2026. Each RSU represents the contingent right to receive one share of Zymeworks common stock upon vesting.
Zymeworks Inc. executive Platshon Scott, EVP and Chief Business Officer, reported initial equity awards in a Form 3. The filing lists stock options covering 167,000 shares of common stock at an exercise price of $22.99 per share, expiring November 17, 2035, plus 111,111 restricted stock units. The options vest 25% on the first anniversary of the November 18, 2025 grant and the remainder in 36 equal monthly installments, while the RSUs vest in three equal annual installments beginning November 18, 2026, with each RSU representing the right to receive one share of common stock upon vesting.
Zymeworks Inc. reported that EVP and Chief Financial Officer Kristin Stafford received new equity compensation awards. She was granted stock options for 178,000 shares of common stock at an exercise price of $25.84 per share, expiring on April 5, 2036. These options vest 25% on the first anniversary of the grant date, with the remaining 75% vesting in 36 equal monthly installments thereafter.
Stafford also received two restricted stock unit grants. One award covers 119,000 RSUs, vesting in four equal annual installments beginning on the first anniversary of the grant date. The other covers 50,000 RSUs, vesting in three equal annual installments starting on the first anniversary. Each RSU converts into one share of common stock upon vesting, and the filing shows no open-market purchases or sales.
Zymeworks Inc. executive vice president and chief financial officer Kristin Stafford filed an initial Form 3 indicating she currently has no securities beneficially owned in the company. The filing lists both common and derivative securities as having zero shares, reflecting no direct reportable ownership as of the reported date.
Zymeworks Inc. appointed Kristin Stafford, age 44, as Executive Vice President and Chief Financial Officer, effective April 1, 2026. She becomes the company’s principal financial and principal accounting officer. Stafford previously held senior finance and accounting roles at Royalty Pharma, BioPharma Credit, Ernst & Young, iHeartMedia, and Deloitte and serves on Novocure’s board.
She entered into an employment agreement with Zymeworks Biopharmaceuticals Inc. with no fixed term, including change-in-control "parachute" protections structured to avoid excise tax without any tax gross-up from the company. Kenneth Galbraith ceased serving as interim CFO on the start date but continues as Chair, President, and Chief Executive Officer.
Zymeworks Inc. insider transactions were reported: director/officer Jeffrey T. L. Smith disclosed open-market dispositions and planned sales of common stock. The filing shows two sales: 10,538 shares on 01/05/2026 for $264,471.13 and 9,310 shares on 01/12/2026 for $211,090.28. The filing also lists securities to be sold on 03/06/2026 tied to an exercise of options (220,625 shares) and multiple upcoming restricted stock unit vestings (9,462; 8,356; 8,890 shares) on 01/05/2026 and 01/12/2026 described as compensation-related transactions.
Zymeworks Inc. has entered into a $250 million non-recourse royalty-backed note financing with Royalty Pharma, using 30% of future worldwide tiered royalties on Ziihera (zanidatamab-hrii) from Jazz and BeOne as repayment collateral. The funding is structured through a special-purpose subsidiary that sold a 30% royalty interest and simultaneously borrowed $250 million under a term loan maturing on December 31, 2042.
The total amount payable under the loan is about $412.5 million if fully repaid on or before December 31, 2033, or approximately $481.3 million if repaid by final maturity, inclusive of interest, premiums, fees and other amounts. Zymeworks will retain 70% of Ziihera royalties during the repayment period, with full royalty rights reverting once Royalty Pharma’s capped return is reached, and it keeps all regulatory and commercial milestone payments, including up to $1.5 billion in potential remaining milestones tied to approvals and sales.
The loan is secured only by the subsidiary’s royalty assets and related equity interests, and Royalty Pharma has no recourse to other Zymeworks or Zymeworks BC assets under the agreement. The arrangements include customary covenants, restrictions on modifying key collaboration agreements for Ziihera, and events of default tied to termination of those agreements or a change of control of the company.