Welcome to our dedicated page for Maze Therapeutics SEC filings (Ticker: MAZE), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Maze Therapeutics, Inc. (Nasdaq: MAZE) SEC filings page brings together the company’s public regulatory disclosures, offering a detailed view of how this clinical-stage biopharmaceutical company reports its activities to U.S. regulators. Maze focuses on small molecule precision medicines for kidney and metabolic diseases, and its filings provide context on both its scientific programs and its capital markets activity.
Maze’s filings include current reports on Form 8-K, which the company uses to announce material events such as quarterly financial results, leadership changes, and financing transactions. For example, Maze has filed 8-Ks to furnish press releases on second and third quarter financial results, to disclose an oversubscribed private placement of common stock and pre-funded warrants, and to document the appointments of a new chief financial officer and a new chairman of the board.
Investors can also review registration statements, such as the company’s Form S-1, which describes Maze’s business, risk factors, and the resale of shares issued in its 2025 private placement. The S-1 outlines Maze’s focus on human genetics, its Compass platform, and its lead programs MZE829 and MZE782, while also confirming its status as an emerging growth company and smaller reporting company.
Through Stock Titan, these filings are updated in near real time from the SEC’s EDGAR system, and AI-powered summaries help explain the key points of lengthy documents. Users can quickly understand what a particular 8-K, S-1, or other filing means for the company without reading every page. Where applicable, filings related to equity financings, registration rights, and governance changes are highlighted so investors can track dilution, board composition, and executive appointments.
For MAZE, monitoring SEC filings is especially relevant for understanding clinical development disclosures, financing capacity, and risk factors associated with its kidney and metabolic disease programs. This page serves as a central resource for reviewing those official documents alongside concise AI-generated explanations.
Maze Therapeutics, Inc. director and CEO Jason V. Coloma reported indirect open-market sales of company common stock by two family trusts associated with him. On June 1, 2026, the Coloma Family Trust sold 6,090 shares at a weighted average price of $26.1965 per share, leaving it with 344,897 shares. The Coloma 2021 Irrevocable Trust sold 553 shares at a weighted average price of $26.2412, leaving it with 27,970 shares. A footnote states these transactions were carried out under a pre-arranged Rule 10b5-1 trading plan adopted on February 6, 2026, indicating they were scheduled in advance rather than timed discretionarily.
Maze Therapeutics, Inc. President, R&D & CMO Harold Bernstein exercised stock options for 14,853 shares of common stock at an exercise price of $10.42 per share, then sold all 14,853 shares in open-market transactions at weighted average prices of $25.57 and $26.36 per share. These trades were executed under a pre-arranged Rule 10b5-1 trading plan, and he reported no directly held common shares afterward while retaining 207,554 stock options following the option exercise.
Maze Therapeutics, Inc. chief business officer Atul Dandekar reported option exercises and related share sales. On May 29, 2026, he exercised stock options to acquire 7,500 shares of common stock at $10.42 per share and then sold 7,500 shares in open-market transactions at a weighted average price of $26.3405 per share. The sale was carried out under a pre-arranged Rule 10b5-1 trading plan adopted on September 29, 2025. After these transactions, he directly owned 24,808 shares of Maze Therapeutics common stock.
The Coloma trusts reported Rule 144 sales of MAZE common stock. The filing lists multiple dispositions by related trusts on including 116 shares on , 2,478 shares on , 1,822 shares on , 4,504 shares on , and 25,582 shares on , with corresponding gross proceeds shown.
Maze Therapeutics, Inc. director and CEO Jason V. Coloma reported indirect open-market sales of 32,564 shares of common stock, executed on May 22, 2026 and May 26, 2026.
The sales were made by the Coloma Family Trust and The Coloma 2021 Irrevocable Trust, where Coloma and his spouse serve as co-trustees. Reported prices were weighted averages around $26.00 per share, across multiple trades within narrow price ranges.
Following the latest transactions, the Coloma Family Trust held 350,987 shares and The Coloma 2021 Irrevocable Trust held 28,523 shares of Maze Therapeutics common stock. One of the transactions was carried out under a pre-arranged Rule 10b5-1 trading plan adopted on February 6, 2026, indicating a scheduled selling program rather than purely discretionary timing.
Maze Therapeutics, Inc. reported that Amy Bachrodt, its Senior Vice President of Finance, has given notice that she will resign effective June 1, 2026. The company states her resignation is not due to any disagreement regarding operations, policies, practices, or financial reporting. Following her departure, Chief Financial Officer Misbah Tahir will also serve as the company’s principal accounting officer, consolidating financial leadership under the CFO role.
Maze Therapeutics, Inc. director and Chief Executive Officer Jason V. Coloma reported open-market sales of common stock executed by family trusts associated with him. On May 15, 2026, The Coloma 2021 Irrevocable Trust sold 116 shares and the Coloma Family Trust sold 1,822 shares, each at $26.00 per share, for a total of 1,938 shares sold.
After these sales, the Coloma Family Trust held 381,073 shares of Maze Therapeutics common stock and The Coloma 2021 Irrevocable Trust held 31,001 shares. The transactions were carried out under a pre-arranged Rule 10b5-1 trading plan adopted by Coloma.
Maze Therapeutics, Inc. President, R&D & CMO Harold Bernstein reported an exercise-and-sell transaction in Common Stock. On May 14, 2026, he exercised stock options to acquire 15,000 shares at $10.42 per share, then sold the same 15,000 shares in open-market transactions at a weighted average price of $26.2236 per share, with individual sale prices ranging from $25.77 to $26.44. These trades were made under a pre-arranged Rule 10b5-1 trading plan adopted on September 29, 2025. After the sale, he reported holding no Common Stock directly, while retaining 222,407 stock options with a $10.42 exercise price expiring on October 26, 2032.
MAZE submitted a Rule 144 notice reporting proposed sales of Common shares, listing specific lots and dates. The filing lists numeric entries including 34502, 895,326.90, 55,345,261 and lot counts 2,594 and 31,908, and includes an expiration or related date of 05/15/2026.
The notice identifies transfers described as Gift with a named transferee, Jason Coloma, and references brokerage placement at UBS Financial Services Inc. on Eleven Madison Avenue. The filing appears to be an administrative Rule 144 disclosure of resale activity rather than a primary offering.
Janus Henderson Group plc reports beneficial ownership of 2,858,876 shares of Maze Therapeutics, Inc. common stock, representing 5.8% of the class as of 03/31/2026. The filing states the holdings are held across Janus Henderson–managed portfolios, with shared voting and dispositive power of 2,858,876 shares and no sole voting or dispositive power. The filing notes the Asset Managers exercise voting discretion for client accounts and disclaim rights to dividends or sale proceeds tied to those accounts. The signature on the amendment is dated 5/15/2026.