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Maze Therapeutics, Inc. (MAZE) Financials

MAZE
FY2025 annual
Net Income -$131.1M -351.0% YoY
EPS (Diluted) -$3.05 YoY not available
Free Cash Flow -$112.7M -250.7% YoY
Operating Cash Flow -$111.9M -247.4% YoY
Market Cap $1.5B as of Oct 17, 2026
Price / Sales n/m no revenue reported
Price / Earnings n/m net loss, so no earnings multiple, FY2025
Price / Book 3.4x on $453.1M equity, Q2 FY2026

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Oct 17, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q2 FY2026, filed Aug 11, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the MAZE SEC filings page.

This page shows Maze Therapeutics, Inc. (MAZE) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 2 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI MAZE FY2025

Maze shifted from reported profitability to cash-backed losses while financing reshaped a formerly liability-heavy balance sheet.

The move from 2024 net income of $52.2M and operating cash flow of $76.0M to a 2025 net loss of $131.1M and operating cash flow of -$111.9M indicates that the earnings reversal was accompanied by a comparable cash reversal, not merely an accounting effect. Cash conversion tracked earnings in both periods, although 2025 free cash flow of -$112.7M shows that investment spending added little to the cash deficit.

The balance sheet was materially reconfigured: liabilities fell from $551.7M in FY2024 to $42.2M in FY2025, while equity moved from -$311.2M to $355.0M. That combination points to a major capitalization change rather than ordinary operating improvement, and it leaves debt-to-equity at a comparatively modest 0.1x in FY2025.

Liquidity is concentrated in current assets: the current ratio rose from 9.8x to 15.5x, while reported financing cash flow was $275.3M against operating cash flow of -$111.9M. The 38.6 months of reported outflow therefore reflects the balance and financing structure at year-end, not internally generated cash from operations.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Financial health score not available

Maze Therapeutics, Inc. does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.

Piotroski F-Score Partial
2/6

Maze Therapeutics, Inc. passes 2 of 6 computable financial strength tests (3 of the nine could not be computed from available data). 1 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass.

Earnings Quality No Cash Backing
N/A

Maze Therapeutics, Inc. reported a net loss of $131.1M while operations used $111.9M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

EBITDA
-$47.6M
YoY-33.0%
QoQ-82.5%

Maze Therapeutics, Inc.'s EBITDA was -$47.6M in Q2 2026, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 33.0% from the same quarter a year earlier. Against the prior quarter it is down 82.5%.

Net Income
-$44.7M
YoY-32.8%
QoQ-84.8%

Maze Therapeutics, Inc. reported -$44.7M in net income in Q2 2026. This represents a decrease of 32.8% from the same quarter a year earlier. Against the prior quarter it is down 84.8%.

EPS (Diluted)
-$0.76
YoY+1.3%
QoQ-68.9%

Maze Therapeutics, Inc. earned -$0.76 per diluted share (EPS) in Q2 2026. This represents an increase of 1.3% from the same quarter a year earlier. Against the prior quarter it is down 68.9%.

Revenue

Not reported for Q2 2026.

Cash & Balance Sheet

Free Cash Flow
-$15.2M
YoY+50.2%
QoQ+61.3%

Maze Therapeutics, Inc. recorded an outflow of $15.2M in free cash flow in Q2 2026, representing a cash shortfall after capex. This represents an increase of 50.2% from the same quarter a year earlier. Against the prior quarter it is up 61.3%.

Cash & Debt
$202.6M
YoY-23.4%
QoQ+2.0%

Maze Therapeutics, Inc. held $202.6M in cash against $39.0M in long-term debt as of Q2 2026.

Shares Outstanding
56M
YoY+26.7%
QoQ+0.4%

Maze Therapeutics, Inc. had 56M shares outstanding in Q2 2026. This represents an increase of 26.7% from the same quarter a year earlier. Against the prior quarter it is up 0.4%.

Dividends Per Share

Not reported for Q2 2026.

Margins & Returns

Return on Equity
-9.9%
YoY+3.0pp
QoQ-2.8pp

Maze Therapeutics, Inc.'s ROE was -9.9% in Q2 2026, measuring profit generated per dollar of shareholder equity. This is up 3.0 percentage points from the same quarter a year earlier. Against the prior quarter it is down 2.8 percentage points.

Gross Margin

Not reported for Q2 2026.

Operating Margin

Not reported for Q2 2026.

Net Margin

Not reported for Q2 2026.

Capital Allocation

R&D Spending
$34.9M
YoY+24.3%
QoQ+2.3%

Maze Therapeutics, Inc. invested $34.9M in research and development in Q2 2026. This represents an increase of 24.3% from the same quarter a year earlier. Against the prior quarter it is up 2.3%.

Capital Expenditures
$107K
YoY-72.8%
QoQ+15.1%

Maze Therapeutics, Inc. invested $107K in capex in Q2 2026, funding long-term assets and infrastructure. This represents a decrease of 72.8% from the same quarter a year earlier. Against the prior quarter it is up 15.1%.

Share Buybacks

Not reported for Q2 2026.

MAZE Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

MAZE quarterly income statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
RevenueN/A$20.0MN/AN/A$0-100.0%N/AN/A$2.5M
R&D Expenses$34.9M+24.3%$34.1M+23.8%N/A$25.2M+26.9%$28.1M+43.8%$27.6M+26.1%N/A$19.9M
SG&A Expenses$13.1M+56.5%$12.4M+58.6%N/A$7.8M+13.1%$8.4M+41.8%$7.8M+27.4%N/A$6.9M
Operating Income-$48.0M-31.7%-$26.6M+25.0%N/A-$33.0M-36.1%-$36.5M-126.1%-$35.4M-26.4%N/A-$24.2M
EBITDA-$47.6M-33.0%-$26.1M+24.8%N/A-$32.4M-38.2%-$35.8M-125.5%-$34.7M-28.3%N/A-$23.4M
Interest Expense$931K$866KN/AN/AN/AN/AN/AN/A
Income TaxN/AN/AN/A$0+100.0%$0-100.0%N/AN/A-$279K
Net Income-$44.7M-32.8%-$24.2M+26.2%N/A-$30.1M-21.6%-$33.7M-124.2%-$32.8M-0.9%N/A-$24.8M
EPS (Basic)-$0.76+1.3%-$0.45+60.9%-$0.60+71.0%-$0.66+93.6%-$0.77-113.0%-$1.15+91.7%-$2.07-$10.25
EPS (Diluted)-$0.76+1.3%-$0.45-$0.60-$0.66-$0.77-123.9%-$1.15-$1.42-$10.25
Diluted Shares (Avg)59M+34.7%54MN/A46M44M+915.2%29MN/A2M

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.

MAZE Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

MAZE quarterly balance sheet
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Total Assets$531.6M+75.2%$419.7M+26.1%$397.1M+65.1%$422.1M$303.5M$332.8M$240.5MN/A
Current Assets$420.4M+55.1%$379.8M+26.7%$349.7M+73.4%$391.3M$271.1M$299.7M$201.7MN/A
Cash & Equivalents$202.6M-23.4%$198.8M-32.5%$189.2M-3.8%$316.8M+111.7%$264.5M+51.1%$294.4M+880.5%$196.8M$149.6M
Short-Term Investments$208.4M$153.6M$152.7M$67.2M$0$0$0$0
Accounts ReceivableN/A$20.0MN/AN/AN/AN/AN/AN/A
Long-Term Investments$83.8M$10.6M$18.1M$0$0$0$0$0
Total Liabilities$78.5M+90.2%$78.0M+91.3%$42.2M-92.4%$42.6M$41.3M$40.8M$551.7MN/A
Current Liabilities$23.0M+15.4%$21.2M+14.1%$22.6M+9.1%$22.1M$19.9M$18.6M$20.7MN/A
Non-Current Liabilities$55.5M+159.8%$56.8M+156.3%$19.6M-96.3%$20.5M$21.4M$22.2M$531.1MN/A
Long-Term Debt$39.0M$38.8MN/AN/AN/AN/AN/AN/A
Total Equity$453.1M+72.8%$341.7M+17.0%$355.0M+214.1%$379.4M+233.4%$262.2M+199.9%$292.1M+172.4%-$311.2M-$284.5M
Retained Earnings-$558.5M-31.4%-$513.8M-31.3%-$489.5M-36.6%-$455.0M-$424.9M-$391.2M-$358.4MN/A

Not reported in any period shown, so not listed: Inventory, Goodwill.

MAZE Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

MAZE quarterly cash flow statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Cash Flow-$15.1M+49.9%-$39.1M-32.5%-$27.7M-23.5%-$24.6M-6.2%-$30.1M-120.7%-$29.5M-25.9%-$22.5M-$23.2M
Depreciation & Amortization$391K-39.8%$444K-35.1%$499K-29.2%$571K-27.5%$649K-24.0%$684K-28.0%$705K$788K
Stock-Based Compensation$9.2M+183.8%$7.1M+120.4%N/A$3.9M+64.9%$3.2M+51.1%$3.2M+39.7%N/A$2.3M
Capital Expenditures$107K-72.8%$93K-68.9%$34K-94.4%$68K-34.0%$393K+145.6%$299K+7.2%$605K$103K
Free Cash Flow-$15.2M+50.2%-$39.2M-31.5%-$27.8M-20.4%-$24.7M-6.0%-$30.4M-121.0%-$29.8M-25.7%-$23.1M-$23.3M
Investing Cash Flow-$128.5M-32598.7%$6.3M+2198.7%-$103.4M-16988.8%-$66.9M-64835.0%-$393K-145.6%-$299K-7.2%-$605K-$103K
Financing Cash Flow$147.4M+23990.8%$42.4M-66.7%$3.6M-94.9%$143.8M+6786.4%$612K+297.4%$127.4M+418.2%$70.3M-$2.1M

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

MAZE Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

MAZE quarterly financial ratios
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating MarginN/A-132.8%N/AN/AN/AN/AN/A-969.2%
Net MarginN/A-121.0%N/AN/AN/AN/AN/A-990.1%
Return on Equity-9.9%+3.0pp-7.1%+4.1ppN/A-7.9%-12.8%-11.2%N/AN/A
Return on Assets-8.4%+2.7pp-5.8%+4.1ppN/A-7.1%-11.1%-9.8%N/AN/A
Current Ratio18.31+4.7x17.88+1.8x15.50+5.7x17.7013.6316.109.76N/A
Debt-to-Equity0.09-0.1x0.110.0x0.120.110.160.14N/AN/A
Asset TurnoverN/A0.05N/AN/A0.00N/AN/AN/A
FCF MarginN/A-196.0%N/AN/AN/AN/AN/A-932.3%

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
Maze Therapeutics, Inc. MAZE FY2025 N/A -$131.1M N/A $1.5B —
Rapport Therapeutics, Inc. RAPP FY2025 N/A -$111.5M N/A $1.3B —
Oric Pharmaceuticals, Inc. ORIC FY2025 N/A -$129.5M N/A $1.3B —
Enliven Therapeutics, Inc. ELVN FY2025 N/A -$103.7M N/A $2.7B —
Wave Life Sciences Ltd. WVE FY2025 $42.7M -$204.4M N/A $616.8M 48/100
Sionna Therapeutics, Inc. SION FY2025 N/A -$75.3M N/A $175.9M —

Frequently Asked Questions

Is Maze Therapeutics, Inc. profitable?

No, Maze Therapeutics, Inc. (MAZE) reported a net income of -$131.1M in fiscal year 2025.

What is Maze Therapeutics, Inc.'s earnings per share (EPS)?

Maze Therapeutics, Inc. (MAZE) reported diluted earnings per share of -$3.05 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

What is Maze Therapeutics, Inc.'s EBITDA?

Maze Therapeutics, Inc. (MAZE) had EBITDA of -$140.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Maze Therapeutics, Inc. (MAZE) has a return on equity of -36.9% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Maze Therapeutics, Inc. (MAZE) recorded an outflow of $112.7M in free cash flow during fiscal year 2025. This represents a -250.7% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Maze Therapeutics, Inc. (MAZE) recorded an outflow of $111.9M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Maze Therapeutics, Inc. (MAZE) had $397.1M in total assets as of fiscal year 2025, including both current and long-term assets.

Maze Therapeutics, Inc. (MAZE) invested $794K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Maze Therapeutics, Inc. (MAZE) invested $108.4M in research and development during fiscal year 2025.

Maze Therapeutics, Inc. (MAZE) had 49M shares outstanding as of fiscal year 2025.

Maze Therapeutics, Inc. (MAZE) had a current ratio of 15.50 as of fiscal year 2025, which is generally considered healthy.

Maze Therapeutics, Inc. (MAZE) had a debt-to-equity ratio of 0.12 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Maze Therapeutics, Inc. (MAZE) had a return on assets of -33.0% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Maze Therapeutics, Inc. (MAZE) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (FY2025). The market capitalization is $1.5B as of Oct 17, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

Maze Therapeutics, Inc. (MAZE) has no price-to-sales ratio at the moment: no revenue reported. The market capitalization is $1.5B as of Oct 17, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

At the end of fiscal year 2025, Maze Therapeutics, Inc. (MAZE) held $360.0M in cash, cash equivalents and investments, and reported an operating cash outflow of $111.9M over that year. Dividing the one by the other, the reported balance equals about 39 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Maze Therapeutics, Inc. (MAZE) has a Piotroski F-Score of 2 out of 6 computable signals; 3 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Maze Therapeutics, Inc. (MAZE) reported a net loss of $131.1M while operations used $111.9M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

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