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Maze Therapeutics Financials

MAZE
Source SEC Filings (10-K/10-Q) Updated Mar 25, 2026 Currency USD FYE March

This page shows Maze Therapeutics (MAZE) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 40 / 100
Financial Profile 40/100

Based on FY2025 annual data. Scores normalized against common benchmarks. How we calculate these scores

Profitability
0

Maze Therapeutics has an operating margin of -85.3%, meaning the company retains $-85 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses.

Leverage
100

Maze Therapeutics carries a low D/E ratio of 0.12, meaning only $0.12 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 100/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
100

With a current ratio of 15.50, Maze Therapeutics holds $15.50 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 100/100.

Cash Flow
0

While Maze Therapeutics generated -$111.9M in operating cash flow, capex of $794K consumed most of it, leaving -$112.7M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.

Returns
0

Maze Therapeutics generates a -36.9% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100.

Earnings Quality Low Quality
0.85x

For every $1 of reported earnings, Maze Therapeutics generates $0.85 in operating cash flow (-$111.9M OCF vs -$131.1M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Key Financial Metrics

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Earnings & Revenue

Revenue
$167.5M

Maze Therapeutics generated $167.5M in revenue in fiscal year 2025.

EBITDA
-$140.5M

Maze Therapeutics's EBITDA was -$140.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Net Income
-$131.1M

Maze Therapeutics reported -$131.1M in net income in fiscal year 2025.

EPS (Diluted)
$-3.05

Maze Therapeutics earned $-3.05 per diluted share (EPS) in fiscal year 2025.

Cash & Balance Sheet

Free Cash Flow
-$112.7M

Maze Therapeutics generated -$112.7M in free cash flow in fiscal year 2025, representing cash available after capex.

Cash & Debt
$189.2M

Maze Therapeutics held $189.2M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
49M

Maze Therapeutics had 49M shares outstanding in fiscal year 2025.

Margins & Returns

Gross Margin
N/A
Operating Margin
-85.3%

Maze Therapeutics's operating margin was -85.3% in fiscal year 2025, reflecting core business profitability.

Net Margin
-78.3%

Maze Therapeutics's net profit margin was -78.3% in fiscal year 2025, showing the share of revenue converted to profit.

Return on Equity
-36.9%

Maze Therapeutics's ROE was -36.9% in fiscal year 2025, measuring profit generated per dollar of shareholder equity.

Capital Allocation

R&D Spending
$108.4M

Maze Therapeutics invested $108.4M in research and development in fiscal year 2025.

Share Buybacks
N/A
Capital Expenditures
$794K

Maze Therapeutics invested $794K in capex in fiscal year 2025, funding long-term assets and infrastructure.

MAZE Income Statement

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24
Revenue N/A $0 N/A N/A $2.5M-98.5% $165.0M N/A
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A
R&D Expenses $25.2M-10.4% $28.1M+1.9% $27.6M N/A $19.9M+1.6% $19.5M-10.7% $21.9M
SG&A Expenses $7.8M-7.1% $8.4M+7.0% $7.8M N/A $6.9M+16.5% $5.9M-3.9% $6.1M
Operating Income -$33.0M+9.6% -$36.5M-3.0% -$35.4M N/A -$24.2M-117.4% $139.6M+598.2% -$28.0M
Interest Expense N/A N/A N/A N/A N/A N/A N/A
Income Tax $0 $0 N/A N/A -$279K-116.2% $1.7M N/A
Net Income -$30.1M+10.7% -$33.7M-2.7% -$32.8M N/A -$24.8M-117.8% $139.1M+527.9% -$32.5M
EPS (Diluted) $-0.66+14.3% $-0.77+33.0% $-1.15 N/A $-10.25-418.3% $3.22+123.1% $-13.91

MAZE Balance Sheet

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24
Total Assets $422.1M+39.1% $303.5M-8.8% $332.8M+38.4% $240.5M N/A N/A N/A
Current Assets $391.3M+44.3% $271.1M-9.5% $299.7M+48.6% $201.7M N/A N/A N/A
Cash & Equivalents $316.8M+19.7% $264.5M-10.1% $294.4M+49.6% $196.8M+31.6% $149.6M-14.5% $175.1M+483.1% $30.0M
Inventory N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable N/A N/A N/A N/A N/A N/A N/A
Goodwill N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $42.6M+3.2% $41.3M+1.2% $40.8M-92.6% $551.7M N/A N/A N/A
Current Liabilities $22.1M+11.1% $19.9M+6.9% $18.6M-9.9% $20.7M N/A N/A N/A
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A
Total Equity $379.4M+44.7% $262.2M-10.2% $292.1M+193.9% -$311.2M-9.4% -$284.5M-8.4% -$262.4M+35.0% -$403.7M
Retained Earnings -$455.0M-7.1% -$424.9M-8.6% -$391.2M-9.1% -$358.4M N/A N/A N/A

MAZE Cash Flow Statement

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24
Operating Cash Flow -$24.6M+18.0% -$30.1M-1.8% -$29.5M N/A -$23.2M-116.0% $145.0M+718.9% -$23.4M
Capital Expenditures $68K-82.7% $393K+31.4% $299K N/A $103K-35.6% $160K-42.7% $279K
Free Cash Flow -$24.7M+18.8% -$30.4M-2.1% -$29.8M N/A -$23.3M-116.1% $144.9M+710.9% -$23.7M
Investing Cash Flow -$66.9M-16918.6% -$393K-31.4% -$299K N/A -$103K+35.6% -$160K+42.7% -$279K
Financing Cash Flow $143.8M+23389.7% $612K-99.5% $127.4M N/A -$2.1M-1496.1% $154K-99.4% $24.6M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A

MAZE Financial Ratios

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24
Gross Margin N/A N/A N/A N/A N/A N/A N/A
Operating Margin N/A N/A N/A N/A -969.2%-1053.7pp 84.6% N/A
Net Margin N/A N/A N/A N/A -990.1%-1074.4pp 84.3% N/A
Return on Equity -7.9%+4.9pp -12.8%-1.6pp -11.2% N/A N/A N/A N/A
Return on Assets -7.1%+4.0pp -11.1%-1.2pp -9.8% N/A N/A N/A N/A
Current Ratio 17.70+4.1 13.63-2.5 16.10+6.3 9.76 N/A N/A N/A
Debt-to-Equity 0.11-0.0 0.16+0.0 0.14+1.9 -1.77 N/A N/A N/A
FCF Margin N/A N/A N/A N/A -932.3%-1020.1pp 87.8% N/A

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Frequently Asked Questions

Maze Therapeutics (MAZE) reported $167.5M in total revenue for fiscal year 2025. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

No, Maze Therapeutics (MAZE) reported a net income of -$131.1M in fiscal year 2025, with a net profit margin of -78.3%.

Maze Therapeutics (MAZE) reported diluted earnings per share of $-3.05 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Maze Therapeutics (MAZE) had EBITDA of -$140.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Maze Therapeutics (MAZE) had an operating margin of -85.3% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Maze Therapeutics (MAZE) had a net profit margin of -78.3% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Maze Therapeutics (MAZE) has a return on equity of -36.9% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Maze Therapeutics (MAZE) generated -$112.7M in free cash flow during fiscal year 2025. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Maze Therapeutics (MAZE) generated -$111.9M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Maze Therapeutics (MAZE) had $397.1M in total assets as of fiscal year 2025, including both current and long-term assets.

Maze Therapeutics (MAZE) invested $794K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Maze Therapeutics (MAZE) invested $108.4M in research and development during fiscal year 2025.

Maze Therapeutics (MAZE) had 49M shares outstanding as of fiscal year 2025.

Maze Therapeutics (MAZE) had a current ratio of 15.50 as of fiscal year 2025, which is generally considered healthy.

Maze Therapeutics (MAZE) had a debt-to-equity ratio of 0.12 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Maze Therapeutics (MAZE) had a return on assets of -33.0% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Maze Therapeutics (MAZE) had $189.2M in cash against an annual operating cash burn of $111.9M. This gives an estimated cash runway of approximately 20 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Maze Therapeutics (MAZE) has an earnings quality ratio of 0.85x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Maze Therapeutics (MAZE) scores 40 out of 100 on our Financial Profile, indicating moderate overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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