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COSCIENS Biopharma Inc. (CSCI) Financials

CSCI
FY2025 annual
Revenue $7.5M -21.8% YoY
Net Income -$10.4M +32.3% YoY
Free Cash Flow -$9.2M +41.6% YoY
Operating Cash Flow -$8.5M +41.8% YoY
Source SEC Filings (10-K/10-Q) Latest period FY2025, ended Dec 31, 2025 Reported Currency USD FYE December

Newest figures come from the 10-K for FY2025, filed Mar 25, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the CSCI SEC filings page.

COSCIENS Biopharma Inc. (CSCI) reported $7.5M in revenue for fiscal year 2025, down 21.8% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 11 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI CSCI FY2025

Revenue is shrinking while recurring losses and cash outflows remain large, eroding equity and increasing reliance on balance-sheet financing.

Operating cash flow deteriorated sharply in FY2024 before improving in FY2025, but remained negative at -$8.5M. Because FY2025 net income was also a net loss of $10.4M, cash conversion broadly corroborated the accounting loss rather than showing profit converted into cash.

Revenue fell 21.8% from FY2024 to FY2025, but the net loss narrowed 32.3%; losses improved faster than sales, pointing to cost or working-capital changes rather than renewed top-line momentum. The pattern does not describe a volume-led recovery.

Equity fell from $13.2M in FY2024 to $3.8M in FY2025, even as long-term debt declined modestly. The 0.5x debt-to-equity ratio therefore reflects a thinner equity cushion more than a debt surge, while reported liquidity measured 10.3 months of the latest annual operating outflow.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 34 / 100
Financial Health Score 34/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of COSCIENS Biopharma Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
30

COSCIENS Biopharma Inc. held $7.3M in cash, cash equivalents and investments at the end of fiscal year 2025, and its operations used $8.5M of cash that year. Cash Runway ranks emerging companies on the size of that balance against the outflow behind it, and COSCIENS Biopharma Inc. scores 30/100 among other emerging companies.

Dilution
80

COSCIENS Biopharma Inc. had 3M shares outstanding at the end of fiscal year 2025, against 3M in fiscal year 2024. Dilution ranks emerging companies on how fast that count has grown over three years, where a slower rise is the better one, and COSCIENS Biopharma Inc. scores 80/100 among other emerging companies.

R&D Intensity
0

Not available for COSCIENS Biopharma Inc., and counted as zero in the overall score.

Revenue Progress
46

COSCIENS Biopharma Inc. reported revenue of $7.5M in fiscal year 2025, against $9.6M in fiscal year 2024. Revenue Progress ranks emerging companies on the three-year path of that line, and COSCIENS Biopharma Inc. scores 46/100 among other emerging companies.

Burn Trend
10

COSCIENS Biopharma Inc.'s operations used $8.5M of cash in fiscal year 2025, against $14.6M used in fiscal year 2024. Burn Trend ranks emerging companies on which way that figure has moved over three years, and COSCIENS Biopharma Inc. scores 10/100 among other emerging companies.

Balance Sheet
40

COSCIENS Biopharma Inc.'s cash, cash equivalents and investments came to $7.3M at the end of fiscal year 2025, against $17.6M of total liabilities. Balance Sheet ranks emerging companies on that comparison, and COSCIENS Biopharma Inc. scores 40/100 among other emerging companies.

Piotroski F-Score Partial
2/8

COSCIENS Biopharma Inc. passes 2 of 8 computable financial strength tests (1 of the nine could not be computed from available data). 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), both operating efficiency signals pass.

Earnings Quality No Cash Backing
N/A

COSCIENS Biopharma Inc. reported a net loss of $10.4M while operations used $8.5M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$1.8M
YoY-46.8%
QoQ+19.1%

COSCIENS Biopharma Inc. generated $1.8M in revenue in Q4 2025. This represents a decrease of 46.8% from the same quarter a year earlier. Against the prior quarter it is up 19.1%.

Net Income
-$2.2M
YoY+67.6%
QoQ-20.0%

COSCIENS Biopharma Inc. reported -$2.2M in net income in Q4 2025. This represents an increase of 67.6% from the same quarter a year earlier. Against the prior quarter it is down 20.0%.

EBITDA

Not reported for Q4 2025.

EPS (Diluted)

Not reported for Q4 2025.

Cash & Balance Sheet

Free Cash Flow
-$1.5M
YoY+54.2%
QoQ-122.9%

COSCIENS Biopharma Inc. recorded an outflow of $1.5M in free cash flow in Q4 2025, representing a cash shortfall after capex. This represents an increase of 54.2% from the same quarter a year earlier. Against the prior quarter it is down 122.9%.

Cash & Debt
$7.3M
YoY-55.4%
QoQ-14.3%
5Y CAGR-21.3%

COSCIENS Biopharma Inc. held $7.3M in cash against $1.9M in long-term debt as of Q4 2025.

Shares Outstanding
3M
YoY+1.4%

COSCIENS Biopharma Inc. had 3M shares outstanding in Q4 2025. This represents an increase of 1.4% from the same quarter a year earlier.

Dividends Per Share

Not reported for Q4 2025.

Margins & Returns

Return on Equity
-56.8%
YoY-5.7pp
QoQ-21.0pp
5Y change-46.9pp

COSCIENS Biopharma Inc.'s ROE was -56.8% in Q4 2025, measuring profit generated per dollar of shareholder equity. This is down 5.7 percentage points from the same quarter a year earlier. Against the prior quarter it is down 21.0 percentage points.

Gross Margin

Not reported for Q4 2025.

Operating Margin

Not reported for Q4 2025.

Net Margin

Not shown for Q4 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

Capital Expenditures
$46K
YoY-85.1%
QoQ+1050.0%

COSCIENS Biopharma Inc. invested $46K in capex in Q4 2025, funding long-term assets and infrastructure. This represents a decrease of 85.1% from the same quarter a year earlier. Against the prior quarter it is up 1050.0%.

R&D Spending

Not reported for Q4 2025.

Share Buybacks

Not reported for Q4 2025.

CSCI Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CSCI quarterly income statement
MetricQ4'2510-KQ3'256-KQ2'256-KQ1'25Q4'2410-KQ3'246-KQ2'246-KQ1'24
Revenue$1.8M-46.8%$1.5M-20.7%$2.7M+17.6%$1.5M-27.1%$3.3M+98.8%$1.9M-4.1%$2.3M+67.9%$2.1M-3.3%
Interest Expense$17K+100.8%$504K+18.3%-$347K-118.7%-$38K-3900.0%-$2.2M-220000.0%$426K+246.3%$1.9M+9684.2%$1K+102.1%
Income TaxN/AN/A$1K+100.2%N/A$1.1M-$112K+47.2%-$474K-101.7%-$412K
Net Income-$2.2M+67.6%-$1.8M+68.4%-$2.7M-89.9%-$3.7M-160.9%-$6.7M-379.8%-$5.8M-641.6%-$1.4M-65.3%-$1.4M+67.1%
Diluted Shares (Avg)N/A3M+2.3%3M+43.0%3M+70.2%N/A3M+68.1%2M+20.2%2M+52.2%

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, R&D Expenses, SG&A Expenses, Operating Income, EBITDA, EPS (Basic), EPS (Diluted).

CSCI Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CSCI quarterly balance sheet
MetricQ4'2510-KQ3'256-KQ2'256-KQ1'25Q4'2410-KQ3'246-KQ2'246-KQ1'24
Total Assets$21.4M-38.9%$23.9M-45.5%$27.6M-44.9%$31.1M-2.0%$35.1M+47.7%$43.8M+3.0%$50.0M+7.7%$31.8M-38.0%
Current Assets$11.5M-52.0%$13.8M-51.0%$16.5M-50.3%$20.4M-34.8%$24.0M+112.8%$28.2M-32.7%$33.2M-27.6%$31.2M-38.5%
Cash & Equivalents$7.3M-55.4%$8.5M-57.4%$9.3M-66.4%$13.8M+292.4%$16.4M+145.5%$20.0M+139.1%$27.8M+225.7%$3.5M-62.3%
Inventory$1.3M-51.4%$1.8M-46.8%$1.8M-40.4%$2.5M+3735.9%$2.7M-32.9%$3.3M$3.1M$64K
Accounts Receivable$1.3M-46.5%$1.6M-15.2%$2.8M+124.8%$1.9M+878.4%$2.4M+712.8%$1.9M+246.5%$1.2M+569.2%$190K-65.9%
Total Liabilities$17.6M-19.7%$18.8M-20.9%$20.5M-14.1%$21.0M+11.6%$21.9M+708.5%$23.8M+46.6%$23.8M+36.9%$18.8M-6.2%
Current Liabilities$3.6M-50.0%$4.0M-51.2%$5.5M-44.1%$7.1M+34.4%$7.2M+450.9%$8.2M+93.2%$9.9M+142.8%$5.3M-18.4%
Non-Current Liabilities$14.0M-4.8%$14.8M-5.1%$14.9M+7.2%$13.9M+2.7%$14.7M+949.8%$15.6M+30.1%$13.9M+4.4%$13.6M-0.5%
Long-Term Debt$1.9M-5.1%$2.0M+61.8%$2.0M+60.1%$2.0M+2366.3%$2.0M+45.7%$1.2M+1630.0%$1.3M+1405.9%$80K+5.3%
Total Equity$3.8M-70.8%$5.1M-74.6%$7.1M-72.9%$10.1M-47.1%$13.2M-37.4%$20.0M-9.3%$26.2M+12.2%$19.2M-38.5%
Retained Earnings-$20.5M-69.3%-$19.0M-269.3%-$17.2M-1223.7%-$14.7M+96.1%-$12.1M-378.0%-$5.2M+98.6%$1.5M+100.4%-$375.3M-5.3%

Not reported in any period shown, so not listed: Short-Term Investments, Long-Term Investments, Goodwill.

CSCI Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CSCI quarterly cash flow statement
MetricQ4'2510-KQ3'256-KQ2'256-KQ1'25Q4'2410-KQ3'246-KQ2'246-KQ1'24
Operating Cash Flow-$1.5M+51.0%-$676K+91.3%-$4.4M-220.2%-$1.9M+21.0%-$3.0M-176.4%-$7.8M-5502.1%-$1.4M-70.8%-$2.4M+41.4%
Depreciation & Amortization$289K-26.3%$287K-40.1%$287K-23.9%$325K-9.5%$392K-42.2%$479K+32.0%$377K+4.1%$359K+797.5%
Capital Expenditures$46K-85.1%-$4K-96.9%$49K-68.8%$615K+9.0%$309K-47.4%$131K+162.0%$157K+190.7%$564K+28100.0%
Free Cash Flow-$1.5M+54.2%-$680K+91.4%-$4.5M-190.8%-$2.5M+15.3%-$3.3M-97.8%-$7.9M-8514.9%-$1.5M-78.3%-$2.9M+27.5%
Investing Cash Flow$201K+163.6%$4K-95.2%-$48K-100.2%-$615K-9.0%-$316K+46.9%$83K+266.0%$25.9M+48025.9%-$564K-28100.0%
Financing Cash Flow-$15K+92.6%-$85K+54.8%-$107K+15.1%-$200K-112.8%-$202K-22.4%-$188K-218.6%-$126K-80.0%-$94K-147.4%

Not reported in any period shown, so not listed: Stock-Based Compensation, Dividends Paid, Share Buybacks.

CSCI Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

CSCI quarterly financial ratios
MetricQ4'2510-KQ3'256-KQ2'256-KQ1'25Q4'2410-KQ3'246-KQ2'246-KQ1'24
Net Margin-123.6%-122.7%-98.3%-37.4pp-243.7%-202.6%-307.6%-60.9%+0.9pp-68.1%
Return on Equity-56.8%-5.7pp-35.8%-7.1pp-38.1%-32.6pp-36.0%-28.7pp-51.1%-62.6pp-28.7%-25.2pp-5.4%-1.7pp-7.3%+6.3pp
Return on Assets-10.2%+9.0pp-7.6%+5.5pp-9.8%-7.0pp-11.7%-7.3pp-19.2%-29.3pp-13.2%-11.3pp-2.8%-1.0pp-4.4%+3.9pp
Current Ratio3.18-0.1x3.470.0x2.98-0.4x2.88-3.1x3.32-5.3x3.46-6.5x3.35-7.9x5.94-1.9x
Debt-to-Equity0.50+0.3x0.39+0.3x0.29+0.2x0.19+0.2x0.15+0.1x0.06+0.1x0.050.0x0.000.0x
Asset Turnover0.080.0x0.060.0x0.10+0.1x0.050.0x0.090.0x0.040.0x0.050.0x0.060.0x
FCF Margin-85.8%+13.7pp-45.9%-163.5%-166.3%-99.6%-422.8%-66.1%-3.9pp-143.1%

Not reported in any period shown, so not listed: Gross Margin, Operating Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Net Margin, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
COSCIENS Biopharma Inc. CSCI FY2025 $7.5M -$10.4M N/A $8.6M 34/100
AEON Biopharma, Inc. AEON FY2025 N/A N/A N/A $11.4M —
Creative Medical Technology Holdings, Inc. CELZ FY2025 $6K -$6.0M N/A $5.9M —
Cyclerion Therapeutics, Inc. CYCN FY2025 $2.1M -$3.5M N/A $19.9M 59/100
Impact BioMedical, Inc. IBO FY2025 $32K -$11.8M N/A $29.1M —

Frequently Asked Questions

What is COSCIENS Biopharma Inc.'s annual revenue?

COSCIENS Biopharma Inc. (CSCI) reported $7.5M in total revenue for fiscal year 2025. This represents a -21.8% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is COSCIENS Biopharma Inc.'s revenue growing?

COSCIENS Biopharma Inc. (CSCI) revenue declined by 21.8% year-over-year, from $9.6M to $7.5M in fiscal year 2025.

Is COSCIENS Biopharma Inc. profitable?

No, COSCIENS Biopharma Inc. (CSCI) reported a net income of -$10.4M in fiscal year 2025.

As of fiscal year 2025, COSCIENS Biopharma Inc. (CSCI) had $7.3M in cash and equivalents against $1.9M in long-term debt.

COSCIENS Biopharma Inc. (CSCI) has a return on equity of -269.6% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

COSCIENS Biopharma Inc. (CSCI) recorded an outflow of $9.2M in free cash flow during fiscal year 2025. This represents a 41.6% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

COSCIENS Biopharma Inc. (CSCI) recorded an outflow of $8.5M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

COSCIENS Biopharma Inc. (CSCI) had $21.4M in total assets as of fiscal year 2025, including both current and long-term assets.

COSCIENS Biopharma Inc. (CSCI) invested $706K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

COSCIENS Biopharma Inc. (CSCI) had 3M shares outstanding as of fiscal year 2025.

COSCIENS Biopharma Inc. (CSCI) had a current ratio of 3.18 as of fiscal year 2025, which is generally considered healthy.

COSCIENS Biopharma Inc. (CSCI) had a debt-to-equity ratio of 0.50 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

COSCIENS Biopharma Inc. (CSCI) had a return on assets of -48.3% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

At the end of fiscal year 2025, COSCIENS Biopharma Inc. (CSCI) held $7.3M in cash, cash equivalents and investments, and reported an operating cash outflow of $8.5M over that year. Dividing the one by the other, the reported balance equals about 10 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

COSCIENS Biopharma Inc. (CSCI) has a Piotroski F-Score of 2 out of 8 computable signals; 1 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

COSCIENS Biopharma Inc. (CSCI) reported a net loss of $10.4M while operations used $8.5M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

COSCIENS Biopharma Inc. (CSCI) scores 34 out of 100 on our Financial Health Score, indicating weak standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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