STOCK TITAN

Definium Therapeutics, Inc. (DFTX) Financials

DFTX
FY2025 annual
Revenue Not reported for FY2025
Net Income -$183.8M -69.1% YoY
EPS (Diluted) -$2.06 -33.8% YoY
Operating Cash Flow -$131.6M -66.3% YoY
Market Cap $4.9B as of Sep 25, 2026
Price / Sales n/m no revenue reported
Price / Earnings n/m net loss, so no earnings multiple, FY2025
Price / Book 5.3x on $918.7M equity, Q2 FY2026

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Sep 25, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q2 FY2026, filed Aug 6, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the DFTX SEC filings page.

This page shows Definium Therapeutics, Inc. (DFTX) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI DFTX FY2025

Definium operates as a financing-dependent development business, with escalating research spending and no reported commercial revenue.

From FY2024 to FY2025, research and development spending increased from $65.3M to $117.7M, while operating cash flow also worsened, linking heavier development investment to greater cash consumption. Financing inflows offset that pressure, but the simultaneous investing outflow shows capital is being raised and deployed rather than generated internally.

FY2025’s operating loss reached -$166.3M, with R&D at $117.7M; the cost structure is therefore dominated by product development rather than commercial operations. The absence of reported revenue across the periods means profitability metrics cannot yet show operating scale or margin leverage.

The FY2025 balance sheet had a current ratio of 6.3x and debt-to-equity of 0.1x, indicating limited balance-sheet leverage despite continued losses. The reported 37.5 months of liquidity is a comparison of period-end cash and investments with the latest annual operating outflow, while financing inflows of $267.3M supplied the year’s main funding source.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Financial health score not available

Definium Therapeutics, Inc. does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.

Piotroski F-Score Partial
1/7

Definium Therapeutics, Inc. passes 1 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution).

Earnings Quality No Cash Backing
N/A

Definium Therapeutics, Inc. reported a net loss of $183.8M while operations used $131.6M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Definium Therapeutics, Inc. reported an operating loss of $166.3M against $5.5M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

Export CSV

Earnings & Revenue

Net Income
-$159.0M
YoY-271.9%
QoQ-106.2%

Definium Therapeutics, Inc. reported -$159.0M in net income in Q2 2026. This represents a decrease of 271.9% from the same quarter a year earlier. Against the prior quarter it is down 106.2%.

EPS (Diluted)
-$1.44
YoY-188.0%
QoQ-102.8%

Definium Therapeutics, Inc. earned -$1.44 per diluted share (EPS) in Q2 2026. This represents a decrease of 188.0% from the same quarter a year earlier. Against the prior quarter it is down 102.8%.

Revenue

Not reported for Q2 2026.

EBITDA

Not reported for Q2 2026.

Cash & Balance Sheet

Cash & Debt
$655.3M
YoY+1862.3%
QoQ+149.6%

Definium Therapeutics, Inc. held $655.3M in cash against $36.5M in long-term debt as of Q2 2026.

Shares Outstanding
134M
YoY+76.6%
QoQ+23.2%

Definium Therapeutics, Inc. had 134M shares outstanding in Q2 2026. This represents an increase of 76.6% from the same quarter a year earlier. Against the prior quarter it is up 23.2%.

Free Cash Flow

Not reported for Q2 2026.

Dividends Per Share

Not reported for Q2 2026.

Margins & Returns

Return on Equity
-17.3%
YoY+5.8pp
QoQ+10.3pp

Definium Therapeutics, Inc.'s ROE was -17.3% in Q2 2026, measuring profit generated per dollar of shareholder equity. This is up 5.8 percentage points from the same quarter a year earlier. Against the prior quarter it is up 10.3 percentage points.

Gross Margin

Not reported for Q2 2026.

Operating Margin

Not reported for Q2 2026.

Net Margin

Not reported for Q2 2026.

Capital Allocation

R&D Spending
$48.7M
YoY+63.3%
QoQ+17.3%

Definium Therapeutics, Inc. invested $48.7M in research and development in Q2 2026. This represents an increase of 63.3% from the same quarter a year earlier. Against the prior quarter it is up 17.3%.

Share Buybacks

Not reported for Q2 2026.

Capital Expenditures

Not reported for Q2 2026.

DFTX Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

DFTX quarterly income statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
R&D Expenses$48.7M+63.3%$41.5M+77.6%N/A$31.0M+80.2%$29.8M+103.5%$23.4M+99.5%N/A$17.2M+30.2%
SG&A Expenses$26.4M+138.1%$17.7M+101.5%N/A$14.7M+93.2%$11.1M+13.1%$8.8M-16.2%N/A$7.6M-9.6%
Operating Income-$75.1M-83.5%-$59.2M-84.1%N/A-$45.7M-84.2%-$40.9M-67.2%-$32.2M-44.8%N/A-$24.8M-14.7%
Interest Expense$1.2M-47.3%$1.2M+106.8%N/A$1.3M+75.2%$2.3M+401.7%$602K+38.7%N/A$727K+121.6%
Net Income-$159.0M-271.9%-$77.1M-230.2%N/A-$67.3M-391.6%-$42.7M-630.2%-$23.3M+57.1%N/A-$13.7M+23.7%
EPS (Basic)-$1.44-188.0%-$0.71-163.0%-$0.50-19.0%-$0.78-333.3%-$0.50-525.0%-$0.27+76.3%-$0.42+28.8%-$0.18+60.0%
EPS (Diluted)-$1.44-188.0%-$0.71-$0.50-19.0%-$0.78-$0.50-$0.35+69.3%-$0.42-$0.27
Diluted Shares (Avg)111M+29.7%109MN/A86M85M87M+82.0%N/A80M

Not reported in any period shown, so not listed: Revenue, Cost of Revenue, Gross Profit, EBITDA, Income Tax.

DFTX Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

DFTX quarterly balance sheet
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Total Assets$1.1B+319.8%$401.3M+45.8%$440.1M+45.7%$236.9M-25.9%$265.1M-1.1%$275.3M-0.1%$302.2M+142.6%$319.8M+125.9%
Current Assets$1.1B+477.4%$380.6M+71.7%$419.3M+48.9%$215.8M-27.9%$189.1M-23.6%$221.7M-13.2%$281.6M+171.1%$299.4M+149.3%
Cash & Equivalents$655.3M+1862.3%$262.5M+216.8%$257.8M-5.8%$20.0M-93.2%$33.4M-86.3%$82.9M-67.2%$273.7M+174.6%$295.3M+150.9%
Short-Term Investments$428.6M+186.5%$110.9M-14.4%$153.8M$189.1M$149.6M$129.6M$0$0
Long-Term Investments$0-100.0%$0-100.0%$0$0$54.9M$33.1M$0$0
Goodwill$19.9M0.0%$19.9M0.0%$19.9M0.0%$19.9M0.0%$19.9M0.0%$19.9M0.0%$19.9M0.0%$19.9M0.0%
Total Liabilities$194.2M+143.7%$122.4M+133.2%$107.8M+77.5%$106.3M+84.7%$79.7M+20.6%$52.5M-33.9%$60.7M+30.8%$57.6M+26.3%
Current Liabilities$157.2M+314.2%$81.1M+166.1%$66.7M+71.7%$65.4M+96.7%$38.0M-9.3%$30.5M-53.3%$38.8M+20.5%$33.3M+6.8%
Non-Current Liabilities$37.0M-11.3%$41.3M+87.6%$41.1M+88.0%$40.9M+68.3%$41.7M+72.1%$22.0M+55.1%$21.9M+54.3%$24.3M+68.6%
Long-Term Debt$36.5M-11.5%$40.8M+85.0%$40.6M+85.7%$40.4M+66.1%$41.2M+69.9%$22.0M+55.3%$21.9M+54.7%$24.3M+72.8%
Total Equity$918.7M+395.5%$278.8M+25.2%$332.3M+37.6%$130.6M-50.2%$185.4M-8.2%$222.8M+13.6%$241.4M+209.0%$262.2M+173.2%
Retained Earnings-$818.8M-76.1%-$659.8M-56.3%-$582.7M-46.1%-$532.2M-46.2%-$465.0M-32.7%-$422.2M-22.5%-$398.9M-37.4%-$364.1M-36.7%

Not reported in any period shown, so not listed: Inventory, Accounts Receivable.

DFTX Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

DFTX quarterly cash flow statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Cash Flow-$52.8M-78.3%-$42.6M-44.9%-$43.0M-69.5%-$29.6M-72.0%-$29.6M-48.1%-$29.4M-77.2%-$25.4M-23.3%-$17.2M-3.4%
Stock-Based Compensation$9.6M+83.5%$7.1M+108.2%N/A$5.8M+51.4%$5.3M-3.3%$3.4M-7.1%N/A$3.8M-9.1%
Investing Cash Flow-$316.7M-701.1%$42.0M+125.9%$35.0M$15.4M-$39.5M-$162.5M$0$0
Financing Cash Flow$762.3M+3779.2%$5.3M+429.8%$245.9M+6358.3%$749K-98.9%$19.6M+82.1%$1.0M-99.4%$3.8M+46.8%$69.4M+298.6%

Not reported in any period shown, so not listed: Depreciation & Amortization, Capital Expenditures, Free Cash Flow, Dividends Paid, Share Buybacks.

DFTX Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

DFTX quarterly financial ratios
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Return on Equity-17.3%+5.8pp-27.7%-17.2ppN/A-51.5%-46.3pp-23.1%-20.2pp-10.5%+17.3ppN/A-5.2%+13.5pp
Return on Assets-14.3%+1.8pp-19.2%-10.7ppN/A-28.4%-24.1pp-16.1%-13.9pp-8.5%+11.3ppN/A-4.3%+8.4pp
Current Ratio6.95+2.0x4.69-2.6x6.29-1.0x3.30-5.7x4.98-0.9x7.27+3.4x7.25+4.0x9.00+5.1x
Debt-to-Equity0.04-0.2x0.150.0x0.120.0x0.31+0.2x0.22+0.1x0.100.0x0.09-0.1x0.09-0.1x

Not reported in any period shown, so not listed: Gross Margin, Operating Margin, Net Margin, Asset Turnover, FCF Margin.

Frequently Asked Questions

Is Definium Therapeutics, Inc. profitable?

No, Definium Therapeutics, Inc. (DFTX) reported a net income of -$183.8M in fiscal year 2025.

What is Definium Therapeutics, Inc.'s earnings per share (EPS)?

Definium Therapeutics, Inc. (DFTX) reported diluted earnings per share of -$2.06 for fiscal year 2025. This represents a -33.8% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

How much debt does Definium Therapeutics, Inc. have?

As of fiscal year 2025, Definium Therapeutics, Inc. (DFTX) had $257.8M in cash and equivalents against $40.6M in long-term debt.

Definium Therapeutics, Inc. (DFTX) has a return on equity of -55.3% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Definium Therapeutics, Inc. (DFTX) recorded an outflow of $131.6M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Definium Therapeutics, Inc. (DFTX) had $440.1M in total assets as of fiscal year 2025, including both current and long-term assets.

Definium Therapeutics, Inc. (DFTX) invested $117.7M in research and development during fiscal year 2025.

Definium Therapeutics, Inc. (DFTX) had 100M shares outstanding as of fiscal year 2025.

Definium Therapeutics, Inc. (DFTX) had a current ratio of 6.29 as of fiscal year 2025, which is generally considered healthy.

Definium Therapeutics, Inc. (DFTX) had a debt-to-equity ratio of 0.12 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Definium Therapeutics, Inc. (DFTX) had a return on assets of -41.8% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Definium Therapeutics, Inc. (DFTX) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (FY2025). The market capitalization is $4.9B as of Sep 25, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

Definium Therapeutics, Inc. (DFTX) has no price-to-sales ratio at the moment: no revenue reported. The market capitalization is $4.9B as of Sep 25, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

At the end of fiscal year 2025, Definium Therapeutics, Inc. (DFTX) held $411.6M in cash, cash equivalents and investments, and reported an operating cash outflow of $131.6M over that year. Dividing the one by the other, the reported balance equals about 38 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Definium Therapeutics, Inc. (DFTX) has a Piotroski F-Score of 1 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Definium Therapeutics, Inc. (DFTX) reported a net loss of $183.8M while operations used $131.6M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Definium Therapeutics, Inc. (DFTX) reported an operating loss of $166.3M against $5.5M in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Back to top