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Amicus Therapeut Financials

FOLD
Source SEC Filings (10-K/10-Q) Updated Dec 31, 2025 Currency USD FYE December

This page shows Amicus Therapeut (FOLD) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 24 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 44 / 100
Financial Profile 44/100

Based on FY2025 annual data. Scores normalized against common benchmarks. How we calculate these scores

Profitability
34

Amicus Therapeut has an operating margin of 5.2%, meaning the company retains $5 of operating profit per $100 of revenue. This results in a moderate score of 34/100, indicating healthy but not exceptional operating efficiency. This is up from 4.7% the prior year.

Growth
67

Amicus Therapeut's revenue surged 20.0% year-over-year to $634.2M, reflecting rapid business expansion. This strong growth earns a score of 67/100.

Leverage
73

Amicus Therapeut carries a low D/E ratio of 1.43, meaning only $1.43 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 73/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
54

Amicus Therapeut's current ratio of 2.84 indicates adequate short-term liquidity, earning a score of 54/100. The company can meet its near-term obligations, though with limited headroom.

Cash Flow
37

Amicus Therapeut has a free cash flow margin of 4.7%, earning a moderate score of 37/100. The company generates positive cash flow after capital investments, but with room for improvement.

Returns
0

Amicus Therapeut generates a -9.9% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100. This is up from -28.9% the prior year.

Altman Z-Score Distress
1.28

Amicus Therapeut scores 1.28, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($4.5B) relative to total liabilities ($675.6M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Piotroski F-Score Neutral
4/9

Amicus Therapeut passes 4 of 9 financial strength tests. 3 of 4 profitability signals pass, 1 of 3 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality Mixed
-1.22x

For every $1 of reported earnings, Amicus Therapeut generates $-1.22 in operating cash flow ($33.1M OCF vs -$27.1M net income). This mixed ratio suggests some earnings may rely on non-cash accounting items.

Interest Coverage At Risk
0.7x

Amicus Therapeut earns $0.7 in operating income for every $1 of interest expense ($32.8M vs $46.2M). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$634.2M
YoY+20.0%
5Y CAGR+19.4%

Amicus Therapeut generated $634.2M in revenue in fiscal year 2025. This represents an increase of 20.0% from the prior year.

EBITDA
$40.2M
YoY+20.4%

Amicus Therapeut's EBITDA was $40.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 20.4% from the prior year.

Net Income
-$27.1M
YoY+51.7%

Amicus Therapeut reported -$27.1M in net income in fiscal year 2025. This represents an increase of 51.7% from the prior year.

EPS (Diluted)
$-0.09
YoY+50.0%

Amicus Therapeut earned $-0.09 per diluted share (EPS) in fiscal year 2025. This represents an increase of 50.0% from the prior year.

Cash & Balance Sheet

Free Cash Flow
$29.8M
YoY+179.7%

Amicus Therapeut generated $29.8M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 179.7% from the prior year.

Cash & Debt
$214.0M
YoY+0.1%
5Y CAGR+5.6%
10Y CAGR+11.9%

Amicus Therapeut held $214.0M in cash against $392.7M in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
314M
YoY+4.6%
5Y CAGR+3.7%
10Y CAGR+9.6%

Amicus Therapeut had 314M shares outstanding in fiscal year 2025. This represents an increase of 4.6% from the prior year.

Margins & Returns

Gross Margin
88.5%
YoY-1.5pp
5Y CAGR+0.4pp

Amicus Therapeut's gross margin was 88.5% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. This is down 1.5 percentage points from the prior year.

Operating Margin
5.2%
YoY+0.5pp
5Y CAGR+99.8pp

Amicus Therapeut's operating margin was 5.2% in fiscal year 2025, reflecting core business profitability. This is up 0.5 percentage points from the prior year.

Net Margin
-4.3%
YoY+6.3pp
5Y CAGR+101.8pp

Amicus Therapeut's net profit margin was -4.3% in fiscal year 2025, showing the share of revenue converted to profit. This is up 6.3 percentage points from the prior year.

Return on Equity
-9.9%
YoY+19.0pp
5Y CAGR+86.8pp
10Y CAGR+28.1pp

Amicus Therapeut's ROE was -9.9% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 19.0 percentage points from the prior year.

Capital Allocation

R&D Spending
$135.8M
YoY+24.2%
5Y CAGR-15.1%
10Y CAGR+5.8%

Amicus Therapeut invested $135.8M in research and development in fiscal year 2025. This represents an increase of 24.2% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$3.3M
YoY-7.2%
5Y CAGR+0.4%
10Y CAGR-3.7%

Amicus Therapeut invested $3.3M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 7.2% from the prior year.

FOLD Income Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Revenue $185.2M+9.6% $169.1M+9.3% $154.7M+23.5% $125.2M-16.3% $149.7M+5.8% $141.5M+11.7% $126.7M+14.7% $110.4M
Cost of Revenue $26.5M+36.4% $19.5M+27.9% $15.2M+30.1% $11.7M-21.2% $14.8M+11.7% $13.3M+17.9% $11.3M-17.0% $13.6M
Gross Profit $158.7M+6.1% $149.6M+7.3% $139.5M+22.8% $113.6M-15.8% $134.9M+5.2% $128.2M+11.1% $115.4M+19.2% $96.8M
R&D Expenses $23.7M+1.4% $23.4M-61.5% $60.8M+118.6% $27.8M-7.8% $30.2M+15.4% $26.2M+6.0% $24.7M-12.9% $28.3M
SG&A Expenses $117.1M+30.0% $90.0M+6.5% $84.5M-7.9% $91.8M+6.0% $86.7M+15.4% $75.1M+2.1% $73.6M-16.4% $88.0M
Operating Income $15.9M-53.5% $34.3M+461.7% -$9.5M-19.1% -$8.0M-149.8% $16.0M-26.3% $21.7M+44.7% $15.0M+154.0% -$27.7M
Interest Expense $11.4M-2.4% $11.7M+1.3% $11.6M+1.0% $11.5M-4.2% $12.0M-5.8% $12.7M+1.4% $12.5M+0.6% $12.4M
Income Tax $1.5M-91.4% $17.0M+223.9% $5.2M+43.9% $3.6M+153.5% -$6.8M-150.4% $13.5M-14.5% $15.8M+226.8% $4.8M
Net Income $1.7M-90.2% $17.3M+170.9% -$24.4M-12.6% -$21.7M-247.1% $14.7M+319.0% -$6.7M+57.1% -$15.7M+67.6% -$48.4M
EPS (Diluted) N/A $0.06+175.0% $-0.08-14.3% $-0.07 N/A $-0.02+60.0% $-0.05+68.8% $-0.16

FOLD Balance Sheet

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Total Assets $949.9M+9.3% $868.8M+6.6% $815.3M+3.2% $789.8M+0.6% $785.0M-0.2% $786.6M+4.9% $749.5M+3.8% $721.8M
Current Assets $676.2M+13.8% $594.1M+10.4% $538.0M+5.3% $510.8M+1.2% $504.7M+1.3% $498.5M+8.0% $461.7M+7.1% $431.2M
Cash & Equivalents $214.0M+12.3% $190.6M+20.1% $158.7M-12.6% $181.7M-15.0% $213.8M-8.5% $233.6M+11.6% $209.3M-0.2% $209.8M
Inventory $228.8M+28.6% $177.9M+14.9% $154.9M+17.0% $132.4M+11.5% $118.8M+3.0% $115.3M+41.8% $81.3M+33.8% $60.8M
Accounts Receivable $115.3M+1.3% $113.8M+7.5% $105.8M+19.8% $88.3M-12.6% $101.1M+3.1% $98.1M+15.1% $85.2M+11.4% $76.4M
Goodwill $197.8M0.0% $197.8M0.0% $197.8M0.0% $197.8M0.0% $197.8M0.0% $197.8M0.0% $197.8M0.0% $197.8M
Total Liabilities $675.6M+5.8% $638.4M+4.5% $611.0M+2.5% $596.3M+0.9% $591.0M-2.8% $607.7M-1.5% $617.0M+4.4% $591.1M
Current Liabilities $237.8M+19.6% $198.9M+18.7% $167.6M+9.7% $152.9M+2.8% $148.7M-6.0% $158.1M-5.9% $168.1M+18.3% $142.1M
Long-Term Debt $392.7M+0.2% $392.0M+0.2% $391.3M+0.2% $390.7M+0.2% $390.1M+0.2% $389.5M+0.1% $388.9M+0.1% $388.4M
Total Equity $274.2M+19.0% $230.4M+12.8% $204.3M+5.6% $193.6M-0.3% $194.0M+8.5% $178.8M+34.9% $132.5M+1.4% $130.7M
Retained Earnings -$2.8B+0.1% -$2.8B+0.6% -$2.8B-0.9% -$2.8B-0.8% -$2.7B+0.5% -$2.8B-0.2% -$2.7B-0.6% -$2.7B

FOLD Cash Flow Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Operating Cash Flow $16.3M-54.4% $35.7M+234.4% -$26.5M-441.9% $7.8M+298.1% -$3.9M+83.0% -$23.0M-201.2% $22.7M+176.4% -$29.7M
Capital Expenditures $299K-21.7% $382K-84.1% $2.4M+1033.5% $212K-26.4% $288K-19.1% $356K-67.6% $1.1M-39.4% $1.8M
Free Cash Flow $16.0M-54.8% $35.3M+221.9% -$28.9M-483.4% $7.5M+279.5% -$4.2M+82.0% -$23.3M-208.0% $21.6M+168.5% -$31.5M
Investing Cash Flow -$6.5M-399.9% -$1.3M+77.5% -$5.8M+82.4% -$32.9M-61.1% -$20.4M-159.5% $34.3M+255.9% -$22.0M-391.6% $7.5M
Financing Cash Flow $14.0M+1163.6% -$1.3M-229.8% -$400K+96.6% -$11.7M-1166.5% $1.1M-94.0% $18.2M+2222.5% -$857K+93.6% -$13.3M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

FOLD Financial Ratios

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Gross Margin 85.7%-2.8pp 88.5%-1.7pp 90.2%-0.5pp 90.7%+0.6pp 90.1%-0.5pp 90.6%-0.5pp 91.1%+3.4pp 87.7%
Operating Margin 8.6%-11.7pp 20.3%+26.4pp -6.1%+0.2pp -6.3%-17.0pp 10.7%-4.6pp 15.3%+3.5pp 11.8%+36.9pp -25.1%
Net Margin 0.9%-9.3pp 10.2%+26.0pp -15.8%+1.5pp -17.3%-27.2pp 9.8%+14.6pp -4.8%+7.6pp -12.4%+31.5pp -43.9%
Return on Equity 0.6%-6.9pp 7.5%+19.5pp -11.9%-0.7pp -11.2%-18.8pp 7.6%+11.4pp -3.8%+8.1pp -11.8%+25.2pp -37.0%
Return on Assets 0.2%-1.8pp 2.0%+5.0pp -3.0%-0.2pp -2.8%-4.6pp 1.9%+2.7pp -0.9%+1.2pp -2.1%+4.6pp -6.7%
Current Ratio 2.84-0.1 2.99-0.2 3.21-0.1 3.34-0.1 3.39+0.2 3.15+0.4 2.75-0.3 3.03
Debt-to-Equity 1.43-0.3 1.70-0.2 1.92-0.1 2.020.0 2.01-0.2 2.18-0.8 2.93-0.0 2.97
FCF Margin 8.6%-12.3pp 20.9%+39.6pp -18.7%-24.7pp 6.0%+8.8pp -2.8%+13.7pp -16.5%-33.5pp 17.1%+45.6pp -28.5%

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Frequently Asked Questions

Amicus Therapeut (FOLD) reported $634.2M in total revenue for fiscal year 2025. This represents a 20.0% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Amicus Therapeut (FOLD) revenue grew by 20% year-over-year, from $528.3M to $634.2M in fiscal year 2025.

No, Amicus Therapeut (FOLD) reported a net income of -$27.1M in fiscal year 2025, with a net profit margin of -4.3%.

Amicus Therapeut (FOLD) reported diluted earnings per share of $-0.09 for fiscal year 2025. This represents a 50.0% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Amicus Therapeut (FOLD) had EBITDA of $40.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Amicus Therapeut (FOLD) had $214.0M in cash and equivalents against $392.7M in long-term debt.

Amicus Therapeut (FOLD) had a gross margin of 88.5% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.

Amicus Therapeut (FOLD) had an operating margin of 5.2% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Amicus Therapeut (FOLD) had a net profit margin of -4.3% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Amicus Therapeut (FOLD) has a return on equity of -9.9% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Amicus Therapeut (FOLD) generated $29.8M in free cash flow during fiscal year 2025. This represents a 179.7% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Amicus Therapeut (FOLD) generated $33.1M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Amicus Therapeut (FOLD) had $949.9M in total assets as of fiscal year 2025, including both current and long-term assets.

Amicus Therapeut (FOLD) invested $3.3M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Amicus Therapeut (FOLD) invested $135.8M in research and development during fiscal year 2025.

Amicus Therapeut (FOLD) had 314M shares outstanding as of fiscal year 2025.

Amicus Therapeut (FOLD) had a current ratio of 2.84 as of fiscal year 2025, which is generally considered healthy.

Amicus Therapeut (FOLD) had a debt-to-equity ratio of 1.43 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Amicus Therapeut (FOLD) had a return on assets of -2.9% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Amicus Therapeut (FOLD) has an Altman Z-Score of 1.28, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios—working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets—to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Amicus Therapeut (FOLD) has a Piotroski F-Score of 4 out of 9, indicating neutral financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Amicus Therapeut (FOLD) has an earnings quality ratio of -1.22x, considered mixed quality. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Amicus Therapeut (FOLD) has an interest coverage ratio of 0.7x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Amicus Therapeut (FOLD) scores 44 out of 100 on our Financial Profile, indicating moderate overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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