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Iovance Biotherp Financials

IOVA
Trailing 12 months to June 30, 2026
Revenue $325.0M +34.5% YoY
Net Income -$289.5M +25.7% YoY
EPS (Diluted) -$1.09 FY2025 annual
Free Cash Flow -$296.4M +8.4% YoY
Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Iovance Biotherp (IOVA) reported $325.0M in revenue over the twelve months to Jun 30, 2026, up 34.5% from the prior twelve months. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 15 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI IOVA FY2025

Revenue scaling has not yet absorbed development spending, leaving operations dependent on recurring external financing.

Revenue reached $263.5M in FY2025 from $164.1M in FY2024, yet gross margin compressed, so growth has not translated into a stronger cost structure. Operating loss remained roughly unchanged despite that sales increase, revealing that operating and development costs still dominate the income statement.

Development spending remains the central cash mechanic: R&D exceeded FY2025 revenue, while operating cash flow of -$302.4M indicates sales are not yet funding the business internally. Capital spending pushed free cash flow to -$336.2M, making cash conversion weaker than operating cash flow alone suggests.

Financing supplied $300.8M in FY2025 against operating cash flow of -$302.4M, meaning external capital effectively financed the year's operating outflow. The share count rose from 305.3M to 412.0M between FY2024 and FY2025, a balance-sheet consequence consistent with equity-based funding.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 60 / 100
Financial Health Score 60/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Iovance Biotherp's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
32
Dilution
30
R&D Intensity
76
Revenue Progress
100
Burn Trend
51
Balance Sheet
69
Altman Z-Score Safe
5.12

Iovance Biotherp scores 5.12, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($3.6B) relative to total liabilities ($214.6M). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
2/8

Iovance Biotherp passes 2 of 8 computable financial strength tests (1 of the nine could not be computed from available data). 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), 1 of 2 efficiency signals pass.

Earnings Quality No Cash Backing
N/A

Iovance Biotherp reported a net loss of $391.0M while operations used $302.4M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$263.5M
YoY+60.6%

Iovance Biotherp generated $263.5M in revenue in fiscal year 2025. This represents an increase of 60.6% from the prior year.

EBITDA
-$390.5M
YoY-1.7%

Iovance Biotherp's EBITDA was -$390.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 1.7% from the prior year.

Net Income
-$391.0M
YoY-5.1%

Iovance Biotherp reported -$391.0M in net income in fiscal year 2025. This represents a decrease of 5.1% from the prior year.

EPS (Diluted)
-$1.09
YoY+14.8%

Iovance Biotherp earned -$1.09 per diluted share (EPS) in fiscal year 2025. This represents an increase of 14.8% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$336.2M
YoY+7.6%

Iovance Biotherp recorded an outflow of $336.2M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents an increase of 7.6% from the prior year.

Cash & Debt
$163.1M
YoY+41.0%
5Y CAGR+19.4%
10Y CAGR+17.1%

Iovance Biotherp held $163.1M in cash as of fiscal year 2025; long-term debt is not reported for that period.

Shares Outstanding
412M
YoY+25.6%
5Y CAGR+22.9%
10Y CAGR+23.8%

Iovance Biotherp had 412M shares outstanding in fiscal year 2025. This represents an increase of 25.6% from the prior year.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Gross Margin
34.3%
YoY-8.9pp

Iovance Biotherp's gross margin was 34.3% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. This is down 8.9 percentage points from the prior year.

Return on Equity
-56.0%
YoY-3.6pp
5Y CAGR-16.4pp
10Y CAGR-29.4pp

Iovance Biotherp's ROE was -56.0% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is down 3.6 percentage points from the prior year.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$300.3M
YoY+8.7%
5Y CAGR+8.3%
10Y CAGR+34.5%

Iovance Biotherp invested $300.3M in research and development in fiscal year 2025. This represents an increase of 8.7% from the prior year.

Capital Expenditures
$33.8M
YoY+205.7%
5Y CAGR-6.3%
10Y CAGR+40.3%

Iovance Biotherp invested $33.8M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 205.7% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

IOVA Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

IOVA quarterly income statement
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Revenue$99.3M+39.0%$71.4M-17.7%$86.8M+28.6%$67.5M+12.5%$60.0M+21.5%$49.3M-33.1%$73.7M+25.9%$58.6M
Cost of Revenue$43.6M+2.6%$42.5M-1.4%$43.1M+12.0%$38.5M-21.3%$48.9M+14.4%$42.7M+84.9%$23.1M-26.7%$31.5M
Gross Profit$55.7M+92.6%$28.9M-33.7%$43.7M+50.7%$29.0M+161.7%$11.1M+67.5%$6.6M-86.9%$50.6M+87.1%$27.0M
R&D Expenses$58.9M-5.8%$62.5M-12.2%$71.2M-5.3%$75.2M-3.5%$77.9M+2.6%$76.0M+12.8%$67.3M+0.4%$67.0M
SG&A Expenses$39.3M+0.8%$38.9M+7.0%$36.4M+5.3%$34.6M-8.0%$37.6M-14.2%$43.8M+4.4%$42.0M+6.7%$39.3M
Operating Income-$51.9M+36.0%-$81.0M-10.3%-$73.5M+22.6%-$94.9M+16.6%-$113.8M+6.1%-$121.2M-40.0%-$86.6M+2.8%-$89.1M
Income Tax-$1.4M-106.5%-$665K-461.4%$184K+107.7%-$2.4M-221.0%$2.0M+208.2%-$1.8M-218.0%$1.6M+202.5%-$1.5M
Net Income-$47.3M+40.1%-$79.0M-9.9%-$71.9M+21.2%-$91.3M+18.3%-$111.7M+3.9%-$116.2M-47.8%-$78.6M+5.9%-$83.5M
EPS (Diluted)-$0.11+42.1%-$0.19N/AN/A-$0.33+8.3%-$0.36-44.0%-$0.25+10.7%-$0.28

Not reported in any period shown, so not listed: Interest Expense.

IOVA Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

IOVA quarterly balance sheet
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Total Assets$915.5M-1.1%$925.7M+1.4%$913.2M+0.9%$904.9M-0.3%$907.4M-6.1%$966.7M+6.2%$910.4M-8.1%$991.1M
Current Assets$464.3M-0.5%$466.5M+5.4%$442.7M+3.2%$429.1M+1.6%$422.5M-17.6%$512.6M+12.2%$457.0M-8.3%$498.6M
Cash & Equivalents$110.8M-43.6%$196.5M+20.5%$163.1M+3.1%$158.1M+19.4%$132.5M-22.8%$171.7M+48.4%$115.7M-29.5%$164.2M
Inventory$55.6M-4.8%$58.4M+13.0%$51.7M-0.1%$51.7M+3.8%$49.8M-24.0%$65.5M+27.2%$51.5M+33.5%$38.6M
Accounts Receivable$102.1M+24.9%$81.8M-0.8%$82.4M+23.5%$66.8M+11.4%$59.9M-15.5%$70.9M+2.3%$69.3M+24.3%$55.8M
Total Liabilities$179.5M-12.0%$203.9M-5.0%$214.6M+5.9%$202.7M-3.0%$208.9M+5.1%$198.9M-0.6%$200.0M-8.1%$217.7M
Current Liabilities$106.8M-17.4%$129.4M-6.5%$138.4M+10.0%$125.8M-2.6%$129.2M+5.3%$122.7M+0.3%$122.3M+3.6%$118.1M
Total Equity$736.0M+2.0%$721.8M+3.3%$698.6M-0.5%$702.3M+0.5%$698.5M-9.0%$767.9M+8.1%$710.4M-8.2%$773.5M
Retained Earnings-$2.9B-1.7%-$2.9B-2.8%-$2.8B-2.7%-$2.7B-3.5%-$2.6B-4.5%-$2.5B-4.9%-$2.4B-3.4%-$2.3B

Not reported in any period shown, so not listed: Goodwill, Long-Term Debt.

IOVA Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

IOVA quarterly cash flow statement
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Operating Cash Flow-$60.8M+15.6%-$72.1M-37.1%-$52.6M+33.2%-$78.7M-16.7%-$67.4M+35.0%-$103.7M-41.5%-$73.3M-24.3%-$59.0M
Capital Expenditures$5.4M-17.7%$6.6M-29.1%$9.3M-14.1%$10.8M+45.3%$7.5M+20.1%$6.2M+49.0%$4.2M+82.2%$2.3M
Free Cash Flow-$66.3M+15.8%-$78.7M-27.1%-$61.9M+30.9%-$89.5M-19.5%-$74.9M+31.8%-$109.9M-41.9%-$77.5M-26.4%-$61.3M
Investing Cash Flow-$74.0M-749.9%$11.4M+1370.2%$775K-95.4%$17.0M+22.9%$13.8M-12.8%$15.9M-33.0%$23.7M+148.5%-$48.8M
Financing Cash Flow$49.3M-47.8%$94.3M+67.9%$56.2M-36.2%$88.1M+565.6%$13.2M-90.8%$143.3M+6106.8%$2.3M-94.5%$42.0M

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

IOVA Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

IOVA quarterly financial ratios
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Gross Margin56.1%+15.6pp40.5%-9.8pp50.3%+7.4pp43.0%+24.5pp18.5%+5.1pp13.4%-55.3pp68.7%+22.5pp46.2%
Operating Margin-52.3%-113.5%-84.7%-140.7%-189.8%-245.8%-117.5%-152.1%
Net Margin-47.6%-110.7%-82.9%-135.3%-186.3%-235.5%-106.6%-142.7%
Return on Equity-6.4%+4.5pp-10.9%-0.7pp-10.3%+2.7pp-13.0%+3.0pp-16.0%-0.9pp-15.1%-4.1pp-11.1%-0.3pp-10.8%
Return on Assets-5.2%+3.4pp-8.5%-0.7pp-7.9%+2.2pp-10.1%+2.2pp-12.3%-0.3pp-12.0%-3.4pp-8.6%-0.2pp-8.4%
Current Ratio4.34+0.7x3.60+0.4x3.20-0.2x3.41+0.1x3.27-0.9x4.18+0.4x3.74-0.5x4.22
Debt-to-Equity0.240.0x0.280.0x0.310.0x0.290.0x0.300.0x0.260.0x0.280.0x0.28
FCF Margin-66.7%-110.1%-71.3%-132.8%-125.0%-222.8%-105.1%-104.6%

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

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Frequently Asked Questions

What is Iovance Biotherp's annual revenue?

Iovance Biotherp (IOVA) reported $263.5M in total revenue for fiscal year 2025. This represents a 60.6% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Iovance Biotherp's revenue growing?

Iovance Biotherp (IOVA) revenue grew by 60.6% year-over-year, from $164.1M to $263.5M in fiscal year 2025.

Is Iovance Biotherp profitable?

No, Iovance Biotherp (IOVA) reported a net income of -$391.0M in fiscal year 2025.

Iovance Biotherp (IOVA) reported diluted earnings per share of -$1.09 for fiscal year 2025. This represents a 14.8% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Iovance Biotherp (IOVA) had EBITDA of -$390.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Iovance Biotherp (IOVA) had a gross margin of 34.3% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.

Iovance Biotherp (IOVA) has a return on equity of -56.0% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Iovance Biotherp (IOVA) recorded an outflow of $336.2M in free cash flow during fiscal year 2025. This represents a 7.6% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Iovance Biotherp (IOVA) recorded an outflow of $302.4M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Iovance Biotherp (IOVA) had $913.2M in total assets as of fiscal year 2025, including both current and long-term assets.

Iovance Biotherp (IOVA) invested $33.8M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Iovance Biotherp (IOVA) invested $300.3M in research and development during fiscal year 2025.

Iovance Biotherp (IOVA) had 412M shares outstanding as of fiscal year 2025.

Iovance Biotherp (IOVA) had a current ratio of 3.20 as of fiscal year 2025, which is generally considered healthy.

Iovance Biotherp (IOVA) had a debt-to-equity ratio of 0.31 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Iovance Biotherp (IOVA) had a return on assets of -42.8% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

At the end of fiscal year 2025, Iovance Biotherp (IOVA) held $297.0M in cash, cash equivalents and investments, and reported an operating cash outflow of $302.4M over that year. Dividing the one by the other, the reported balance equals about 12 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Iovance Biotherp (IOVA) has an Altman Z-Score of 5.12, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Iovance Biotherp (IOVA) has a Piotroski F-Score of 2 out of 8 computable signals; 1 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Iovance Biotherp (IOVA) reported a net loss of $391.0M while operations used $302.4M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Iovance Biotherp (IOVA) scores 60 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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