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Ispecimen Inc. Financials

ISPC
Source SEC Filings (10-K/10-Q) Data as of Mar 31, 2026 Currency USD FYE December

This page shows Ispecimen Inc. (ISPC) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ISPC FY2025

iSpecimen is funding operations externally while current-scale revenue contributes almost nothing after direct service costs.

In FY2025, gross margin collapsed to 1.3% while free cash burn stayed near operating cash burn at -$4.2M, showing the drain is coming from weak current operations rather than heavy reinvestment. Cash ended at $6.9M only because financing supplied $10.2M, so the improvement in near-term liquidity came from outside capital, not from a self-funding model.

The revenue drop to $1.9M mattered because it left direct service economics almost flat: with gross profit of just $24K, overhead cuts could shrink the operating loss without meaningfully improving what each sale contributes. That makes the smaller operating loss look more like cost compression than a recovery in underlying business efficiency.

This is now an asset-light cash burn story, not a capex story. Capital spending was only $454, so free cash flow closely tracked operating cash flow and reported losses are showing up as real cash use. With the current ratio back to 1.1x but debt-to-equity still at 2.1x, liquidity looks recently repaired rather than internally rebuilt.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&D Intensity Revenue Progress Burn Trend Balance Sheet 46 / 100
Financial Health Score 46/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Ispecimen Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
53
Dilution
83
Revenue Progress
4
Burn Trend
56
Balance Sheet
77
Altman Z-Score Distress
-14.61

Ispecimen Inc. scores -14.61, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($3.2M) relative to total liabilities ($6.4M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
4/8

Ispecimen Inc. passes 4 of 8 computable financial strength tests (1 of the nine could not be computed from available data). 2 of 4 profitability signals pass, all 2 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality Low Quality
0.40x

For every $1 of reported earnings, Ispecimen Inc. generates $0.40 in operating cash flow (-$4.2M OCF vs -$10.5M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Interest Coverage At Risk
-4606.4x

Ispecimen Inc. earns $-4606.4 in operating income for every $1 of interest expense (-$9.0M vs $2K). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$1.9M
YoY-79.2%
5Y CAGR-25.1%

Ispecimen Inc. generated $1.9M in revenue in fiscal year 2025. This represents a decrease of 79.2% from the prior year.

EBITDA
-$7.2M
YoY+30.5%

Ispecimen Inc.'s EBITDA was -$7.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 30.5% from the prior year.

Net Income
-$10.5M
YoY+16.1%

Ispecimen Inc. reported -$10.5M in net income in fiscal year 2025. This represents an increase of 16.1% from the prior year.

EPS (Diluted)
$-2.28
YoY+87.0%

Ispecimen Inc. earned $-2.28 per diluted share (EPS) in fiscal year 2025. This represents an increase of 87.0% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$4.2M
YoY+48.9%

Ispecimen Inc. generated -$4.2M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 48.9% from the prior year.

Cash & Debt
$6.9M
YoY+266.3%
5Y CAGR+58.1%

Ispecimen Inc. held $6.9M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
211,965
YoY-87.5%

Ispecimen Inc. had 211,965 shares outstanding in fiscal year 2025. This represents a decrease of 87.5% from the prior year.

Margins & Returns

Gross Margin
1.3%
YoY-41.7pp
5Y CAGR-54.9pp

Ispecimen Inc.'s gross margin was 1.3% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. This is down 41.7 percentage points from the prior year.

Operating Margin
-465.4%
YoY-328.4pp
5Y CAGR-436.0pp

Ispecimen Inc.'s operating margin was -465.4% in fiscal year 2025, reflecting core business profitability. This is down 328.4 percentage points from the prior year.

Net Margin
-543.7%
YoY-409.2pp
5Y CAGR-486.8pp

Ispecimen Inc.'s net profit margin was -543.7% in fiscal year 2025, showing the share of revenue converted to profit. This is down 409.2 percentage points from the prior year.

Return on Equity
-339.6%
YoY+37.9pp

Ispecimen Inc.'s ROE was -339.6% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 37.9 percentage points from the prior year.

Capital Allocation

R&D Spending
N/A
Share Buybacks
N/A
Capital Expenditures
$454
YoY-98.6%
5Y CAGR+1.3%

Ispecimen Inc. invested $454 in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 98.6% from the prior year.

ISPC Income Statement

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Revenue $156K+201.4% $52K-51.4% $107K-85.1% $713K-32.6% $1.1M-28.3% $1.5M-44.6% $2.7M-7.0% $2.9M
Cost of Revenue $84K-85.9% $599K+192.7% $205K-53.9% $444K-32.4% $657K-50.4% $1.3M-14.8% $1.6M+9.1% $1.4M
Gross Profit $72K+113.1% -$547K-458.2% -$98K-136.4% $269K-32.8% $400K+164.4% $151K-86.3% $1.1M-23.0% $1.4M
R&D Expenses N/A N/A N/A N/A N/A N/A N/A N/A
SG&A Expenses $680K-24.5% $901K+4.3% $864K-8.9% $948K+25.0% $759K-62.4% $2.0M+125.7% $893K-15.4% $1.1M
Operating Income -$2.5M+5.6% -$2.7M+5.0% -$2.8M-55.4% -$1.8M-11.2% -$1.6M+71.9% -$5.8M-242.5% -$1.7M+21.8% -$2.2M
Interest Expense N/A N/A $2 N/A $2K-98.8% $157K+2038.3% $7K+64.6% $4K
Income Tax N/A N/A N/A N/A N/A N/A N/A N/A
Net Income -$2.3M+54.5% -$5.0M-79.9% -$2.8M-165.5% -$1.0M+36.9% -$1.7M+72.6% -$6.0M-320.0% -$1.4M+31.7% -$2.1M
EPS (Diluted) $-6.66 N/A $-0.48-14.3% $-0.42+98.5% $-28.55 N/A $-2.10 $-3.72

ISPC Balance Sheet

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Total Assets $6.6M-30.7% $9.5M+5.9% $9.0M+49.1% $6.0M-11.8% $6.8M-26.8% $9.4M-17.0% $11.3M-5.4% $11.9M
Current Assets $3.5M-49.9% $7.0M+93.1% $3.6M+208.9% $1.2M-23.7% $1.5M-57.4% $3.6M-23.0% $4.7M-11.0% $5.2M
Cash & Equivalents $2.8M-59.0% $6.9M+147.3% $2.8M+372.6% $589K-24.8% $783K-58.3% $1.9M+7.2% $1.8M-18.6% $2.2M
Inventory N/A N/A N/A N/A N/A $45K N/A N/A
Accounts Receivable $133K+175.1% $48K-60.1% $121K-67.5% $372K-36.0% $582K-59.7% $1.4M+48.3% $974K+9.1% $893K
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $5.8M-10.1% $6.4M+8.7% $5.9M+9.5% $5.4M+4.6% $5.2M-14.3% $6.0M-7.8% $6.5M+12.7% $5.8M
Current Liabilities $5.6M-10.1% $6.2M+9.4% $5.7M+10.2% $5.2M+5.1% $4.9M-14.7% $5.8M-7.9% $6.3M+7.8% $5.8M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $814K-73.6% $3.1M+0.5% $3.1M+394.0% $622K-62.7% $1.7M-49.6% $3.3M-29.8% $4.7M-22.6% $6.1M
Retained Earnings -$84.6M-2.8% -$82.4M-6.5% -$77.3M-3.7% -$74.6M-1.4% -$73.5M-2.3% -$71.9M-9.2% -$65.8M-2.2% -$64.4M

ISPC Cash Flow Statement

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Operating Cash Flow -$3.4M-266.6% -$917K+55.0% -$2.0M-958.9% -$192K+82.5% -$1.1M+69.3% -$3.6M-231.0% -$1.1M+29.9% -$1.5M
Capital Expenditures N/A $0 $0 N/A N/A $8K-45.9% $15K $0
Free Cash Flow N/A -$917K+55.0% -$2.0M N/A N/A -$3.6M-227.3% -$1.1M+28.9% -$1.5M
Investing Cash Flow -$700K $0+100.0% -$1.0M N/A N/A -$73K+59.4% -$180K-161.0% $295K
Financing Cash Flow N/A $5.0M-4.1% $5.2M N/A N/A $3.8M+338.6% $860K-34.1% $1.3M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A $0 $0

ISPC Financial Ratios

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Gross Margin 45.9%+1102.8pp -1056.9%-965.0pp -91.9%-129.7pp 37.7%-0.1pp 37.9%+27.6pp 10.3%-31.4pp 41.6%-8.6pp 50.3%
Operating Margin -1627.1%+3565.8pp -5192.9%-2537.7pp -2655.2%-2399.8pp -255.4%-100.5pp -154.9%+240.9pp -395.8%-331.8pp -64.1%+12.1pp -76.2%
Net Margin -1458.4%+8203.8pp -9662.2%-7053.5pp -2608.7%-2461.8pp -146.8%+10.0pp -156.8%+253.0pp -409.8%-355.7pp -54.1%+19.6pp -73.7%
Return on Equity -279.5%-117.6pp -161.9%-71.5pp -90.5%+77.9pp -168.4%-69.0pp -99.4%+83.2pp -182.6%-152.1pp -30.5%+4.1pp -34.6%
Return on Assets -34.4%+18.1pp -52.5%-21.6pp -30.9%-13.6pp -17.3%+6.9pp -24.2%+40.4pp -64.7%-51.9pp -12.8%+4.9pp -17.7%
Current Ratio 0.62-0.5 1.12+0.5 0.63+0.4 0.23-0.1 0.31-0.3 0.62-0.1 0.74-0.2 0.90
Debt-to-Equity 7.12+5.0 2.09+0.2 1.93-6.8 8.70+5.6 3.10+1.3 1.82+0.4 1.39+0.4 0.95
FCF Margin N/A -1771.5%+138.3pp -1909.7% N/A N/A -242.7%-201.6pp -41.1%+12.7pp -53.8%

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Frequently Asked Questions

Ispecimen Inc. (ISPC) reported $1.9M in total revenue for fiscal year 2025. This represents a -79.2% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Ispecimen Inc. (ISPC) revenue declined by 79.2% year-over-year, from $9.3M to $1.9M in fiscal year 2025.

No, Ispecimen Inc. (ISPC) reported a net income of -$10.5M in fiscal year 2025, with a net profit margin of -543.7%.

Ispecimen Inc. (ISPC) reported diluted earnings per share of $-2.28 for fiscal year 2025. This represents a 87.0% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Ispecimen Inc. (ISPC) had EBITDA of -$7.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Ispecimen Inc. (ISPC) had a gross margin of 1.3% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.

Ispecimen Inc. (ISPC) had an operating margin of -465.4% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Ispecimen Inc. (ISPC) had a net profit margin of -543.7% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Ispecimen Inc. (ISPC) has a return on equity of -339.6% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Ispecimen Inc. (ISPC) generated -$4.2M in free cash flow during fiscal year 2025. This represents a 48.9% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Ispecimen Inc. (ISPC) generated -$4.2M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Ispecimen Inc. (ISPC) had $9.5M in total assets as of fiscal year 2025, including both current and long-term assets.

Ispecimen Inc. (ISPC) invested $454 in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Ispecimen Inc. (ISPC) had 211,965 shares outstanding as of fiscal year 2025.

Ispecimen Inc. (ISPC) had a current ratio of 1.12 as of fiscal year 2025, which is considered adequate.

Ispecimen Inc. (ISPC) had a debt-to-equity ratio of 2.09 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Ispecimen Inc. (ISPC) had a return on assets of -110.0% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Ispecimen Inc. (ISPC) had $6.9M in cash against an annual operating cash burn of $4.2M. This gives an estimated cash runway of approximately 19 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Ispecimen Inc. (ISPC) has an Altman Z-Score of -14.61, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Ispecimen Inc. (ISPC) has a Piotroski F-Score of 4 out of 8 computable signals; 1 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Ispecimen Inc. (ISPC) has an earnings quality ratio of 0.40x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Ispecimen Inc. (ISPC) has an interest coverage ratio of -4606.4x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Ispecimen Inc. (ISPC) scores 46 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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