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Ispecimen Inc. Financials

ISPC
Source SEC Filings (10-K/10-Q) Updated Mar 31, 2026 Currency USD FYE December

This page shows Ispecimen Inc. (ISPC) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ISPC FY2025

iSpecimen is funding operations externally while current-scale revenue contributes almost nothing after direct service costs.

In FY2025, gross margin collapsed to 1.3% while free cash burn stayed near operating cash burn at -$4.2M, showing the drain is coming from weak current operations rather than heavy reinvestment. Cash ended at $6.9M only because financing supplied $10.2M, so the improvement in near-term liquidity came from outside capital, not from a self-funding model.

The revenue drop to $1.9M mattered because it left direct service economics almost flat: with gross profit of just $24K, overhead cuts could shrink the operating loss without meaningfully improving what each sale contributes. That makes the smaller operating loss look more like cost compression than a recovery in underlying business efficiency.

This is now an asset-light cash burn story, not a capex story. Capital spending was only $454, so free cash flow closely tracked operating cash flow and reported losses are showing up as real cash use. With the current ratio back to 1.1x but debt-to-equity still at 2.1x, liquidity looks recently repaired rather than internally rebuilt.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 13 / 100
Financial Profile 13/100

Based on FY2025 annual data, averaged across the last 3 years for performance metrics (most-recent year weighted highest). How this score is calculated →

Health score ≠ stock price. This rates the quality of Ispecimen Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Profitability
0

Ispecimen Inc. has an operating margin of -465.4%, meaning the company retains $-465 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses. This is down from -137.0% the prior year.

Growth
0

Ispecimen Inc.'s revenue declined 79.2% year-over-year, from $9.3M to $1.9M. This contraction results in a growth score of 0/100.

Leverage
59

Ispecimen Inc. has a moderate D/E ratio of 2.09. This balance of debt and equity financing earns a leverage score of 59/100.

Liquidity
17

Ispecimen Inc.'s current ratio of 1.12 is below the typical benchmark, resulting in a score of 17/100. However, the company holds substantial cash reserves (110% of current liabilities), which buffers actual liquidity risk. Large mature operators often run tight current ratios by design.

Cash Flow
0

While Ispecimen Inc. generated -$4.2M in operating cash flow, capex of $454 consumed most of it, leaving -$4.2M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.

Returns
0

Ispecimen Inc. generates a -339.6% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100. This is up from -377.5% the prior year.

Piotroski F-Score Neutral
4/9

Ispecimen Inc. passes 4 of 9 financial strength tests. 2 of 4 profitability signals pass, 2 of 3 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality Low Quality
0.40x

For every $1 of reported earnings, Ispecimen Inc. generates $0.40 in operating cash flow (-$4.2M OCF vs -$10.5M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Interest Coverage At Risk
-4606.4x

Ispecimen Inc. earns $-4606.4 in operating income for every $1 of interest expense (-$9.0M vs $2K). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$1.9M
YoY-79.2%
5Y CAGR-25.1%

Ispecimen Inc. generated $1.9M in revenue in fiscal year 2025. This represents a decrease of 79.2% from the prior year.

EBITDA
-$7.2M
YoY+30.5%

Ispecimen Inc.'s EBITDA was -$7.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 30.5% from the prior year.

Net Income
-$10.5M
YoY+16.1%

Ispecimen Inc. reported -$10.5M in net income in fiscal year 2025. This represents an increase of 16.1% from the prior year.

EPS (Diluted)
$-2.28
YoY+87.0%

Ispecimen Inc. earned $-2.28 per diluted share (EPS) in fiscal year 2025. This represents an increase of 87.0% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$4.2M
YoY+48.9%

Ispecimen Inc. generated -$4.2M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 48.9% from the prior year.

Cash & Debt
$6.9M
YoY+266.3%
5Y CAGR+58.1%

Ispecimen Inc. held $6.9M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
211,965
YoY-87.5%

Ispecimen Inc. had 211,965 shares outstanding in fiscal year 2025. This represents a decrease of 87.5% from the prior year.

Margins & Returns

Gross Margin
1.3%
YoY-41.7pp
5Y CAGR-54.9pp

Ispecimen Inc.'s gross margin was 1.3% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. This is down 41.7 percentage points from the prior year.

Operating Margin
-465.4%
YoY-328.4pp
5Y CAGR-436.0pp

Ispecimen Inc.'s operating margin was -465.4% in fiscal year 2025, reflecting core business profitability. This is down 328.4 percentage points from the prior year.

Net Margin
-543.7%
YoY-409.2pp
5Y CAGR-486.8pp

Ispecimen Inc.'s net profit margin was -543.7% in fiscal year 2025, showing the share of revenue converted to profit. This is down 409.2 percentage points from the prior year.

Return on Equity
-339.6%
YoY+37.9pp

Ispecimen Inc.'s ROE was -339.6% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 37.9 percentage points from the prior year.

Capital Allocation

R&D Spending
N/A
Share Buybacks
N/A
Capital Expenditures
$454
YoY-98.6%
5Y CAGR+1.3%

Ispecimen Inc. invested $454 in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 98.6% from the prior year.

ISPC Income Statement

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Revenue $156K+201.4% $52K-51.4% $107K-85.1% $713K-32.6% $1.1M-28.3% $1.5M-44.6% $2.7M-7.0% $2.9M
Cost of Revenue $84K-85.9% $599K+192.7% $205K-53.9% $444K-32.4% $657K-50.4% $1.3M-14.8% $1.6M+9.1% $1.4M
Gross Profit $72K+113.1% -$547K-458.2% -$98K-136.4% $269K-32.8% $400K+164.4% $151K-86.3% $1.1M-23.0% $1.4M
R&D Expenses N/A N/A N/A N/A N/A N/A N/A N/A
SG&A Expenses $680K-24.5% $901K+4.3% $864K-8.9% $948K+25.0% $759K-62.4% $2.0M+125.7% $893K-15.4% $1.1M
Operating Income -$2.5M+5.6% -$2.7M+5.0% -$2.8M-55.4% -$1.8M-11.2% -$1.6M+71.9% -$5.8M-242.5% -$1.7M+21.8% -$2.2M
Interest Expense N/A N/A $2 N/A $2K-98.8% $157K+2038.3% $7K+64.6% $4K
Income Tax N/A N/A N/A N/A N/A N/A N/A N/A
Net Income -$2.3M+54.5% -$5.0M-79.9% -$2.8M-165.5% -$1.0M+36.9% -$1.7M+72.6% -$6.0M-320.0% -$1.4M+31.7% -$2.1M
EPS (Diluted) $-6.66 N/A $-0.48-14.3% $-0.42+98.5% $-28.55 N/A $-2.10 $-3.72

ISPC Balance Sheet

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Total Assets $6.6M-30.7% $9.5M+5.9% $9.0M+49.1% $6.0M-11.8% $6.8M-26.8% $9.4M-17.0% $11.3M-5.4% $11.9M
Current Assets $3.5M-49.9% $7.0M+93.1% $3.6M+208.9% $1.2M-23.7% $1.5M-57.4% $3.6M-23.0% $4.7M-11.0% $5.2M
Cash & Equivalents $2.8M-59.0% $6.9M+147.3% $2.8M+372.6% $589K-24.8% $783K-58.3% $1.9M+7.2% $1.8M-18.6% $2.2M
Inventory N/A N/A N/A N/A N/A $45K N/A N/A
Accounts Receivable $133K+175.1% $48K-60.1% $121K-67.5% $372K-36.0% $582K-59.7% $1.4M+48.3% $974K+9.1% $893K
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $5.8M-10.1% $6.4M+8.7% $5.9M+9.5% $5.4M+4.6% $5.2M-14.3% $6.0M-7.8% $6.5M+12.7% $5.8M
Current Liabilities $5.6M-10.1% $6.2M+9.4% $5.7M+10.2% $5.2M+5.1% $4.9M-14.7% $5.8M-7.9% $6.3M+7.8% $5.8M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $814K-73.6% $3.1M+0.5% $3.1M+394.0% $622K-62.7% $1.7M-49.6% $3.3M-29.8% $4.7M-22.6% $6.1M
Retained Earnings -$84.6M-2.8% -$82.4M-6.5% -$77.3M-3.7% -$74.6M-1.4% -$73.5M-2.3% -$71.9M-9.2% -$65.8M-2.2% -$64.4M

ISPC Cash Flow Statement

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Operating Cash Flow -$3.4M-266.6% -$917K+55.0% -$2.0M-958.9% -$192K+82.5% -$1.1M+69.3% -$3.6M-231.0% -$1.1M+29.9% -$1.5M
Capital Expenditures N/A $0 $0 N/A N/A $8K-45.9% $15K $0
Free Cash Flow N/A -$917K+55.0% -$2.0M N/A N/A -$3.6M-227.3% -$1.1M+28.9% -$1.5M
Investing Cash Flow -$700K $0+100.0% -$1.0M N/A N/A -$73K+59.4% -$180K-161.0% $295K
Financing Cash Flow N/A $5.0M-4.1% $5.2M N/A N/A $3.8M+338.6% $860K-34.1% $1.3M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A $0 $0

ISPC Financial Ratios

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Gross Margin 45.9%+1102.8pp -1056.9%-965.0pp -91.9%-129.7pp 37.7%-0.1pp 37.9%+27.6pp 10.3%-31.4pp 41.6%-8.6pp 50.3%
Operating Margin -1627.1%+3565.8pp -5192.9%-2537.7pp -2655.2%-2399.8pp -255.4%-100.5pp -154.9%+240.9pp -395.8%-331.8pp -64.1%+12.1pp -76.2%
Net Margin -1458.4%+8203.8pp -9662.2%-7053.5pp -2608.7%-2461.8pp -146.8%+10.0pp -156.8%+253.0pp -409.8%-355.7pp -54.1%+19.6pp -73.7%
Return on Equity -279.5%-117.6pp -161.9%-71.5pp -90.5%+77.9pp -168.4%-69.0pp -99.4%+83.2pp -182.6%-152.1pp -30.5%+4.1pp -34.6%
Return on Assets -34.4%+18.1pp -52.5%-21.6pp -30.9%-13.6pp -17.3%+6.9pp -24.2%+40.4pp -64.7%-51.9pp -12.8%+4.9pp -17.7%
Current Ratio 0.62-0.5 1.12+0.5 0.63+0.4 0.23-0.1 0.31-0.3 0.62-0.1 0.74-0.2 0.90
Debt-to-Equity 7.12+5.0 2.09+0.2 1.93-6.8 8.70+5.6 3.10+1.3 1.82+0.4 1.39+0.4 0.95
FCF Margin N/A -1771.5%+138.3pp -1909.7% N/A N/A -242.7%-201.6pp -41.1%+12.7pp -53.8%

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Frequently Asked Questions

Ispecimen Inc. (ISPC) reported $1.9M in total revenue for fiscal year 2025. This represents a -79.2% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Ispecimen Inc. (ISPC) revenue declined by 79.2% year-over-year, from $9.3M to $1.9M in fiscal year 2025.

No, Ispecimen Inc. (ISPC) reported a net income of -$10.5M in fiscal year 2025, with a net profit margin of -543.7%.

Ispecimen Inc. (ISPC) reported diluted earnings per share of $-2.28 for fiscal year 2025. This represents a 87.0% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Ispecimen Inc. (ISPC) had EBITDA of -$7.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Ispecimen Inc. (ISPC) had a gross margin of 1.3% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.

Ispecimen Inc. (ISPC) had an operating margin of -465.4% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Ispecimen Inc. (ISPC) had a net profit margin of -543.7% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Ispecimen Inc. (ISPC) has a return on equity of -339.6% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Ispecimen Inc. (ISPC) generated -$4.2M in free cash flow during fiscal year 2025. This represents a 48.9% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Ispecimen Inc. (ISPC) generated -$4.2M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Ispecimen Inc. (ISPC) had $9.5M in total assets as of fiscal year 2025, including both current and long-term assets.

Ispecimen Inc. (ISPC) invested $454 in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Ispecimen Inc. (ISPC) had 211,965 shares outstanding as of fiscal year 2025.

Ispecimen Inc. (ISPC) had a current ratio of 1.12 as of fiscal year 2025, which is considered adequate.

Ispecimen Inc. (ISPC) had a debt-to-equity ratio of 2.09 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Ispecimen Inc. (ISPC) had a return on assets of -110.0% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Ispecimen Inc. (ISPC) had $6.9M in cash against an annual operating cash burn of $4.2M. This gives an estimated cash runway of approximately 19 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Ispecimen Inc. (ISPC) has a Piotroski F-Score of 4 out of 9, indicating neutral financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Ispecimen Inc. (ISPC) has an earnings quality ratio of 0.40x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Ispecimen Inc. (ISPC) has an interest coverage ratio of -4606.4x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Ispecimen Inc. (ISPC) scores 13 out of 100 on our Financial Profile, indicating weak overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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