What is PROTOKINETIX INC's earnings per share (EPS)?

PROTOKINETIX INC (PKTX) reported diluted earnings per share of $0.00 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

PROTOKINETIX INC (PKTX) Financials

PKTX

FY2025 annual

Revenue Not reported for FY2025

Net Income -$394K -8.1% YoY

EPS (Diluted) $0.00 YoY not available

Operating Cash Flow -$135K +39.3% YoY

Market Cap $82K as of Sep 4, 2026

Price / Sales n/m no revenue reported

Price / Earnings n/m net loss, so no earnings multiple, FY2025

Price / Book 0.3x on $298K equity, Q4 FY2025

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Sep 4, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings (10-K/10-Q) Latest period FY2025, ended Dec 31, 2025 Reported Sep 3, 2026 Currency USD FYE December

Newest figures come from the 10-K for FY2025, filed Sep 3, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the PKTX SEC filings page.

This page shows PROTOKINETIX INC (PKTX) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 15 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI PKTX FY2025 2026-09-03

The business relies on recurring financing inflows while operating cash remains negative and liabilities rise against a shrinking equity base.

The key pattern is a partial cash-flow improvement without self-funding: operating cash flow improved from -$376K in FY2023 to -$135K in FY2025, yet financing cash flow remained positive at $198K in FY2025. That pairing indicates operating needs were still being met through financing rather than internally generated cash, while the reported liquidity comparison stood at 0.1 months of annual operating outflow.

Liabilities climbed from $124K in FY2024 to $185K in FY2025, while equity fell over the same period. That combination lifted debt-to-equity from 0.4x to 0.6x, making the capital structure more liability-dependent rather than merely loss-making.

R&D was $107K versus SG&A of $58K in FY2025, and R&D exceeded SG&A in every reported year, indicating a development-led cost base. Shares outstanding increased from 347M in FY2023 to 407M in FY2025, so financing activity occurred alongside a substantially larger equity count.

Financial Health Signals

Financial health score not available

PROTOKINETIX INC does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.

Piotroski F-Score Partial

1/5

PROTOKINETIX INC passes 1 of 5 computable financial strength tests (4 of the nine could not be computed from available data). 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution).

Earnings Quality No Cash Backing

N/A

PROTOKINETIX INC reported a net loss of $394K while operations used $135K of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

EPS (Diluted)

$0.00

PROTOKINETIX INC earned $0.00 per diluted share (EPS) in Q4 2025.

Revenue

Not reported for Q4 2025.

EBITDA

Not reported for Q4 2025.

Net Income

Not reported for Q4 2025.

Cash & Balance Sheet

Cash & Debt

$1K

YoY-76.2%

QoQ+84.2%

5Y CAGR-64.3%

10Y CAGR-44.0%

PROTOKINETIX INC held $1K in cash as of Q4 2025; long-term debt is not reported for that period.

Shares Outstanding

407M

YoY+7.7%

QoQ+3.9%

5Y CAGR+7.1%

PROTOKINETIX INC had 407M shares outstanding in Q4 2025. This represents an increase of 7.7% from the same quarter a year earlier. Against the prior quarter it is up 3.9%.

Free Cash Flow

Not reported for Q4 2025.

Dividends Per Share

Not reported for Q4 2025.

Margins & Returns

None of these metrics is reported for Q4 2025.

Capital Allocation

None of these metrics is reported for Q4 2025.

PKTX Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

PKTX quarterly income statement

Metric	FY2510-K	FY2410-K	FY2310-K	FY2210-K	FY2110-K	FY2010-K	FY1910-K	FY1810-K	FY1710-K	FY1610-K	FY1510-K	FY1410-K	FY1310-K	FY1210-K	FY1110-K
Revenue	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	$0	$0	$0	$0
R&D Expenses	$107K+7.0%	$100K-11.4%	$112K-74.9%	$449K+3.0%	$436K-17.3%	$527K+42.7%	$370K+9.6%	$337K+13.7%	$297K-34.2%	$451K+183.8%	$159K+1055.6%	$14K-81.5%	$75K	$0-100.0%	$117K
SG&A Expenses	$58K-5.4%	$61K-38.3%	$100K-38.8%	$163K-48.7%	$317K+51.7%	$209K-25.5%	$280K+259.2%	$78K-25.8%	$105K+5.6%	$100K-21.4%	$127K	N/A	$96K	N/A	N/A
Interest Expense	N/A	N/A	N/A	N/A	N/A	N/A	$0-100.0%	$306-81.5%	$2K+13708.3%	$12-99.7%	$4K	N/A	$26K+10.0%	$24K+100.0%	$12K
Income Tax	$0	$0	$0	N/A	$0	$0	$0	$0	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Net Income	-$394K-8.1%	-$364K+12.3%	-$415K+78.2%	-$1.9M	N/A	N/A	N/A	-$1.2M+19.6%	-$1.5M+0.7%	-$1.5M-21.5%	-$1.3M	N/A	N/A	N/A	N/A
EPS (Basic)	$0.00	$0.00+100.0%	-$0.010.0%	-$0.01	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
EPS (Diluted)	$0.00	$0.00+100.0%	-$0.01	-$0.01	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Diluted Shares (Avg)	386M+7.7%	359M+7.6%	333M	307M+5.3%	292M+4.8%	279M+3.6%	269M+5.0%	256M+3.9%	247M+11.3%	222M+11.9%	198M+14.8%	172M+25.7%	137M+6.1%	129M+38.1%	94M

Metric	Q4'2510-K	Q3'2510-Q	Q2'2510-Q	Q1'2510-Q	Q4'2410-K	Q3'2410-Q	Q2'2410-Q	Q1'2410-Q
R&D Expenses	N/A	$24K+15.2%	$24K+16.2%	$34K-7.7%	N/A	$21K-1.4%	$21K-34.3%	$37K+61.5%
SG&A Expenses	N/A	$16K-0.1%	$14K+6.8%	$15K+4.4%	N/A	$16K-1.7%	$13K-63.0%	$14K-56.9%
Net Income	N/A	-$85K-0.4%	-$91K-7.0%	-$98K-6.2%	N/A	-$85K-5.2%	-$85K+26.4%	-$92K+14.0%
EPS (Basic)	$0.00	$0.00	$0.00	$0.00	$0.00+100.0%	$0.00+100.0%	$0.00+100.0%	$0.00+100.0%
EPS (Diluted)	$0.00	$0.00	$0.00	$0.00	$0.00+100.0%	$0.00+100.0%	$0.00+100.0%	$0.00+100.0%
Diluted Shares (Avg)	N/A	389M+6.7%	354M0.0%	374M+12.3%	N/A	365M+8.7%	354M+5.5%	333M+2.3%

Not reported in any period shown, so not listed: Revenue, Cost of Revenue, Gross Profit, Operating Income, EBITDA, Interest Expense, Income Tax.

PKTX Balance Sheet

PKTX quarterly balance sheet

Metric	FY2510-K	FY2410-K	FY2310-K	FY2210-K	FY2110-K	FY2010-K	FY1910-K	FY1810-K	FY1710-K	FY1610-K	FY1510-K	FY1410-K	FY1310-K	FY1210-K	FY1110-K
Total Assets	$483K+3.7%	$466K-3.0%	$481K+3.8%	$463K+3.7%	$446K-4.9%	$469K-19.9%	$586K+80.4%	$325K-37.3%	$518K-4.4%	$542K+20.5%	$450K+7635.7%	$6K-76.4%	$25K+192.5%	$8K-71.7%	$30K
Current Assets	N/A	N/A	$21K-19.3%	$27K-68.2%	$84K-57.0%	$194K-48.6%	$378K+176.0%	$137K-62.5%	$365K-17.3%	$441K+16.3%	$379K+6427.2%	$6K	N/A	N/A	N/A
Cash & Equivalents	$1K-76.2%	$5K-77.0%	$20K-20.1%	$26K-55.6%	$58K-70.2%	$193K-48.7%	$377K+177.4%	$136K-55.1%	$303K-18.4%	$371K0.0%	$371K+116957.4%	$317-89.7%	$3K+27.4%	$2K-46.7%	$5K
Short-Term Investments	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
Accounts Receivable	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	$0-100.0%	$8K+46.0%	$5K+4519.3%	$119-98.0%	$6K-7.8%	$7K
Long-Term Investments	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
Total Liabilities	$185K+49.5%	$124K+177.5%	$45K+7.6%	$42K-55.5%	$93K+107.5%	$45K+76.2%	$26K-67.6%	$79K-45.4%	$145K+219.2%	$45K-0.2%	$45K-89.5%	$434K-32.5%	$643K+24.6%	$516K+5.3%	$490K
Current Liabilities	$185K+49.5%	$124K+177.5%	$45K+7.6%	$42K-55.5%	$93K+107.5%	$45K	$0-100.0%	$79K-45.4%	$145K+219.2%	$45K-0.2%	$45K	N/A	N/A	N/A	N/A
Non-Current Liabilities	$0	$0	$0	$0	$0	$0-100.0%	$26K	$0	$0	$0	$0	N/A	N/A	N/A	N/A
Total Equity	$298K-12.9%	$342K-21.5%	$436K+3.4%	$421K+19.4%	$353K-16.8%	$424K-24.3%	$560K+127.8%	$246K-34.2%	$374K-24.8%	$497K+22.9%	$404K+194.4%	-$428K+30.7%	-$618K-21.8%	-$507K-10.2%	-$460K
Retained Earnings	-$48.6M-0.8%	-$48.2M-0.8%	-$47.9M-0.9%	-$47.4M-4.2%	-$45.5M-5.4%	-$43.2M-21.5%	-$35.5M-13.4%	-$31.4M-4.0%	-$30.1M-5.3%	-$28.6M-5.6%	-$27.1M-4.9%	-$25.8M-0.7%	-$25.7M	N/A	N/A

Metric	Q4'2510-K	Q3'2510-Q	Q2'2510-Q	Q1'2510-Q	Q4'2410-K	Q3'2410-Q	Q2'2410-Q	Q1'2410-Q
Total Assets	$483K+3.7%	$478K-0.3%	$474K+0.2%	$529K+14.6%	$466K-3.0%	$479K+6.3%	$474K+1.4%	$461K+3.2%
Current Assets	N/A	N/A	N/A	N/A	N/A	$7K-49.9%	$3K-83.5%	$4K-51.4%
Cash & Equivalents	$1K-76.2%	$607-89.3%	$112-94.9%	$49K+1644.6%	$5K-77.0%	$6K-54.1%	$2K-88.2%	$3K-59.1%
Short-Term Investments	$0	$0	$0	$0	$0	$0	$0	$0
Long-Term Investments	$0	$0	$0	$0	$0	$0	$0	$0
Total Liabilities	$185K+49.5%	$227K+158.9%	$149K+153.7%	$152K+125.3%	$124K+177.5%	$88K+598.5%	$59K+343.4%	$68K+27.5%
Current Liabilities	$185K+49.5%	$227K+158.9%	$149K+153.7%	$152K+125.3%	$124K+177.5%	$88K+598.5%	$59K+343.4%	$68K+27.5%
Non-Current Liabilities	$0	$0	$0	$0	$0	$0	$0	$0
Total Equity	$298K-12.9%	$250K-36.0%	$325K-21.6%	$376K-4.4%	$342K-21.5%	$392K-10.7%	$415K-8.6%	$394K-0.1%
Retained Earnings	-$48.6M-0.8%	-$48.5M-0.8%	-$48.4M-0.8%	-$48.3M-0.8%	-$48.2M-0.8%	-$48.1M-0.8%	-$48.0M-0.8%	-$48.0M-0.8%

Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.

PKTX Cash Flow Statement

PKTX quarterly cash flow statement

Metric	FY2510-K	FY2410-K	FY2310-K	FY2210-K	FY2110-K	FY2010-K	FY1910-K	FY1810-K	FY1710-K	FY1610-K	FY1510-K	FY1410-K	FY1310-K	FY1210-K	FY1110-K
Operating Cash Flow	-$135K+39.3%	-$223K+40.7%	-$376K+53.3%	-$805K+9.6%	-$890K-1.0%	-$881K-3.6%	-$851K-87.6%	-$453K+25.1%	-$605K+26.2%	-$820K-42.8%	-$574K	N/A	-$105K	N/A	N/A
Depreciation & Amortization	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	$0	$0	$0
Stock-Based Compensation	$0-100.0%	$5K	$0-100.0%	$1.1M-24.2%	$1.4M-79.0%	$6.7M+98.5%	$3.4M+423.3%	$649K-28.7%	$910K+19.8%	$760K+43.0%	$531K+107.2%	$257K	N/A	N/A	N/A
Investing Cash Flow	-$56K+3.0%	-$58K+1.9%	-$59K+55.2%	-$132K-45.1%	-$91K-29.6%	-$70K-180.5%	-$25K+29.4%	-$35K-162.2%	$57K+291.4%	-$30K+36.3%	-$47K	N/A	$25K	$0	$0
Financing Cash Flow	$198K-22.9%	$256K-40.5%	$430K-52.5%	$905K+7.1%	$845K+10.1%	$768K-31.3%	$1.1M+246.9%	$322K-32.9%	$480K-43.5%	$850K-14.3%	$992K	N/A	$81K	N/A	N/A

Metric	Q4'2510-K	Q3'2510-Q	Q2'2510-Q	Q1'2510-Q	Q4'2410-K	Q3'2410-Q	Q2'2410-Q	Q1'2410-Q
Operating Cash Flow	$558+101.2%	-$4K+90.0%	-$80K+1.0%	-$52K+10.1%	-$45K+41.6%	-$39K+44.0%	-$81K+43.8%	-$58K+31.8%
Stock-Based Compensation	N/A	$0-100.0%	N/A	N/A	N/A	$1K	N/A	N/A
Investing Cash Flow	-$20K-289.6%	-$6K+67.8%	-$5K+81.4%	-$26K-165.6%	-$5K+79.0%	-$17K-1178.9%	-$26K-32.0%	-$10K+29.2%
Financing Cash Flow	$20K-50.0%	$10K-83.3%	$36K-66.5%	$132K+164.0%	$40K-63.6%	$60K-7.7%	$106K-39.4%	$50K-37.5%

Not reported in any period shown, so not listed: Depreciation & Amortization, Capital Expenditures, Free Cash Flow, Dividends Paid, Share Buybacks.

PKTX Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

PKTX quarterly financial ratios

Metric	FY2510-K	FY2410-K	FY2310-K	FY2210-K	FY2110-K	FY2010-K	FY1910-K	FY1810-K	FY1710-K	FY1610-K	FY1510-K	FY1410-K	FY1310-K	FY1210-K	FY1110-K
Return on Equity	-132.1%-25.7pp	-106.5%-11.1pp	-95.3%+357.4pp	-452.7%	N/A	N/A	N/A	-494.5%-89.4pp	-405.1%-98.3pp	-306.9%+3.4pp	-310.3%	N/A	N/A	N/A	N/A
Return on Assets	-81.4%-3.3pp	-78.1%+8.3pp	-86.5%+325.6pp	-412.1%	N/A	N/A	N/A	-374.4%-82.3pp	-292.1%-10.9pp	-281.3%-2.2pp	-279.0%	N/A	N/A	N/A	N/A
Current Ratio	N/A	N/A	0.48-0.2x	0.64-0.3x	0.90-3.4x	4.33	N/A	1.74-0.8x	2.53-7.2x	9.75+1.4x	8.36	N/A	N/A	N/A	N/A
Debt-to-Equity	0.62+0.3x	0.36+0.3x	0.100.0x	0.10-0.2x	0.26+0.2x	0.11+0.1x	0.05-0.3x	0.32-0.1x	0.39+0.3x	0.090.0x	0.11	N/A	N/A	N/A	N/A
Asset Turnover	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	0.000.0x	0.000.0x	0.000.0x	0.00

Metric	Q4'2510-K	Q3'2510-Q	Q2'2510-Q	Q1'2510-Q	Q4'2410-K	Q3'2410-Q	Q2'2410-Q	Q1'2410-Q
Return on Equity	N/A	-33.9%-12.3pp	-28.0%-7.5pp	-25.9%-2.6pp	N/A	-21.6%-3.3pp	-20.5%+5.0pp	-23.4%+3.8pp
Return on Assets	N/A	-17.8%-0.1pp	-19.2%-1.2pp	-18.5%+1.5pp	N/A	-17.6%+0.2pp	-18.0%+6.8pp	-19.9%+4.0pp
Current Ratio	N/A	N/A	N/A	N/A	N/A	0.08-1.0x	0.06-1.4x	0.06-0.1x
Debt-to-Equity	0.62+0.3x	0.91+0.7x	0.46+0.3x	0.40+0.2x	0.36+0.3x	0.22+0.2x	0.14+0.1x	0.170.0x

Not reported in any period shown, so not listed: Gross Margin, Operating Margin, Net Margin, Asset Turnover, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company	Fiscal year	Revenue	Net income	Net margin	Market cap	Health score
PROTOKINETIX INC PKTX	FY2025	N/A	-$394K	N/A	$82K	—
AVENUE THERAPEUTICS INC ATXI	FY2025	$1.4M	-$2.9M	N/A	$2.8M	—
MOSAIC IMMUNOENGINEERING CPMV	FY2025	N/A	N/A	N/A	$442K	—

Where PROTOKINETIX INC Ranks

Frequently Asked Questions

Is PROTOKINETIX INC profitable?

No, PROTOKINETIX INC (PKTX) reported a net income of -$394K in fiscal year 2025.

What is PROTOKINETIX INC's return on equity (ROE)?

PROTOKINETIX INC (PKTX) has a return on equity of -132.1% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

What is PROTOKINETIX INC's operating cash flow?

PROTOKINETIX INC (PKTX) recorded an outflow of $135K in operating cash flow during fiscal year 2025, representing cash used by core business activities.

What are PROTOKINETIX INC's total assets?

PROTOKINETIX INC (PKTX) had $483K in total assets as of fiscal year 2025, including both current and long-term assets.

How much does PROTOKINETIX INC spend on research and development?

PROTOKINETIX INC (PKTX) invested $107K in research and development during fiscal year 2025.

How many shares does PROTOKINETIX INC have outstanding?

PROTOKINETIX INC (PKTX) had 407M shares outstanding as of fiscal year 2025.

What is PROTOKINETIX INC's debt-to-equity ratio?

PROTOKINETIX INC (PKTX) had a debt-to-equity ratio of 0.62 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

What is PROTOKINETIX INC's return on assets (ROA)?

PROTOKINETIX INC (PKTX) had a return on assets of -81.4% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

What is PROTOKINETIX INC's P/E ratio?

PROTOKINETIX INC (PKTX) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (FY2025). The market capitalization is $82K as of Sep 4, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

What is PROTOKINETIX INC's price-to-sales ratio?

PROTOKINETIX INC (PKTX) has no price-to-sales ratio at the moment: no revenue reported. The market capitalization is $82K as of Sep 4, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

How does PROTOKINETIX INC's liquidity compare with its operating cash outflow?

At the end of fiscal year 2025, PROTOKINETIX INC (PKTX) held $1K in cash, cash equivalents and investments, and reported an operating cash outflow of $135K over that year. Dividing the one by the other, the reported balance equals about 0 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

What is PROTOKINETIX INC's Piotroski F-Score?

PROTOKINETIX INC (PKTX) has a Piotroski F-Score of 1 out of 5 computable signals; 4 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Are PROTOKINETIX INC's earnings high quality?

PROTOKINETIX INC (PKTX) reported a net loss of $394K while operations used $135K of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.