This page shows Synlogic (SYBX) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 13 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).
Financial Health Signals
Based on FY2025 annual data. Scores normalized against common benchmarks. How we calculate these scores
Synlogic's revenue declined 100% year-over-year, from $8K to $0. This contraction results in a growth score of 0/100.
Synlogic carries a low D/E ratio of 0.30, meaning only $0.30 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 96/100, indicating a strong balance sheet with room for future borrowing.
With a current ratio of 4.30, Synlogic holds $4.30 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 85/100.
Synlogic generates a -8.5% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100. This is up from -183.2% the prior year.
Synlogic passes 2 of 9 financial strength tests. 1 of 4 profitability signals pass, 1 of 3 leverage/liquidity signals pass, neither operating efficiency signal passes.
For every $1 of reported earnings, Synlogic generates $4.34 in operating cash flow (-$4.4M OCF vs -$1.0M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.
Key Financial Metrics
Earnings & Revenue
Synlogic generated $0 in revenue in fiscal year 2025. This represents a decrease of 100.0% from the prior year.
Synlogic's EBITDA was -$4.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 90.1% from the prior year.
Synlogic reported -$1.0M in net income in fiscal year 2025. This represents an increase of 95.7% from the prior year.
Synlogic earned $-0.08 per diluted share (EPS) in fiscal year 2025. This represents an increase of 95.8% from the prior year.
Cash & Balance Sheet
Synlogic generated -$4.4M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 86.2% from the prior year.
Synlogic held $14.7M in cash against $0 in long-term debt as of fiscal year 2025.
Synlogic had 12M shares outstanding in fiscal year 2025. This represents an increase of 0.0% from the prior year.
Margins & Returns
Synlogic's ROE was -8.5% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 174.7 percentage points from the prior year.
Capital Allocation
Synlogic invested $43K in research and development in fiscal year 2025. This represents a decrease of 99.5% from the prior year.
Synlogic invested $0 in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 100.0% from the prior year.
SYBX Income Statement
| Metric | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 |
|---|---|---|---|---|---|---|---|---|
| Revenue | N/A | $0 | $0 | $0 | N/A | $0 | $0-100.0% | $8K |
| Cost of Revenue | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Gross Profit | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| R&D Expenses | N/A | N/A | N/A | $22K | N/A | N/A | $2.2M-71.4% | $7.7M |
| SG&A Expenses | N/A | $818K+2.3% | $800K-4.3% | $836K | N/A | $1.2M-1.2% | $1.2M-59.1% | $2.9M |
| Operating Income | N/A | -$991K-27.5% | -$777K+13.5% | -$898K | N/A | -$748K-278.5% | $419K+101.1% | -$38.8M |
| Interest Expense | N/A | N/A | N/A | N/A | N/A | $0 | $0 | $0 |
| Income Tax | N/A | $0 | $0 | N/A | N/A | $0-100.0% | $5K | N/A |
| Net Income | N/A | -$2.3M-335.0% | -$529K-266.9% | $317K | N/A | -$117K-103.8% | $3.1M+112.0% | -$25.6M |
| EPS (Diluted) | N/A | $-0.19-375.0% | $-0.04-233.3% | $0.03 | N/A | $-0.01-104.0% | $0.25+111.8% | $-2.11 |
SYBX Balance Sheet
| Metric | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 |
|---|---|---|---|---|---|---|---|---|
| Total Assets | $15.4M-6.7% | $16.6M-4.7% | $17.4M-3.3% | $18.0M-9.4% | $19.8M-4.5% | $20.8M-4.1% | $21.6M-40.0% | $36.1M |
| Current Assets | $15.4M-6.7% | $16.5M-4.7% | $17.3M-3.3% | $17.9M-9.4% | $19.8M-4.5% | $20.7M-4.0% | $21.6M-38.3% | $34.9M |
| Cash & Equivalents | $14.7M-5.9% | $15.6M-8.4% | $17.0M-1.4% | $17.3M-8.4% | $18.9M-2.7% | $19.4M-2.9% | $20.0M-19.6% | $24.8M |
| Inventory | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Accounts Receivable | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Goodwill | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Total Liabilities | $3.6M-42.5% | $6.2M+30.4% | $4.8M-2.0% | $4.9M-31.1% | $7.1M-7.5% | $7.6M-10.2% | $8.5M-68.1% | $26.7M |
| Current Liabilities | $3.6M-42.5% | $6.2M+30.4% | $4.8M-2.0% | $4.9M-31.1% | $7.1M-7.5% | $7.6M-10.2% | $8.5M-42.7% | $14.9M |
| Long-Term Debt | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Total Equity | $11.9M+14.9% | $10.3M-18.0% | $12.6M-3.8% | $13.1M+2.7% | $12.8M-2.7% | $13.1M-0.1% | $13.1M+39.6% | $9.4M |
| Retained Earnings | -$442.7M+0.3% | -$444.2M-0.5% | -$441.9M-0.1% | -$441.3M+0.1% | -$441.7M-0.2% | -$440.9M0.0% | -$440.8M+0.7% | -$443.9M |
SYBX Cash Flow Statement
| Metric | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 |
|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | -$923K+35.7% | -$1.4M-259.9% | -$399K+75.1% | -$1.6M-181.9% | -$568K+12.3% | -$648K+95.7% | -$15.0M+2.8% | -$15.4M |
| Capital Expenditures | $0 | $0 | $0 | $0 | $0 | $0+100.0% | -$381K-196.5% | $395K |
| Free Cash Flow | -$923K+35.7% | -$1.4M-259.9% | -$399K+75.1% | -$1.6M-181.9% | -$568K+12.3% | -$648K+95.8% | -$15.4M+2.8% | -$15.8M |
| Investing Cash Flow | $0 | $0-100.0% | $155K+1191.7% | $12K-60.0% | $30K-58.3% | $72K-99.2% | $9.0M-45.0% | $16.3M |
| Financing Cash Flow | $0 | $0 | $0 | $0-100.0% | $9K+1000.0% | -$1K-100.7% | $148K+825.0% | $16K |
| Dividends Paid | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Share Buybacks | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
SYBX Financial Ratios
| Metric | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 |
|---|---|---|---|---|---|---|---|---|
| Gross Margin | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Operating Margin | N/A | N/A | N/A | N/A | N/A | N/A | N/A | -485562.5% |
| Net Margin | N/A | N/A | N/A | N/A | N/A | N/A | N/A | -320075.0% |
| Return on Equity | N/A | -22.3%-18.1pp | -4.2%-6.6pp | 2.4% | N/A | -0.9%-24.3pp | 23.4%+295.9pp | -272.4% |
| Return on Assets | N/A | -13.9%-10.9pp | -3.0%-4.8pp | 1.8% | N/A | -0.6%-14.8pp | 14.2%+85.3pp | -71.0% |
| Current Ratio | 4.30+1.6 | 2.65-1.0 | 3.63-0.1 | 3.68+0.9 | 2.80+0.1 | 2.71+0.2 | 2.53+0.2 | 2.35 |
| Debt-to-Equity | 0.30-0.3 | 0.60+0.2 | 0.380.0 | 0.37-0.2 | 0.55-0.0 | 0.58-0.1 | 0.65-2.2 | 2.84 |
| FCF Margin | N/A | N/A | N/A | N/A | N/A | N/A | N/A | -197887.5% |
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Frequently Asked Questions
What is Synlogic's annual revenue?
Synlogic (SYBX) reported $0 in total revenue for fiscal year 2025. This represents a -100.0% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.
How fast is Synlogic's revenue growing?
Synlogic (SYBX) revenue declined by 100% year-over-year, from $8K to $0 in fiscal year 2025.
Is Synlogic profitable?
No, Synlogic (SYBX) reported a net income of -$1.0M in fiscal year 2025.
What is Synlogic's EBITDA?
Synlogic (SYBX) had EBITDA of -$4.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.
What is Synlogic's return on equity (ROE)?
Synlogic (SYBX) has a return on equity of -8.5% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.
What is Synlogic's free cash flow?
Synlogic (SYBX) generated -$4.4M in free cash flow during fiscal year 2025. This represents a 86.2% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.
What is Synlogic's operating cash flow?
Synlogic (SYBX) generated -$4.4M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.
What are Synlogic's total assets?
Synlogic (SYBX) had $15.4M in total assets as of fiscal year 2025, including both current and long-term assets.
What are Synlogic's capital expenditures?
Synlogic (SYBX) invested $0 in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.
How much does Synlogic spend on research and development?
Synlogic (SYBX) invested $43K in research and development during fiscal year 2025.
What is Synlogic's current ratio?
Synlogic (SYBX) had a current ratio of 4.30 as of fiscal year 2025, which is generally considered healthy.
What is Synlogic's debt-to-equity ratio?
Synlogic (SYBX) had a debt-to-equity ratio of 0.30 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.
What is Synlogic's return on assets (ROA)?
Synlogic (SYBX) had a return on assets of -6.5% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.
What is Synlogic's cash runway?
Based on fiscal year 2025 data, Synlogic (SYBX) had $14.7M in cash against an annual operating cash burn of $4.4M. This gives an estimated cash runway of approximately 40 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.
What is Synlogic's Piotroski F-Score?
Synlogic (SYBX) has a Piotroski F-Score of 2 out of 9, indicating weak financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.
Are Synlogic's earnings high quality?
Synlogic (SYBX) has an earnings quality ratio of 4.34x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.
How financially healthy is Synlogic?
Synlogic (SYBX) scores 45 out of 100 on our Financial Profile, indicating moderate overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.