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AC Immune Announces Upcoming Industry Symposium on Parkinson’s Disease and Presentation at AD/PD™ 2026

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AC Immune (NASDAQ: ACIU) will host an industry symposium on Parkinson’s disease and present a first-in-class TDP-43 PET-tracer at AD/PD™ 2026 in Copenhagen, March 17–21, 2026. The symposium on March 18 highlights a precision prevention approach and features data updates, scientific talks, and a Q&A session.

Oral presentation of [18F]ACI-19626 is scheduled for March 19, focusing on biomarker pathways linking amyloid, tau, and neurodegeneration. A symposium replay will be available on the company events page.

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News Market Reaction – ACIU

-3.87%
3 alerts
-3.87% Session close to close
-2.2% Trough Tracked
$272.11M Market Cap
0.3x Rel. Volume

In the Mar 5 session, ACIU declined 3.87%, reflecting a moderate negative market reaction. Argus tracked a trough of -2.2% from its starting point during tracking. Our momentum scanner triggered 3 alerts that day, indicating moderate trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement highlights AC Immune’s scientific visibility at AD/PD™ 2026 and its focus on Parki...
Analysis

This announcement highlights AC Immune’s scientific visibility at AD/PD™ 2026 and its focus on Parkinson’s disease, including a first-in-class TDP-43 PET tracer and the Phase 2 VacSYn program. Prior updates showed cash resources of CHF 108.5M and funding into Q3 2027. Investors may track clinical readouts across Parkinson’s and NLRP3 programs, as well as how these data support the company’s precision prevention strategy in neurodegeneration.

Key Figures

Share price: $2.825 Daily change: -2.41% 52-week range: $1.4299–$4.00 +5 more
8 metrics
Share price $2.825 Pre-news close for ACIU
Daily change -2.41% Price change over prior 24 hours
52-week range $1.4299–$4.00 Current price 29.37% below 52-week high
Cash resources CHF 108.5M As of Sept 30, 2025 (Q3 2025 results)
Cash runway to end of Q3 2027 Funding guidance excluding milestone income
Workforce reduction ≈30% Restructuring to focus on key R&D assets
VacSYn Part 1 size 34 patients Phase 2 ACI-7104.056 early Parkinson’s trial
Responder rate 100% Immunogenicity targets met in VacSYn Part 1

Historical Context

5 past events · Latest: Feb 24 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Feb 24 Phase 1 trial start Positive +7.5% First participant dosed in Phase 1 ACI-19764 NLRP3 inhibitor trial.
Dec 11 Phase 2 interim data Positive +15.4% Positive interim Phase 2 VacSYn data in early Parkinson’s disease.
Nov 11 Investor conference Neutral +1.2% Participation and fireside chat at Jefferies 2025 London conference.
Nov 04 Earnings and update Neutral +3.8% Q3 2025 results, cash runway to Q3 2027, and narrowed R&D focus.
Oct 28 Advisory appointment Positive -1.9% Appointment of Prof. Catherine Mummery as Clinical Advisory Board Chair.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent substantive R&D and clinical updates have generally aligned with positive price reactions, with only one notable divergence on a management appointment.

Recent Company History

Over the past six months, AC Immune has highlighted several pipeline and corporate milestones. Positive interim Phase 2 VacSYn data for Parkinson’s disease and a new Phase 1 NLRP3 trial both saw share gains of 15.41% and 7.51%, respectively. Q3 2025 results emphasized CHF 108.5M in cash and funding into Q3 2027. A Jefferies conference appearance had a modest positive reaction, while the appointment of Catherine Mummery to chair the Clinical Advisory Board saw a small negative move despite its strategic significance.

Key Terms

phase 2, pet-tracer, tdp-43, biomarker, +3 more
7 terms
phase 2 medical
"Stabilizing the progression of Parkinson’s disease with active immunotherapy: Interim results of the Phase 2 VacSYn trial of ACI-7104.056"
Phase 2 is the mid-stage clinical trial where a new drug or treatment is tested in a larger group of patients to see if it works and to keep checking safety after initial human testing. Think of it as a field test that proves whether a product actually delivers its promised benefit. Investors watch Phase 2 closely because its results strongly influence a medicine’s chances of reaching the market, the size of its potential sales, and the company’s valuation.
pet-tracer medical
"showcases potential of first-in-class TDP-43 PET-tracer ACI-19626"
A pet-tracer is a tiny, short-lived radioactive molecule used in positron emission tomography (PET) scans to highlight biological processes inside the body, similar to how a dye makes plumbing leaks visible on an inspection camera. For investors, pet-tracers matter because they are the core diagnostic tools that drive demand for imaging services, influence reimbursement and regulatory approvals, and can represent recurring revenue and growth potential for companies that develop, manufacture, or distribute them.
tdp-43 medical
"Discovery and initial clinical evaluation of [18f]ACI-19626, a first-in-class TDP-43 PET-tracer"
TDP-43 is a protein inside cells that helps regulate how genetic instructions are used; when it misfolds or accumulates into clumps in brain or spinal cord cells, it is linked to neurodegenerative conditions like ALS and some dementias. For investors, TDP-43 matters because it is a clear biological target for diagnostics and therapies—detecting or stopping its abnormal behavior could change patient care and create commercial value, similar to fixing a faulty part in a complex machine.
biomarker medical
"Misfolding of α-synuclein as fluid biomarker measured with the iRS platform of betaSENSE"
A biomarker is a measurable indicator found in the body, such as in blood or tissues, that provides information about health, disease, or how the body responds to treatment. For investors, biomarkers can signal the potential success or risk of medical products or therapies, influencing the value of related companies and industry trends. They act like signals or clues that help assess the progress of medical advancements and their market impact.
α-synuclein medical
"Targeting α-synuclein in Parkinson’s disease: pathophysiology and supporting evidence"
A-synuclein is a small protein found in brain cells that can misfold and stick together, forming clumps that harm neurons—think of it like lint building up in a filter and blocking normal function. It matters to investors because these clumps are central to diseases such as Parkinson’s and related dementias, making a-synuclein a major focus for drug development and diagnostic tests; success or failure of therapies or tests targeting it can drive biotech valuations and regulatory decisions.
active immunotherapy medical
"Stabilizing the progression of Parkinson’s disease with active immunotherapy: Interim results of the Phase 2 VacSYn trial"
Active immunotherapy is a medical approach that trains a patient’s own immune system to recognize and attack disease, often by exposing it to a target that mimics the threat. Think of it like coaching the body's guard dogs to spot a specific intruder; for investors it matters because successful therapies can create durable, high-value treatments but also carry high clinical and regulatory risk and long development timelines.
form 144 regulatory
"submitted a Form 144 notifying the proposed sale of 45,000 common shares"
Form 144 is a document that investors must file with the government when they plan to sell a large number of shares of a company's stock. It helps ensure transparency so everyone knows how many shares are being sold and when, which can impact the stock's price.
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AC Immune Announces Upcoming Industry Symposium on Parkinson’s Disease and Presentation at AD/PD™ 2026

  • AC Immune to host symposium highlighting Precision Prevention approach to Parkinson's disease
  • Presentation at International Conference on Alzheimer’s and Parkinson’s Disease (AD/PD™ 2026) showcases potential of first-in-class TDP-43 PET-tracer ACI-19626

Lausanne, Switzerland, March 5, 2026 -- AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision therapeutics for neurodegenerative diseases, today announced it will host an industry symposium on how a precision prevention approach to Parkinson’s disease may now be within reach, based on lessons from Alzheimer’s disease.

AC Immune will also present its first-in-class TDP-43 PET-tracer on ACI-19626 at the International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD™ 2026) taking place in Copenhagen, Denmark, on March 17-21, 2026.

Industry Symposium: From Treatment to Prevention in Parkinson’s Disease

Session Date/Time: Wednesday, March 18, 2026, 8:40 – 10:40 am CET
Location: Hall A1

  • Opening and Closing Remarks: Andrea Pfeifer, Ph.D., CEO of AC Immune
  • Shifting treatment to prevention: lessons learned from Alzheimer’s disease

Presenter: Prof. Catherine Mummery (University College London)
Time: 8:45 – 9:00 am CET

  • Targeting α-synuclein in Parkinson’s disease: pathophysiology and supporting evidence

Presenter: Werner Poewe, M.D. (Medical University of Innsbruck)
Time: 9:00 – 9:25 am CET

  • Misfolding of α-synuclein as fluid biomarker measured with the iRS platform of betaSENSE

Presenter: Prof. Klaus Gerwert (Centre for Protein Diagnostics at Ruhr University Bochum)
Time: 9:25 – 9:40 am CET

  • Stabilizing the progression of Parkinson’s disease with active immunotherapy: Interim results of the Phase 2 VacSYn trial of ACI-7104.056

Presenter: Günther Staffler, Ph.D. (AC Immune)
Time: 9:40 – 10:05 am CET

  • Intracellular targeting of α-synuclein with Morphomer small molecules

Presenter: Francesca Capotosti, Ph.D. (AC Immune)
Time: 10:05 – 10:20 am CET

The presentations will be followed by a Q&A session, and a replay of the Industry Symposium will be available on the Events page of AC Immune’s website after the event.

Oral Presentation

  • Discovery and initial clinical evaluation of [18f]ACI-19626, a first-in-class TDP-43 PET-tracer

Presenter: Tamara Seredenina, Ph.D. (AC Immune)
Session: Biomarker Pathways Linking Amyloid, Tau, and Neurodegeneration
Location: Hall 180-181
Date/Time: Thursday, March 19, 2026 at 4:50 – 5:05 pm CET

About AC Immune SA 

AC Immune SA is a clinical-stage biopharmaceutical company and a global leader in precision prevention for neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and NeuroOrphan indications driven by misfolded proteins. The Company’s two clinically validated technology platforms, SupraAntigen® and Morphomer®, fuel its pipeline of first- and best-in-class assets, which currently features a range of therapeutic and diagnostic programs, including candidates in Phase 2 and Phase 3 development. AC Immune has a strong track record of securing strategic partnerships with leading global pharmaceutical companies, resulting in substantial non-dilutive funding to advance its proprietary programs and >$4.5 billion in potential milestone payments plus royalties.

SupraAntigen® is a registered trademark of AC Immune SA in the following territories: AU, EU, CH, GB, JP, RU, SG and USA. Morphomer® is a registered trademark of AC Immune SA in CA, CN, CH, EU, GB, JP, KR, NO, RU and SG.

The information on our website and any other websites referenced herein is expressly not incorporated by reference into, and does not constitute a part of, this press release.

For further information, please contact:

SVP, Investor Relations & Corporate Communications

Gary Waanders, Ph.D., MBA
AC Immune
Phone: +41 21 345 91 91
Email: gary.waanders@acimmune.com





 
International Media

Chris Maggos
Cohesion Bureau
Phone: +41 79 367 6254
Email: chris.maggos@cohesionbureau.com
 

Forward looking statements

This press release contains statements that constitute “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements are statements other than historical fact and may include statements that address future operating, financial or business performance or AC Immune’s strategies or expectations. In some cases, you can identify these statements by forward-looking words such as “may,” “might,” “will,” “should,” “expects,” “plans,” “anticipates,” “believes,” “estimates,” “predicts,” “projects,” “potential,” “outlook” or “continue,” and other comparable terminology. Forward-looking statements are based on management’s current expectations and beliefs and involve significant risks and uncertainties that could cause actual results, developments and business decisions to differ materially from those contemplated by these statements. These risks and uncertainties include those described under the captions “Item 3. Key Information – Risk Factors” and “Item 5. Operating and Financial Review and Prospects” in AC Immune’s Annual Report on Form 20-F and other filings with the Securities and Exchange Commission. Forward-looking statements speak only as of the date they are made, and AC Immune does not undertake any obligation to update them in light of new information, future developments or otherwise, except as may be required under applicable law. All forward-looking statements are qualified in their entirety by this cautionary statement.

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FAQ

What is AC Immune presenting at AD/PD 2026 (NASDAQ: ACIU) and when?

AC Immune will present the first-in-class TDP-43 PET-tracer [18F]ACI-19626 on March 19, 2026 at 4:50 pm CET. According to AC Immune, the oral presentation appears in the Biomarker Pathways session linking amyloid, tau, and neurodegeneration.

When is the AC Immune industry symposium on Parkinson’s disease at AD/PD 2026?

The AC Immune symposium takes place Wednesday, March 18, 2026 from 8:40–10:40 am CET in Hall A1. According to AC Immune, it covers precision prevention, α-synuclein biology, biomarkers, immunotherapy interim results, and a Q&A session.

What topics and speakers will AC Immune feature at the March 18 symposium (ACIU)?

Speakers include Andrea Pfeifer, Prof. Catherine Mummery, Werner Poewe, Prof. Klaus Gerwert, and AC Immune scientists presenting on α-synuclein, biomarkers, and interim VacSYn Phase 2 results. According to AC Immune, talks run from 8:45–10:20 am CET.

Will AC Immune make interim clinical data available at AD/PD 2026 for ACI-7104 (NASDAQ: ACIU)?

Yes, AC Immune will present interim Phase 2 VacSYn results for ACI-7104 during the symposium on March 18, 2026. According to AC Immune, the presentation covers active immunotherapy and its impact on disease progression stabilization.

How can investors access the AC Immune symposium content after AD/PD 2026 (ACIU)?

A replay of the industry symposium will be available on AC Immune's Events page after the conference. According to AC Immune, the replay follows the live March 18 session and includes presentations and the Q&A segment.