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Altimmune Announces Multiple Presentations at Upcoming American Diabetes Association’s Scientific Sessions

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Altimmune (NASDAQ: ALT) announced four presentations on pemvidutide, their investigational GLP-1/glucagon dual receptor agonist, at the upcoming American Diabetes Association's 85th Scientific Sessions in Chicago. The presentations include one oral presentation focusing on pemvidutide's effects on cardioinflammatory lipids in subjects with obesity, and three poster presentations covering cardiovascular safety, central adiposity measurements, and cholesterol transport studies. Pemvidutide is being developed for multiple indications including MASH, obesity, alcohol use disorder, and alcohol-associated liver disease. The presentations will take place between June 20-23, 2025, featuring research from Altimmune's senior directors Dr. John J. Suschak and Dr. Shaheen Tomah.
Altimmune (NASDAQ: ALT) ha annunciato quattro presentazioni su pemvidutide, il loro agonista duale dei recettori GLP-1/glucagone in fase di studio, durante le prossime 85esime Sessioni Scientifiche dell'American Diabetes Association a Chicago. Le presentazioni includono un intervento orale che si concentra sugli effetti di pemvidutide sui lipidi cardioinfiammatori in soggetti con obesità, e tre presentazioni poster che trattano la sicurezza cardiovascolare, le misurazioni dell'adiposità centrale e gli studi sul trasporto del colesterolo. Pemvidutide è in sviluppo per diverse indicazioni, tra cui MASH, obesità, disturbo da uso di alcol e malattia epatica associata all'alcol. Le presentazioni si terranno dal 20 al 23 giugno 2025 e presenteranno ricerche dei direttori senior di Altimmune, il dott. John J. Suschak e il dott. Shaheen Tomah.
Altimmune (NASDAQ: ALT) anunció cuatro presentaciones sobre pemvidutide, su agonista dual de receptores GLP-1/glucagón en investigación, en las próximas 85ª Sesiones Científicas de la American Diabetes Association en Chicago. Las presentaciones incluyen una exposición oral centrada en los efectos de pemvidutide sobre los lípidos cardioinflamatorios en sujetos con obesidad, y tres presentaciones en formato póster que abordan la seguridad cardiovascular, las mediciones de adiposidad central y los estudios sobre el transporte de colesterol. Pemvidutide se está desarrollando para múltiples indicaciones, incluyendo MASH, obesidad, trastorno por consumo de alcohol y enfermedad hepática asociada al alcohol. Las presentaciones se realizarán entre el 20 y el 23 de junio de 2025, con investigaciones de los directores senior de Altimmune, el Dr. John J. Suschak y el Dr. Shaheen Tomah.
Altimmune(NASDAQ: ALT)는 시카고에서 열리는 제85회 미국 당뇨병 협회(ADA) 과학 세션에서 그들의 연구 중인 GLP-1/글루카곤 이중 수용체 작용제인 펨비두타이드에 관한 네 건의 발표를 발표했습니다. 발표에는 비만 환자에서 펨비두타이드가 심혈관 염증성 지질에 미치는 영향을 다루는 구두 발표 한 건과 심혈관 안전성, 중심 비만 측정, 콜레스테롤 수송 연구를 다루는 세 건의 포스터 발표가 포함됩니다. 펨비두타이드는 MASH, 비만, 알코올 사용 장애, 알코올 관련 간 질환 등 다양한 적응증에 대해 개발 중입니다. 발표는 2025년 6월 20일부터 23일까지 진행되며, Altimmune의 수석 이사인 John J. Suschak 박사와 Shaheen Tomah 박사의 연구가 소개됩니다.
Altimmune (NASDAQ : ALT) a annoncé quatre présentations sur le pemvidutide, leur agoniste double récepteur GLP-1/glucagon en cours d'investigation, lors des 85èmes Sessions Scientifiques de l'American Diabetes Association à Chicago. Les présentations comprennent une communication orale portant sur les effets du pemvidutide sur les lipides cardio-inflammatoires chez des sujets obèses, ainsi que trois présentations par affiches traitant de la sécurité cardiovasculaire, des mesures de l'adiposité centrale et des études sur le transport du cholestérol. Le pemvidutide est développé pour plusieurs indications, dont la MASH, l'obésité, le trouble lié à l'usage d'alcool et la maladie hépatique associée à l'alcool. Les présentations auront lieu du 20 au 23 juin 2025 et mettront en avant des recherches des directeurs seniors d'Altimmune, le Dr John J. Suschak et le Dr Shaheen Tomah.
Altimmune (NASDAQ: ALT) kündigte vier Präsentationen zu Pemvidutid, ihrem untersuchten GLP-1/Glukagon-Dualrezeptor-Agonisten, auf der bevorstehenden 85. Wissenschaftlichen Sitzung der American Diabetes Association in Chicago an. Die Präsentationen umfassen eine mündliche Präsentation, die sich auf die Auswirkungen von Pemvidutid auf cardioinflammatorische Lipide bei adipösen Probanden konzentriert, sowie drei Posterpräsentationen zu kardiovaskulärer Sicherheit, Messungen der zentralen Adipositas und Cholesterintransportstudien. Pemvidutid wird für mehrere Indikationen entwickelt, darunter MASH, Adipositas, Alkoholgebrauchsstörung und alkoholbedingte Lebererkrankungen. Die Präsentationen finden vom 20. bis 23. Juni 2025 statt und zeigen Forschungen der Senior Directors von Altimmune, Dr. John J. Suschak und Dr. Shaheen Tomah.
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GAITHERSBURG, Md., June 13, 2025 (GLOBE NEWSWIRE) -- Altimmune, Inc. (Nasdaq: ALT), a late clinical-stage biopharmaceutical company developing novel peptide-based therapeutics for liver and cardiometabolic diseases, today announced an oral presentation and three poster presentations on pemvidutide at the American Diabetes Association’s (ADA) 85th Scientific Sessions, to be held in Chicago, IL from June 20-23, 2025. Pemvidutide is a novel, investigational GLP-1/glucagon dual receptor agonist under development for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), obesity, alcohol use disorder (AUD) and alcohol-associated liver disease (ALD).

Details for the oral presentation are as follows:

Session Title:Early Phase, Post Hoc, and Subgroup Analyses from Clinical Trials Testing Incretin-Based Therapies – Take 1
Session Date/Time:Saturday, June 21, 2025, 4:30 PM - 6:00 PM CDT
Presentation Title:Effects of Pemvidutide, a GLP-1/Glucagon Dual Receptor Agonist, on Cardioinflammatory Lipids in Subjects with Obesity or Overweight
Presenter:John J. Suschak, Ph.D., Senior Director, Translational Science, Altimmune
Presentation Date/Time:Saturday, June 21, 2025 at 5:45 PM CDT


Details of the poster presentations are as follows:

Title:Integrated Analysis Supports Cardiovascular Safety and Risk Reduction with Pemvidutide Treatment (poster #749-P)
Presenter:Shaheen Tomah, M.D., Director, Clinical Development, Altimmune
Presentation Date/Time:Sunday, June 22, 2025, 12:30 PM - 1:30 PM CDT


Title:Non-invasive Tests of Central Adiposity Correlate with Reductions in MRI-measured Visceral Adipose Tissue Mass in Subjects with Overweight or Obesity Treated with Pemvidutide (poster #748-P)
Presenter:Shaheen Tomah, M.D., Director, Clinical Development, Altimmune
Presentation Date/Time:Sunday, June 22, 2025, 12:30 PM - 1:30 PM CDT


Title:Pemvidutide, a Balanced GLP-1/Glucagon Dual Receptor Agonist, Enhances Reverse Cholesterol Transport in a Golden Syrian Hamster Model (poster #778-P)
Presenter:John J. Suschak, Ph.D., Senior Director, Translational Science, Altimmune
Presentation Date/Time:Sunday, June 22, 2025, 12:30PM - 1:30 PM CDT


These presentations will be accessible on the Events section of the Altimmune website.

About Pemvidutide
Pemvidutide is a novel, investigational, peptide-based 1:1 GLP-1/glucagon dual receptor agonist in development for the treatment of MASH, obesity, alcohol use disorder (AUD) and alcohol-associated liver disease (ALD). Activation of the GLP-1 and glucagon receptors is believed to mimic the complementary effects of diet and exercise on weight loss, with GLP-1 suppressing appetite and glucagon increasing energy expenditure. Glucagon is also recognized as having direct effects on hepatic fat metabolism, which is believed to lead to rapid reductions in levels of liver fat and serum lipids. In clinical trials to date, once-weekly pemvidutide has demonstrated compelling weight loss with class-leading lean mass preservation, and robust reductions in triglycerides, LDL cholesterol, liver fat content and blood pressure. The U.S. FDA has granted Fast Track designation to pemvidutide for the treatment of MASH. Pemvidutide completed the MOMENTUM Phase 2 obesity trial in 2024 and is being studied in the ongoing IMPACT Phase 2b MASH trial with top line results expected in Q2 2025. IND applications in AUD and ALD have received FDA clearance with the Phase 2 trial in AUD having commenced in Q2 2025 and the ALD trial scheduled to commence in Q3 2025.

About Altimmune
Altimmune is a late clinical-stage biopharmaceutical company focused on developing novel peptide-based therapeutics for liver and cardiometabolic diseases. The Company’s lead program is pemvidutide, a GLP-1/glucagon dual receptor agonist for the treatment of MASH, obesity, alcohol use disorder (AUD) and alcohol-associated liver disease (ALD). For more information, please visit www.altimmune.com.

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Company Contact:
Greg Weaver
Chief Financial Officer
Phone: 240-654-1450
ir@altimmune.com

Investor Contact:
Lee Roth
Burns McClellan
Phone: 646-382-3403
lroth@burnsmc.com

Media Contact:
Jake Robison
Inizio Evoke, Biotech
Phone: 619-849-5383
jake.robison@inizioevoke.com

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FAQ

What is Altimmune's pemvidutide and what conditions is it being developed for?

Pemvidutide is a novel GLP-1/glucagon dual receptor agonist being developed by Altimmune for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), obesity, alcohol use disorder (AUD), and alcohol-associated liver disease (ALD).

When and where will Altimmune (ALT) present their pemvidutide research?

Altimmune will present their pemvidutide research at the American Diabetes Association's 85th Scientific Sessions in Chicago from June 20-23, 2025, featuring one oral presentation and three poster presentations.

What are the main topics of Altimmune's presentations at ADA 2025?

The presentations cover pemvidutide's effects on cardioinflammatory lipids, cardiovascular safety and risk reduction, central adiposity measurements, and reverse cholesterol transport studies.

Who are the key presenters for Altimmune at the ADA Scientific Sessions 2025?

The key presenters are Dr. John J. Suschak, Senior Director of Translational Science, and Dr. Shaheen Tomah, Director of Clinical Development at Altimmune.
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