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Autonomix Medical Secures New U.S. Patent Strengthening Next-Generation Precision Neuromodulation Platform

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Autonomix Medical (NASDAQ: AMIX) announced the issuance of U.S. Patent No. 12,471,776, titled “ANS Assessment Systems, Kits, and Methods,” which broadens protection for its autonomic nervous system (ANS) assessment technologies. The patent covers systems, devices and methods for monitoring physiologic signals to evaluate sympathetic and parasympathetic nervous system activity using multiple assessment techniques.

According to Autonomix, the intellectual property may support patient selection, procedural guidance, treatment feedback and post-treatment monitoring across a wide range of neuromodulation applications. The patented systems use advanced imaging, sensors and algorithms to analyze ANS activity and are aimed at precision-based diagnosis and treatment of diseases involving the peripheral nervous system, further expanding the company’s neuromodulation-focused IP portfolio.

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Market reaction after U.S. patent issuance: AMIX -12.06% in the Jul 23 session

-12.06% 34.0x vol
87 alerts
-12.06% Session close to close
+20.1% Peak Tracked
-32.2% Trough Tracked
$2.33M Market Cap
34.0x Rel. Volume

In the Jul 23 session, AMIX declined 12.06%, reflecting a significant negative market reaction. Argus tracked a peak move of +20.1% during that session. Argus tracked a trough of -32.2% from its starting point during tracking. Our momentum scanner triggered 87 alerts that day, indicating high trading interest and price volatility. Trading volume was exceptionally heavy at 34.0x the daily average, suggesting significant selling pressure.

Data tracked by StockTitan Argus on the day of publication.

Market Context

The stock dropped -12.1% in the session following this news. On July 13, 2026, a prior patent-grant ...
Analysis

The stock dropped -12.1% in the session following this news. On July 13, 2026, a prior patent-grant announcement was associated with a -12.48% 24-hour reaction. The current patent broadens platform coverage, while the active S-3 registers warrant-related resale shares rather than company proceeds.

Key Figures

U.S. Patent Number: 12,471,776
1 metrics
U.S. Patent Number 12,471,776 Newly issued patent titled “ANS Assessment Systems, Kits, and Methods”

Historical Context

5 past events · Latest: Jul 15 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Jul 15 Patent issuance Positive -1.2% U.S. patent expanded the neural sensing and therapeutic platform into urology.
Jul 13 Warrant inducement Negative -9.6% $2.6 million warrant exercise proceeds accompanied by newly issued replacement warrants.
Jul 13 Patent grant Positive -12.5% Canadian patent strengthened global protections for nerve-targeted therapies.
Jun 22 Neural sensing program Positive +3.1% Preclinical evidence showed real-time detection of renal nerve activity changes.
Jun 18 Reverse stock split Neutral +4.3% A 1-for-21 reverse split reduced outstanding shares and changed the trading structure.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent patent announcements showed negative 24-hour reactions, while a standalone neural-sensing program had a positive reaction.

Key Terms

autonomic nervous system, neuromodulation, electrophysiological signals, autonomic dysfunction
4 terms
autonomic nervous system medical
"systems, devices and methods for monitoring physiologic signals to assess autonomic nervous system"
A network of nerves that automatically controls involuntary body functions such as heart rate, blood pressure, digestion and breathing, operating without conscious effort. Like an automatic thermostat that keeps a building’s climate steady, it is a major clinical target: drugs, devices or tests that affect this system can change patient outcomes, regulatory approval prospects and commercial value, so investors watch developments closely.
neuromodulation medical
"across a broad range of neuromodulation applications"
Neuromodulation is the use of devices or targeted treatments to change how nerves or brain circuits send signals, much like adjusting the volume or tuning on an audio system to alter what you hear. For investors, it matters because these therapies can treat chronic conditions (pain, movement disorders, depression) where existing medicines fall short, creating potential markets, regulatory milestones, and durable revenue streams if technologies prove safe and effective.
electrophysiological signals technical
"monitoring physiologic and electrophysiological signals using advanced imaging"
Electrical patterns produced by nerve and muscle cells that can be measured on or inside the body with sensors and electrodes; examples include the heart’s rhythm and the brain’s activity. Like watching the wiring of a house to see which circuits are on or shorting, these signals reveal how tissues are functioning and how they respond to drugs, devices or procedures, so they matter to investors because they drive clinical utility, regulatory data and commercial applications.
autonomic dysfunction medical
"disease states associated with autonomic dysfunction"
A medical condition in which the autonomic nervous system — the body’s automatic control system for heart rate, blood pressure, digestion, temperature and other involuntary functions — does not work properly. Symptoms can include fainting, rapid or slow heart rate, lightheadedness and digestive problems. It matters to investors because it influences demand for diagnostics, drugs, devices and clinical trials, and can affect healthcare costs and regulatory attention for treatments.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Patent Broadens Intellectual Property Protecting Advanced Autonomic Nervous System Assessment Technologies Designed to Enhance Patient Selection, Treatment Precision and Future Clinical Applications

THE WOODLANDS, TX, July 23, 2026 (GLOBE NEWSWIRE) -- Autonomix Medical, Inc. (NASDAQ: AMIX) (“Autonomix” or the “Company”), a medical device company dedicated to advancing precision nerve-targeted treatments, today announced the issuance of U.S. Patent No. 12,471,776, titled "ANS Assessment Systems, Kits, and Methods," further strengthening the Company's intellectual property portfolio supporting its proprietary autonomic nervous system technologies.

The newly issued patent broadly covers systems, devices and methods for monitoring physiologic signals to assess autonomic nervous system (ANS) activity, including technologies designed to evaluate sympathetic and parasympathetic nervous system function through multiple physiologic assessment techniques. The patent also encompasses technologies that may support patient selection, procedural guidance, treatment feedback and post-treatment monitoring across a broad range of neuromodulation applications.

"Our vision has always extended well beyond developing a single product. We are building a differentiated technology platform capable of transforming how physicians identify, target and treat diseases involving the peripheral nervous system," said Brad Hauser, Chief Executive Officer of Autonomix. "This newly issued patent further strengthens our innovation and technological foundation supporting that vision by protecting innovations designed to improve the precision and effectiveness of future nerve-targeted therapies. We believe Autonomix is establishing an increasingly valuable leadership position in one of the most exciting emerging areas of medical technology."

The patented technology includes systems capable of monitoring physiologic and electrophysiological signals using advanced imaging, sensors and algorithms to analyze autonomic nervous system activity. The innovations described in the patent have potential applications across numerous disease states associated with autonomic dysfunction and may provide valuable procedural feedback during nerve-targeted therapies.

The issuance of U.S. Patent No. 12,471,776 further expands Autonomix Medical's intellectual property portfolio, which continues to support the Company's differentiated technology platform focused on precision-based diagnosis and treatment of diseases involving the peripheral nervous system.

About Autonomix Medical, Inc. 

Autonomix is a medical device company focused on advancing innovative technologies to revolutionize how diseases involving the nervous system are diagnosed and treated. The Company’s first-in-class platform system technology includes a catheter-based microchip sensing array that may have the ability to detect and differentiate neural signals with greater sensitivity than currently available technologies. We believe this will enable, for the first time ever, transvascular diagnosis and treatment of diseases involving the peripheral nervous system virtually anywhere in the body. 

We are initially developing this technology for the treatment of pain, with initial trials focused on pancreatic cancer, a condition that causes debilitating pain and is without a reliable solution. Our technology constitutes a platform to address dozens of potential indications, including cardiology, hypertension and chronic pain management, across a wide disease spectrum. Our technology is investigational and has not yet been cleared for marketing in the United States. 
 
For more information, visit autonomix.com and connect with the Company on XLinkedInInstagram and Facebook.
 
Forward Looking Statements 

Some of the statements in this release are “forward-looking statements,” which involve risks and uncertainties. Such forward-looking statements can be identified by the use of words such as “should,” “might,” “may,” “intends,” “anticipates,” “believes,” “estimates,” “projects,” “forecasts,” “expects,” “plans,” and “proposes.” Forward-looking statements in this press release include, but are not limited to, expectations regarding the potential effectiveness and clinical benefits of Autonomix's nerve-targeted treatments for pancreatic cancer pain and other conditions, the versatility and scalability of the Company's platform technology, the potential for future clinical applications across multiple organ systems, the strength and scope of the Company's intellectual property portfolio, and the potential for the Company's patented technologies to support patient selection, procedural guidance and post-treatment monitoring across multiple neuromodulation applications. 
 
Although Autonomix believes that the expectations reflected in these forward-looking statements are based on reasonable assumptions, there are a number of risks and uncertainties that could cause actual results to differ materially from such forward-looking statements. You are urged to carefully review and consider any cautionary statements and other disclosures, including the statements made under the heading “Risk Factors” and elsewhere in the most recent Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission (SEC) on May 27, 2026, and from time to time, our other filings with the SEC. Forward-looking statements speak only as of the date of this press release and Autonomix does not undertake any duty to update any forward-looking statements except as may be required by law. 

Investor and Media Contact 

JTC Team, LLC 
Jenene Thomas
908.824.0775
autonomix@jtcir.com


FAQ

What did Autonomix Medical (NASDAQ: AMIX) announce on July 23, 2026?

Autonomix Medical announced the issuance of U.S. Patent No. 12,471,776 for its autonomic nervous system assessment technologies. According to Autonomix, the patent strengthens its intellectual property portfolio for precision neuromodulation and supports future applications in diagnosis, patient selection, procedural guidance and treatment monitoring.

What does U.S. Patent No. 12,471,776 cover for Autonomix Medical (AMIX)?

The patent broadly covers systems, devices and methods for monitoring physiologic signals to assess autonomic nervous system activity. According to Autonomix, it includes technologies evaluating sympathetic and parasympathetic function using multiple physiologic assessment techniques, supporting neuromodulation procedures and future nerve-targeted therapies.

How does the new ANS patent support Autonomix Medical's neuromodulation platform?

The patent supports Autonomix Medical’s precision neuromodulation platform by protecting advanced ANS assessment technologies. According to Autonomix, these technologies may guide patient selection, procedural targeting, treatment feedback and post-treatment monitoring, aiming to improve precision in peripheral nerve-targeted therapies across various disease states.

What technologies are included in Autonomix Medical's newly patented ANS assessment systems?

The patented technology includes systems capable of monitoring physiologic and electrophysiological signals using advanced imaging, sensors and algorithms. According to Autonomix, these tools analyze autonomic nervous system activity and may provide procedural feedback during nerve-targeted therapies involving the peripheral nervous system.

Why is the new ANS patent important for Autonomix Medical (AMIX) investors?

The patent expands Autonomix Medical’s intellectual property portfolio around its precision nerve-targeted technology platform. According to Autonomix, this broader protection supports its long-term vision to transform how physicians identify, target and treat diseases involving the peripheral nervous system, potentially enhancing the platform’s strategic value.

Which therapeutic areas could benefit from Autonomix Medical's patented ANS technologies?

The company states the patented innovations have potential applications across numerous disease states associated with autonomic dysfunction. According to Autonomix, they may enhance diagnosis and provide valuable procedural feedback during neuromodulation therapies targeting peripheral nerves in various clinical contexts.