Amarin Announces Preliminary 2025 Financial Highlights and Operational Accomplishments, Including Achieving Positive Cash Flow; Company Well Positioned to Capture Global Growth Opportunities

Rhea-AI Summary

Amarin (NASDAQ:AMRN) reported preliminary unaudited 2025 results and operational milestones, highlighting a year-end cash balance of $303 million, positive cash flow in Q4 2025 achieved ahead of prior expectations, and a debt-free balance sheet. The company realized ~50% of an estimated $70 million OPEX savings from its 2025 restructuring and expects the full savings by June 30, 2026. FY 2025 net revenue is expected to be $212–$217 million, with Q4 revenue of $48–$53 million. Amarin completed a long-term exclusive license and supply agreement with Recordati for VAZKEPA in 59 countries and secured regulatory approvals in South Korea and Singapore.

Positive

• Year-end cash balance of $303 million
• Positive cash flow achieved in Q4 2025
• No debt on the balance sheet
• FY 2025 net revenue expected $212–$217 million
• Exclusive Recordati partnership for 59 countries
• Realized ~50% of $70M OPEX restructuring savings

Negative

• Expected restructuring costs increased to $37–$40 million
• Full restructuring OPEX savings not realized until June 30, 2026

News Market Reaction

+16.89% 2.4x vol

25 alerts

+16.89% News Effect

+12.3% Peak in 5 hr 55 min

+$50M Valuation Impact

$343M Market Cap

2.4x Rel. Volume

On the day this news was published, AMRN gained 16.89%, reflecting a significant positive market reaction. Argus tracked a peak move of +12.3% during that session. Our momentum scanner triggered 25 alerts that day, indicating elevated trading interest and price volatility. This price movement added approximately $50M to the company's valuation, bringing the market cap to $343M at that time. Trading volume was elevated at 2.4x the daily average, suggesting notable buying interest.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

Year-end cash: $303 million Q4 2025 net revenue: $48–$53 million FY 2025 net revenue: $212–$217 million +5 more

8 metrics

Year-end cash $303 million Year-end 2025 cash balance, up from $287 million in Q3 2025

Q4 2025 net revenue $48–$53 million Preliminary Q4 2025 net revenue range

FY 2025 net revenue $212–$217 million Preliminary full-year 2025 net revenue range

Restructuring OPEX savings $70 million Estimated annual operating expense savings from 2025 restructuring

Realized savings ≈50% of $70 million Portion of restructuring OPEX savings realized in 2025

Restructuring costs (updated) $37–$40 million Expected total restructuring costs, raised from $30–$37 million

U.S. IPE share >50% VASCEPA share of IPE prescriptions at year-end 2025

VASCEPA prescriptions >25 million Cumulative global prescriptions of VASCEPA/VAZKEPA

Market Reality Check

Price: $15.42 Vol: Volume 44,539 is 50% belo...

low vol

$15.42 Last Close

Volume Volume 44,539 is 50% below 20-day average 89,762, indicating muted pre-news activity. low

Technical Price 14.03 is trading slightly below 200-day MA at 14.28, suggesting a flat longer-term trend into this update.

Peers on Argus

AMRN was up 2.48% pre-news with mixed peer moves: SCLX +1.91%, EBS +3.96%, ESPR ...

AMRN was up 2.48% pre-news with mixed peer moves: SCLX +1.91%, EBS +3.96%, ESPR +2.95%, OGN +0.61%, while KMDA fell -2.12%, pointing to stock-specific positioning rather than a unified sector trend.

Common Catalyst One peer, Organon (OGN), also reported a commercialization agreement, echoing AMRN’s focus on partnered models, but this appears isolated rather than a broad sector catalyst.

Historical Context

5 past events · Latest: Nov 09 (Positive)

Pattern 5 events

Date	Event	Sentiment	Move	Catalyst
Nov 09	Clinical data update	Positive	+0.9%	REDUCE-IT aspirin analysis showed strong event reduction in high-risk patients.
Nov 03	Conference preview	Positive	-3.9%	Announced upcoming AHA presentations on REDUCE-IT and EPA mechanisms.
Oct 29	Earnings results	Positive	-11.3%	Q3 2025 results with higher revenue and smaller losses amid restructuring.
Oct 27	Regulatory environment	Positive	-2.4%	FDA label change on fenofibrate highlighted lack of CV benefit, favoring VASCEPA.
Oct 15	Earnings call notice	Neutral	+3.4%	Announced timing and access details for upcoming Q3 2025 earnings call.

Pattern Detected

Recent AMRN news with seemingly positive implications has often seen muted or negative next-day reactions, especially around strategic and scientific updates.

Recent Company History

Over the last few months, Amarin highlighted multiple developments around VASCEPA/VAZKEPA. A new REDUCE-IT aspirin analysis on Nov 9, 2025 showed significant cardiovascular benefits and saw a modest 0.89% gain. Earlier AHA conference previews and a supportive FDA fenofibrate label change on Oct 27, 2025 both coincided with share price declines. Q3 2025 earnings on Oct 29, 2025 showed revenue growth and narrowing losses yet led to an 11.25% drop, underscoring investor caution around financial transitions.

Market Pulse Summary

The stock surged +16.9% in the session following this news. A strong positive reaction aligns with t...

Analysis

The stock surged +16.9% in the session following this news. A strong positive reaction aligns with the company’s shift to an asset-light model and confirmation of positive cash flow in Q4 2025. Investors had previously seen mixed price responses to favorable clinical and strategic updates, so a move of 5%+ would mark a break from that pattern. Key watchpoints would include execution on the targeted $70 million OPEX savings and whether revenue in 2026 sustains the preliminary $212–$217 million 2025 range.

Key Terms

icosapent ethyl, opex, pharmacy benefit manager

3 terms

icosapent ethyl medical

"Recordati S.p.A. to commercialize VAZKEPA® (icosapent ethyl) across 59 countries"

Icosapent ethyl is a prescription medicine made from a purified omega‑3 oil that lowers high levels of blood fats called triglycerides and can lower the chance of certain heart problems in patients at risk. Think of it as a focused, doctor‑prescribed version of fish oil designed to treat a specific medical condition; for investors, its regulatory approvals, patent protection, clinical evidence and market uptake drive potential drug sales and influence a health‑care company’s revenue and valuation.

opex financial

"$70M Restructuring OPEX Savings on Pace for Mid-2026"

Operating expenses (often abbreviated opex) are the day-to-day costs a company incurs to run its business, such as employee pay, rent, utilities, and routine marketing. For investors, opex matters because higher or rising operating costs reduce profits and cash available for growth or dividends, while lower or well-controlled opex can indicate better efficiency—think of it as a household’s monthly bills that determine how much is left to save or invest.

pharmacy benefit manager financial

"regained exclusive status mid-year with a large national pharmacy benefit manager"

A pharmacy benefit manager (PBM) is a company that manages prescription drug plans for health insurance providers, employers, and other organizations. They negotiate prices with drugmakers, decide which medicines are covered, and handle the distribution of prescriptions. For investors, PBMs are important because they influence healthcare costs and profit margins in the pharmacy industry.

AI-generated analysis. Not financial advice.

U.S. IPE Market Leadership Sustained; $70M Restructuring OPEX Savings on Pace for Mid-2026; Completed Transition to Fully Partnered Model Across All International Markets

DUBLIN and BRIDGEWATER, N.J., Jan. 08, 2026 (GLOBE NEWSWIRE) -- Amarin Corporation plc (NASDAQ:AMRN), a company advancing the science of cardiovascular therapeutics worldwide, today announced select preliminary unaudited 2025 financial highlights, provided a summary of key 2025 operational accomplishments, and outlined 2026 priorities in advance of business development and investor meetings in San Francisco during the week of January 12, 2026.

Creating a New Operating Paradigm from a Position of Strength
“Our preliminary results for the fourth quarter and full year 2025 represent an inflection point in the evolution of Amarin,” said Aaron Berg, Chief Executive Officer.

“We are executing our measured and strategic approach to transforming our business and unleashing its significant untapped potential. With the exclusive, long-term partnership with Recordati S.p.A. to commercialize VAZKEPA^® (icosapent ethyl) across 59 countries focused on Europe and subsequent further meaningful reduction in our operating expenses, in the fourth quarter of 2025 we achieved positive cash flow – a milestone reached earlier than previously forecasted. We believe we are on track for sustainable positive annual cash flow in 2026, driven by continued efficient revenue generation across all markets, a full year of cost savings from our restructuring plan, and the fact that the majority of the expenses associated with that plan were incurred in 2025. We have a robust cash position and debt-free balance sheet and are actively pursuing additional ways to unlock shareholder value.”

2025 Select Unaudited Financial Highlights
Balance Sheet

• Year-end 2025 cash balance of $303 million, an increase of $16 million from $287 million in Q3 2025.
• Positive cash flow in Q4 2025 achieved ahead of prior expectation of 2026.
• No debt.
  

Income Statement

• Q4 2025 net revenue expected to range between $48 - $53 million and FY 2025 net revenue expected to range between $212 - $217 million.
• Realized approximately 50% of the $70 million in estimated OPEX savings related to the 2025 restructuring; on track to realize the full estimated savings benefit by June 30, 2026, resulting in a significantly lower operating cost structure going forward.
• Expected restructuring costs to range from $37 - $40 million, up from the prior estimate of $30 - $37 million.
  

2025 Key Accomplishments
United States

• Sustained VASCEPA’s market leadership across all available IPE products (brand and generic) with year-end 2025 share greater than 50% of IPE prescriptions.
• Maintained all major managed care exclusives throughout 2025 and successfully regained exclusive status mid-year with a large national pharmacy benefit manager.

Europe

• Entered into an exclusive long-term license and supply agreement with Recordati to commercialize VAZKEPA in 59 countries, focused on Europe.
• Maintained in-market product demand growth across all commercialized European markets during the transition.
• As planned, Recordati is now fully managing European commercialization and promotion in a substantial majority of launched countries.
• Secured pricing and reimbursement in two new countries: Austria and Slovenia.
• Established regional access for more than 90% of eligible patients in Italy, thereby enabling Recordati to drive future growth.
  

ROW

• Realized increased year-over-year demand in all markets in which the Company’s in-country partners have launched.
• Secured two new regulatory approvals: South Korea and Singapore.

Scientific Advancement

• Continued to advance scientific publications:
  • Presented >10 new abstracts/posters at leading industry conferences globally.
  • Published >20 new manuscripts in peer-reviewed journals.
    

2026 Outlook - Addressing Near-Term Priorities and Long-Term Opportunities
Mr. Berg continued, “In 2025, we refined our strategy and established a fully partnered business model ex-U.S., and we now believe that we are in the best position in recent memory to capitalize on the opportunities presented by our VASCEPA/VAZKEPA franchise in 2026 and beyond.

VASCEPA/VAZKEPA has already been prescribed more than 25 million times to millions of patients globally, as part of the effort to reduce cardiovascular disease as a leading cause of death. With approvals for cardiovascular risk reduction in over 50 countries and IP protection to 2039 in Europe, Amarin is well positioned for future long-term growth. We now operate in collaboration with seven experienced and well-established partners who have access to close to 100 markets and possess regional and in-country economies of scale, robust infrastructure and extensive commercial experience. Through this asset-light commercialization strategy, we are now delivering VASCEPA in a more focused, effective, and efficient manner to an expanded international patient population.”

Mr. Berg continued, ”In 2026, our focus will be multi-pronged and multi-national and includes competing to maintain our IPE leadership in the United States and expanding our therapeutic reach across Europe and other partnered international markets, as well as realizing the full operational improvements from our restructuring initiatives. Additionally, we remain actively engaged with our exclusive financial advisor to identify future value-creating strategic opportunities that capitalize on all our strengths.

I am grateful for the commitment, collaboration, and accountability demonstrated by the Amarin team as we continue to deliver on our promise to create a globally diverse and financially disciplined organization.”

Business and Investor Meetings January 12-15, 2026
Members of Amarin’s management team will conduct business development and investor/analyst meetings surrounding the J.P. Morgan Healthcare Conference, to be held January 12-15, 2026, in San Francisco, CA. For business development meetings, please contact Eric Boothe at eric.boothe@amarincorp.com. For investor/analyst meetings, please contact Amarin investor relations at Investor.relations@amarincorp.com.

About Amarin

Amarin is a global pharmaceutical company committed to reducing the cardiovascular disease (CVD) burden for patients and communities and to advancing the science of cardiovascular care around the world. We own and support a global branded product approved by multiple regulatory authorities based on a track record of proven efficacy and safety and backed by robust clinical trial evidence. Our commercialization model includes a direct sales approach in the U.S. and an indirect distribution strategy internationally, through a syndicate of reputable and well-established partners with significant geographic expertise, covering close to 100 markets worldwide. Our success is driven by a dedicated, talented, and highly skilled team of experts passionate about the fight against the world’s leading cause of death, CV.

About VASCEPA^®/VAZKEPA^® (icosapent ethyl) Capsules
VASCEPA (icosapent ethyl) capsules are the first prescription treatment approved by the U.S. Food and Drug Administration (FDA) comprised solely of the active ingredient, icosapent ethyl (IPE), a unique form of eicosapentaenoic acid. VASCEPA was launched in the United States in January 2020 as the first drug approved by the U.S. FDA for treatment of the studied high-risk patients with persistent cardiovascular risk despite being on statin therapy. VASCEPA was initially launched in the United States in 2013 based on the drug’s initial FDA approved indication for use as an adjunct therapy to diet to reduce triglyceride levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia. Since launch, VASCEPA has been prescribed more than twenty-five million times. VASCEPA is covered by most major medical insurance plans. In addition to the United States, VASCEPA is approved and sold in Canada, China, Australia, Lebanon, the United Arab Emirates, Saudi Arabia, Qatar, Bahrain, and Kuwait. In Europe, in March 2021 marketing authorization was granted to icosapent ethyl in the European Union for the reduction of risk of cardiovascular events in patients at high cardiovascular risk, under the brand name VAZKEPA. In April 2021 marketing authorization for VAZKEPA (icosapent ethyl) was granted in the United Kingdom (applying to England, Scotland, Wales, and Northern Ireland). VAZKEPA (icosapent ethyl) is currently approved and sold in Europe in Sweden, Finland, England/Wales, Spain, Netherlands, Scotland, Greece, Portugal, Italy, Denmark and Austria.

United States Indications and Limitation of Use
VASCEPA is indicated:

• As an adjunct to maximally tolerated statin therapy to reduce the risk of myocardial infarction, stroke, coronary revascularization and unstable angina requiring hospitalization in adult patients with elevated triglyceride (TG) levels (≥ 150 mg/dL) and established cardiovascular disease or diabetes mellitus and two or more additional risk factors for cardiovascular disease.
• As an adjunct to diet to reduce TG levels in adult patients with severe (≥ 500 mg/dL) hypertriglyceridemia.

The effect of VASCEPA on the risk for pancreatitis in patients with severe hypertriglyceridemia has not been determined.

Important Safety Information 

• VASCEPA is contraindicated in patients with known hypersensitivity (e.g., anaphylactic reaction) to VASCEPA or any of its components.
• VASCEPA was associated with an increased risk (3% vs 2%) of atrial fibrillation or atrial flutter requiring hospitalization in a double-blind, placebo-controlled trial. The incidence of atrial fibrillation was greater in patients with a previous history of atrial fibrillation or atrial flutter.
• It is not known whether patients with allergies to fish and/or shellfish are at an increased risk of an allergic reaction to VASCEPA. Patients with such allergies should discontinue VASCEPA if any reactions occur.
• VASCEPA was associated with an increased risk (12% vs 10%) of bleeding in a double-blind, placebo-controlled trial. The incidence of bleeding was greater in patients receiving concomitant antithrombotic medications, such as aspirin, clopidogrel or warfarin.
• Common adverse reactions in the cardiovascular outcomes trial (incidence ≥3% and ≥1% more frequent than placebo): musculoskeletal pain (4% vs 3%), peripheral edema (7% vs 5%), constipation (5% vs 4%), gout (4% vs 3%), and atrial fibrillation (5% vs 4%).
• Common adverse reactions in the hypertriglyceridemia trials (incidence >1% more frequent than placebo): arthralgia (2% vs 1%) and oropharyngeal pain (1% vs 0.3%).
• Adverse events may be reported by calling 1-855-VASCEPA or the FDA at 1-800-FDA-1088.
• Patients receiving VASCEPA and concomitant anticoagulants and/or anti-platelet agents should be monitored for bleeding.

FULL U.S. FDA-APPROVED VASCEPA PRESCRIBING INFORMATION CAN BE FOUND AT WWW.VASCEPA.COM

Europe 
For further information about the Summary of Product Characteristics (SmPC) for VAZKEPA^® in Europe, please visit: https://www.ema.europa.eu/en/documents/product-information/vazkepa-epar-product-information_en.pdf

Globally, prescribing information varies; refer to the individual country product label for complete information.

Forward-Looking Statements
This press release contains forward-looking statements which are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, including beliefs about Amarin’s key achievements in 2025 and the potential impact and outlook for achievements in 2026 and beyond; Amarin’s 2025 financial outlook and cash position; Amarin’s overall efforts to expand access and reimbursement to VAZKEPA across global markets; expectations regarding potential strategic collaboration and licensing agreements with third parties, including our ability to attract additional collaborators, as well as our plans and strategies for entering into potential strategic collaboration and licensing agreements and the overall potential and future success of VASCEPA/VAZKEPA and Amarin that are based on the beliefs and assumptions and information currently available to Amarin.

All statements other than statements of historical fact contained in this press release are forward-looking statements. These forward-looking statements are not promises or guarantees and involve substantial risks and uncertainties. A further list and description of these risks, uncertainties and other risks associated with an investment in Amarin can be found in Amarin's filings with the U.S. Securities and Exchange Commission, including Amarin’s quarterly report on Form 10-Q for the period ending September 30, 2025 and annual report on Form 10-K for the fiscal year ended 2024. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date they are made. Amarin undertakes no obligation to update or revise the information contained in its forward-looking statements, whether as a result of new information, future events or circumstances or otherwise. Amarin’s forward-looking statements do not reflect the potential impact of significant transactions the company may enter into, such as mergers, acquisitions, dispositions, joint ventures or any material agreements that Amarin may enter into, amend or terminate. Investors and others should note that Amarin communicates with its investors and the public using the company website (www.amarincorp.com), the investor relations website (www.amarincorp.com/investor-relations), including but not limited to investor presentations and investor FAQs, U.S. Securities and Exchange Commission filings, press releases, public conference calls and webcasts.

Amarin Contact Information
Media Inquiries:
Tegan Berry
Amarin Corporation plc
PR@amarincorp.com

Investor Inquiries:
Bob Burrows
Western Avenue Advisers LLC
bob.burrows.ext@amarincorp.com
Investor.relations@amarincorp.com

FAQ

What cash position did Amarin (AMRN) report at year-end 2025?

Amarin reported a year-end 2025 cash balance of $303 million.

Did Amarin (AMRN) achieve positive cash flow in 2025?

Yes; Amarin achieved positive cash flow in Q4 2025, earlier than previously expected.

What revenue did Amarin (AMRN) report for FY 2025 in the preliminary update?

FY 2025 net revenue was preliminarily expected to be $212–$217 million.

What is the scope of Amarin’s partnership with Recordati for VAZKEPA?

Amarin entered an exclusive long-term license and supply agreement with Recordati to commercialize VAZKEPA in 59 countries, focused on Europe.

How much OPEX savings did Amarin (AMRN) realize from its 2025 restructuring?

Amarin realized approximately 50% of the estimated $70 million in OPEX savings and expects full benefit by June 30, 2026.

What restructuring costs did Amarin (AMRN) disclose for 2025?

Amarin expects restructuring costs to range from $37–$40 million, up from the prior estimate of $30–$37 million.