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Amwell Will Support New Federally Funded Research to Improve Engagement and Outcomes in Mental Health Care for Veterans and Service Members

Federal awards support two SilverCloud trials that will reach over a thousand patients over five years.

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Amwell (AMWL) announced a research agreement with UCLA to study digital depression care for veterans and service members transitioning out of service. SilverCloud, its digital cognitive behavioral therapy program, will feature in two randomized controlled trials supported by federal awards totaling nearly $16.8 million; that total is not an award to Amwell.

The trials will reach over a thousand patients over five years, examining engagement and integration into existing care. Recruitment began in October 2026 for the Department of War-funded effort and is expected to begin soon after for the VA-supported effort. The VA research focuses on expanding virtual care for rural veterans. Neither agency endorses any commercial product.

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Positive

  • Minor pointUCLA research agreement puts SilverCloud into two federally supported randomized controlled trials.
  • Minor point. Forward-looking: it has not happened yet and may not happen.Federal awards totaling nearly $16.8 million support research over up to five years, including SilverCloud studies.
  • Minor point. Forward-looking: it has not happened yet and may not happen.CDMRP research will support 400 veterans and transitioning military members, evaluating depression care with primary-care and peer support.
  • Minor point. Forward-looking: it has not happened yet and may not happen.VA QUERI research will examine expanding virtual care for rural veterans, with SilverCloud supporting its digital therapy component.
  • Minor pointIndependent 2026 trial across 26 U.S. colleges and universities reported two times higher care participation versus screening and in-person referral.
  • Minor pointThe same trial reported lower prevalence of measured mental disorders over a 2-year period versus that comparator.

Negative

  • None.
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Key Figures

Combined federal awards: Nearly $16.8 million DoW CDMRP grant: $2,923,778 VA QUERI Center award: Over $13.8 million +4 more
Combined federal awards
Nearly $16.8 million
Funding for the two research efforts
DoW CDMRP grant
$2,923,778
Grant supporting one research effort
VA QUERI Center award
Over $13.8 million
The research receives a part of this award
CDMRP study participants
400 veterans and transitioning service members
Participants supported by the CDMRP grant
Trials
Two randomized controlled trials
Both involve SilverCloud
Combined patient reach
Over 1,000 patients
Across both research efforts
Research period
Up to five years
Duration supported by the awards

Key Terms

cognitive behavioral therapy, randomized controlled trials
2 terms
cognitive behavioral therapy medical
"digital cognitive behavioral therapy program delivered on the Amwell Platform"
A structured, time-limited form of psychotherapy that teaches people to identify and change unhelpful thoughts and behaviors that contribute to emotional distress or functional problems. It combines techniques for testing and reframing negative thinking with practical skills and behavioral experiments (for example, gradual exposure or activity scheduling) to change patterns that maintain anxiety, depression, or other mental-health conditions; it is delivered by trained therapists and is distinct from medication or purely insight-oriented therapies.
randomized controlled trials technical
"fund two randomized controlled trials involving SilverCloud"
Randomized controlled trials are studies where participants are randomly assigned to receive either a new treatment or a comparison (such as a standard treatment or placebo), so outcomes can be fairly compared like flipping a coin to decide teams. For investors, they matter because they provide the most reliable evidence about whether a drug, device or intervention actually works and is safe, which influences regulatory approval, market demand and the financial outlook of companies developing them.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Two major federal awards totaling nearly $16.8 million will support research over a period of up to five years, including research examining how SilverCloud by Amwell, the digital cognitive behavioral therapy program on the Amwell Platform, can support engagement in depression care

BOSTON, Nov. 10, 2026 (GLOBE NEWSWIRE) -- Amwell® (NYSE: AMWL) today announced a research agreement with The University of California, Los Angeles (UCLA) to study how digital mental health support can help veterans and transitioning service members connect with care for depression. This work leverages SilverCloud® by Amwell®, the digital cognitive behavioral therapy program delivered on the Amwell Platform, in research supported by the U.S. Department of Veterans Affairs (VA) and Department of War (DoW). The VA and DoW do not endorse any commercial product.

Led by Lucinda B. Leung, MD, PhD, MPH, associate professor of medicine and psychiatry at UCLA, the research will examine how digital cognitive behavioral therapy (cCBT) can be integrated into existing care. The work is supported by two major federal awards: a $2,923,778 DoW Congressionally Directed Medical Research Programs (CDMRP) grant and a part of an over $13.8 million VA Quality Enhancement Research Initiative (QUERI) Center award.

Depression is a leading cause of disability worldwide, and symptoms affect approximately 1 in 5 veterans. Barriers to mental health care access are most profound, and depression treatment most limited among veterans living in rural and far-reaching locales. More than 4.4 million veterans live in rural communities, where distance and limited provider availability can make depression care difficult to obtain, according to the VA. Internet-based cCBT may be a viable and effective option for addressing these barriers and improving the VA’s capacity to deliver evidence-based psychotherapy to rural veterans with depression. However, low uptake suggests that passive availability is insufficient to ensure veteran and service member engagement. Closing that gap between access and use is the question at the center of this research.

“Digital mental health tools can help us reach people who face barriers to care, but we need to understand how to make them work within the care people already receive,” said Leung. “Our goal is to learn which approaches most help veterans and transitioning service members to engage with treatment for depression and help us to sustain that engagement over time.”

The research will study how cognitive behavioral therapy-based digital programs, with structured content and interactive tools accessible on a smartphone, tablet or computer, can support engagement in depression care. The study will examine how digitally delivered cCBT programs fit best into existing VA clinical services and what support will be most helpful to people using them.

“We are encouraged by the growing body of evidence on the impact of the SilverCloud program of the Amwell Platform, working alongside the rest of the programs our clients offer,” said Ido Schoenberg, MD, chairman and CEO of Amwell. “That this research is being done for veterans makes it especially important. We are proud to serve these incredibly important men and women, and pleased that world-class researchers will invest their effort and expertise to further improve outcomes.”

The collaboration encompasses two complementary research efforts. The CDMRP grant will support 400 veterans and military members transitioning out of service, evaluating cCBT within depression care, including support from primary care teams and veteran peers. The VA QUERI award supports research on expanding virtual care for veterans in rural areas. SilverCloud will be featured in both efforts and supports the digital cCBT component of that broader program. Together, the grants will fund two randomized controlled trials involving SilverCloud and will reach over a thousand patients over five years.

Participant recruitment began in October 2026 for CDMRP and is expected to begin soon after for QUERI. The collaboration builds on Amwell’s work supporting military and veteran communities, including technology for the Military Health System’s Digital First program. The work also adds to SilverCloud’s growing body of evidence on engagement and outcomes. A separate, independently led, randomized trial published in Nature Human Behaviour in 2026 examined SilverCloud across 26 U.S. colleges and universities and reported two times higher participation in care and lower prevalence of measured mental disorders over a 2-year period compared with screening and referral to in-person care.

The studies build on nearly two decades of SilverCloud research, including more than 50 peer-reviewed publications and collaborations with Harvard Medical School, Trinity College Dublin, and Boston University. SilverCloud programs have been studied across populations in the United States, the United Kingdom and Ireland.

SilverCloud is one program on the Amwell Platform, where it is available alongside Amwell Therapy and Amwell Psychiatry. Through the Amwell Platform, members access care through a unified experience under their health plan’s brand. The platform is designed to simplify discovery, navigation and enrollment across Amwell services and plan-selected third-party programs, and to route each member to the right covered service with less friction. Connected clinical pathways support stepped care, from self-paced digital programs for lower-acuity needs to clinician-led therapy and psychiatry when clinically appropriate, and help members reach primary, urgent and specialty care as their needs change. This stepped care approach, offered through a unified experience, is designed to give health plans, government agencies and employers a clear view of engagement and outcomes across the member care journey.

About Amwell
Amwell® (NYSE: AMWL) helps health plans, healthcare organizations and government agencies deliver connected, technology-enabled care that improves clinical and financial outcomes. The Amwell Platform connects consumer experiences, clinician workflows and clinical programs from Amwell and its partners to simplify access, strengthen engagement, deliver care reliably and support effective care across the continuum.

For two decades, Amwell has served some of the largest and most sophisticated healthcare organizations in the U.S. and worldwide, enabling care for millions. Recent recognition includes Frost & Sullivan’s 2026 United States Technology Innovation Leadership Recognition for technology-enabled care platforms, inclusion in TIME’s World’s Top HealthTech Companies of 2026, and selection as a quarterfinalist in the 2026 Digital Health & AI Awards.

For more information, visit business.amwell.com or LinkedIn (linkedin.com/company/amwellcorp).

Forward-Looking Statements

This press release contains forward-looking statements about us and our industry that involve substantial risks and uncertainties and are based on our beliefs and assumptions and on information currently available to us. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations, financial condition, business strategy and plans and objectives of management for future operations, are forward-looking statements. In some cases, you can identify forward-looking statements because they contain words such as “anticipate,” “believe,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “will,” or “would,” or the negative of these words or other similar terms or expressions.

Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Forward-looking statements represent our beliefs and assumptions only as of the date of this release. These statements, and related risks, uncertainties, factors and assumptions, include, but are not limited to: our ability to successfully transition our clients to our current platform without significant attrition; our ability to renew and upsell our client base; the election by the Defense Health Agency to deploy our solution across their entire enterprise; the continuation of the DHA relationship beyond Q3 2026 with comparable financial terms; weak growth and increased volatility in the telehealth market; our ability to adapt to rapid technological changes; increased competition from existing and potential new participants in the healthcare industry; changes in healthcare laws, regulations or trends and our ability to operate in the heavily regulated healthcare industry; our ability to comply with federal and state privacy regulations; the significant liability that could result from a cybersecurity breach; our ability to commence and complete and strategic transformation initiatives and the impact of such initiatives; and other factors described under ‘Risk Factors’ in our most recent form 10-K filed with the SEC. These risks are not exhaustive. Except as required by law, we assume no obligation to update these forward-looking statements, or to update the reasons actual results could differ materially from those anticipated in the forward-looking statements, even if new information becomes available in the future. Further information on factors that could cause actual results to differ materially from the results anticipated by our forward-looking statements is included in the reports we have filed or will file with the Securities and Exchange Commission. These filings, when available, are available on the investor relations section of our website at investors.amwell.com and on the SEC’s website at www.sec.gov.

Media contacts
Amwell: press@amwell.com

Investor contact
Amwell: Asher Dewhurst, amwell@icrhealthcare.com


FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What will Amwell and UCLA study using SilverCloud?

The research will examine how SilverCloud digital cognitive behavioral therapy can support engagement in depression care for veterans and transitioning service members. Two randomized controlled trials will study how digital treatment fits into existing care and what support helps people use it.

How are the Amwell SilverCloud studies with UCLA funded?

The work is supported by a $2,923,778 Department of War CDMRP grant and part of an over $13.8 million VA QUERI Center award. SilverCloud supports the digital cognitive behavioral therapy component of the broader VA program; the full awards are not described as payments to Amwell.

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