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Bioxytran’s Groundbreaking Stroke & Alzheimer’s Tech Gains Validation That Measures Oxygenation Uptake During Strokes

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Bioxytran (OTCQB: BIXT) announced the publication of a groundbreaking book by Science Advisor Prof. Avraham Mayevsky focusing on Mongolian Gerbil brain research, which validates their clinical development program for stroke and Alzheimer's treatment. The research centers on their universal oxygen carrier (UOC) technology and FDA-approved MDX Viewer for measuring tissue oxygenation. The UOC aims to replace hyperbaric oxygen treatment by delivering therapeutic oxygen at the cellular level, avoiding harmful reactive oxygen species. The Mongolian gerbil model is particularly valuable due to its unique brain vasculature that lacks compensatory mechanisms during stroke, making it ideal for studying stroke pathophysiology and testing treatment efficacy.
Bioxytran (OTCQB: BIXT) ha annunciato la pubblicazione di un libro innovativo scritto dal Consigliere Scientifico Prof. Avraham Mayevsky, che si concentra sulla ricerca cerebrale del gerbillo della Mongolia e convalida il loro programma di sviluppo clinico per il trattamento dell'ictus e dell'Alzheimer. La ricerca si basa sulla loro tecnologia universale di trasporto dell'ossigeno (UOC) e sull'MDX Viewer approvato dalla FDA per la misurazione dell'ossigenazione tissutale. L'UOC mira a sostituire il trattamento con ossigeno iperbarico fornendo ossigeno terapeutico a livello cellulare, evitando la formazione di specie reattive dell'ossigeno dannose. Il modello del gerbillo della Mongolia è particolarmente prezioso grazie alla sua vascolarizzazione cerebrale unica, priva di meccanismi compensatori durante l'ictus, rendendolo ideale per studiare la fisiopatologia dell'ictus e testare l'efficacia dei trattamenti.
Bioxytran (OTCQB: BIXT) anunció la publicación de un libro innovador escrito por el Asesor Científico Prof. Avraham Mayevsky, centrado en la investigación cerebral del jerbo mongol, que valida su programa clínico de desarrollo para el tratamiento del ictus y el Alzheimer. La investigación se basa en su tecnología universal de transporte de oxígeno (UOC) y en el MDX Viewer aprobado por la FDA para medir la oxigenación tisular. La UOC busca reemplazar el tratamiento con oxígeno hiperbárico al suministrar oxígeno terapéutico a nivel celular, evitando especies reactivas de oxígeno dañinas. El modelo del jerbo mongol es especialmente valioso debido a su vasculatura cerebral única, que carece de mecanismos compensatorios durante el ictus, lo que lo hace ideal para estudiar la fisiopatología del ictus y evaluar la eficacia de los tratamientos.
Bioxytran(OTCQB: BIXT)는 과학 자문위원인 Avraham Mayevsky 교수가 쓴 획기적인 책 출판을 발표했습니다. 이 책은 몽골 저빌의 뇌 연구에 중점을 두고 있으며, 뇌졸중과 알츠하이머 치료를 위한 임상 개발 프로그램을 검증합니다. 연구는 그들의 범용 산소 운반체(UOC) 기술과 FDA 승인된 조직 산소 측정기 MDX Viewer를 중심으로 진행됩니다. UOC는 세포 수준에서 치료용 산소를 공급하여 유해한 활성 산소종 생성을 피함으로써 고압 산소 치료를 대체하는 것을 목표로 합니다. 몽골 저빌 모델은 뇌졸중 시 보상 기전이 없는 독특한 뇌 혈관 구조 덕분에 뇌졸중 병태생리 연구와 치료 효능 평가에 이상적인 모델입니다.
Bioxytran (OTCQB : BIXT) a annoncé la publication d'un ouvrage révolutionnaire rédigé par le conseiller scientifique Prof. Avraham Mayevsky, axé sur la recherche cérébrale du gerbille de Mongolie, validant leur programme de développement clinique pour le traitement de l'AVC et de la maladie d'Alzheimer. La recherche porte sur leur technologie universelle de transport d'oxygène (UOC) et le MDX Viewer approuvé par la FDA pour mesurer l'oxygénation tissulaire. L'UOC vise à remplacer le traitement à l'oxygène hyperbare en délivrant de l'oxygène thérapeutique au niveau cellulaire, évitant ainsi la formation d'espèces réactives de l'oxygène nuisibles. Le modèle du gerbille de Mongolie est particulièrement précieux en raison de sa vascularisation cérébrale unique, dépourvue de mécanismes compensatoires lors d'un AVC, ce qui en fait un modèle idéal pour étudier la physiopathologie de l'AVC et tester l'efficacité des traitements.
Bioxytran (OTCQB: BIXT) gab die Veröffentlichung eines bahnbrechenden Buches bekannt, verfasst vom Wissenschaftlichen Berater Prof. Avraham Mayevsky, das sich auf die Gehirnforschung am mongolischen Wüstenrennmaus-Modell konzentriert und ihr klinisches Entwicklungsprogramm für Schlaganfall- und Alzheimer-Behandlungen bestätigt. Die Forschung basiert auf ihrer universellen Sauerstoffträger-Technologie (UOC) und dem von der FDA zugelassenen MDX Viewer zur Messung der Gewebeoxygenierung. Die UOC soll die hyperbare Sauerstofftherapie ersetzen, indem sie therapeutischen Sauerstoff auf zellulärer Ebene liefert und schädliche reaktive Sauerstoffspezies vermeidet. Das Modell der mongolischen Wüstenrennmaus ist besonders wertvoll aufgrund seiner einzigartigen Gehirngefäßstruktur, die während eines Schlaganfalls keine Kompensationsmechanismen aufweist, was es ideal macht, um die Pathophysiologie des Schlaganfalls zu untersuchen und die Wirksamkeit von Behandlungen zu testen.
Positive
  • FDA-approved MDX Viewer technology for measuring tissue oxygenation
  • Scientific validation of clinical development program through published research
  • Potential breakthrough in stroke and Alzheimer's treatment with UOC technology
  • Unique testing model using Mongolian gerbil brain provides strong predictive value for clinical trials
Negative
  • Company still in clinical stage with unproven commercial products
  • Trading on OTCQB market indicates early-stage development status

Mongolian Gerbil Research Unlocks Critical Insights for Ischemic Stroke and Neurodegenerative Disease Treatments

BOSTON, MASSACHUSETTS, June 03, 2025 (GLOBE NEWSWIRE) -- BIOXYTRAN, INC. (OTCQB: BIXT) (the “Company”), a clinical stage biotechnology company developing drugs to treat stroke and Alzheimer's disease, announced that Bioxtran’s Science Advisor Prof. Avraham Mayevsky’s book titled The Mongolian Gerbil Brain: Mitochondrial Function, Vasculature, and Pathophysiological States was published by a publishing house, Springer. It is available by eBook or Hardcover. The publication serves as a scientific cornerstone for Bioxytran’s clinical development program of the universal oxygen carrier (UOC) in ischemic stroke and Alzheimer’s disease, and is directly tied to the use of the MDX Viewer as an analytical method to detect a brain regions response to the addition of a UOC. The device has FDA approval to measure tissue oxygenation.

https://link.springer.com/book/10.1007/978-3-031-69549-0

Bioxytran is pioneering a transformative approach to treating ischemic stroke and neurodegenerative disease. The UOC is capable of replacing hyperbaric oxygen treatment (HBOT) by efficiently delivering therapeutic type of oxygen at the cellular level versus a charged version of oxygen prevalent in HBOT treatment called reactive oxygen species (ROS). This breakthrough is powered by the MDX viewer that provides real-time metabolic insights – a crucial element of Bioxytran’s regulatory approach.

The Mongolian gerbil brain is special in that it lacks the vasculature compensatory mechanisms that can deal with decreased blood flow in the event of a stroke. Since the blood vessels in the Mongolian gerbil brain have no coping mechanism it makes them ideal in studying stroke pathophysiology. The research compiled in this publication further validates Bioxytran’s scientific and clinical approach, positioning the company on the cutting edge of advancements in brain health and neuroprotective treatments.

“This research is paving the way for substantial advances in the understanding of the pathology of stroke and other neurodegenerative diseases, said Avraham Mayevsky, Member of Bioxytran’s Medical Advisory Board. “One of the biggest challenges in in clinical trials is determining the efficacy of a drug. This gerbil brain model has great predictive value in ischemic stroke and Alzheimer’s disease. The gerbil model coupled with the MDX Viewer will provide us amazing insight in the pathogenesis of stroke and neurodegenerative diseases. Over 60 years went toward the development of the book which highlights a model of how brain anomalies are detected using this device.”

About Bioxytran, Inc.

Bioxytran, Inc. is at the forefront of developing complex carbohydrate-based therapeutics to address critical unmet medical needs in its three core platform technologies. These include virology, cancer metastasis, and oxygen transport. In addition to ProLectin-M, Bioxytran is advancing programs for pulmonary fibrosis and stroke treatment. When utilized by paramedics at the time of diagnosis BXT-25 has the possibility of reducing what is known as the time until needle by over 90%. For more information, visit www.bioxytraninc.com

Investor Relations
Michael Sheikh
509-991-0245
mike.sheikh@bioxytraninc.com

Forward-Looking Statements

This press release includes forward-looking statements as defined under federal law, including those related to the performance of technology described in this press release. These forward-looking statements are generally identified by the words “believe,” “expect,” “anticipate,” “estimate,” “intend,” “plan,” and similar expressions, although not all forward-looking statements contain these identifying words. Such statements are subject to significant risks, assumptions and uncertainties. Known material factors that could cause Bioxytran’s actual results to differ materially from the results contemplated by such forward-looking statements are described in the forward-looking statements and risk factors in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2023, and those risk factors set forth from time-to-time in other filings with the Securities and Exchange Commission. Bioxytran undertakes no obligation to correct or update any forward-looking statement, whether as a result of new information, future events, or otherwise, except to the extent required under federal securities laws.


FAQ

What is Bioxytran's (BIXT) new breakthrough in stroke and Alzheimer's treatment?

Bioxytran has developed a universal oxygen carrier (UOC) that can replace hyperbaric oxygen treatment by delivering therapeutic oxygen at the cellular level, validated through Mongolian gerbil brain research and monitored by their FDA-approved MDX Viewer.

How does BIXT's MDX Viewer technology work in stroke treatment?

The FDA-approved MDX Viewer provides real-time metabolic insights by measuring tissue oxygenation, crucial for monitoring treatment effectiveness in stroke and neurodegenerative diseases.

Why is the Mongolian gerbil brain model significant for BIXT's research?

The Mongolian gerbil brain lacks vasculature compensatory mechanisms during decreased blood flow, making it ideal for studying stroke pathophysiology and testing treatment efficacy.

What advantages does Bioxytran's UOC technology offer over hyperbaric oxygen treatment?

BIXT's UOC delivers therapeutic oxygen at the cellular level, avoiding harmful reactive oxygen species (ROS) that are prevalent in hyperbaric oxygen treatment.

What is the current development stage of Bioxytran's stroke treatment?

Bioxytran is currently in the clinical stage of development, with their approach validated through published research but still working toward commercial products.
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