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Bioxytran’s Groundbreaking Stroke & Alzheimer’s Tech Gains Validation That Measures Oxygenation Uptake During Strokes

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Bioxytran (OTCQB: BIXT) announced the publication of a groundbreaking book by Science Advisor Prof. Avraham Mayevsky focusing on Mongolian Gerbil brain research, which validates their clinical development program for stroke and Alzheimer's treatment. The research centers on their universal oxygen carrier (UOC) technology and FDA-approved MDX Viewer for measuring tissue oxygenation. The UOC aims to replace hyperbaric oxygen treatment by delivering therapeutic oxygen at the cellular level, avoiding harmful reactive oxygen species. The Mongolian gerbil model is particularly valuable due to its unique brain vasculature that lacks compensatory mechanisms during stroke, making it ideal for studying stroke pathophysiology and testing treatment efficacy.
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Positive

  • FDA-approved MDX Viewer technology for measuring tissue oxygenation
  • Scientific validation of clinical development program through published research
  • Potential breakthrough in stroke and Alzheimer's treatment with UOC technology
  • Unique testing model using Mongolian gerbil brain provides strong predictive value for clinical trials

Negative

  • Company still in clinical stage with unproven commercial products
  • Trading on OTCQB market indicates early-stage development status

News Market Reaction 1 Alert

+6.47% News Effect

On the day this news was published, BIXT gained 6.47%, reflecting a notable positive market reaction.

Data tracked by StockTitan Argus on the day of publication.

Mongolian Gerbil Research Unlocks Critical Insights for Ischemic Stroke and Neurodegenerative Disease Treatments

BOSTON, MASSACHUSETTS, June 03, 2025 (GLOBE NEWSWIRE) -- BIOXYTRAN, INC. (OTCQB: BIXT) (the “Company”), a clinical stage biotechnology company developing drugs to treat stroke and Alzheimer's disease, announced that Bioxtran’s Science Advisor Prof. Avraham Mayevsky’s book titled The Mongolian Gerbil Brain: Mitochondrial Function, Vasculature, and Pathophysiological States was published by a publishing house, Springer. It is available by eBook or Hardcover. The publication serves as a scientific cornerstone for Bioxytran’s clinical development program of the universal oxygen carrier (UOC) in ischemic stroke and Alzheimer’s disease, and is directly tied to the use of the MDX Viewer as an analytical method to detect a brain regions response to the addition of a UOC. The device has FDA approval to measure tissue oxygenation.

https://link.springer.com/book/10.1007/978-3-031-69549-0

Bioxytran is pioneering a transformative approach to treating ischemic stroke and neurodegenerative disease. The UOC is capable of replacing hyperbaric oxygen treatment (HBOT) by efficiently delivering therapeutic type of oxygen at the cellular level versus a charged version of oxygen prevalent in HBOT treatment called reactive oxygen species (ROS). This breakthrough is powered by the MDX viewer that provides real-time metabolic insights – a crucial element of Bioxytran’s regulatory approach.

The Mongolian gerbil brain is special in that it lacks the vasculature compensatory mechanisms that can deal with decreased blood flow in the event of a stroke. Since the blood vessels in the Mongolian gerbil brain have no coping mechanism it makes them ideal in studying stroke pathophysiology. The research compiled in this publication further validates Bioxytran’s scientific and clinical approach, positioning the company on the cutting edge of advancements in brain health and neuroprotective treatments.

“This research is paving the way for substantial advances in the understanding of the pathology of stroke and other neurodegenerative diseases, said Avraham Mayevsky, Member of Bioxytran’s Medical Advisory Board. “One of the biggest challenges in in clinical trials is determining the efficacy of a drug. This gerbil brain model has great predictive value in ischemic stroke and Alzheimer’s disease. The gerbil model coupled with the MDX Viewer will provide us amazing insight in the pathogenesis of stroke and neurodegenerative diseases. Over 60 years went toward the development of the book which highlights a model of how brain anomalies are detected using this device.”

About Bioxytran, Inc.

Bioxytran, Inc. is at the forefront of developing complex carbohydrate-based therapeutics to address critical unmet medical needs in its three core platform technologies. These include virology, cancer metastasis, and oxygen transport. In addition to ProLectin-M, Bioxytran is advancing programs for pulmonary fibrosis and stroke treatment. When utilized by paramedics at the time of diagnosis BXT-25 has the possibility of reducing what is known as the time until needle by over 90%. For more information, visit www.bioxytraninc.com

Investor Relations
Michael Sheikh
509-991-0245
mike.sheikh@bioxytraninc.com

Forward-Looking Statements

This press release includes forward-looking statements as defined under federal law, including those related to the performance of technology described in this press release. These forward-looking statements are generally identified by the words “believe,” “expect,” “anticipate,” “estimate,” “intend,” “plan,” and similar expressions, although not all forward-looking statements contain these identifying words. Such statements are subject to significant risks, assumptions and uncertainties. Known material factors that could cause Bioxytran’s actual results to differ materially from the results contemplated by such forward-looking statements are described in the forward-looking statements and risk factors in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2023, and those risk factors set forth from time-to-time in other filings with the Securities and Exchange Commission. Bioxytran undertakes no obligation to correct or update any forward-looking statement, whether as a result of new information, future events, or otherwise, except to the extent required under federal securities laws.


FAQ

What is Bioxytran's (BIXT) new breakthrough in stroke and Alzheimer's treatment?

Bioxytran has developed a universal oxygen carrier (UOC) that can replace hyperbaric oxygen treatment by delivering therapeutic oxygen at the cellular level, validated through Mongolian gerbil brain research and monitored by their FDA-approved MDX Viewer.

How does BIXT's MDX Viewer technology work in stroke treatment?

The FDA-approved MDX Viewer provides real-time metabolic insights by measuring tissue oxygenation, crucial for monitoring treatment effectiveness in stroke and neurodegenerative diseases.

Why is the Mongolian gerbil brain model significant for BIXT's research?

The Mongolian gerbil brain lacks vasculature compensatory mechanisms during decreased blood flow, making it ideal for studying stroke pathophysiology and testing treatment efficacy.

What advantages does Bioxytran's UOC technology offer over hyperbaric oxygen treatment?

BIXT's UOC delivers therapeutic oxygen at the cellular level, avoiding harmful reactive oxygen species (ROS) that are prevalent in hyperbaric oxygen treatment.

What is the current development stage of Bioxytran's stroke treatment?

Bioxytran is currently in the clinical stage of development, with their approach validated through published research but still working toward commercial products.
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