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Bioxytran Secures a Source of GMP Quality Camel Hemoglobin

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Bioxytran (OTCQB: BIXT) has secured a GMP quality source of camel hemoglobin through a partnership with the Heme Foundation in a $10 million Joint Venture to develop a Universal Oxygen Carrier (UOC). Camel hemoglobin was chosen for its unique properties, including higher stability, resilience, and concentration compared to cow hemoglobin, with no risk of mad cow disease. The partnership grants Bioxytran full intellectual property rights for UOC development, which could enhance their leading oxygen transport molecule BXT-25, designed to treat conditions like stroke, dementia, Traumatic Brain Injury, and Alzheimer's Disease. This supply agreement represents a strategic milestone that could accelerate non-dilutive funding and advance oxygen transport technology development.
Bioxytran (OTCQB: BIXT) ha ottenuto una fonte di emoglobina di cammello di qualità GMP grazie a una partnership con la Heme Foundation, in un Joint Venture da 10 milioni di dollari per sviluppare un Trasportatore Universale di Ossigeno (UOC). L'emoglobina di cammello è stata scelta per le sue proprietà uniche, tra cui maggiore stabilità, resistenza e concentrazione rispetto all'emoglobina bovina, senza rischi di encefalopatia spongiforme bovina. La collaborazione concede a Bioxytran pieni diritti di proprietà intellettuale per lo sviluppo dell'UOC, che potrebbe potenziare la loro molecola leader per il trasporto di ossigeno, BXT-25, progettata per trattare condizioni come ictus, demenza, trauma cranico e Alzheimer. Questo accordo di fornitura rappresenta una tappa strategica che potrebbe accelerare il finanziamento non diluitivo e promuovere lo sviluppo della tecnologia di trasporto dell'ossigeno.
Bioxytran (OTCQB: BIXT) ha asegurado una fuente de hemoglobina de camello de calidad GMP mediante una asociación con la Fundación Heme en una empresa conjunta valorada en 10 millones de dólares para desarrollar un Transportador Universal de Oxígeno (UOC). Se eligió la hemoglobina de camello por sus propiedades únicas, incluyendo mayor estabilidad, resistencia y concentración en comparación con la hemoglobina bovina, sin riesgo de enfermedad de las vacas locas. La asociación otorga a Bioxytran plenos derechos de propiedad intelectual para el desarrollo del UOC, que podría mejorar su molécula líder de transporte de oxígeno, BXT-25, diseñada para tratar afecciones como accidente cerebrovascular, demencia, lesiones cerebrales traumáticas y enfermedad de Alzheimer. Este acuerdo de suministro representa un hito estratégico que podría acelerar la financiación no dilutiva y avanzar en el desarrollo de la tecnología de transporte de oxígeno.
Bioxytran(OTCQB: BIXT)는 Heme 재단과의 1,000만 달러 합작 투자로 GMP 품질의 낙타 헤모글로빈 공급원을 확보하여 범용 산소 운반체(UOC)를 개발하고 있습니다. 낙타 헤모글로빈은 소 헤모글로빈에 비해 더 높은 안정성, 내구성, 농도를 지니며 광우병 위험이 없다는 독특한 특성 때문에 선택되었습니다. 이 파트너십은 Bioxytran에 UOC 개발에 대한 완전한 지적 재산권을 부여하며, 이는 뇌졸중, 치매, 외상성 뇌손상 및 알츠하이머병과 같은 질환 치료를 위해 설계된 선도적 산소 운반 분자 BXT-25를 강화할 수 있습니다. 이 공급 계약은 비희석 자금 조달을 가속화하고 산소 운반 기술 개발을 진전시킬 수 있는 전략적 이정표를 의미합니다.
Bioxytran (OTCQB : BIXT) a obtenu une source d'hémoglobine de chameau de qualité GMP grâce à un partenariat avec la Heme Foundation dans le cadre d'une coentreprise de 10 millions de dollars visant à développer un transporteur universel d'oxygène (UOC). L'hémoglobine de chameau a été choisie pour ses propriétés uniques, notamment une stabilité, une résilience et une concentration supérieures à celles de l'hémoglobine bovine, sans risque d'encéphalopathie spongiforme bovine. Ce partenariat accorde à Bioxytran l'intégralité des droits de propriété intellectuelle pour le développement de l'UOC, qui pourrait améliorer leur molécule de transport d'oxygène phare, BXT-25, conçue pour traiter des affections telles que l'AVC, la démence, les traumatismes crâniens et la maladie d'Alzheimer. Cet accord d'approvisionnement constitue une étape stratégique susceptible d'accélérer le financement non dilutif et de faire progresser le développement de la technologie de transport de l'oxygène.
Bioxytran (OTCQB: BIXT) hat durch eine Partnerschaft mit der Heme Foundation eine GMP-qualitative Quelle für Kamelhämoglobin gesichert. In einem Joint Venture im Wert von 10 Millionen US-Dollar wird ein Universeller Sauerstoffträger (UOC) entwickelt. Kamelhämoglobin wurde aufgrund seiner einzigartigen Eigenschaften ausgewählt, darunter höhere Stabilität, Widerstandsfähigkeit und Konzentration im Vergleich zu Rinderhämoglobin, ohne Risiko der Rinderwahnsinn-Krankheit. Die Partnerschaft gewährt Bioxytran volle geistige Eigentumsrechte für die Entwicklung des UOC, das ihren führenden Sauerstofftransportmolekül BXT-25 verbessern könnte, das zur Behandlung von Schlaganfall, Demenz, traumatischen Hirnverletzungen und Alzheimer entwickelt wurde. Diese Liefervereinbarung stellt einen strategischen Meilenstein dar, der nicht verwässernde Finanzierung beschleunigen und die Entwicklung der Sauerstofftransporttechnologie vorantreiben könnte.
Positive
  • Secured GMP quality source of camel hemoglobin through $10 million Joint Venture with Heme Foundation
  • Retains full intellectual property rights for UOC development
  • Camel hemoglobin offers superior properties including higher stability and concentration compared to cow alternatives
  • Partnership could unlock additional non-dilutive funding opportunities
  • Supply agreement strengthens development potential for BXT-25 drug candidate
Negative
  • None.

- First use of camel hemoglobin as a universal oxygen carrier

- Unique properties make it an ideal ingredient for oxygen transport

BOSTON, MASSACHUSETTS, June 18, 2025 (GLOBE NEWSWIRE) -- BIOXYTRAN, INC. (OTCQB: BIXT) (the “Company”), a clinical stage biotechnology company developing drugs to treat stroke, Alzheimer’s disease, and viruses, has a secured a GMP quality source of camel hemoglobin with help from the Heme Foundation.

The Heme foundation, dedicated to solving the worlds blood shortages, is partnered with Bioxytran in a $10 million Joint Venture (JV) to develop a Universal Oxygen Carrier (UOC). Through this collaboration, Bioxtyran now has a long-term source of GMP quality camel hemoglobin – a crucial component for advancing this innovative oxygen transport system. Growing interest in the UOC project is expected to drive increased donations to the foundation. Bioxytran is the Heme Foundation’s primary contractor on the UOC project.

Securing a stable and reliable source of GMP quality hemoglobin is vital to the success of the UOC project. Some of the properties of camel hemoglobin make it the ideal building block because there is no perceived threat of mad cow disease compared to cow hemoglobin. Additionally, the half-life of the hemoglobin is significantly higher than a cow when measured in the final production phase. In general, camels have a higher concentration of hemoglobin in their blood cells along with a higher red blood cell count.

Because camels thrive in harsh climates their hemoglobin is more resilient and maintains oxygen carrying capacity even under high temperatures or salt concentrations. The extreme conditions in which they live adapted their hemoglobin to be much more stable than a cow’s. Studies show that camel hemoglobin exhibits lower fluctuation near the heme binding site which means its more stable and has a nominal impact on the oxygen carrying capacity. These efficiencies could boost the overall impact and scalability of the UOC project.

Under the terms of the JV, Bioxytran retains full intellectual property rights for UOC development, which could unlock millions in research advancements applicable to our leading oxygen transport molecule, BXT-25. The drug was designed to permeate blood clots and improve outcomes in a number of indications that include dementia, stroke, Traumatic Brain Injury (TBI), and Alzheimer’s Disease.

“This supply agreement is a major milestone in our long-term strategy for BXT-25 and the UOC,” said David Platt, CEO of Bioxtyran Inc. “Having a reliable supplier not only strengthens our work with the Heme Foundation but could also accelerate non-dilutive funding, fueling innovation in oxygen transport technology. Camel hemoglobin offers powerful advantages and we are excited about this new supplier relationship.”

About the Heme Foundation

The Heme Foundation is a 501(c)(3) nonprofit founded in 2021 and based in Bethlehem, Pennsylvania. Their mission is to provide the world with an alternative for blood transfusions using UOC to eliminate the need for a complex supply chain and to abate the cold chain storage requirements for lifesaving blood transfusions. https://hemefoundation.org/donate/

About Bioxytran, Inc.

Bioxytran, Inc. is at the forefront of developing complex carbohydrate-based therapeutics to address critical unmet medical needs in its three core platform technologies. These include virology, cancer metastasis, and oxygen transport. In addition to ProLectin-M, Bioxytran is advancing programs for pulmonary fibrosis and stroke treatment. When utilized by paramedics at the time of diagnosis BXT-25 has the possibility of reducing what is known as the time until needle by over 90%. For more information, visit www.bioxytraninc.com

Investor Relations
Michael Sheikh
509-991-0245
mike.sheikh@bioxytraninc.com

Forward-Looking Statements

This press release includes forward-looking statements as defined under federal law, including those related to the performance of technology described in this press release. These forward-looking statements are generally identified by the words “believe,” “expect,” “anticipate,” “estimate,” “intend,” “plan,” and similar expressions, although not all forward-looking statements contain these identifying words. Such statements are subject to significant risks, assumptions and uncertainties. Known material factors that could cause Bioxytran’s actual results to differ materially from the results contemplated by such forward-looking statements are described in the forward-looking statements and risk factors in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024, and those risk factors set forth from time-to-time in other filings with the Securities and Exchange Commission. Bioxytran undertakes no obligation to correct or update any forward-looking statement, whether as a result of new information, future events, or otherwise, except to the extent required under federal securities laws.


FAQ

What is the significance of Bioxytran (BIXT) securing camel hemoglobin supply?

The secured GMP quality camel hemoglobin supply is crucial for Bioxytran's $10M Joint Venture to develop a Universal Oxygen Carrier, offering superior properties and stability compared to alternatives, while supporting their BXT-25 drug development program.

How does camel hemoglobin compare to cow hemoglobin for Bioxytran's (BIXT) UOC project?

Camel hemoglobin is more stable, has higher concentration, better resilience to extreme conditions, and poses no mad cow disease risk compared to cow hemoglobin, making it ideal for the UOC project.

What are the potential applications of Bioxytran's (BIXT) BXT-25 drug?

BXT-25 is designed to treat multiple conditions by permeating blood clots, including stroke, dementia, Traumatic Brain Injury (TBI), and Alzheimer's Disease.

What is the partnership structure between Bioxytran (BIXT) and the Heme Foundation?

Bioxytran and the Heme Foundation have formed a $10 million Joint Venture, where Bioxytran serves as the primary contractor and retains full intellectual property rights for UOC development.

How will the camel hemoglobin supply agreement impact Bioxytran's (BIXT) funding?

The supply agreement could accelerate non-dilutive funding opportunities and strengthen Bioxytran's work with the Heme Foundation, supporting innovation in oxygen transport technology.
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