Biomea Fusion to Present Poster Presentations at ObesityWeek®2025

Rhea-AI Summary

Biomea Fusion (Nasdaq:BMEA) will present two poster presentations at ObesityWeek 2025, held November 4-7, 2025 in Atlanta, Georgia.

The posters scheduled for November 4, 2025 at 7:30 p.m. ET cover:

• Poster-085: Preclinical efficacy of BMF-650, an oral small-molecule GLP-1 receptor agonist.
• Poster-136: Icovamenib plus semaglutide: combination data showing enhanced weight loss while preserving lean mass in ZDF rats.

All abstracts will be published in the peer-reviewed Obesity journal supplement and additional information will be provided in line with ObesityWeek abstract embargo policies.

SAN CARLOS, Calif., Oct. 30, 2025 (GLOBE NEWSWIRE) -- Biomea Fusion, Inc. (“Biomea”) (Nasdaq: BMEA), a clinical-stage diabetes and obesity medicines company, today announced that it will present poster presentations at ObesityWeek® 2025, taking place November 4-7, 2025 in Atlanta, Georgia.

The presentations will highlight preclinical data for BMF-650, Biomea’s next-generation oral small molecule glucagon-like peptide-1 (“GLP-1”) receptor agonist (“RA”), and combination data for icovamenib, the company’s first-in-class covalent menin inhibitor, with semaglutide, a GLP-1 based therapy.

Presentation details:

Presentation Poster-085
Title: Preclinical Efficacy of BMF-650 An Oral Small Molecule GLP-1 Receptor Agonist
Presentation Date and Time: November 4, 2025 at 7:30 p.m. - 8:30 p.m. ET

Presentation Poster-136
Title: Icovamenib and Semaglutide Combination Enhances Weight Loss While Preserving Lean Mass in ZDF Rats
Presentation Date and Time: November 4, 2025 at 7:30 p.m. - 8:30 p.m. ET

All abstracts will be published in the peer-reviewed Obesity journal supplement. Biomea will provide additional information in accordance with ObesityWeek® abstract embargo policies.

About Icovamenib
Icovamenib is an investigational, orally bioavailable, potent, and selective covalent inhibitor of menin. The proposed mechanism of action for icovamenib in diabetes is selective and partial inhibition of menin, a regulator of beta cell quantity and function, thereby enabling the proliferation, preservation, and reactivation of a patient’s own healthy, functional, insulin-producing beta cells. As the first non-chronic therapy for T2D, icovamenib could become an important addition to the diabetes treatment landscape once it has successfully completed its ongoing clinical studies.

About BMF-650
BMF-650 is an investigational, next-generation oral small-molecule GLP-1 RA being developed by Biomea Fusion for the treatment of obesity. Related to the broader orforglipron chemotype, BMF-650 is designed to combine enhanced oral bioavailability and durable receptor activation to deliver robust metabolic benefits.

About Biomea Fusion
Biomea Fusion is a clinical-stage diabetes and obesity medicines company focused on the development of its oral small molecule therapies, icovamenib and BMF-650, for diabetes and obesity. These programs target metabolic disorders, a global health challenge affecting nearly half of Americans and one-fifth of the world’s population. Biomea’s mission is to deliver transformative treatments that restore health for patients living with diabetes, obesity, and related conditions. We aim to cure.

Visit us at biomeafusion.com and follow us on LinkedIn, X and Facebook. 

Contact:  
Meichiel Jennifer Weiss  
Sr. Director, Investor Relations and Corporate Development
IR@biomeafusion.com  

FAQ

When and where will Biomea Fusion (BMEA) present at ObesityWeek 2025?

Biomea will present posters on November 4, 2025 at 7:30 p.m. ET during ObesityWeek 2025 in Atlanta, Georgia.

What is BMF-650 that Biomea (BMEA) will present at ObesityWeek 2025?

BMF-650 is described as Biomea's next-generation oral small-molecule GLP-1 receptor agonist with preclinical efficacy data.

What does the Biomea (BMEA) poster say about icovamenib combined with semaglutide?

The poster reports that icovamenib plus semaglutide enhanced weight loss while preserving lean mass in ZDF rat preclinical studies.

Where will Biomea Fusion (BMEA) publish the ObesityWeek 2025 abstracts?

All abstracts will be published in the peer-reviewed Obesity journal supplement.

Will Biomea Fusion (BMEA) release more details after ObesityWeek 2025?

Yes; Biomea will provide additional information in accordance with ObesityWeek abstract embargo policies.