STOCK TITAN

Can-Fite’s Latest Developments of its Advanced Stage Drug Pipeline will be Presented at Noble Capital Markets 21st Annual Emerging Growth Equity Conference

Rhea-AI Impact
(High)
Rhea-AI Sentiment
(Neutral)
Tags

Can-Fite BioPharma (NYSE American: CANF) announced that CEO Motti Farbstein will present at NobleCon21 on Wednesday, December 3, 2025 at 12:30 PM ET in Boca Raton, Florida.

The presentation will cover the company's advanced-stage drug development pipeline, including listed trials: Phase III liver cancer, Phase IIa pancreatic cancer, Phase III psoriasis, Phase IIb MASH, and an upcoming Phase II in Lowe syndrome. The CEO will also hold 1x1 investor meetings.

Can-Fite noted existing out-licensing and global distribution agreements worth up to $130 million for pharma indications and up to $325 million for veterinary indications. A high-definition webcast will be available the following day and archived for 90 days on Can-Fite, NobleCon, and Channelchek websites.

Loading...
Loading translation...

Positive

  • None.

Negative

  • None.

News Market Reaction

%
3 alerts
% News Effect
+2.8% Peak Tracked
$6M Market Cap
0.1x Rel. Volume

On the day this news was published, CANF declined NaN%, reflecting a moderate negative market reaction. Argus tracked a peak move of +2.8% during that session. Our momentum scanner triggered 3 alerts that day, indicating moderate trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

Phase III liver cancer: Phase III Phase IIa pancreatic cancer: Phase IIa Phase III psoriasis: Phase III +4 more
7 metrics
Phase III liver cancer Phase III Advanced-stage liver cancer trial highlighted for NobleCon21
Phase IIa pancreatic cancer Phase IIa Pancreatic cancer trial in development pipeline
Phase III psoriasis Phase III Psoriasis trial in advanced-stage pipeline
Out-licensing pharma up to $130 million Potential value of pharma out-licensing and distribution agreements
Veterinary agreements up to $325 million Potential value of veterinary out-licensing and distribution agreements
Webcast archive period 90 days Duration webcast remains available on company and conference sites
Presentation time 12:30 PM ET Scheduled time for CEO presentation on December 3, 2025

Market Reality Check

Price: $4.47 Vol: Volume 757,871 is at 0.04...
low vol
$4.47 Last Close
Volume Volume 757,871 is at 0.04x the 20-day average of 19,635,464, indicating unusually light trading ahead of the event. low
Technical Shares traded below the 200-day moving average of 0.90, and about 87.59% under the 52-week high.

Peers on Argus

While CANF was down 6.74%, several biotech peers also traded lower, including AD...

While CANF was down 6.74%, several biotech peers also traded lower, including ADAP (-17.57%), CYCC (-5.84%), and MTVA (-9.23%), but the momentum scanner did not flag a coordinated sector move.

Historical Context

5 past events · Latest: Nov 26 (Positive)
Pattern 5 events
Date Event Sentiment Move Catalyst
Nov 26 Conference presentation Positive +0.0% Announcement of NobleCon21 presentation on advanced-stage pipeline and deals.
Nov 24 Partnership outreach Positive +12.0% Pursuit of new veterinary partnerships for Namodenoson at BioFIT 2025.
Nov 20 Patent allowance Positive -7.0% Notice of patent allowance in Brazil for CF602 erectile dysfunction therapy.
Nov 18 Clinical outcome Positive +5.0% Report of 9-year survival and complete response in advanced liver cancer patient.
Sep 15 Clinical breakthrough Positive -2.1% Complete resolution of esophageal varices in decompensated cirrhosis patient.
Pattern Detected

Recent news has been largely positive, yet price reactions were mixed, with three instances of flat or negative moves following favorable announcements.

Recent Company History

Over recent months, Can-Fite reported multiple clinically oriented milestones for Namodenoson, including a 9-year survival case in advanced liver cancer and a complete resolution of esophageal varices, alongside patent progress for CF602 and new veterinary partnering efforts. Capital-raising via a July 424B4 prospectus affected share structure. Against this backdrop, the NobleCon21 presentation mainly reiterates the advanced-stage pipeline and existing out-licensing potential rather than adding new trial data.

Market Pulse Summary

This announcement centers on visibility rather than new data, showcasing Can-Fite’s advanced-stage p...
Analysis

This announcement centers on visibility rather than new data, showcasing Can-Fite’s advanced-stage pipeline—spanning Phase III liver cancer and psoriasis and Phase II studies in pancreatic cancer and MASH—along with out-licensing agreements potentially worth up to $130 million for pharma and $325 million for veterinary uses. Investors may track future clinical readouts, additional partnership agreements, and any follow-up to the NobleCon21 meetings and webcast as catalysts.

Key Terms

phase iii, phase iia, phase iib, out-licensing
4 terms
phase iii medical
"including the following trials: Phase III liver cancerPhase IIa pancreatic cancerPhase III"
A Phase III trial is the late-stage clinical study that tests whether a medical treatment works and is safe in a large group of patients, often comparing it to standard care. Think of it as a final dress rehearsal or full-scale road test before regulators decide on approval; positive or negative results strongly influence a drug maker’s chance to sell the treatment, future revenue, and investment risk.
phase iia medical
"trials: Phase III liver cancerPhase IIa pancreatic cancerPhase III psoriasisPhase IIb"
Phase IIa is an early mid-stage clinical study that tests whether a new drug or treatment shows the intended biological effect in patients and helps identify the best dose. Think of it as a focused test-drive to see if a medicine does what it’s supposed to and what dose is tolerable before larger trials. Investors watch Phase IIa results because positive findings reduce technical risk and can materially increase the program’s value, while negative results raise the likelihood of costly delays or failure.
phase iib medical
"pancreatic cancerPhase III psoriasisPhase IIb MASHUpcoming Phase II in Lowe Syndrome"
Phase IIb is a mid-stage clinical trial that tests whether an experimental treatment works and what dose is best by studying it in a larger group of patients than early tests. For investors, Phase IIb results are important because they substantially reduce uncertainty about a drug’s effectiveness and safety, and positive or negative outcomes often drive company valuation, partnership interest, and the likelihood of advancing to the large, costly Phase III trials.
out-licensing financial
"Can-Fite has numerous out-licensing and global distribution agreements in place worth"
Out-licensing is when a company grants another firm the right to develop, manufacture or sell a product or technology in exchange for upfront payments, milestone fees and ongoing royalties. Think of it like leasing a recipe to a larger kitchen so they handle production and sales while the original owner collects steady income and reduces costs and risk. For investors, out-licensing can speed commercialization, create near-term revenue, lower development expenses, and shift where future profits and growth will come from.

AI-generated analysis. Not financial advice.

RAMAT GAN, Israel, Nov. 26, 2025 (GLOBE NEWSWIRE) --  Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE: CANF), a biotechnology company advancing a pipeline of proprietary small molecule drugs targeting oncological and inflammatory diseases, announced today that its CEO, Motti Farbstein will present at NobleCon21—Noble Capital Markets’ Twenty First Annual Emerging Growth Equity Conference—at Florida Atlantic University, Executive Education Complex, in Boca Raton, Floria—on Wednesday, December 3rd, 2025 at 12:30 PM ET. Mr. Farbstein will also conduct 1x1 meetings with investors.

Mr. Farbstein will present the latest developments in Can-Fite’s advanced stage drug development pipeline including the following trials:

  • Phase III liver cancer
  • Phase IIa pancreatic cancer
  • Phase III psoriasis
  • Phase IIb MASH
  • Upcoming Phase II in Lowe Syndrome

Can-Fite has numerous out-licensing and global distribution agreements in place worth up to $130 million for pharma indications, with an additional up to $325 million for veterinary indications.

A high-definition video webcast of the presentation will be available the following day on Can-Fite's website www.canfite.com, and as part of a complete catalog of presentations available at Noble Capital Markets’ Conference website at www.nobleconference.com and on Channelchek www.channelchek.com, the investor portal created by Noble. The webcast will be archived on Can-Fite’s website, the NobleCon website, and on Channelchek.com for 90 days following the event. 

About Can-Fite BioPharma Ltd.

Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE: CANF) is an advanced clinical stage drug development Company with a platform technology that is designed to address multi-billion-dollar markets in the treatment of cancer, liver, and inflammatory disease. The Company's lead drug candidate, Piclidenoson reported topline results in a Phase III trial for psoriasis and commenced a pivotal Phase III trial. Can-Fite's liver drug, Namodenoson, is being evaluated in a Phase III trial for hepatocellular carcinoma (HCC), a Phase IIb trial for the treatment of MASH, and in a Phase IIa study in pancreatic cancer. Namodenoson has been granted Orphan Drug Designation in the U.S. and Europe and Fast Track Designation as a second line treatment for HCC by the U.S. Food and Drug Administration. Namodenoson has also shown proof of concept to potentially treat other cancers including colon, prostate, and melanoma. CF602, the Company's third drug candidate, has shown efficacy in the treatment of erectile dysfunction. These drugs have an excellent safety profile with experience in over 1,600 patients in clinical studies to date. For more information please visit: https://www.canfite.com/.

Forward-Looking Statements

This press release contains forward-looking statements, about Can-Fite’s expectations, beliefs or intentions regarding, among other things, its product development efforts, business, financial condition, results of operations, strategies or revenue prospects. All statements in this communication, other than those relating to historical facts, are “forward looking statements”. Forward-looking statements can be identified by the use of forward-looking words such as “believe,” “expect,” “intend,” “plan,” “may,” “should” or “anticipate” or their negatives or other variations of these words or other comparable words or by the fact that these statements do not relate strictly to historical or current matters. Forward-looking statements relate to anticipated or expected events, activities, trends or results as of the date they are made. Because forward-looking statements relate to matters that have not yet occurred, these statements are inherently subject to known and unknown risks, uncertainties and other factors that may cause Can-Fite’s actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Important factors that could cause actual results, performance or achievements to differ materially from those anticipated in these forward-looking statements include, among other things, our history of losses and needs for additional capital to fund our operations and our inability to obtain additional capital on acceptable terms, or at all; uncertainties of cash flows and inability to meet working capital needs; the initiation, timing, progress and results of our preclinical studies, clinical trials and other product candidate development efforts; our ability to advance our product candidates into clinical trials or to successfully complete our preclinical studies or clinical trials; our receipt of regulatory approvals for our product candidates, and the timing of other regulatory filings and approvals; the clinical development, commercialization and market acceptance of our product candidates; our ability to establish and maintain strategic partnerships and other corporate collaborations; the implementation of our business model and strategic plans for our business and product candidates; the scope of protection we are able to establish and maintain for intellectual property rights covering our product candidates and our ability to operate our business without infringing the intellectual property rights of others; competitive companies, technologies and our industry; risks related to any resurgence of the COVID-19 pandemic and the war between Israel and Hamas; risks related to not satisfying the continued listing requirements of NYSE American; and statements as to the impact of the political and security situation in Israel on our business. More information on these risks, uncertainties and other factors is included from time to time in the “Risk Factors” section of Can-Fite’s Annual Report on Form 20-F filed with the SEC on April 14, 2025 and other public reports filed with the SEC and in its periodic filings with the TASE. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. Can-Fite undertakes no obligation to publicly update or review any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by any applicable securities laws.

Contact

Can-Fite BioPharma

Motti Farbstein

info@canfite.com

+972-3-9241114


FAQ

When will Can-Fite (CANF) present at NobleCon21 and who is presenting?

Can-Fite CEO Motti Farbstein will present on December 3, 2025 at 12:30 PM ET.

What CANF clinical programs will be covered in the December 3, 2025 presentation?

The presentation will cover Phase III liver cancer, Phase IIa pancreatic cancer, Phase III psoriasis, Phase IIb MASH, and an upcoming Phase II in Lowe syndrome.

Will Can-Fite (CANF) provide a webcast of the NobleCon21 presentation?

Yes; a high-definition webcast will be available the following day and archived for 90 days on Can-Fite, NobleCon, and Channelchek websites.

Does Can-Fite (CANF) have commercialization or licensing agreements mentioned for investors?

Yes; Can-Fite cited out-licensing and global distribution agreements worth up to $130 million for pharma and up to $325 million for veterinary indications.

Will Can-Fite CEO hold investor meetings at NobleCon21 on December 3, 2025?

Yes; the CEO is scheduled to conduct one-on-one investor meetings in addition to the presentation.

Where can investors find past and archived Can-Fite (CANF) NobleCon21 materials?

Archived materials will be available on Can-Fite's website, the NobleCon conference website, and Channelchek for 90 days after the event.
Can-Fite BioPharma Ltd.

NYSE:CANF

CANF Rankings

CANF Latest News

CANF Latest SEC Filings

CANF Stock Data

3.55M
853.65k
5.89%
1.13%
Biotechnology
Healthcare
Link
Israel
Ramat Gan