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Can-Fite’s Latest Developments of its Advanced Stage Drug Pipeline will be Presented at Noble Capital Markets 21st Annual Emerging Growth Equity Conference

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Can-Fite BioPharma (NYSE American: CANF) announced that CEO Motti Farbstein will present at NobleCon21 on Wednesday, December 3, 2025 at 12:30 PM ET in Boca Raton, Florida.

The presentation will cover the company's advanced-stage drug development pipeline, including listed trials: Phase III liver cancer, Phase IIa pancreatic cancer, Phase III psoriasis, Phase IIb MASH, and an upcoming Phase II in Lowe syndrome. The CEO will also hold 1x1 investor meetings.

Can-Fite noted existing out-licensing and global distribution agreements worth up to $130 million for pharma indications and up to $325 million for veterinary indications. A high-definition webcast will be available the following day and archived for 90 days on Can-Fite, NobleCon, and Channelchek websites.

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RAMAT GAN, Israel, Nov. 26, 2025 (GLOBE NEWSWIRE) --  Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE: CANF), a biotechnology company advancing a pipeline of proprietary small molecule drugs targeting oncological and inflammatory diseases, announced today that its CEO, Motti Farbstein will present at NobleCon21—Noble Capital Markets’ Twenty First Annual Emerging Growth Equity Conference—at Florida Atlantic University, Executive Education Complex, in Boca Raton, Floria—on Wednesday, December 3rd, 2025 at 12:30 PM ET. Mr. Farbstein will also conduct 1x1 meetings with investors.

Mr. Farbstein will present the latest developments in Can-Fite’s advanced stage drug development pipeline including the following trials:

  • Phase III liver cancer
  • Phase IIa pancreatic cancer
  • Phase III psoriasis
  • Phase IIb MASH
  • Upcoming Phase II in Lowe Syndrome

Can-Fite has numerous out-licensing and global distribution agreements in place worth up to $130 million for pharma indications, with an additional up to $325 million for veterinary indications.

A high-definition video webcast of the presentation will be available the following day on Can-Fite's website www.canfite.com, and as part of a complete catalog of presentations available at Noble Capital Markets’ Conference website at www.nobleconference.com and on Channelchek www.channelchek.com, the investor portal created by Noble. The webcast will be archived on Can-Fite’s website, the NobleCon website, and on Channelchek.com for 90 days following the event. 

About Can-Fite BioPharma Ltd.

Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE: CANF) is an advanced clinical stage drug development Company with a platform technology that is designed to address multi-billion-dollar markets in the treatment of cancer, liver, and inflammatory disease. The Company's lead drug candidate, Piclidenoson reported topline results in a Phase III trial for psoriasis and commenced a pivotal Phase III trial. Can-Fite's liver drug, Namodenoson, is being evaluated in a Phase III trial for hepatocellular carcinoma (HCC), a Phase IIb trial for the treatment of MASH, and in a Phase IIa study in pancreatic cancer. Namodenoson has been granted Orphan Drug Designation in the U.S. and Europe and Fast Track Designation as a second line treatment for HCC by the U.S. Food and Drug Administration. Namodenoson has also shown proof of concept to potentially treat other cancers including colon, prostate, and melanoma. CF602, the Company's third drug candidate, has shown efficacy in the treatment of erectile dysfunction. These drugs have an excellent safety profile with experience in over 1,600 patients in clinical studies to date. For more information please visit: https://www.canfite.com/.

Forward-Looking Statements

This press release contains forward-looking statements, about Can-Fite’s expectations, beliefs or intentions regarding, among other things, its product development efforts, business, financial condition, results of operations, strategies or revenue prospects. All statements in this communication, other than those relating to historical facts, are “forward looking statements”. Forward-looking statements can be identified by the use of forward-looking words such as “believe,” “expect,” “intend,” “plan,” “may,” “should” or “anticipate” or their negatives or other variations of these words or other comparable words or by the fact that these statements do not relate strictly to historical or current matters. Forward-looking statements relate to anticipated or expected events, activities, trends or results as of the date they are made. Because forward-looking statements relate to matters that have not yet occurred, these statements are inherently subject to known and unknown risks, uncertainties and other factors that may cause Can-Fite’s actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Important factors that could cause actual results, performance or achievements to differ materially from those anticipated in these forward-looking statements include, among other things, our history of losses and needs for additional capital to fund our operations and our inability to obtain additional capital on acceptable terms, or at all; uncertainties of cash flows and inability to meet working capital needs; the initiation, timing, progress and results of our preclinical studies, clinical trials and other product candidate development efforts; our ability to advance our product candidates into clinical trials or to successfully complete our preclinical studies or clinical trials; our receipt of regulatory approvals for our product candidates, and the timing of other regulatory filings and approvals; the clinical development, commercialization and market acceptance of our product candidates; our ability to establish and maintain strategic partnerships and other corporate collaborations; the implementation of our business model and strategic plans for our business and product candidates; the scope of protection we are able to establish and maintain for intellectual property rights covering our product candidates and our ability to operate our business without infringing the intellectual property rights of others; competitive companies, technologies and our industry; risks related to any resurgence of the COVID-19 pandemic and the war between Israel and Hamas; risks related to not satisfying the continued listing requirements of NYSE American; and statements as to the impact of the political and security situation in Israel on our business. More information on these risks, uncertainties and other factors is included from time to time in the “Risk Factors” section of Can-Fite’s Annual Report on Form 20-F filed with the SEC on April 14, 2025 and other public reports filed with the SEC and in its periodic filings with the TASE. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. Can-Fite undertakes no obligation to publicly update or review any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by any applicable securities laws.

Contact

Can-Fite BioPharma

Motti Farbstein

info@canfite.com

+972-3-9241114


FAQ

When will Can-Fite (CANF) present at NobleCon21 and who is presenting?

Can-Fite CEO Motti Farbstein will present on December 3, 2025 at 12:30 PM ET.

What CANF clinical programs will be covered in the December 3, 2025 presentation?

The presentation will cover Phase III liver cancer, Phase IIa pancreatic cancer, Phase III psoriasis, Phase IIb MASH, and an upcoming Phase II in Lowe syndrome.

Will Can-Fite (CANF) provide a webcast of the NobleCon21 presentation?

Yes; a high-definition webcast will be available the following day and archived for 90 days on Can-Fite, NobleCon, and Channelchek websites.

Does Can-Fite (CANF) have commercialization or licensing agreements mentioned for investors?

Yes; Can-Fite cited out-licensing and global distribution agreements worth up to $130 million for pharma and up to $325 million for veterinary indications.

Will Can-Fite CEO hold investor meetings at NobleCon21 on December 3, 2025?

Yes; the CEO is scheduled to conduct one-on-one investor meetings in addition to the presentation.

Where can investors find past and archived Can-Fite (CANF) NobleCon21 materials?

Archived materials will be available on Can-Fite's website, the NobleCon conference website, and Channelchek for 90 days after the event.
Can-Fite BioPharma Ltd.

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