Welcome to our dedicated page for Compugen news (Ticker: CGEN), a resource for investors and traders seeking the latest updates and insights on Compugen stock.
Compugen Ltd. develops cancer immunotherapy programs using its AI/ML-powered Unigen computational discovery capabilities to identify drug targets and biological pathways. News about CGEN commonly covers clinical and preclinical immuno-oncology programs, including COM701, COM902, rilvegostomig and GS-0321, as well as updates tied to immune-checkpoint targets such as PVRIG, TIGIT and IL-18 binding protein.
Recurring company developments include quarterly and annual financial results, corporate updates, scientific conference presentations, clinical data disclosures, partnership activity with AstraZeneca and Gilead, royalty and license arrangements, and board or leadership changes. Compugen's ordinary shares trade on Nasdaq and the Tel Aviv Stock Exchange under the ticker CGEN.
Compugen Ltd. (CGEN) has announced the dosing of the first patient in a Phase 1 clinical study assessing the combination of its anti-TIGIT antibody, COM902, and anti-PVRIG antibody, COM701, in patients with advanced malignancies. The study aims to evaluate safety, tolerability, pharmacokinetics, and preliminary antitumor activity in patients who have exhausted standard therapies. Initial results from the COM902 monotherapy study are expected in Q4 2021. Compugen's strategy focuses on expanding immunotherapy effectiveness through dual blockade of PVRIG and TIGIT pathways.
Compugen Ltd. (Nasdaq: CGEN) announces it will release its second quarter 2021 financial results on July 28, 2021, before U.S. markets open. Management will host a conference call and webcast at 8:30 AM ET to discuss the results and provide a corporate update. The call can be accessed via telephone or through a live webcast on the company's website. Compugen is focused on cancer immunotherapy with key products like COM701 and COM902 undergoing clinical studies.
Compugen Ltd. (NASDAQ: CGEN) has announced the dosing of the first patient in a combination expansion cohort of its Phase 1 clinical trial for COM701, an anti-PVRIG antibody, in conjunction with Opdivo® (nivolumab). This cohort targets ovarian, breast, endometrial, and colorectal cancers, following encouraging initial results showing complete responses and durable anti-tumor activity. The trial aims to evaluate the safety and efficacy of the therapy in advanced solid tumors, reinforcing Compugen's position in cancer immunotherapy.
Compugen Ltd. (CGEN) presented new research on PVRIG, emphasizing its role as a distinct immune checkpoint that may enhance T-cell expansion. Findings suggest that PVRIG clusters with early memory T cell markers, indicating its potential when used with TIGIT and PD-1 inhibitors for tumors unresponsive to current therapies. The study highlights PVRIG's expression in T cells and its potential to trigger immune responses. The presentation was made at the SITC 2021 seminar.
Compugen Ltd. (Nasdaq: CGEN) presented updated data from its Phase 1 study of COM701, a first-in-class anti-PVRIG antibody, at ASCO 2021. The combination of COM701 with Opdivo® demonstrated a 66.7% disease control rate in 15 evaluable patients, with a notable complete response in a patient with anal squamous cell carcinoma lasting 22 months. The monotherapy showed a 47.2% disease control rate across 36 patients, with preliminary biomarker data indicating enhanced immune response. These findings highlight the potential for COM701 in difficult-to-treat cancers, including ongoing evaluation in immunotherapy-resistant populations.
Compugen Ltd. (Nasdaq: CGEN) announced participation in a virtual event to discuss data from its Phase 1 clinical trial of COM701, an innovative antibody targeting PVRIG. The findings will be presented on June 7, 2021, at the ASCO 2021 Annual Meeting. A fireside chat hosted by Truist Securities analyst Asthika Goonewardene is scheduled for June 8, 2021, featuring key executives from Compugen. The company is focused on developing cancer immunotherapy treatments, including the ongoing studies of COM701 and COM902.
Compugen Ltd. (CGEN) reported Q1 2021 financial results with a net loss of $9.9 million or $0.12 per share, an increase from a $7.1 million loss in Q1 2020. R&D expenses rose to $7.3 million, up from $4.7 million, driven by drug manufacturing and clinical activities. The company has $119.4 million in cash reserves. Upcoming milestones include data readouts for COM701 in various studies and collaboration with Bristol Myers Squibb for a Phase 1b study. Compugen aims to lead in the DNAM axis space with promising clinical data for PVRIG and TIGIT assets.
Compugen Ltd. (NASDAQ: CGEN) announced that Eran Ophir, Ph.D., Vice President of Research and Drug Discovery, will participate in the Society for Immunotherapy of Cancer's online seminar on June 29, 2021. The seminar focuses on 'The TIGIT Pathway' and is part of a series addressing key questions in cancer immunotherapy. Co-chairs include industry experts, and an interactive Q&A session will follow. Compugen, based in Israel, is developing innovative cancer therapies, including its lead anti-PVRIG antibody, COM701, currently in Phase 1 trials.
Compugen Ltd. (CGEN) announced an expansion of its research collaboration with Johns Hopkins University on a novel myeloid target discovered through its predictive computational platform. Initial preclinical studies indicate significant tumor growth inhibition upon genetic deletion of this target, potentially serving as a myeloid immunomodulator. The collaboration aims to further investigate the biological function of this target, enhancing Compugen's immuno-oncology pipeline. The CEO emphasizes the importance of early-stage programs for the company's growth and development in cancer therapies.
Compugen Ltd. (Nasdaq: CGEN), a clinical-stage cancer immunotherapy company, will release its first quarter 2021 financial results on May 13, 2021, before U.S. markets open. A conference call will be held at 8:30 AM ET to discuss the results and provide an update. Investors can join via telephone or through a live webcast on Compugen's website. The company is advancing its lead candidate, COM701, an anti-PVRIG antibody for solid tumors, which is currently in a Phase 1 clinical study, alongside COM902, targeting TIGIT.